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An Okinawan-based Nordic diet improves anthropometry, metabolic control, and health-related quality of life in Scandinavian patients with type 2 diabetes : A pilot trial

Darwiche, Gassan LU ; Höglund, Peter LU ; Roth, Bodil LU ; Larsson, Ewa LU ; Sjöberg, Trygve LU ; Wohlfart, Björn LU ; Steen, Stig LU and Ohlsson, Bodil LU (2016) In Food and Nutrition Research 60.
Abstract

Background: Our hypothesis was that a modified diet would improve blood glucose control with beneficial impact on weight management and overall health in established diabetes. Objective: This prospective interventional study investigated the clinical effect of an Okinawan-based Nordic diet on anthropometry, metabolic control, and health-related quality of life (HRQoL) in Scandinavian type 2 diabetes patients. Design: Food was prepared and delivered to 30 type 2 diabetes patients. Clinical information along with data on HRQoL, blood samples, and urine samples were collected during 12 weeks of diet interventions, with follow-up 16 weeks after diet completion. Results: After 12 weeks of dietary intervention, a reduction in body weight (7%)... (More)

Background: Our hypothesis was that a modified diet would improve blood glucose control with beneficial impact on weight management and overall health in established diabetes. Objective: This prospective interventional study investigated the clinical effect of an Okinawan-based Nordic diet on anthropometry, metabolic control, and health-related quality of life (HRQoL) in Scandinavian type 2 diabetes patients. Design: Food was prepared and delivered to 30 type 2 diabetes patients. Clinical information along with data on HRQoL, blood samples, and urine samples were collected during 12 weeks of diet interventions, with follow-up 16 weeks after diet completion. Results: After 12 weeks of dietary intervention, a reduction in body weight (7%) (p < 0.001), body mass index (p < 0.001), and waist circumference (7.0 cm) (p < 0.001) was seen. Improved levels of proinsulin (p = 0.005), insulin (p = 0.011), and fasting plasma glucose (p < 0.001) were found already after 2 weeks; these improved levels remained after 12 weeks when lowered levels of C-peptide (p = 0.015), triglycerides (p = 0.009), total cholesterol (p = 0.001), and low-density lipoprotein-cholesterol (p = 0.041) were also observed. Insulin resistance homeostasis model assessment for insulin resistance was lowered throughout the study, with a 20% reduction in hemoglobin A1c levels (p < 0.001) at week 12, despite reduced anti-diabetes treatment. Lowered systolic blood pressure (9.6 mmHg) (p < 0.001), diastolic blood pressure (2.7 mmHg) (p < 0.001), and heart and respiratory rates (p < 0.001) were accompanied by decreased cortisol levels (p = 0.015) and improvement in HRQoL. At follow-up, increased levels of high-density lipoprotein-cholesterol were found (p = 0.003). Conclusion: This interventional study demonstrates a considerable improvement of anthropometric and metabolic parameters and HRQoL in Scandinavian type 2 diabetes patients when introducing a modified Okinawan-based Nordic diet, independently of exercise or other interventions. Through these dietary changes, anti-diabetes treatment could be decreased or cancelled.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Anthropometry, Interventional study, Metabolic control, Nordic diet, Okinawan diet, Quality of life, Type 2 diabetes
in
Food and Nutrition Research
volume
60
publisher
Co-action Publishing
external identifiers
  • scopus:84990934163
  • wos:000396878900001
ISSN
1654-6628
DOI
10.3402/fnr.v60.32594
language
English
LU publication?
yes
id
40058680-3487-463b-947a-2bbfa33e0bb6
date added to LUP
2016-11-03 07:16:49
date last changed
2017-09-18 11:29:01
@article{40058680-3487-463b-947a-2bbfa33e0bb6,
  abstract     = {<p>Background: Our hypothesis was that a modified diet would improve blood glucose control with beneficial impact on weight management and overall health in established diabetes. Objective: This prospective interventional study investigated the clinical effect of an Okinawan-based Nordic diet on anthropometry, metabolic control, and health-related quality of life (HRQoL) in Scandinavian type 2 diabetes patients. Design: Food was prepared and delivered to 30 type 2 diabetes patients. Clinical information along with data on HRQoL, blood samples, and urine samples were collected during 12 weeks of diet interventions, with follow-up 16 weeks after diet completion. Results: After 12 weeks of dietary intervention, a reduction in body weight (7%) (p &lt; 0.001), body mass index (p &lt; 0.001), and waist circumference (7.0 cm) (p &lt; 0.001) was seen. Improved levels of proinsulin (p = 0.005), insulin (p = 0.011), and fasting plasma glucose (p &lt; 0.001) were found already after 2 weeks; these improved levels remained after 12 weeks when lowered levels of C-peptide (p = 0.015), triglycerides (p = 0.009), total cholesterol (p = 0.001), and low-density lipoprotein-cholesterol (p = 0.041) were also observed. Insulin resistance homeostasis model assessment for insulin resistance was lowered throughout the study, with a 20% reduction in hemoglobin A1c levels (p &lt; 0.001) at week 12, despite reduced anti-diabetes treatment. Lowered systolic blood pressure (9.6 mmHg) (p &lt; 0.001), diastolic blood pressure (2.7 mmHg) (p &lt; 0.001), and heart and respiratory rates (p &lt; 0.001) were accompanied by decreased cortisol levels (p = 0.015) and improvement in HRQoL. At follow-up, increased levels of high-density lipoprotein-cholesterol were found (p = 0.003). Conclusion: This interventional study demonstrates a considerable improvement of anthropometric and metabolic parameters and HRQoL in Scandinavian type 2 diabetes patients when introducing a modified Okinawan-based Nordic diet, independently of exercise or other interventions. Through these dietary changes, anti-diabetes treatment could be decreased or cancelled.</p>},
  articleno    = {32594},
  author       = {Darwiche, Gassan and Höglund, Peter and Roth, Bodil and Larsson, Ewa and Sjöberg, Trygve and Wohlfart, Björn and Steen, Stig and Ohlsson, Bodil},
  issn         = {1654-6628},
  keyword      = {Anthropometry,Interventional study,Metabolic control,Nordic diet,Okinawan diet,Quality of life,Type 2 diabetes},
  language     = {eng},
  month        = {09},
  publisher    = {Co-action Publishing},
  series       = {Food and Nutrition Research},
  title        = {An Okinawan-based Nordic diet improves anthropometry, metabolic control, and health-related quality of life in Scandinavian patients with type 2 diabetes : A pilot trial},
  url          = {http://dx.doi.org/10.3402/fnr.v60.32594},
  volume       = {60},
  year         = {2016},
}