CNS Gene Therapy
1 – 77 of 77
- show: 250
- |
- sort: year (new to old)
Close
Embed this list
<iframe src=" "
width=" "
height=" "
allowtransparency="true"
frameborder="0">
</iframe>
- 2023
-
Mark
Visualizing Arc protein dynamics and localization in the mammalian brain using AAV-mediated in situ gene labeling
(
- Contribution to journal › Article
- 2022
-
Mark
Automated quantification of neuronal swellings in a preclinical rodent model of Parkinson's disease detects region-specific changes in pathology
(
- Contribution to journal › Article
-
Mark
Aβ/Amyloid Precursor Protein-Induced Hyperexcitability and Dysregulation of Homeostatic Synaptic Plasticity in Neuron Models of Alzheimer’s Disease
(
- Contribution to journal › Article
-
Mark
Inducing synthetic lethality for selective targeting of acute myeloid leukemia cells harboring STAG2 mutations
(
- Contribution to journal › Letter
-
Mark
Editorial : Gene therapy 2.0: Biotechnology for circuit engineering and complex therapeutic approaches
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Aβ/APP-induced hyperexcitability and dysregulation of homeostatic synaptic plasticity in models of Alzheimer’s disease
2022)(
- Working paper/Preprint › Preprint in preprint archive
- 2021
-
Mark
Exploring the miRNA profile of medium spiny neurons using retrograde transport in rats
2021) In Lund University, Faculty of Medicine Doctoral Dissertation Series(
- Thesis › Doctoral thesis (compilation)
- 2020
-
Mark
Development and Validation of CRISPR Activator Systems for Overexpression of CB1 Receptors in Neurons
(
- Contribution to journal › Article
-
Mark
Optimization of production and transgene expression of a retrogradely transported pseudotyped lentiviral vector
(
- Contribution to journal › Article
-
Mark
A comparison of AAV-vector production methods for gene therapy and preclinical assessment
(
- Contribution to journal › Article
- 2019
-
Mark
GDNF-mediated rescue of the nigrostriatal system depends on the degree of degeneration
(
- Contribution to journal › Article
-
Mark
Advances in stem cell research and therapeutic development
(
- Contribution to journal › Scientific review
-
Mark
The secreted virulence factor Nadase of Group A Streptococcus inhibits P2X7 receptor-mediated release of IL-1β
(
- Contribution to journal › Article
- 2018
-
Mark
Molecular barcoding of viral vectors enables mapping and optimization of mRNA trans-splicing
(
- Contribution to journal › Article
-
Mark
Striatonigral neurons divide into two distinct morphological-physiological phenotypes after chronic L-DOPA treatment in parkinsonian rats
(
- Contribution to journal › Article
-
Mark
Destabilizing Domains Enable Long-Term and Inert Regulation of GDNF Expression in the Brain
(
- Contribution to journal › Article
-
Mark
Rational design of a compact CRISPR-Cas9 activator for AAV-mediated delivery
2018)(
- Working paper/Preprint › Preprint in preprint archive
- 2016
-
Mark
Regulated Gene Therapy.
(
- Contribution to journal › Article
-
Mark
A regulatable AAV vector mediating GDNF biological effects at clinically-approved sub-antimicrobial doxycycline doses
(
- Contribution to journal › Article
-
Mark
Spatio-temporal activation of caspase-8 in myeloid cells upon ischemic stroke
(
- Contribution to journal › Article
- 2014
-
Mark
Gene Therapy for Parkinson’s Disease
(
- Chapter in Book/Report/Conference proceeding › Book chapter
- 2013
-
Mark
Specific genetic modifications in the CNS - Cell specific expression and gene specific regulation
(
- Thesis › Doctoral thesis (compilation)
-
Mark
Neuronal Differentiation and Extensive Migration of Human Neural Precursor Cells following Co-Culture with Rat Auditory Brainstem Slices
(
- Contribution to journal › Article
-
Mark
Visualization and genetic modification of resident brain microglia using lentiviral vectors regulated by microRNA-9.
