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- 2024
-
Mark
Development and Characterization of a High-Affinity Selective Galectin-3 Mouse Tool Compound in Mouse Models of Cancer
Peterson, Kristoffer LU ; Nilsson, Ulf J. LU
; Gravelle, Lise
; Holyer, Ian
; Jansson, Karl
; Kahl-Knutson, Barbro
LU
; Leffler, Hakon
LU
; MacKinnon, Alison C.
; Roper, James A.
and Slack, Robert J.
, et al.
(2024)
In Journal of Medicinal Chemistry
67(24).
p.21905-21915
- Contribution to journal › Article
-
Mark
Discovery of the Selective and Orally Available Galectin-1 Inhibitor GB1908 as a Potential Treatment for Lung Cancer
Zetterberg, Fredrik R. ; Peterson, Kristoffer ; Nilsson, Ulf J. LU
; Andréasson Dahlgren, Kajsa
; Diehl, Carl
; Hoyler, Ian
; Håkansson, Maria
; Khabut, Areej
LU
; Kahl-Knutson, Barbro
LU
and Leffler, Hakon
LU
, et al.
(2024)
In Journal of Medicinal Chemistry
67(11).
p.9374-9388
- Contribution to journal › Article
- 2023
-
Mark
Discovery of Selective and Orally Available Galectin-1 Inhibitors
Zetterberg, Fredrik R ; Diehl, Carl LU ; Håkansson, Maria LU ; Kahl-Knutson, Barbro LU ; Leffler, Hakon LU ; Nilsson, Ulf J LU
; Peterson, Kristoffer
LU
; Roper, James A
and Slack, Robert J
(2023)
In Journal of Medicinal Chemistry
66(24).
p.16980-16990
- Contribution to journal › Article
-
Mark
Fluorescently Guided Optical Photothermal Infrared Microspectroscopy for Protein-Specific Bioimaging at Subcellular Level
Prater, Craig ; Bai, Yeran ; Konings, Sabine C LU
; Martinsson, Isak
LU
; Swaminathan, Vinay S
LU
; Nordenfelt, Pontus
LU
; Gouras, Gunnar
LU
; Borondics, Ferenc
and Klementieva, Oxana
LU
(2023)
In Journal of Medicinal Chemistry
66(4).
p.2542-2549
- Contribution to journal › Article
-
Mark
Strong Binding of C-Glycosylic1,2-Thiodisaccharides to Galectin-3─Enthalpy-Driven Affinity Enhancement by Water-Mediated Hydrogen Bonds
Lázár, László ; Tsagkarakou, Anastasia S ; Stravodimos, George ; Kontopidis, George ; Leffler, Hakon LU ; Nilsson, Ulf J LU
; Somsák, László
and Leonidas, Demetres D
(2023)
In Journal of Medicinal Chemistry
66(17).
p.12420-12431
- Contribution to journal › Article
-
Mark
Ligand Sulfur Oxidation State Progressively Alters Galectin-3-Ligand Complex Conformations To Induce Affinity-Influencing Hydrogen Bonds
Mahanti, Mukul LU ; Pal, Kumar Bhaskar ; Kumar, Rohit LU ; Schulze, Markus ; Leffler, Hakon LU ; Logan, Derek T LU
and Nilsson, Ulf J
LU
(2023)
In Journal of Medicinal Chemistry
66(21).
p.14716-14723
- Contribution to journal › Article
- 2018
-
Mark
Elucidation of Hydrogen Bonding Patterns in Ligand-Free, Lactose- and Glycerol-Bound Galectin-3C by Neutron Crystallography to Guide Drug Design
Manzoni, Francesco LU ; Wallerstein, Johan LU
; Schrader, Tobias E
; Ostermann, Andreas
; Coates, Leighton
; Akke, Mikael
LU
; Blakeley, Matthew P
; Oksanen, Esko
LU
and Logan, Derek T
LU
(2018)
In Journal of Medicinal Chemistry
61(10).
p.4412-4420
- Contribution to journal › Article
- 2017
-
Mark
Fragment-Based Discovery and Optimization of Enzyme Inhibitors by Docking of Commercial Chemical Space
Rudling, Axel ; Gustafsson, Robert ; Almlöf, Ingrid ; Homan, Evert ; Scobie, Martin ; Warpman Berglund, Ulrika ; Helleday, Thomas ; Stenmark, Pål LU
and Carlsson, Jens
(2017)
In Journal of Medicinal Chemistry
60(19).
p.8160-8169
- Contribution to journal › Article
-
Mark
Class II Phosphoinositide 3-Kinases as Novel Drug Targets
- Contribution to journal › Scientific review
-
Mark
Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors
Thorsell, Ann-Gerd ; Ekblad, Torun ; Karlberg, Tobias LU ; Löw, Mirjam ; Pinto, Ana Filipa ; Trésaugues, Lionel ; Moche, Martin ; Cohen, Michael S and Schüler, Herwig LU
(2017)
In Journal of Medicinal Chemistry
60(4).
p.1262-1271
- Contribution to journal › Article