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- 2024
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Mark
Integrative Kinase Activity Profiling and Phosphoproteomics of rd10 Mouse Retina during cGMP-Dependent Retinal Degeneration
(
- Contribution to journal › Article
- 2023
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Mark
The photoreceptor protective cGMP-analog Rp-8-Br-PET-cGMPS interacts with cGMP-interactors PKGI, PDE1, PDE6, and PKAI in the degenerating mouse retina
(
- Contribution to journal › Article
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Mark
Pyruvate Kinase 2, an Energy Metabolism Related Enzyme, May Have a Neuroprotective Function in Retinal Degeneration
(
- Contribution to journal › Article
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Mark
A Potential Neuroprotective Role for Pyruvate Kinase 2 in Retinal Degeneration
(
- Chapter in Book/Report/Conference proceeding › Book chapter
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Mark
The Phosphoproteome of the Rd1 Mouse Retina, a Model of Inherited Photoreceptor Degeneration, Changes after Protein Kinase G Inhibition
(
- Contribution to journal › Article
- 2022
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Mark
Enhanced cGMP Interactor Rap Guanine Exchange Factor 4 (EPAC2) Expression and Activity in Degenerating Photoreceptors: : A Neuroprotective Response?
(
- Contribution to journal › Article
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Mark
A Potential Role of Cyclic Dependent Kinase 1 (CDK1) in Late Stage of Retinal Degeneration
(
- Contribution to journal › Article
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Mark
The stereospecific interaction sites and target specificity of cGMP analogs in mouse cortex
(
- Contribution to journal › Article
- 2021
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Mark
cGMP-PKG dependent transcriptome in normal and degenerating retinas: Novel insights into the retinitis pigmentosa pathology
(
- Contribution to journal › Article
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Mark
The cGMP system in normal and degenerating mouse neuroretina : New proteins with cGMP interaction potential identified by a proteomics approach
(
- Contribution to journal › Article
- 2020
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Mark
Cellular mechanisms of hereditary photoreceptor degeneration – Focus on cGMP
(
- Contribution to journal › Scientific review
- 2019
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Mark
Drug delivery to retinal photoreceptors
(
- Contribution to journal › Scientific review
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Mark
Modulation of Calcium Overload and Calpain Activity
(
- Contribution to journal › Article
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Mark
Modulation of cGMP-signalling to Prevent Retinal Degeneration
(
- Contribution to journal › Article
- 2018
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Mark
Electrospun nerve guide conduits have the potential to bridge peripheral nerve injuries in vivo.
(
- Contribution to journal › Article
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Mark
Combination of cGMP analogue and drug delivery system provides functional protection in hereditary retinal degeneration
2018) In Proceedings of the National Academy of Sciences of the United States of America 115(13). p.2997-3006(
- Contribution to journal › Article
- 2016
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Mark
Increased Plasma cGMP in a Family With Autosomal Recessive Retinitis Pigmentosa Due to Homozygous Mutations in the PDE6A Gene
(
- Contribution to journal › Article
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Mark
Efficacy of PARP inhibition in Pde6a mutant mouse models for retinitis pigmentosa depends on the quality and composition of individual human mutations
(
- Contribution to journal › Article
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Mark
G-CSF prevents caspase 3 activation in Schwann cells after sciatic nerve transection, but does not improve nerve regeneration
(
- Contribution to journal › Article
- 2014
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Mark
Novel In Situ Activity Assays for the Quantitative Molecular Analysis of Neurodegenerative Processes in the Retina
(
- Contribution to journal › Article
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Mark
Knockout of PARG110 confers resistance to cGMP-induced toxicity in mammalian photoreceptors.
(
- Contribution to journal › Article
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Mark
How Long Does a Photoreceptor Cell Take to Die? Implications for the Causative Cell Death Mechanisms
(
- Contribution to journal › Article
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Mark
DNA methylation and differential gene regulation in photoreceptor cell death.
(
- Contribution to journal › Article
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Mark
Identification of a common non-apoptotic cell death mechanism in hereditary retinal degeneration.