(
- Contribution to journal › Article
-
Mark
Functional Neuroprotection and Efficient Regulation of GDNF Using Destabilizing Domains in a Rodent Model of Parkinson's Disease
(
- Contribution to journal › Article
-
Mark
FACS binding assay for analysing GDNF interactions.
(
- Contribution to journal › Article
- 2012
-
Mark
Destabilizing domains mediate reversible transgene expression in the brain.
(
- Contribution to journal › Article
-
Mark
Novel disease-specific promoters for use in gene therapy for Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
A Model of GDNF Gene Therapy in Mice with 6-Hydroxydopamine Lesions: Time Course of Neurorestorative Effects and ERK1/2 Activation
(
- Contribution to journal › Article
-
Mark
Difficult Questions and Ambivalent Answers on Genetic Testing
(
- Contribution to journal › Article
- 2011
-
Mark
Activity-dependent long-term plasticity of afferent synapses on grafted stem/progenitor cell-derived neurons.
(
- Contribution to journal › Article
-
Mark
Knock down of GAD67 protein levels normalizes neuronal activity in a rat model of Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Functional integration of grafted neural stem cell-derived dopaminergic neurons monitored by optogenetics in an in vitro Parkinson model.
(
- Contribution to journal › Article
- 2010
-
Mark
A General Chemical Method to Regulate Protein Stability in the Mammalian Central Nervous System
(
- Contribution to journal › Article
- 2009
-
Mark
Incorporating double copies of a chromatin insulator into lentiviral vectors results in less viral integrants
(
- Contribution to journal › Article
-
Mark
Neuron-specific RNA interference using lentiviral vectors
(
- Contribution to journal › Article
-
Mark
Identification of proteins involved in neural progenitor cell targeting of gliomas
(
- Contribution to journal › Article
-
Mark
Absence of striatal newborn neurons with mature phenotype following defined striatal and cortical excitotoxic brain injuries.
(
- Contribution to journal › Article
-
Mark
Optogenetic control of epileptiform activity.
(
- Contribution to journal › Article
-
Mark
Selective protein expression within the CNS using hybrid lentivirus.
(
- Contribution to journal › Article
- 2008
-
Mark
Applications of lentiviral vectors for biology and gene therapy of neurological disorders.
(
- Contribution to journal › Article
-
Mark
Reprogramming of neonatal SVZ progenitors by Islet-1 and Neurogenin-2.
(
- Contribution to journal › Article
- 2007
-
Mark
Progenitor cells in the postnatal central nervous system, characterization and genetic manipulation
2007)(
- Thesis › Doctoral thesis (compilation)
-
Mark
Instructive cross-talk between neural progenitor cells and gliomas.
(
- Contribution to journal › Article
-
Mark
Neural Progenitor Cells in malignancy and injury of the brain. A Trojan Horse fro gliomas?
2007)(
- Thesis › Doctoral thesis (compilation)
- 2006
-
Mark
Combretastatin A-1 phosphate potentiates the antitumor activity of carboplatin and paclitaxel in a severe combined immunodeficiency disease (SCID) mouse model of human ovarian carcinoma.
(
- Contribution to journal › Article
-
Mark
Retrovirally delivered Islet-1 increases recruitment of Ng2 expressing cells from the postnatal SVZ into the striatum.
(
- Contribution to journal › Article
-
Mark
Efficient transduction of neurons using Ross River glycoprotein-pseudotyped lentiviral vectors.
(
- Contribution to journal › Article
-
Mark
Chemokine-directed migration of tumor-inhibitory neural progenitor cells towards an intracranially growing glioma.
(
- Contribution to journal › Article
-
Mark
Lentiviral Vectors for Use in the Central Nervous System.
(
- Contribution to journal › Scientific review
-
Mark
Evidence for disease-regulated transgene expression in the brain with use of lentiviral vectors.
