Neurobiology
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- 2010
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Mark
Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors.
(
- Contribution to journal › Article
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Mark
Characterisation of behavioural and neurodegenerative changes induced by intranigral 6-hydroxydopamine lesions in a mouse model of Parkinson's disease.
(
- Contribution to journal › Article
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Mark
Preface
(
- Chapter in Book/Report/Conference proceeding › Foreword/Postscript
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Mark
Recent advances in Parkinson's disease : basic research. Preface
(
- Contribution to journal › Article
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Mark
Alterations of matrix metalloproteinases in the healthy elderly with increased risk of prodromal Alzheimer's disease
(
- Contribution to journal › Article
- 2009
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Mark
Differential Infectivity Following Basal Ganglia Administration of Differing AAV Serotypes in Nonhuman Primates
2009) 16th Annual Meeting of the American-Society-for-Neural-Therapy-and-Repair In Cell Transplantation 18(2). p.212-213(
- Contribution to journal › Published meeting abstract
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Mark
Serotonin neuron-dependent and -independent reduction of dyskinesia by 5-HT(1A) and 5-HT(1B) receptor agonists in the rat Parkinson model.
(
- Contribution to journal › Article
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Mark
Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells
(
- Contribution to journal › Article
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Mark
Systemic lipopolysaccharide plus MPTP as a model of dopamine loss and gait instability in C57Bl/6J mice
(
- Contribution to journal › Article
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Mark
Nurr1 Is Required for Maintenance of Maturing and Adult Midbrain Dopamine Neurons
(
- Contribution to journal › Article
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Mark
Identification of dopamine neuron progenitors in the embryonic midbrain and stem cell cultures - Studies on the role of neuronal subtype and differentiation state for cell replacemen in a rodent model of Parkinson's disease
(
- Thesis › Doctoral thesis (compilation)
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Mark
Optimization of continuous in vivo DOPA production and studies on ectopic DA synthesis using rAAV5 vectors in Parkinsonian rats
(
- Contribution to journal › Article
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Mark
Transgenic reporter mice as tools for studies of transplantability and connectivity of dopamine neuron precursors in fetal tissue grafts
(
- Contribution to journal › Scientific review
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Mark
Identification of Transplantable Dopamine Neuron Precursors at Different Stages of Midbrain Neurogenesis.
(
- Contribution to journal › Article
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Mark
Organization of the human embryonic ventral mesencephalon.
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- Contribution to journal › Article
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Mark
Reconstruction of the nigrostriatal dopamine pathway in the adult mouse brain.
(
- Contribution to journal › Article
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Mark
Impact of grafted serotonin and dopamine neurons on development of L-DOPA-induced dyskinesias in parkinsonian rats is determined by the extent of dopamine neuron degeneration.
(
- Contribution to journal › Article
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Mark
Gene therapy for dopamine replacement in Parkinson's disease.
(
- Contribution to journal › Article
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Mark
Dopamine neuron precursors within the developing human mesencephalon show radial glial characteristics.
(
- Contribution to journal › Article
- 2008
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Mark
The GTP-binding protein Rhes modulates dopamine signalling in striatal medium spiny neurons
(
- Contribution to journal › Article
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Mark
In vivo gene delivery to proliferating cells in the striatum generated in response to a 6-hydroxydopamine lesion of the nigro-striatal dopamine pathway
(
- Contribution to journal › Article
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Mark
Combined 5-HT1A and 5-HT1B receptor agonists for the treatment of L-DOPA-induced dyskinesia.
