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- 2024
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Mark
Serum ARGS-aggrecan in a phase 2 clinical trial targeting osteoarthritis
(
- Contribution to journal › Article
- 2023
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Mark
The Effects of Different Management Strategies or Rehabilitation Approaches on Knee Joint Structural and Molecular Biomarkers Following Traumatic Knee Injury : A Systematic Review of Randomized Controlled Trials for the OPTIKNEE Consensus
(
- Contribution to journal › Scientific review
- 2022
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Mark
Safety, Pharmacokinetics, and Pharmacodynamics of the ADAMTS-5 Inhibitor GLPG1972/S201086 in Healthy Volunteers and Participants With Osteoarthritis of the Knee or Hip
(
- Contribution to journal › Article
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Mark
Biological variation of human aggrecan ARGS neoepitope in synovial fluid and serum in early-stage knee osteoarthritis and after knee injury
(
- Contribution to journal › Article
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Mark
Technical performance of a proximity extension assay inflammation biomarker panel with synovial fluid
(
- Contribution to journal › Article
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Mark
The alarmins high mobility group box protein 1 and S100A8/A9 display different inflammatory profiles after acute knee injury
(
- Contribution to journal › Article
- 2021
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Mark
An Anterior Cruciate Ligament Rupture Increases Levels of Urine N-terminal Cross-linked Telopeptide of Type I Collagen, Urine C-terminal Cross-linked Telopeptide of Type II Collagen, Serum Aggrecan ARGS Neoepitope, and Serum Tumor Necrosis Factor–α
(
- Contribution to journal › Article
- 2020
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Mark
Molecular and imaging biomarkers of local inflammation at 2 years after anterior cruciate ligament injury do not associate with patient reported outcomes at 5 years
(
- Contribution to journal › Article
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Mark
Higher aggrecan 1-F21 epitope concentration in synovial fluid early after anterior cruciate ligament injury is associated with worse knee cartilage quality assessed by gadolinium enhanced magnetic resonance imaging 20 years later
(
- Contribution to journal › Article
- 2019
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Mark
Molecular and Structural Biomarkers of Inflammation at Two Years After Acute Anterior Cruciate Ligament Injury Do Not Predict Structural Knee Osteoarthritis at Five Years
(
- Contribution to journal › Article
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Mark
Impact of exercise therapy on molecular biomarkers related to cartilage and inflammation in people at risk of, or with established, knee osteoarthritis : a systematic review and meta-analysis of randomized controlled trials
2019) In Arthritis care and research : the official journal of the Arthritis Health Professions Association 71(11). p.1504-1515(
- Contribution to journal › Article
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Mark
Reply to letter by Deng et al. "Could the levels of inflammation biomarkers predict OA? : Comment on the article by Roemer FW et al."
(
- Contribution to journal › Letter
- 2018
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Mark
α1-microglobulin protects against bleeding-induced oxidative damage in knee arthropathies
(
- Contribution to journal › Article
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Mark
Time between anterior cruciate ligament injury and reconstruction and cartilage metabolism six-months following reconstruction
(
- Contribution to journal › Article
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Mark
Changes in synovial fluid and serum concentrations of cartilage oligomeric matrix protein over 5 years after anterior cruciate ligament rupture : an exploratory analysis in the KANON trial
(
- Contribution to journal › Article
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Mark
Dickkopf-related protein 1 and gremlin 1 show different response than frizzled-related protein in human synovial fluid following knee injury and in patients with osteoarthritis
(
- Contribution to journal › Article
- 2017
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Mark
Surgical reconstruction of ruptured anterior cruciate ligament prolongs trauma-induced increase of inflammatory cytokines in synovial fluid : An exploratory analysis in the KANON trial
(
- Contribution to journal › Article
- 2015
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Mark
Interleukin-6 and tumor necrosis factor alpha in synovial fluid are associated with progression of radiographic knee osteoarthritis in subjects with previous meniscectomy.
(
- Contribution to journal › Article
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Mark
Type II collagen C2C epitope in human synovial fluid and serum after knee injury - associations with molecular and structural markers of injury.
(
- Contribution to journal › Article
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Mark
Changes in synovial fluid and serum cytokines and ARGS-aggrecan, and urine CTX-II and NTX-I over five years after anterior cruciate ligament rupture: An exploratory analysis in the KANON trial.
(
- Contribution to journal › Article
- 2014
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Mark
An ARGS-aggrecan assay for analysis in blood and synovial fluid.
(
- Contribution to journal › Article
- 2012
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Mark
The association between changes in synovial fluid levels of ARGS-aggrecan fragments, progression of radiographic osteoarthritis and self-reported outcomes: a cohort study.
(
- Contribution to journal › Article
- 2011
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Mark
Elevated aggrecanase activity in a rat model of joint injury is attenuated by an aggrecanase specific inhibitor
(
- Contribution to journal › Article
- 2010
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Mark
Aggrecan fragments as biomarkers in osteoarthritis
(
- Thesis › Doctoral thesis (compilation)
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Mark
The association between synovial fluid levels of aggrecan ARGS fragments and radiographic progression of knee osteoarthritis
2010) World Congress of the OsteoArthritis-Research-Society-International In Osteoarthritis and Cartilage 18(Supplement 2). p.59-60(
- Contribution to journal › Published meeting abstract
-
Mark
A comparison of different purification methods of aggrecan fragments from human articular cartilage and synovial fluid.
(
- Contribution to journal › Article
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Mark
Association between synovial fluid levels of aggrecan ARGS fragments and radiographic progression in knee osteoarthritis.
(
- Contribution to journal › Article
- 2009
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Mark
Synovial fluid level of aggrecan ARGS fragments is a more sensitive marker of joint disease than glycosaminoglycan or aggrecan levels: a cross-sectional study
(
- Contribution to journal › Article
-
Mark
Western blot quantification of aggrecan fragments in human synovial fluid indicates differences in fragment patterns between joint diseases.
(
- Contribution to journal › Article
- 2006
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Mark
Estimation of the identity of proteolytic aggrecan fragments using PAGE migration and Western immunoblot.
(
- Contribution to journal › Article
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Mark
Development and characterization of a highly specific and sensitive sandwich ELISA for detection of aggrecanase-generated aggrecan fragments
(
- Contribution to journal › Article
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Mark
Human osteoarthritis synovial fluid and joint cartilage contain both aggrecanase- and matrix metalloproteinase-generated aggrecan fragments.
(
- Contribution to journal › Article
- 2005
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Mark
Use of the plasma stromelysin (matrix metalloproteinase 3) concentration to predict joint space narrowing in knee osteoarthritis.
(
- Contribution to journal › Article
- 2003
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Mark
Human CD34+ hematopoietic stem cells capable of multilineage engrafting NOD/SCID mice express flt3: distinct flt3 and c-kit expression and response patterns on mouse and candidate human hematopoietic stem cells.
(
- Contribution to journal › Article