(
- Contribution to journal › Article
- 2005
-
Mark
Ex vivo gene delivery of GDNF using primary astrocytes transduced with a lentiviral vector provides neuroprotection in a rat model of Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Inhibition of chromatin condensation prevents transgene silencing in a neural progenitor cell line transplanted to the rat brain.
(
- Contribution to journal › Article
-
Mark
Astrocytes as Cellular Vehicles in Ex Vivo Gene Therapy Studies to the Rat Brain
2005)(
- Thesis › Doctoral thesis (compilation)
- 2004
-
Mark
Regionalization and fate specification in neurospheres: the role of Olig2 and Pax6
(
- Contribution to journal › Article
-
Mark
Migratory capacity of the cell line RN33B and the host glial cell response after subretinal transplantation to normal adult rats.
(
- Contribution to journal › Article
-
Mark
Dynamics of transgene expression in a neural stem cell line transduced with lentiviral vectors incorporating the cHS4 insulator.
(
- Contribution to journal › Article
-
Mark
Induction of neurites by the regulatory domains of PKCdelta and epsilon is counteracted by PKC catalytic activity and by the RhoA pathway.
(
- Contribution to journal › Article
-
Mark
Lesion-dependent regulation of transgene expression in the rat brain using a human glial fibrillary acidic protein-lentiviral vector.
(
- Contribution to journal › Article
-
Mark
Neural progenitor cell lines inhibit rat tumor growth in vivo.
(
- Contribution to journal › Article
-
Mark
Survival and long distance migration of brain-derived precursor cells transplanted to adult rat retina
(
- Contribution to journal › Article
- 2003
-
Mark
Elevated GDNF levels following viral vector-mediated gene transfer can increase neuronal death after stroke in rats.
(
- Contribution to journal › Article
-
Mark
Cells of the nervous system
(
- Contribution to journal › Article
- 2002
-
Mark
Activation of silenced transgene expression in neural precursor cell lines by inhibitors of histone deacetytation
(
- Contribution to journal › Article
-
Mark
Subretinal Transplantation of Brain-derived Precursor Cells to Young RCS Rats Promotes Photoreceptor Cell Survival( small star, filled).
(
- Contribution to journal › Article
-
Mark
Transplantation of human neural progenitor cells into the neonatal rat brain: extensive migration and differentiation with long-distance axonal projections.
(
- Contribution to journal › Article
-
Mark
Von Willebrand's disease caused by compound heterozygosity for a substitution mutation (T1156M) in the D3 domain of the von Willebrand factor and a stop mutation (Q2470X).
(
- Contribution to journal › Article
-
Mark
Long-term survival and glial differentiation of the brain-derived precursor cell line RN33B after subretinal transplantation to adult normal rats
(
- Contribution to journal › Article
- 2001
-
Mark
Long-term survival, integration and differentiation of brain-derived precursor cells after subretinal transplantation to adult normal rats
(
- Contribution to journal › Article
-
Mark
Partial protection of photoreceptor cells in RCS rats following lentiviral gene transfer of glial cell line-derived neurotrophic factor (GDNF)
(
- Contribution to journal › Article
-
Mark
Integration and differentiation of brain-derived precursor cells transplanted to developing normal and mutant rhodopsin transgenic rats
(
- Contribution to journal › Article
-
Mark
Direct delivery of leptin to the hypothalamus using recombinant adeno-associated virus vectors results in increased therapeutic efficacy
(
- Contribution to journal › Article
-
Mark
Neural transplantation: restoring complex circuitry in the striatum
(
- Contribution to journal › Article
-
Mark
Survival and integration of the brain-derived precursor cell line RN33B subretinally transplanted to the RCS rat
(
- Contribution to journal › Article
- 2000
-
Mark
Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model
(
- Contribution to journal › Article
-
Mark
In vivo protection of nigral dopamine neurons by lentiviral gene transfer of the novel GDNF-family member neublastin/artemin
(
- Contribution to journal › Article
- 1996
-
Mark
Use of neural progenitor cell lines and astrocytes for transplantation and gene transfer to the CNS.
1996)(
- Thesis › Doctoral thesis (compilation)