(
- Contribution to journal › Article
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Mark
Embryonic dopaminergic precursors can be isolated at different states of differentiation and function upon grafting into an animal model of Parkinson's disease
2008) 17th Biennial Meeting of the International-Society-for-Developmental-Neuroscience In International Journal of Developmental Neuroscience 26(8). p.887-888(
- Contribution to journal › Published meeting abstract
-
Mark
Asn1421Lys mutation in the glycoprotein Ib binding domain impairs - ristocetin and botrocetin - mediated binding of von Willebrand factor to platelets
2008) XXVIIIth International Congress of the World Federation of Hemophilia, 2008 In Haemophilia 14(s2). p.116-116(
- Contribution to journal › Published meeting abstract
-
Mark
Generation of cells for cell-replacement therapy: Specification of neural precursors in vivo and in neural stem cell cultures
(
- Thesis › Doctoral thesis (compilation)
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Mark
Gene therapy for Parkinson's disease
2008) 19th Helsinki Drug Research 2008 In European Journal of Pharmaceutical Sciences 34(1, Suppl. 1). p.14-14(
- Contribution to journal › Published meeting abstract
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Mark
Myeloid and lymphoid contribution to non-haematopoietic lineages through irradiation-induced heterotypic cell fusion.
(
- Contribution to journal › Article
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Mark
N1421K mutation in the glycoprotein Ib binding domain impairs ristocetin- and botrocetin-mediated binding of von Willebrand factor to platelets.
(
- Contribution to journal › Article
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Mark
Non-dopaminergic neurons in ventral mesencephalic transplants make widespread axonal connections in the host brain.
(
- Contribution to journal › Article
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Mark
Serotonin-dopamine interaction in the induction and maintenance of L-DOPA-induced dyskinesias
(
- Contribution to journal › Article
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Mark
Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation.
(
- Contribution to journal › Article
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Mark
Unilateral axonal or terminal injection of 6-hydroxydopamine causes rapid-onset nigrostriatal degeneration and contralateral motor impairments in the rat.
(
- Contribution to journal › Article
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Mark
Involvement of the serotonin system in L-dopa-induced dyskinesias
(
- Contribution to journal › Article
- 2007
-
Mark
Brain area, age and viral vector-specific glial cell-line-derived neurotrophic factor expression and transport in rat.
(
- Contribution to journal › Article
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Mark
Generation of human cortical neurons from a new immortal fetal neural stem cell line.
(
- Contribution to journal › Article
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Mark
Seizure Suppression by GDNF Gene Therapy in Animal Models of Epilepsy.
(
- Contribution to journal › Article
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Mark
Ngn2 and Nurr1 act in synergy to induce midbrain dopaminergic neurons from expanded neural stem and progenitor cells.
(
- Contribution to journal › Article
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Mark
The functional impact of the intrastriatal dopamine neuron grafts in parkinsonian rats is reduced with advancing disease
(
- Contribution to journal › Article
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Mark
In vitro characterization of a human neural progenitor cell coexpressing SSEA4 and CD133.
(
- Contribution to journal › Article
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Mark
Dopamine neuron systems in the brain: an update
(
- Contribution to journal › Scientific review
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Mark
Communication breakdown - synaptic dysfunction in Huntington's disease.
2007)(
- Thesis › Doctoral thesis (compilation)
-
Mark
Serotonin neuron transplants exacerbate L-DOPA-induced dyskinesias in a rat model of Parkinson's disease
(
- Contribution to journal › Article
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Mark
Early specification of dopaminergic phenotype during ES cell differentiation
(
- Contribution to journal › Article
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Mark
Fifty years of dopamine research.
(
- Contribution to journal › Letter
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Mark
Dopamine released from 5-HT terminals is the cause of L-DOPA-induced dyskinesia in parkinsonian rats.
(
- Contribution to journal › Article
- 2006
-
Mark
Efficient transduction of neurons using Ross River glycoprotein-pseudotyped lentiviral vectors.
(
- Contribution to journal › Article
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Mark
Retrovirally delivered Islet-1 increases recruitment of Ng2 expressing cells from the postnatal SVZ into the striatum.
(
- Contribution to journal › Article
-
Mark
Continuous exposure to glial cell line-derived neurotrophic factor to mature dopaminergic transplants impairs the graft's ability to improve spontaneous motor behavior in parkinsonian rats.
(
- Contribution to journal › Article
-
Mark
Reversal of neurochemical changes and pain-related behavior in a model of neuropathic pain using modified lentiviral vectors expressing GDNF
(
- Contribution to journal › Article
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Mark
Improved high-capacity adenoviral vectors for high-level neuron-restricted gene transfer to the CNS
(
- Contribution to journal › Article
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Mark
Development of the mesencephalic dopaminergic neuron system is compromised in the absence of neurogenin 2.
