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- 2023
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Mark
Functional and molecular profiling of hematopoietic stem cells during regeneration
(
- Contribution to journal › Article
- 2022
-
Mark
Single-cell transcriptional profiling informs efficient reprogramming of human somatic cells to cross-presenting dendritic cells
(
- Contribution to journal › Article
-
Mark
BMPR1a Is Required for the Optimal TGFβ1-Dependent CD207+ Langerhans Cell Differentiation and Limits Skin Inflammation through CD11c+ Cells
(
- Contribution to journal › Article
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Mark
Schlafen2 is a regulator of quiescence in adult murine hematopoietic stem cells
(
- Contribution to journal › Article
-
Mark
Successful gene therapy of Diamond-Blackfan anemia in a mouse model and human CD34+ cord blood hematopoietic stem cells using a clinically applicable lentiviral vector
(
- Contribution to journal › Article
- 2021
-
Mark
Correction of pathology in mice displaying Gaucher disease type 1 by a clinically-applicable lentiviral vector
(
- Contribution to journal › Article
-
Mark
Bone marrow transplantation without myeloablative conditioning in a mouse model for Diamond-Blackfan anemia corrects the disease phenotype
(
- Contribution to journal › Article
-
Mark
BMP signaling is required for postnatal murine hematopoietic stem cell self-renewal
(
- Contribution to journal › Article
- 2020
-
Mark
S100A6 is a critical regulator of hematopoietic stem cells.
2020) In Leukemia(
- Contribution to journal › Article
- 2018
-
Mark
Tipping clonal hematopoiesis into transformation
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1
(
- Contribution to journal › Article
- 2017
-
Mark
Lentiviral Vectors with Cellular Promoters Correct Anemia and Lethal Bone Marrow Failure in a Mouse Model for Diamond-Blackfan Anemia
(
- Contribution to journal › Article
-
Mark
Roscoe Owen Brady, MD : Remembrances of co-investigators and colleagues
(
- Contribution to journal › Article
-
Mark
The stem cell regulator PEDF is dispensable for maintenance and function of hematopoietic stem cells
(
- Contribution to journal › Article
-
Mark
Signaling via Smad2 and Smad3 is dispensable for adult murine hematopoietic stem cell function in vivo
2017) In Experimental Hematology(
- Contribution to journal › Article
- 2016
-
Mark
A network including TGFβ/Smad4, Gata2 and p57 regulates proliferation of mouse hematopoietic progenitor cells.
(
- Contribution to journal › Article
-
Mark
Glucosylated cholesterol in mammalian cells and tissues: formation and degradation by multiple cellular β-glucosidases.
(
- Contribution to journal › Article
-
Mark
Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma
(
- Contribution to journal › Article
- 2015
-
Mark
TGIF1 is a negative regulator of MLL-rearranged acute myeloid leukemia.
(
- Contribution to journal › Article
-
Mark
Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond-Blackfan anaemia.
(
- Contribution to journal › Article
-
Mark
Disruption of the 5S RNP-Mdm2 interaction significantly improves the erythroid defect in a mouse model for Diamond-Blackfan anemia.
(
- Contribution to journal › Article
-
Mark
TGF-β signaling in the control of hematopoietic stem cells.
(
- Contribution to journal › Article
-
Mark
Lentiviral gene therapy using cellular promoters cures type 1 Gaucher disease in mice.
(
- Contribution to journal › Article
-
Mark
Inhibition of UDP-glucosylceramide synthase in mice prevents Gaucher disease-associated B-cell malignancy
(
- Contribution to journal › Article
- 2014
-
Mark
Dppa5 improves hematopoietic stem cell activity by reducing endoplasmic reticulum stress.
(
- Contribution to journal › Article
-
Mark
The SKI proto-oncogene enhances the in vivo repopulation of hematopoietic stem cells and causes myeloproliferative disease
(
- Contribution to journal › Article
-
Mark
Gene therapy cures the anemia and lethal bone marrow failure in mouse model for RPS19-deficient Diamond-Blackfan anemia.
