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2024
Mark Development and Characterization of a High-Affinity Selective Galectin-3 Mouse Tool Compound in Mouse Models of Cancer
Peterson, Kristoffer ^LU ; Nilsson, Ulf J. ^LU ; Gravelle, Lise ; Holyer, Ian ; Jansson, Karl ; Kahl-Knutson, Barbro ^LU ; Leffler, Hakon ^LU ; MacKinnon, Alison C. ; Roper, James A. and Slack, Robert J. , et al. (2024) In Journal of Medicinal Chemistry 67(24). p.21905-21915
- Contribution to journal › Article
Mark Discovery of the Selective and Orally Available Galectin-1 Inhibitor GB1908 as a Potential Treatment for Lung Cancer
Zetterberg, Fredrik R. ; Peterson, Kristoffer ; Nilsson, Ulf J. ^LU ; Andréasson Dahlgren, Kajsa ; Diehl, Carl ; Hoyler, Ian ; Håkansson, Maria ; Khabut, Areej ^LU ; Kahl-Knutson, Barbro ^LU and Leffler, Hakon ^LU , et al. (2024) In Journal of Medicinal Chemistry 67(11). p.9374-9388
- Contribution to journal › Article
2023
Mark Fluorescently Guided Optical Photothermal Infrared Microspectroscopy for Protein-Specific Bioimaging at Subcellular Level
Prater, Craig ; Bai, Yeran ; Konings, Sabine C ^LU ; Martinsson, Isak ^LU ; Swaminathan, Vinay S ^LU ; Nordenfelt, Pontus ^LU ; Gouras, Gunnar ^LU ; Borondics, Ferenc and Klementieva, Oxana ^LU (2023) In Journal of Medicinal Chemistry 66(4). p.2542-2549
- Contribution to journal › Article
Mark Strong Binding of C-Glycosylic1,2-Thiodisaccharides to Galectin-3─Enthalpy-Driven Affinity Enhancement by Water-Mediated Hydrogen Bonds
Lázár, László ; Tsagkarakou, Anastasia S ; Stravodimos, George ; Kontopidis, George ; Leffler, Hakon ^LU ; Nilsson, Ulf J ^LU ; Somsák, László and Leonidas, Demetres D (2023) In Journal of Medicinal Chemistry 66(17). p.12420-12431
- Contribution to journal › Article
Mark Ligand Sulfur Oxidation State Progressively Alters Galectin-3-Ligand Complex Conformations To Induce Affinity-Influencing Hydrogen Bonds
Mahanti, Mukul ^LU ; Pal, Kumar Bhaskar ; Kumar, Rohit ^LU ; Schulze, Markus ; Leffler, Hakon ^LU ; Logan, Derek T ^LU and Nilsson, Ulf J ^LU (2023) In Journal of Medicinal Chemistry 66(21). p.14716-14723
- Contribution to journal › Article
Mark Discovery of Selective and Orally Available Galectin-1 Inhibitors
Zetterberg, Fredrik R ; Diehl, Carl ^LU ; Håkansson, Maria ^LU ; Kahl-Knutson, Barbro ^LU ; Leffler, Hakon ^LU ; Nilsson, Ulf J ^LU ; Peterson, Kristoffer ^LU ; Roper, James A and Slack, Robert J (2023) In Journal of Medicinal Chemistry 66(24). p.16980-16990
- Contribution to journal › Article
2018
Mark Elucidation of Hydrogen Bonding Patterns in Ligand-Free, Lactose- and Glycerol-Bound Galectin-3C by Neutron Crystallography to Guide Drug Design
Manzoni, Francesco ^LU ; Wallerstein, Johan ^LU ; Schrader, Tobias E ; Ostermann, Andreas ; Coates, Leighton ; Akke, Mikael ^LU ; Blakeley, Matthew P ; Oksanen, Esko ^LU and Logan, Derek T ^LU (2018) In Journal of Medicinal Chemistry 61(10). p.4412-4420
- Contribution to journal › Article
2017
Mark Fragment-Based Discovery and Optimization of Enzyme Inhibitors by Docking of Commercial Chemical Space
Rudling, Axel ; Gustafsson, Robert ; Almlöf, Ingrid ; Homan, Evert ; Scobie, Martin ; Warpman Berglund, Ulrika ; Helleday, Thomas ; Stenmark, Pål ^LU and Carlsson, Jens (2017) In Journal of Medicinal Chemistry 60(19). p.8160-8169
- Contribution to journal › Article
Mark Class II Phosphoinositide 3-Kinases as Novel Drug Targets
Falasca, Marco ; Hamilton, Justin R ; Selvadurai, Maria ; Sundaram, Krithika ; Adamska, Aleksandra ^LU and Thompson, Philip E (2017) In Journal of Medicinal Chemistry 60(1). p.47-65
- Contribution to journal › Scientific review
Mark Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors
Thorsell, Ann-Gerd ; Ekblad, Torun ; Karlberg, Tobias ^LU ; Löw, Mirjam ; Pinto, Ana Filipa ; Trésaugues, Lionel ; Moche, Martin ; Cohen, Michael S and Schüler, Herwig ^LU (2017) In Journal of Medicinal Chemistry 60(4). p.1262-1271
- Contribution to journal › Article

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