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- 2024
-
Mark
The AAV-α-Synuclein Model of Parkinson's Disease : An Update
2024) In Journal of Parkinson's Disease(
- Contribution to journal › Scientific review
- 2023
-
Mark
Athymic Nude Rat Brain Atlas
2023)(
- Book/Report › Book
-
Mark
Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson's disease, STEM-PD
(
- Contribution to journal › Article
-
Mark
Protocol for optical clearing and imaging of fluorescently labeled ex vivo rat brain slices
(
- Contribution to journal › Article
- 2022
-
Mark
A Combined α-Synuclein/Fibril (SynFib) Model of Parkinson-Like Synucleinopathy Targeting the Nigrostriatal Dopamine System
(
- Contribution to journal › Scientific review
-
Mark
Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human fetal midbrain
(
- Contribution to journal › Article
- 2021
-
Mark
Grafts Derived from an α-Synuclein Triplication Patient Mediate Functional Recovery but Develop Disease-Associated Pathology in the 6-OHDA Model of Parkinson's Disease
(
- Contribution to journal › Article
-
Mark
Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids
(
- Contribution to journal › Article
- 2020
-
Mark
Light sheet fluorescence microscopy of optically cleared brains for studying the glymphatic system
(
- Contribution to journal › Article
-
Mark
Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model of PD
2020) In Proceedings of the National Academy of Sciences of the United States of America 117(26). p.15209-15220(
- Contribution to journal › Article
- 2019
-
Mark
hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson's Disease
(
- Contribution to journal › Article
- 2018
-
Mark
Chemogenetic modulation of cholinergic interneurons reveals their regulating role on the direct and indirect output pathways from the striatum
(
- Contribution to journal › Article
-
Mark
Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats
(
- Contribution to journal › Article
- 2017
-
Mark
Modeling Parkinson’s disease pathology by combination of fibril seeds and α-synuclein overexpression in the rat brain
2017) In Proceedings of the National Academy of Sciences of the United States of America 114(39). p.8284-8293(
- Contribution to journal › Article
- 2016
-
Mark
DREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor
(
- Contribution to journal › Article
-
Mark
Extensive graft-derived dopaminergic innervation is maintained 24 years after transplantation in the degenerating parkinsonian brain.
2016) In Proceedings of the National Academy of Sciences of the United States of America 113(23). p.6544-6549(
- Contribution to journal › Article
-
Mark
α-Synuclein induced toxicity in brain stem serotonin neurons mediated by an AAV vector driven by the tryptophan hydroxylase promoter
(
- Contribution to journal › Article
- 2015
-
Mark
Nurr1 and Retinoid X Receptor Ligands Stimulate Ret Signaling in Dopamine Neurons and Can Alleviate α-Synuclein Disrupted Gene Expression.
(
- Contribution to journal › Article
- 2014
-
Mark
Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson's Disease.
(
- Contribution to journal › Article
-
Mark
microRNA-125 distinguishes developmentally generated and adult-born olfactory bulb interneurons.
(
- Contribution to journal › Article
- 2013
-
Mark
TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity.
(
- Contribution to journal › Article
- 2012
-
Mark
Progressive neurodegenerative and behavioural changes induced by AAV-mediated overexpression of α-synuclein in midbrain dopamine neurons.
(
- Contribution to journal › Article
-
Mark
Alpha-Synuclein Cell-to-Cell Transfer and Seeding in Grafted Dopaminergic Neurons In Vivo.
(
- Contribution to journal › Article
-
Mark
Impaired neurotransmission caused by overexpression of α-synuclein in nigral dopamine neurons.
(
- Contribution to journal › Article
-
Mark
α-Synuclein-Induced Down-Regulation of Nurr1 Disrupts GDNF Signaling in Nigral Dopamine Neurons.
(
- Contribution to journal › Article
-
Mark
Comparison of the behavioural and histological characteristics of the 6-OHDA and alpha-synuclein rat models of Parkinson's disease
(
- Contribution to journal › Article
- 2011
-
Mark
GDNF fails to exert neuroprotection in a rat {alpha}-synuclein model of Parkinson's disease.
(
- Contribution to journal › Article
- 2010
-
Mark
Adeno-associated viral vector serotypes 1 and 5 targeted to the neonatal rat and pig striatum induce widespread transgene expression in the forebrain
(
- Contribution to journal › Article
-
Mark
Characterisation of Behavioural and Neurodegenerative Changes Induced by Intranigral 6-Hydroxydopamine Lesions in a Mouse Model of Parkinson's Disease
(
- Contribution to journal › Published meeting abstract
-
Mark
Characterisation of behavioural and neurodegenerative changes induced by intranigral 6-hydroxydopamine lesions in a mouse model of Parkinson's disease.
(
- Contribution to journal › Article
- 2009
-
Mark
Impact of grafted serotonin and dopamine neurons on development of L-DOPA-induced dyskinesias in parkinsonian rats is determined by the extent of dopamine neuron degeneration.
(
- Contribution to journal › Article
-
Mark
Nurr1 Is Required for Maintenance of Maturing and Adult Midbrain Dopamine Neurons
(
- Contribution to journal › Article
- 2006
-
Mark
Enriched environment after focal cortical ischemia enhances the generation of astroglia and NG2 positive polydendrocytes in adult rat neocortex
(
- Contribution to journal › Article
- 2005
-
Mark
Enriched environment increases neural stem/progenitor cell proliferation and neurogenesis in the subventricular zone of stroke-lesioned adult rats
(
- Contribution to journal › Article
- 2004
-
Mark
Postischemic housing in an enriched environment influences hippocampal progenitor cell differentiation after focal cortical ischemia
(
- Chapter in Book/Report/Conference proceeding › Paper in conference proceeding
- 2002
-
Mark
Effects of cortical ischemia and postischemic environmental enrichment on hippocampal cell genesis and differentiation in the adult rat
(
- Contribution to journal › Article
-
Mark
Environmental influences on functional outcome after a cortical infarct in the rat.
(
- Contribution to journal › Article
- 2001
-
Mark
Neuronal and fibre organization in neocortical grafts placed in post-ischaemic adult rat brain: a three-dimensional confocal microscopy study
(
- Contribution to journal › Article
- 2000
-
Mark
Environmental influence on brain-derived neurotrophic factor messenger RNA expression after middle cerebral artery occlusion in spontaneously hypertensive rats
(
- Contribution to journal › Article
-
Mark
Expression of zinc-positive cells and terminals in fetal neocortical homografts to adult rat depends on lesion type and rearing conditions
(
- Contribution to journal › Article
- 1999
-
Mark
Environmental enrichment alters nerve growth factor-induced gene A and glucocorticoid receptor messenger RNA expression after middle cerebral artery occlusion in rats
(
- Contribution to journal › Article
-
Mark
Environmental influence on gene expression and recovery from cerebral ischemia
(
- Contribution to journal › Article
-
Mark
Are neuronal markers and neocortical graft-host interface influenced by housing conditions in rats with cortical infarct cavity?
(
- Contribution to journal › Article
- 1997
-
Mark
Neural grafting to experimental neocortical infarcts improves behavioral outcome and reduces thalamic atrophy in rats housed in enriched but not in standard environments
(
- Contribution to journal › Article
- 1995
-
Mark
Influence of an enriched environment and cortical grafting on functional outcome in brain infarcts of adult rats
(
- Contribution to journal › Article
- 1993
-
Mark
Brain capillary density and cerebral blood flow after occlusion of the middle cerebral artery in normotensive Wistar-Kyoto rats and spontaneously hypertensive rats
(
- Contribution to journal › Article