(
- Contribution to journal › Article
-
Mark
Neurogenin2 identifies a transplantable dopamine neuron precursor in the developing ventral mesencephalon.
(
- Contribution to journal › Article
-
Mark
Graft placement and uneven pattern of reinnervation in the striatum is important for development of graft-induced dyskinesia.
(
- Contribution to journal › Article
-
Mark
Intracellular signaling and cellular plasticity in a rat model of L-DOPA-induced dyskinesia
2006)(
- Thesis › Doctoral thesis (compilation)
-
Mark
Strengths and limitations of the neurosphere culture system.
(
- Contribution to journal › Article
-
Mark
Transplantation of human embryonic stem cell-derived cells to a rat model of Parkinson's disease: Effect of in vitro differentiation on graft survival and teratoma formation
(
- Contribution to journal › Article
- 2005
-
Mark
Reversal of dyskinesias in an animal model of Parkinson's disease by continuous L-DOPA delivery using rAAV vectors.
(
- Contribution to journal › Article
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Mark
Inhibition of chromatin condensation prevents transgene silencing in a neural progenitor cell line transplanted to the rat brain.
(
- Contribution to journal › Article
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Mark
Gene marking of human neural stem/precursor cells using green fluorescent proteins
(
- Contribution to journal › Article
-
Mark
Histological analysis of fetal dopamine cell suspension grafts in two patients with Parkinson's disease gives promising results
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
In vivo labeling of neuroblasts in the subventricular zone of rats.
(
- Contribution to journal › Article
-
Mark
Isolation and characterization of neural precursor cells from the Sox1-GFP reporter mouse.
(
- Contribution to journal › Article
-
Mark
Parkinson's disease: Viral vector delivery of parkin generates model results in rats.
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Functional properties and synaptic integration of genetically labelled dopaminergic neurons in intrastriatal grafts.
(
- Contribution to journal › Article
-
Mark
Increased fiber outgrowth from xeno-transplanted human embryonic dopaminergic neurons with co-implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor.
(
- Contribution to journal › Article
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Mark
Ex vivo gene delivery of GDNF using primary astrocytes transduced with a lentiviral vector provides neuroprotection in a rat model of Parkinson's disease.
(
- Contribution to journal › Article
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Mark
Cell therapy for Parkinson's disease: problems and prospects.
(
- Contribution to journal › Article
-
Mark
Pharmacological validation of a mouse model of l-DOPA-induced dyskinesia.
(
- Contribution to journal › Article
-
Mark
Factors affecting the clinical outcome after neural transplantation in Parkinson's disease
(
- Contribution to journal › Article
-
Mark
Continuous low-level glial cell line-derived neurotrophic factor delivery using recombinant adeno-associated viral vectors provides neuroprotection and induces behavioral recovery in a primate model of Parkinson's disease
(
- Contribution to journal › Article
-
Mark
Development of lentiviral vectors for CNS gene transfer
2005)(
- Thesis › Doctoral thesis (compilation)
-
Mark
Generation of midbrain dopaminergic neurons in vivo and in vitro: the role of Neurogenin2
2005) In Lund University Faculty of Medicine Doctoral Dissertation Series(
- Thesis › Doctoral thesis (compilation)
-
Mark
Viral Vector Mediated Overexpression of Human alpha-Synuclein in the Nigrostriatal Dopaminergic Neurons: A New Model for Parkinson's Disease.
(
- Contribution to journal › Scientific review
-
Mark
Identification of dopaminergic neurons of nigral and ventral tegmental area subtypes in grafts of fetal ventral mesencephalon based on cell morphology, protein expression, and efferent projections.
(
- Contribution to journal › Article
-
Mark
Cell transplantation in Parkinson's disease: how can we make it work?