(
- Contribution to journal › Article
- 2013
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Mark
Retinitis pigmentosa: rapid neurodegeneration is governed by slow cell death mechanisms
(
- Contribution to journal › Article
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Mark
Retinal degeneration depends on Bmi1 function and reactivation of cell cycle proteins
(
- Contribution to journal › Article
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Mark
Retinitis Pigmentosa: Over-expression of anti-ageing protein Klotho in degenerating photoreceptors.
2013) In Journal of Neurochemistry(
- Contribution to journal › Article
- 2011
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Mark
Calpain and PARP Activation during Photoreceptor Cell Death in P23H and S334ter Rhodopsin Mutant Rats
(
- Contribution to journal › Article
- 2010
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Mark
PARP1 Gene Knock-Out Increases Resistance to Retinal Degeneration without Affecting Retinal Function
(
- Contribution to journal › Article
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Mark
Tumor necrosis factor and its receptors in the neuroretina and retinal vasculature after ischemia-reperfusion injury in the pig retina.
(
- Contribution to journal › Article
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Mark
Excessive HDAC activation is critical for neurodegeneration in the rd1 mouse
(
- Contribution to journal › Article
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Mark
Photoreceptor rescue and toxicity induced by different calpain inhibitors
(
- Contribution to journal › Article
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Mark
Antioxidants rescue photoreceptors in rd1 mice: Relationship with thiol metabolism
(
- Contribution to journal › Article
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Mark
Human neural progenitor cells promote photoreceptor survival in retinal explants.
(
- Contribution to journal › Article
- 2009
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Mark
Study of Gene-Targeted Mouse Models of Splicing Factor Gene Prpf31 Implicated in Human Autosomal Dominant Retinitis Pigmentosa (RP)
(
- Contribution to journal › Article
-
Mark
PKG activity causes photoreceptor cell death in two retinitis pigmentosa models
(
- Contribution to journal › Article
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Mark
Serum-free retinal explant culture system and comparative rescue effects of LEDGF, GST, CNTF, BDNF, NGF, bFGF and antioxidants in the rd1 mouse model of retinitis pigmentosa
2009) p.263-299(
- Chapter in Book/Report/Conference proceeding › Book chapter
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Mark
Physiopathology of retinal degeneration in rd1 mouse model of retinitis pigmentosa : TGF-Β1, proteinases and oxidative stress mechanisms
2009) p.1-41(
- Chapter in Book/Report/Conference proceeding › Book chapter
- 2008
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Mark
Identification of paracrine neuroprotective candidate proteins by a functional assay-driven proteomics approach
(
- Contribution to journal › Article
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Mark
Photoreceptor Cell Death Mechanisms in Inherited Retinal Degeneration
(
- Contribution to journal › Scientific review
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Mark
rd1 Mouse retina shows an imbalance in the activity of cysteine protease cathepsins and their endogenous inhibitor cystatin C.
(
- Contribution to journal › Article
- 2007
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Mark
Significant photoreceptor rescue by treatment with a combination of antioxidants in an animal model for retinal degeneration.
(
- Contribution to journal › Article
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Mark
CNTF plus BDNF treatment and neuroprotective pathways in the rd1 mouse retina
(
- Contribution to journal › Article
-
Mark
Calpain activity in retinal degeneration.
(
- Contribution to journal › Scientific review
-
Mark
Excessive activation of poly(ADP-ribose) polymerase contributes to inherited photoreceptor degeneration in the retinal degeneration 1 mouse.
(
- Contribution to journal › Article
- 2006
-
Mark
Differential modification of phosducin protein in degenerating rd1 ret is associated with constitutively active CaMKII in rod outer segments.
(
- Contribution to journal › Article
-
Mark
rd1 Mouse Retina Shows Imbalance in Cellular Distribution and Levels of TIMP-1/MMP-9, TIMP-2/MMP-2 and Sulfated Glycosaminoglycans.
(
- Contribution to journal › Article
-
Mark
Calpain is activated in degenerating photoreceptors in the rd1 mouse.
(
- Contribution to journal › Article
-
Mark
Up-regulation and increased phosphorylation of protein kinase C (PKC) delta, mu and theta in the degenerating rd1 mouse retina.
(
- Contribution to journal › Article
- 2005
-
Mark
Decreased glutathione transferase levels in rd1/rd1 mouse retina: Replenishment protects photoreceptors in retinal explants.
(
- Contribution to journal › Article