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2024
Mark Ligand-induced protein transition state stabilization switches the binding pathway from conformational selection to induced fit
Stenström, Olof ^LU ; Diehl, Carl ^LU ; Modig, Kristofer ^LU and Akke, Mikael ^LU (2024) In Proceedings of the National Academy of Sciences of the United States of America 121(14). p.2317747121-2317747121
- Contribution to journal › Article
Mark Modulating protein unfolding and refolding via the synergistic association of an anionic and a nonionic surfactant
Hjalte, Johanna ^LU ; Diehl, Carl ; Leung, Anna E. ; Poon, Jia Fei ^LU ; Porcar, Lionel ; Dalgliesh, Rob ; Sjögren, Helen ; Wahlgren, Marie ^LU and Sanchez-Fernandez, Adrian ^LU (2024) In Journal of Colloid and Interface Science 672. p.244-255
- Contribution to journal › Article
Mark Discovery of the Selective and Orally Available Galectin-1 Inhibitor GB1908 as a Potential Treatment for Lung Cancer
Zetterberg, Fredrik R. ; Peterson, Kristoffer ; Nilsson, Ulf J. ^LU ; Andréasson Dahlgren, Kajsa ; Diehl, Carl ; Hoyler, Ian ; Håkansson, Maria ; Khabut, Areej ^LU ; Kahl-Knutson, Barbro ^LU and Leffler, Hakon ^LU , et al. (2024) In Journal of Medicinal Chemistry 67(11). p.9374-9388
- Contribution to journal › Article
2023
Mark Discovery of Selective and Orally Available Galectin-1 Inhibitors
Zetterberg, Fredrik R ; Diehl, Carl ^LU ; Håkansson, Maria ^LU ; Kahl-Knutson, Barbro ^LU ; Leffler, Hakon ^LU ; Nilsson, Ulf J ^LU ; Peterson, Kristoffer ^LU ; Roper, James A and Slack, Robert J (2023) In Journal of Medicinal Chemistry 66(24). p.16980-16990
- Contribution to journal › Article
Mark Targeting Toll-like receptor-driven systemic inflammation by engineering an innate structural fold into drugs
Petruk, Ganna ^LU ; Puthia, Manoj ^LU ; Samsudin, Firdaus ; Petrlova, Jitka ^LU ; Olm, Franziska ^LU ; Mittendorfer, Margareta ^LU ; Hyllén, Snejana ^LU ; Edström, Dag ^LU ; Strömdahl, Ann-Charlotte ^LU and Diehl, Carl ^LU , et al. (2023) In Nature Communications 14. p.1-20
- Contribution to journal › Article
2021
Mark Mapping the energy landscape of protein-ligand binding via linear free energy relationships determined by protein NMR relaxation dispersion
Stenström, Olof ^LU ; Diehl, Carl ^LU ; Modig, Kristofer ^LU ; Nilsson, Ulf J. ^LU and Akke, Mikael ^LU (2021) In RSC Chemical Biology 2(1). p.259-265
- Contribution to journal › Article
Mark Benzimidazole–galactosides bind selectively to the Galectin-8 N-Terminal domain : Structure-based design and optimisation
Hassan, Mujtaba ^LU ; van Klaveren, Sjors ^LU ; Håkansson, Maria ^LU ; Diehl, Carl ^LU ; Kovačič, Rebeka ; Baussière, Floriane ; Sundin, Anders P. ^LU ; Dernovšek, Jaka ; Walse, Björn ^LU and Zetterberg, Fredrik , et al. (2021) In European Journal of Medicinal Chemistry 223.
- Contribution to journal › Article
2020
Mark An integrative toolbox to unlock the structure and dynamics of protein-surfactant complexes
Sanchez-Fernandez, Adrian ^LU ; Diehl, Carl ^LU ; Houston, Judith E. ; Leung, Anna E. ; Tellam, James P. ; Rogers, Sarah E. ; Prevost, Sylvain ; Ulvenlund, Stefan ^LU ; Sjögren, Helen ^LU and Wahlgren, Marie ^LU (2020) In Nanoscale Advances 2(9). p.4011-4023
- Contribution to journal › Article
2018
Mark Conformational Entropy of FK506 Binding to FKBP12 Determined by Nuclear Magnetic Resonance Relaxation and Molecular Dynamics Simulations
Solomentsev, Gleb ^LU ; Diehl, Carl ^LU and Akke, Mikael ^LU (2018) In Biochemistry 57(9). p.1451-1461
- Contribution to journal › Article
2016
Mark Structural analysis of a complex between small ubiquitin-like modifier 1 (SUMO1) and the ZZ domain of CREB-binding protein (CBP/p300) reveals a new interaction surface on SUMO
Diehl, Carl ^LU ; Akke, Mikael ^LU ; Bekker-Jensen, Simon ; Mailand, Niels ; Streicher, Werner and Wikström, Mats (2016) In Journal of Biological Chemistry 291(24). p.12658-12672
- Contribution to journal › Article

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