Division of Molecular Medicine and Gene Therapy
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- 2021
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Mark
BCAT1 decreases the sensitivity of cancer cells to cisplatin by regulating mTOR-mediated autophagy via branched-chain amino acid metabolism
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- Contribution to journal › Article
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Sister chromatid cohesion defects are associated with chromosomal copy number heterogeneity in high hyperdiploid childhood acute lymphoblastic leukemia
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- Contribution to journal › Article
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Decreased PGC1beta expression results in disrupted human erythroid differentiation, impaired hemoglobinization and cell cycle exit
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- Contribution to journal › Article
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Mark
Elucidating regulators of red blood cell development in health and disease
2021) In Lund University, Faculty of Medicine Doctoral Dissertation Series(
- Thesis › Doctoral thesis (compilation)
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Mark
Disruption of a GATA2-TAL1-ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells
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- Contribution to journal › Article
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Genome-wide association study on 13,167 individuals identifies regulators of hematopoietic stem and progenitor cell levels in human blood
2021)(
- Working paper/Preprint › Preprint in preprint archive
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The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition
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- Contribution to journal › Article
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Reprogramming Stars #1 : Genome Programming through the Cell Cycle - An Interview with Dr. Tomomi Tsubouchi
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- Contribution to journal › Debate/Note/Editorial
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Reprogramming, the Journal
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- Contribution to journal › Debate/Note/Editorial
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Uncoupling key determinants of hematopoietic stem cell engraftment through cell-specific and temporally controlled recipient conditioning
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- Contribution to journal › Article
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Bone marrow transplantation without myeloablative conditioning in a mouse model for Diamond-Blackfan anemia corrects the disease phenotype
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- Contribution to journal › Article
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Organ sparing total marrow irradiation compared to total body irradiation prior to allogeneic stem cell transplantation
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- Contribution to journal › Article
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In vitro differentiation of human pluripotent stem cells into the B lineage using OP9-MS5 co-culture
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- Contribution to journal › Article
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Gene therapy for infantile malignant osteopetrosis : review of pre-clinical research and proof-of-concept for phenotypic reversal
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- Contribution to journal › Scientific review
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Hypoxia-induced alpha-globin expression in syncytiotrophoblasts mimics the pattern observed in preeclamptic placentas
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- Contribution to journal › Article
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Ontogenic shifts in cellular fate are linked to proteotype changes in lineage-biased hematopoietic progenitor cells
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- Contribution to journal › Article
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Mark
Stem cell aging and wound healing
2021) p.53-60(
- Chapter in Book/Report/Conference proceeding › Book chapter
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Mark
Reprogramming Stars #4 : A Reprogramming Approach for Parkinson's Disease-An Interview with Dr. Malin Parmar
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- Contribution to journal › Debate/Note/Editorial
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Reprogramming Stars #3 : Mechanisms of iPSC Reprogramming-An Interview with Dr. Keisuke Kaji
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- Contribution to journal › Debate/Note/Editorial
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Mark
Compositions for reprogramming into dendritic cells type 2 competent for antigen presentation, methods and uses thereof
2021) WO2021105234(
- Patent › Patent
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Mark
Compositions for reprogramming cells into plasmacytoid dendritic cells or interferon producing cells, methods and uses thereof
2021) WO2021069672(
- Patent › Patent
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Mark
Human Primary Airway Basal Cells Display a Continuum of Molecular Phases from Health to Disease in Chronic Obstructive Pulmonary Disease
(
- Contribution to journal › Article
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Mark
Generating Dendritic Cells by Direct Cell Reprogramming. Merging cellular reprogramming with immunology towards the development of novel cancer immunotherapies.