(
- Contribution to journal › Article
- 2013
-
Mark
The Tetraspanin CD9 Affords High-Purity Capture of All Murine Hematopoietic Stem Cells
(
- Contribution to journal › Article
-
Mark
Functional and genetic characterization of the non-lysosomal glucosylceramidase 2 as a modifier for Gaucher disease
(
- Contribution to journal › Article
-
Mark
B cell lymphoma and myeloma in murine Gaucher's disease
(
- Contribution to journal › Article
-
Mark
Increased glucocerebrosidase (GBA) 2 activity in GBA1 deficient mice brains and in Gaucher leucocytes
(
- Contribution to journal › Article
- 2012
-
Mark
SPARC is dispensable for murine hematopoiesis, despite its suspected pathophysiological role in 5q- myelodysplastic syndrome.
(
- Contribution to journal › Article
-
Mark
Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions
(
- Contribution to journal › Article
-
Mark
Hematopoietic stem cells are regulated by Cripto, as an intermediary of HIF-1α in the hypoxic bone marrow niche.
(
- Contribution to journal › Article
-
Mark
Angptl4 maintains in vivo repopulation capacity of CD34(+) human cord blood cells.
(
- Contribution to journal › Article
-
Mark
Common signaling networks characterize leukemia-initiating cells in acute myeloid leukemia.
(
- Contribution to journal › Article
-
Mark
Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia.
(
- Contribution to journal › Article
-
Mark
Human hematopoietic stem/progenitor cells overexpressing Smad4 exhibit impaired reconstitution potential in vivo.
(
- Contribution to journal › Article
- 2011
-
Mark
The role of Smad signaling in hematopoiesis and translational hematology.
(
- Contribution to journal › Article
-
Mark
Stem cell self-renewal: lessons from bone marrow, gut and iPS toward clinical applications
(
- Contribution to journal › Scientific review
-
Mark
Stress hematopoiesis requires Erg
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche
(
- Contribution to journal › Article
-
Mark
High levels of the adhesion molecule CD44 on leukemic cells generate acute myeloid leukemia relapse after withdrawal of the initial transforming event.
(
- Contribution to journal › Article
-
Mark
SMAD4 binds HOXA9 in the cytoplasm and protects primitive hematopoietic cells against nuclear activation by HOXA9 and leukemia transformation.
(
- Contribution to journal › Article
-
Mark
Cripto Regulates Hematopoietic Stem Cells as a Hypoxic-Niche-Related Factor through Cell Surface Receptor GRP78.
(
- Contribution to journal › Article
-
Mark
Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia.
(
- Contribution to journal › Article
- 2010
-
Mark
Development of Novel Therapies in Murine Models for Gaucher Disease
2010) 7th Annual Conference of the British-Society-for-Gene-Therapy In Human Gene Therapy 21(4). p.490-491(
- Contribution to journal › Published meeting abstract
-
Mark
Chronic RPS19 Deficiency Leads to Bone Marrow Failure In a Mouse Model for Diamond Blackfan Anemia
(
- Contribution to journal › Published meeting abstract
-
Mark
PIM1 kinase is destabilized by ribosomal stress causing inhibition of cell cycle progression
(
- Contribution to journal › Article
-
Mark
Altered expression and distribution of cathepsins in neuronopathic forms of Gaucher disease and in other sphingolipidoses
(
- Contribution to journal › Article
-
Mark
Successful Treatment of Metachromatic Leukodystrophy Using Bone Marrow Transplantation of HoxB4 Overexpressing Cells
(
- Contribution to journal › Article
-
Mark
Cripto Selectively Expands a Distinct Population of Hematopoietic Stem Cells Expressing the Cell Surface Receptor GRP78 and Strongly Induces An Immature Phenotype In Vivo After Ex Vivo Culture
(
- Contribution to journal › Published meeting abstract
-
Mark
High Levels of the Adhesion Molecule CD44 on Leukemic Cells Generate Acute Myeloid Leukemia Relapse After Withdrawal of the Initial Transforming Event
(
- Contribution to journal › Published meeting abstract
-
Mark
SMAD4 Sequestrates HOXA9 to Protect Hematopoietic Stem Cells Against Leukemia Transformation
(
- Contribution to journal › Published meeting abstract
-
Mark
Cripto Selectively Expands a Distinct Population Of Hematopoietic Stem Cells Expressing Cell Surface Receptor GRP78
2010) 39th Annual Scientific Meeting of the ISEH - Society-for-Hematology-and-Stem-Cells In Experimental Hematology 38(9). p.038-038(
- Contribution to journal › Published meeting abstract
-
Mark
Canonical BMP signaling is dispensable for hematopoietic stem cell function in both adult and fetal liver hematopoiesis, but essential to preserve colon architecture.
