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- 2020
- Inhibition of AMPK activity in response to insulin in adipocytes : involvement of AMPK pS485, PDEs, and cellular energy levels (
- Inner ear is a target for insulin signaling and insulin resistance : evidence from mice and auditory HEI-OC1 cells (
- Persistent whole day meal effects of three dipeptidyl peptidase-4 inhibitors on glycaemia and hormonal responses in metformin-treated type 2 diabetes (
- Knockout of the radical scavenger α1-microglobulin in mice results in defective bikunin synthesis, endoplasmic reticulum stress and increased body weight (
- JUP/plakoglobin is regulated by salt-inducible kinase 2, and is required for insulin-induced signalling and glucose uptake in adipocytes (
- 2019
- Insulin induces Thr484 phosphorylation and stabilization of SIK2 in adipocytes (
- Salt-inducible kinase 2 regulates TFEB and is required for autophagic flux in adipocytes (
- Chemical genetic screen identifies Gapex-5/GAPVD1 and STBD1 as novel AMPK substrates (
- EHD2 regulates adipocyte function and is enriched at cell surface-associated lipid droplets in primary human adipocytes (
- 2018
- Intact glucose uptake despite deteriorating signaling in adipocytes with high-fat feeding (
- Effect of single-dose DPP-4 inhibitor sitagliptin on β-cell function and incretin hormone secretion after meal ingestion in healthy volunteers and drug-naïve, well-controlled type 2 diabetes subjects (
- The Salt-Inducible Kinases : Emerging Metabolic Regulators (
- AMPK activation by A-769662 and 991 does not affect catecholamine-induced lipolysis in human adipocytes (
- 2017
- Salt-inducible kinase 2 and -3 are downregulated in adipose tissue from obese or insulin-resistant individuals : implications for insulin signalling and glucose uptake in human adipocytes (
- GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis (
- Rosiglitazone drives cavin-2/SDPR expression in adipocytes in a CEBPα-dependent manner (
- Visualization of lipid directed dynamics of perilipin 1 in human primary adipocytes (
- 2016
- Parathyroid hormone induces adipocyte lipolysis via PKA-mediated phosphorylation of hormone-sensitive lipase. (
- Transcriptional regulation of the miR-212/miR-132 cluster in insulin-secreting β-cells by cAMP-regulated transcriptional co-activator 1 and salt-inducible kinases. (
- HMGB1 binds to the rs7903146 locus in TCF7L2 in human pancreatic islets. (
- SIKs control osteocyte responses to parathyroid hormone (
- 2015
- Detrusor Induction of miR-132/212 following Bladder Outlet Obstruction: Association with MeCP2 Repression and Cell Viability. (
- SIK2 regulates CRTCs, HDAC4 and glucose uptake in adipocytes (
- ApoA-I Milano stimulates lipolysis in adipose cells independently of cAMP/PKA activation. (
- The Academic Librarians' Support to PhD students' Portfolio Work : Third space - a meeting point for professionals and academics in higher education (
- 2014
- The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver. (
- Single injections of apoA-I acutely improve in vivo glucose tolerance in insulin-resistant mice. (
- LKB1 signalling attenuates early events of adipogenesis and responds to adipogenic cues. (
- 2013
- Cocaine- and Amphetamine-regulated Transcript (CART) Protects Beta Cells against Glucotoxicity and Increases Cell Proliferation (
- AMPK alpha 1 Regulates Macrophage Skewing at the Time of Resolution of Inflammation during Skeletal Muscle Regeneration (
- Stretch-Sensitive Down-Regulation of the miR-144/451 Cluster in Vascular Smooth Muscle and Its Role in AMP-Activated Protein Kinase Signaling. (
- 2012
- The AMPK-related kinase SIK2 is regulated by cAMP via phosphorylation at Ser(358) in adipocytes (
- Adipocyte-Specific Protein Tyrosine Phosphatase 1B Deletion Increases Lipogenesis, Adipocyte Cell Size and Is a Minor Regulator of Glucose Homeostasis (
- cAMP-elevation mediated by β-adrenergic stimulation inhibits salt-inducible kinase (SIK) 3 activity in adipocytes. (
- Survival of pancreatic beta cells is partly controlled by a TCF7L2-p53-p53INP1-dependent pathway. (
- 2011
- Identification of new signaling components in the sensory epithelium of human saccule. (
- Regulation of AMP-activated protein kinase by LKB1 and CaMKK in adipocytes. (
- Rose hip exerts antidiabetic effects via a mechanism involving downregulation of the hepatic lipogenic program (
- Survival of rat pancreatic islets is partly controlled by a TCF7L2-p53-p53INP1 dependent pathway (
- 2010
- Rose hip exerts anti diabetic effects via a mechanism involving downregulation of the hepatic lipogenic program (
- 2009
- Regulation of AMP-activated protein kinase by cAMP in adipocytes: Roles for phosphodiesterases, protein kinase B, protein kinase A, Epac and lipolysis. (
- Protein kinase B activity is required for the effects of insulin on lipid metabolism in adipocytes. (
- 2008
- Use of Akt inhibitor and a drug-resistant mutant validates a critical role for protein kinase B/Akt in the insulin-dependent regulation of glucose and system A amino acid uptake (
- 2007
- Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase (
- 2006
- Regulation of the polarity kinases PAR-1/MARK by 14-3-3 interaction and phosphorylation (
- 2005
- 14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK (
- 2004
- Activity of LKB1 and AMPK-related kinases in skeletal muscle: effects of contraction, phenformin, and AICAR (
- Dimethylaminopurine inhibits metabolic effects of insulin in primary adipocytes. (
- LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1 (
- 2003
- Insulin Signalling and Regulation of Protein Kinase B in Adipocytes (
- 2002
- Protein phosphatase 2A is the main phosphatase involved in the regulation of protein kinase B in rat adipocytes. (
- Ser-474 is the major target of insulin-mediated phosphorylation of protein kinase B beta in primary rat adipocytes. (
- 1998
- Insulin-induced translocation of protein kinase B to the plasma membrane in rat adipocytes (