2021) In Lund University, Faculty of Medicine Doctoral Dissertation Series(
- Thesis › Doctoral thesis (compilation)
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Mark
Activation of endogenous retroviruses during brain development causes an inflammatory response
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- Contribution to journal › Article
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Mark
Identification of potential chemical compounds enhancing generation of enucleated cells from immortalized human erythroid cell lines
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- Contribution to journal › Article
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Mark
BMP signaling is required for postnatal murine hematopoietic stem cell self-renewal
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- Contribution to journal › Article
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Cell Fate Reprogramming in the Era of Cancer Immunotherapy
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- Contribution to journal › Scientific review
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Yippee like 4 (Ypel4) is essential for normal mouse red blood cell membrane integrity
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- Contribution to journal › Article
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Mark
Reprogramming Stars #2 : Reprogramming towards Neural Lineages - An Interview with Dr. Henrik Ahlenius
(
- Contribution to journal › Debate/Note/Editorial
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Mark
The active component of ginseng, ginsenoside Rb1, improves erythropoiesis in models of Diamond–Blackfan anemia by targeting Nemo-like kinase
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- Contribution to journal › Article
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Mark
Glutamine metabolism regulates endothelial to hematopoietic transition and hematopoietic lineage specification
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- Contribution to journal › Article
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Restoring the immunogenicity of cancer cells with dendritic cell reprogramming
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- Contribution to journal › Published meeting abstract
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GATA2 at the mitosis-to-G1 transition is critical for definitive hematopoiesis
2021) 2021 Virtual Annual Scientific Meeting of the ISEH - International Society for Experimental Hematology: ISEH 50th Annual Meeting In Experimental Hematology 100(Suppl). p.35-35(
- Contribution to journal › Published meeting abstract
- 2020
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Mark
Early growth response 1 regulates hematopoietic support and proliferation in human primary bone marrow stromal cells
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- Contribution to journal › Article
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Mark
Combined lentiviral- and RNA-mediated CRISPR/Cas9 delivery for efficient and traceable gene editing in human hematopoietic stem and progenitor cells
(
- Contribution to journal › Article
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Mark
Enhancing mitochondrial function in vivo rescues MDS-like anemia induced by pRb deficiency
(
- Contribution to journal › Article
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Mark
Identification of regulators of hematopoietic stem and progenitor cells in vivo in humans using population genetics
2020) European Human Genetics Virtual Conference(
- Contribution to conference › Abstract
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Mark
Så skapar nanoteknik nya vägar till stamcellers inre
2020) In Onkologi i Sverige : den oberoende tidningen för svensk cancervård(
- Contribution to specialist publication or newspaper › Specialist publication article
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Mark
Prospective isolation of radiation induced erythroid stress progenitors reveals unique transcriptomic and epigenetic signatures enabling increased erythroid output
(
- Contribution to journal › Article
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Mark
Metformin-induced suppression of Nemo-like kinase improves erythropoiesis in preclinical models of Diamond–Blackfan anemia through induction of miR-26a
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- Contribution to journal › Article
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Mark
Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase
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- Contribution to journal › Article
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Mark
Mononuclear phagocyte regulation by the transcription factor Blimp-1 in health and disease
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- Contribution to journal › Scientific review
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Mark
The Role of α1-Microglobulin (A1M) in Erythropoiesis and Erythrocyte Homeostasis-Therapeutic Opportunities in Hemolytic Conditions
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- Contribution to journal › Scientific review
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Mark
Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Disease 2019
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- Contribution to journal › Scientific review
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Mark
Calmodulin inhibitors improve erythropoiesis in Diamond-Blackfan anemia
(
- Contribution to journal › Article
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Mark
Lysine-specific demethylase 1A (LSD1) restricts ex vivo propagation of human HSCs and is a target of UM171
(
- Contribution to journal › Article
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Mark
Efficient and nontoxic biomolecule delivery to primary human hematopoietic stem cells using nanostraws
2020) In Proceedings of the National Academy of Sciences of the United States of America 117(35). p.21267-21273(
- Contribution to journal › Article
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Mark
S100A6 is a critical regulator of hematopoietic stem cells.
2020) In Leukemia(
- Contribution to journal › Article
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Mark
CXCR4 Signaling Has a CXCL12-Independent Essential Role in Murine MLL-AF9-Driven Acute Myeloid Leukemia
(
- Contribution to journal › Article
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Mark
Generation of gene-corrected functional osteoclasts from osteopetrotic induced pluripotent stem cells
(
- Contribution to journal › Article