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- 2024
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A genomic mutational constraint map using variation in 76,156 human genomes
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- Contribution to journal › Article
- 2022
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Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes
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- Contribution to journal › Article
- 2021
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Glucose-Dependent Insulinotropic Peptide in the High-Normal Range Is Associated With Increased Carotid Intima-Media Thickness
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- Contribution to journal › Article
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Mark
Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes
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- Contribution to journal › Article
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Adult-onset diabetes in Middle Eastern immigrants to Sweden : Novel subgroups and diabetic complications—The All New Diabetes in Scania cohort diabetic complications and ethnicity
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- Contribution to journal › Article
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Elevated circulating follistatin associates with an increased risk of type 2 diabetes
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- Contribution to journal › Article
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Reduced expression of OXPHOS and DNA damage genes is linked to protection from microvascular complications in long-term type 1 diabetes : the PROLONG study
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- Contribution to journal › Article
- 2020
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Liver nucleotide biosynthesis is linked to protection from vascular complications in individuals with long-term type 1 diabetes
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- Contribution to journal › Article
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The effect of LRRK2 loss-of-function variants in humans
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- Contribution to journal › Article
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Glucose-dependent insulinotropic peptide and risk of cardiovascular events and mortality : a prospective study
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- Contribution to journal › Article
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Genome-wide association analysis of type 2 diabetes in the EPIC-InterAct study
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- Contribution to journal › Article
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Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals
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- Contribution to journal › Article
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Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes
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- Contribution to journal › Article
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Mark
Increased Plasma Soluble Interleukin-2 Receptor Alpha Levels in Patients With Long-Term Type 1 Diabetes With Vascular Complications Associated With IL2RA and PTPN2 Gene Polymorphisms
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- Contribution to journal › Article
- 2019
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Mark
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls
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- Contribution to journal › Article
- 2018
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Mark
Lessons learned from the 1-hour post-load glucose level during OGTT : Current screening recommendations for dysglycaemia should be revised
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- Contribution to journal › Article
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Petition to replace current OGTT criteria for diagnosing prediabetes with the 1-hour post-load plasma glucose ≥ 155 mg/dl (8.6 mmol/L)
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- Contribution to journal › Scientific review
- 2017
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Genetic determinants of circulating GIP and GLP-1 concentrations
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- Contribution to journal › Article
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Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls
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- Contribution to journal › Article
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A low-frequency inactivating AKT2 variant enriched in the finnish population is associated with fasting insulin levels and type 2 diabetes risk
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- Contribution to journal › Article
- 2016
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Mark
Glucose-Dependent Insulinotropic Polypeptide (GIP) Stimulates Osteopontin Expression in the Vasculature via Endothelin-1 and CREB.
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- Contribution to journal › Article
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Mark
Atrial Natriuretic Peptide in the high normal range is associated with lower prevalence of insulin resistance.
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- Contribution to journal › Article
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Mark
The genetic architecture of type 2 diabetes
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- Contribution to journal › Article
- 2015
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Mark
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.
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- Contribution to journal › Article
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Modelling of OGTT curve identifies 1 h plasma glucose level as a strong predictor of incident type 2 diabetes: results from two prospective cohorts
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- Contribution to journal › Article
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Mark
Dubbelt så hög risk för diabetes typ 2 hos svenskar födda i Irak
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- Contribution to specialist publication or newspaper › Specialist publication article
- 2014
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Mark
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
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- Contribution to journal › Article
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Mark
A Central Role for GRB10 in Regulation of Islet Function in Man.
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- Contribution to journal › Article
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Mark
Gene-Lifestyle Interaction and Type 2 Diabetes: The EPIC InterAct Case-Cohort Study.
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- Contribution to journal › Article
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Mark
Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independently of obesity.
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- Contribution to journal › Article
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Mark
Type 2 diabetes susceptibility gene variants predispose to adult-onset autoimmune diabetes
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- Contribution to journal › Article
- 2013
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Mark
Age at Menopause, Reproductive Life Span, and Type 2 Diabetes Risk
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- Contribution to journal › Article
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Mark
Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes
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- Contribution to journal › Article
- 2012
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Mark
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
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- Contribution to journal › Article
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Mark
Physical activity reduces the risk of incident type 2 diabetes in general and in abdominally lean and obese men and women: the EPIC-InterAct Study
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- Contribution to journal › Article
- 2011
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Mark
Pleiotropic Effects of GIP on Islet Function Involve Osteopontin
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- Contribution to journal › Article
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Mark
FTO, Type 2 Diabetes, and Weight Gain Throughout Adult Life A Meta-Analysis of 41,504 Subjects From the Scandinavian HUNT, MDC, and MPP Studies
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- Contribution to journal › Article
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Mark
Power in the Phenotypic Extremes: A Simulation Study of Power in Discovery and Replication of Rare Variants
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- Contribution to journal › Article
- 2010
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Mark
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
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- Contribution to journal › Article
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Mark
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
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- Contribution to journal › Article
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Mark
Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes
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- Contribution to journal › Article
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Mark
Plasma copeptin and the risk of diabetes mellitus.
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- Contribution to journal › Article
- 2009
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Mark
A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion.
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- Contribution to journal › Article
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Mark
Previously Associated Type 2 Diabetes Variants May Interact With Physical Activity to Modify the Risk of Impaired Glucose Regulation and Type 2 Diabetes A Study of 16,003 Swedish Adults
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- Contribution to journal › Article
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Mark
Genome-wide association study identifies eight loci associated with blood pressure
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- Contribution to journal › Article
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Mark
Assessing the effect of interaction between an FTO variant (rs9939609) and physical activity on obesity in 15,925 Swedish and 2,511 Finnish adults.
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- Contribution to journal › Article
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Mark
Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion.
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- Contribution to journal › Article
- 2008
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Mark
Is there a unifying genetic factor predisposing to the metabolic syndrome?
2008) 44th EASD Annual Meeting of the European Association for the Study of Diabetes In Diabetologia 51(S1). p.32-33(
- Contribution to journal › Published meeting abstract
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Mark
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans
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- Contribution to journal › Article
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Mark
Common variants in maturity-onset diabetes of the young genes and future risk of type 2 diabetes
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- Contribution to journal › Article
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Mark
Clinical risk factors, DNA variants, and the development of type 2 diabetes.
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- Contribution to journal › Article
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Mark
The search for putative unifying genetic factors for components of the metabolic syndrome.
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- Contribution to journal › Article
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Mark
Polymorphism associated with cholesterol and risk of cardiovascular events
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- Contribution to journal › Article
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Mark
Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus
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- Contribution to journal › Article
- 2007
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Mark
Association testing of common variants in the insulin receptor substrate-1 gene (IRS1) with type 2 diabetes
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- Contribution to journal › Article
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Mark
Polymorphisms in the gene encoding the voltage-dependent Ca(2+) channel Ca (V)2.3 (CACNA1E) are associated with type 2 diabetes and impaired insulin secretion
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- Contribution to journal › Article
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Mark
Genetic and epigenetic factors are associated with expression of respiratory chain component NDUFB6 in human skeletal muscle
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- Contribution to journal › Article
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Mark
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
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- Contribution to journal › Article
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Mark
Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes.
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- Contribution to journal › Article
- 2006
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Mark
Polymorphism in the MHC2TA gene is associated with features of the metabolic syndrome and cardiovascular mortality.
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- Contribution to journal › Article
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Mark
Common variants in HNF-1 alpha and risk of type 2 diabetes.
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- Contribution to journal › Article