(
- Contribution to journal › Article
- 2009
-
Mark
In an inducible model of acute myeloid leukemia, secondary hits are required to generate a leukemia relapse after removal of the initial transforming event
2009) 38th Annual Scientific Meeting of the ISEH-Society-for-Hematology-and-Stem-Cells In Experimental Hematology 37(9). p.16-16(
- Contribution to journal › Published meeting abstract
-
Mark
A Novel Mouse Model for RPS19-Deficient Diamond-Blackfan Anemia Locates the Erythroid Defect at CFU-E/Proerythroblast Transition
(
- Contribution to journal › Published meeting abstract
-
Mark
Development of Novel Therapies in Murine Models for Gaucher Disease
(
- Chapter in Book/Report/Conference proceeding › Paper in conference proceeding
-
Mark
No evidence for activation of the unfolded protein response in neuronopathic models of Gaucher disease
(
- Contribution to journal › Article
-
Mark
Fetal Gene Therapy for Acute Neuronopathic Gaucher Disease
2009) 12th Annual Meeting of the American Society of Gene Therapy In Molecular Therapy 17. p.357-357(
- Contribution to journal › Published meeting abstract
-
Mark
Poor vessel formation in embryos from knock-in mice expressing ALK5 with L45 loop mutation defective in Smad activation
(
- Contribution to journal › Article
-
Mark
Lipocalin 2 negatively controls erythroid and macrophage lineages via megalin as its receptor
2009) 38th Annual Scientific Meeting of the ISEH-Society-for-Hematology-and-Stem-Cells In Experimental Hematology 37(9). p.80-81(
- Contribution to journal › Published meeting abstract
-
Mark
Successful Low-Risk Hematopoietic Cell Therapy in a Mouse Model of Type 1 Gaucher Disease
(
- Contribution to journal › Article
-
Mark
SMAD4 as a therapeutic target in hoxa9-related leukemia
2009) 38th Annual Scientific Meeting of the ISEH-Society-for-Hematology-and-Stem-Cells In Experimental Hematology 37(9). p.44-45(
- Contribution to journal › Published meeting abstract
-
Mark
Complex and context dependent regulation of hematopoiesis by TGF-beta superfamily signaling.
(
- Contribution to journal › Scientific review
-
Mark
Is TGF-beta a stemness regulator?
(
- Contribution to journal › Article
- 2008
-
Mark
Diagnosing and treating Diamond Blackfan anaemia: results of an international clinical consensus conference
(
- Contribution to journal › Scientific review
-
Mark
Hematopoietic stem cell responsiveness to exogenous signals is limited by Caspase-3
(
- Contribution to journal › Article
-
Mark
A critical role for Smad4 in the self-renewal of hematopoietic stem cells
2008) 4th Conference on Stem Cell Gene Therapy In Blood Cells, Molecules, and Diseases 40(2). p.271-271(
- Contribution to journal › Published meeting abstract
-
Mark
Brain area-specific effect of TGF-beta signaling on Wnt-dependent neural stem cell expansion
(
- Contribution to journal › Article
-
Mark
Clonal mar-king and genetic manipulation of AGM HSCs
2008) 37th Annual Scientific Meeting featuring the 6th International Neonatal Hematology and Immunology Meeting In Experimental Hematology 36(7, Supplement 1). p.69-69(
- Contribution to journal › Published meeting abstract
-
Mark
Smad4 as a Therapeutic Target in Nup98-HoxA9-Induced Leukemia.