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Enriched environment increases neural stem/progenitor cell proliferation and neurogenesis in the subventricular zone of stroke-lesioned adult rats
(
- Contribution to journal › Article
-
Mark
Mechanisms of Transgene Silencing in Neural Cells -Implications for Ex Vivo Gene Therapy to the Brain
2005)(
- Thesis › Doctoral thesis (compilation)
- 2004
-
Mark
Lesion-dependent regulation of transgene expression in the rat brain using a human glial fibrillary acidic protein-lentiviral vector.
(
- Contribution to journal › Article
-
Mark
Transcriptome analysis in a rat model of L-DOPA-induced dyskinesia
(
- Contribution to journal › Article
-
Mark
Dissociation between short-term increased graft survival and long-term functional improvements in Parkinsonian rats overexpressing glial cell line-derived neurotrophic factor.
(
- Contribution to journal › Article
-
Mark
A model of L-DOPA-induced dyskinesia in 6-hydroxydopamine lesioned mice: relation to motor and cellular parameters of nigrostriatal function.
(
- Contribution to journal › Article
-
Mark
Dynamics of transgene expression in a neural stem cell line transduced with lentiviral vectors incorporating the cHS4 insulator.
(
- Contribution to journal › Article
-
Mark
Overexpression of glial cell line-derived neurotrophic factor using a lentiviral vector induces time- and dose-dependent downregulation of tyrosine hydroxylase in the intact nigrostriatal dopamine system.
(
- Contribution to journal › Article
-
Mark
Regulated delivery of glial cell line-derived neurotrophic factor into rat striatum, using a tetracycline-dependent lentiviral vector.
(
- Contribution to journal › Article
-
Mark
Localized striatal delivery of GDNF as a treatment for Parkinson disease.
(
- Contribution to journal › Article
-
Mark
Special Issue Stem Cells - Preface
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Cell Therapy in Parkinson's Disease.
(
- Contribution to journal › Article
-
Mark
Striatal neuron differentiation from neurosphere-expanded progenitors depends on Gsh2 expression.
2004) In The Journal of Neuroscience : the official journal of the Society for Neuroscience 24(31). p.6958-6967(
- Contribution to journal › Article
-
Mark
Postischemic housing in an enriched environment influences hippocampal progenitor cell differentiation after focal cortical ischemia
(
- Chapter in Book/Report/Conference proceeding › Paper in conference proceeding
-
Mark
GDNF gene delivery in an animal model of Parkinson's disease. Long-term effects on intact, injured and transplanted dopamine neurons using lentiviral gene transfer
2004)(
- Thesis › Doctoral thesis (compilation)
-
Mark
Cell replacement therapy : helping the brain to repair itself
(
- Contribution to journal › Debate/Note/Editorial
- 2003
-
Mark
Anterograde delivery of brain-derived neurotrophic factor to striatum via nigral transduction of recombinant adeno-associated virus increases neuronal death but promotes neurogenic response following stroke.
(
- Contribution to journal › Article
-
Mark
A transplantation study of expanded human embryonic forebrain precursors: evidence for selection of a specific progenitor population.
(
- Contribution to journal › Article
-
Mark
Neural transplantation for the treatment of Parkinson's disease
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Long-term striatal overexpression of GDNF selectively downregulates tyrosine hydroxylase in the intact nigrostriatal dopamine system.
(
- Contribution to journal › Article
-
Mark
Nigrostriatal {alpha}-synucleinopathy induced by viral vector-mediated overexpression of human {alpha}-synuclein: A new primate model of Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Neuronal differentiation following transplantation of expanded mouse neurosphere cultures derived from different embryonic forebrain regions.
(
- Contribution to journal › Article
-
Mark
Regulation of neuropeptide mRNA expression in the basal ganglia by intrastriatal and intranigral transplants in the rat Parkinson model.
(
- Contribution to journal › Article
-
Mark
Phenotypic and molecular identity of cells in the adult subventricular zone. in vivo and after expansion in vitro.
(
- Contribution to journal › Article
-
Mark
The differentiation potential of precursor cells from the mouse lateral ganglionic eminence is restricted by in vitro expansion.
(
- Contribution to journal › Article