(
- Contribution to journal › Published meeting abstract
-
Mark
Enforced expression of c-Ski in adult murine hematopoiesis promotes myeloid - Differentiation, revealing an important role for c-Ski in governing hematopoietic cell fate options
2008) 37th Annual Scientific Meeting featuring the 6th International Neonatal Hematology and Immunology Meeting In Experimental Hematology 36(7, Supplement 1). p.29-29(
- Contribution to journal › Published meeting abstract
-
Mark
A HOXA10-inducible mouse model demonstrates an important role of the initial transforming event in the maintenance of the leukemia
2008) 37th Annual Scientific Meeting featuring the 6th International Neonatal Hematology and Immunology Meeting In Experimental Hematology 36(7, Supplement 1). p.4-5(
- Contribution to journal › Published meeting abstract
-
Mark
Therapeutic effects of bone marrow transplantation for metachromatic leukodystrophy using HOXB4 over-expressing cells
2008) The 13th Annual Meeting 2007 Japan Society of Gene Therapy In Journal of Gene Medicine 10(4). p.476-477(
- Contribution to journal › Published meeting abstract
-
Mark
RPS19 Deficiency Leads to Reduced Proliferation and Increased Apoptosis but Does Not Affect Terminal Erythroid Differentiation in a Cell Line Model of Diamond-Blackfan Anemia
(
- Contribution to journal › Article
-
Mark
Stem cell regulation and host defense: the logic and the paradox.
(
- Contribution to journal › Article
-
Mark
Signaling pathways governing stem cell fate.
(
- Contribution to journal › Scientific review
-
Mark
Gene therapy of Diamond Blackfan anemia CD34(+) cells leads to improved erythroid development and engraftment following transplantation.
(
- Contribution to journal › Article
-
Mark
Successful low-risk hematopoietic cell therapy in a mouse model of type 1 Gaucher disease.
2008) p.1189-1190(
- Contribution to conference › Poster
- 2007
-
Mark
Connecting ribosomes with bone marrow failure
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Diamond-Blackfan anemia: erythropoiesis lost in translation.
(
- Contribution to journal › Scientific review
-
Mark
HOXA10 is a critical regulator for hematopoietic stem cells and erythroid/megakaryocyte development.
(
- Contribution to journal › Article
-
Mark
Hematopoietic stem cell targeted neonatal gene therapy reverses lethally progressive osteopetrosis in oc/oc mice.
(
- Contribution to journal › Article
-
Mark
Female mice are more susceptible to developing inflammatory disorders due to impaired transforming growth factor beta signaling in salivary glands
(
- Contribution to journal › Article
-
Mark
Hoxa9/hoxb3/hoxb4 compound null mice display severe hematopoietic defects
(
- Contribution to journal › Article
-
Mark
Adenoviral vectors for transient gene expression in human primitive hematopoietic cells: Applications and prospects.
(
- Contribution to journal › Scientific review
-
Mark
TGF-beta receptor I conditional knockout mice develop spontaneous squamous cell carcinoma
(
- Contribution to journal › Article
-
Mark
Endoglin is not critical for hematopoietic stem cell engraftment and reconstitution but regulates adult erythroid development
(
- Contribution to journal › Article
-
Mark
Neuron-specific TGF-beta signaling deficiency results in retinal detachment and cataracts in mice
(
- Contribution to journal › Article
-
Mark
Smad4 is critical for self-renewal of hematopoietic stem cells.
(
- Contribution to journal › Article
-
Mark
Human RPS19, the gene mutated in Diamond Blackfan anemia, encodes a ribosomal protein required for the maturation of 40S ribosomal subunits.
(
- Contribution to journal › Article
-
Mark
Murine models of acute neuronopathic Gaucher disease
(
- Contribution to journal › Article
- 2006
-
Mark
Erythropoiesis in the Rps19 disrupted mouse: Analysis of erythropoietin response and biochemical markers for Diamond-Blackfan anemia
(
- Contribution to journal › Article
-
Mark
Smad7 promotes self-renewal of hematopoietic stem cells in vivo.
(
- Contribution to journal › Article
-
Mark
Smad5 is dispensable for adult murine hematopoiesis.
(
- Contribution to journal › Article
-
Mark
Neonatal hematopoietic stem cell transplantation cures oc/oc mice from osteopetrosis.
(
- Contribution to journal › Article
-
Mark
Epithelial and ectomesenchymal role of the type I TGF-beta receptor ALK5 during facial morphogenesis and palatal fusion
(
- Contribution to journal › Article
-
Mark
Effective cell and gene therapy in a murine model of Gaucher disease.
(
- Contribution to journal › Article