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- 2024
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Mark
Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes
(
- Contribution to journal › Article
- 2023
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Mark
Identification of pathogenic GCK variants in patients with common type 2 diabetes can lead to discontinuation of pharmacological treatment
(
- Contribution to journal › Article
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Mark
Microbially Produced Imidazole Propionate Is Associated With Heart Failure and Mortality
(
- Contribution to journal › Article
- 2021
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Mark
Genome-Wide Association Analysis of Pancreatic Beta-Cell Glucose Sensitivity
(
- Contribution to journal › Article
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Mark
Profiles of Glucose Metabolism in Different Prediabetes Phenotypes, Classified by Fasting Glycemia, 2-Hour OGTT, Glycated Hemoglobin, and 1-Hour OGTT : An IMI DIRECT Study
(
- Contribution to journal › Article
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Mark
Processes Underlying Glycemic Deterioration in Type 2 Diabetes : An IMI DIRECT Study
(
- Contribution to journal › Article
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Mark
Inferring causal pathways between metabolic processes and liver fat accumulation: an IMI DIRECT study
2021) In medRxiv(
- Working paper/Preprint › Preprint in preprint archive
- 2020
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Mark
The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes : an IMI DIRECT study
(
- Contribution to journal › Article
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Mark
Dietary metabolite profiling brings new insight into the relationship between nutrition and metabolic risk : An IMI DIRECT study
(
- Contribution to journal › Article
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Mark
Post-load glucose subgroups and associated metabolic traits in individuals with type 2 diabetes : An IMI-DIRECT study
(
- Contribution to journal › Article
- 2019
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Mark
A novel rare CUBN variant and three additional genes identified in Europeans with and without diabetes : results from an exome-wide association study of albuminuria
(
- Contribution to journal › Article
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Mark
Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes
(
- Contribution to journal › Article
- 2018
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Mark
Brugada syndrome-associated genetic loci are associated with J-point elevation and an increased risk of cardiac arrest
(
- Contribution to journal › Article
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Mark
Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent
(
- Contribution to journal › Article
- 2017
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Mark
Causal relationship between obesity and serum testosterone status in men : A bidirectional mendelian randomization analysis
(
- Contribution to journal › Article
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Mark
Predicting glycated hemoglobin levels in the non-diabetic general population : Development and validation of the DIRECTDETECT prediction model-a DIRECT study
(
- Contribution to journal › Article
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Mark
New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals
(
- Contribution to journal › Article
- 2016
-
Mark
DNA methylation and gene expression of HIF3A : cross-tissue validation and associations with BMI and insulin resistance
(
- Contribution to journal › Article
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Mark
Insulin resistance is accompanied by increased fasting glucagon and delayed glucagon suppression in individuals with normal and impaired glucose regulation
(
- Contribution to journal › Article
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Mark
Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes
(
- Contribution to journal › Article
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Mark
FTO genotype and weight loss : systematic review and meta-analysis of 9563 individual participant data from eight randomised controlled trials
(
- Contribution to journal › Article
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Mark
Genome-wide association study of the modified stumvoll insulin sensitivity index identifies BCL2 and FAM19A2 as novel insulin sensitivity loci
(
- Contribution to journal › Article
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Mark
Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits
(
- Contribution to journal › Article
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Mark
A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease
(
- Contribution to journal › Article
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Mark
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.
(
- Contribution to journal › Article
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Mark
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension
(
- Contribution to journal › Article
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Mark
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.
(
- Contribution to journal › Article
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Mark
A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape
(
- Contribution to journal › Article
- 2015
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Mark
Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood.
(
- Contribution to journal › Article
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Mark
Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus.
(
- Contribution to journal › Article
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Mark
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility.
(
- Contribution to journal › Article
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Mark
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.
(
- Contribution to journal › Article
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Mark
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.
(
- Contribution to journal › Article
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Mark
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
(
- Contribution to journal › Article
- 2014
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Mark
Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium.
(
- Contribution to journal › Article
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Mark
Gene-Lifestyle Interaction and Type 2 Diabetes: The EPIC InterAct Case-Cohort Study.
(
- Contribution to journal › Article
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Mark
Loss-of-function mutations in SLC30A8 protect against type 2 diabetes.
(
- Contribution to journal › Article
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Mark
FTO genetic variants, dietary intake and body mass index: insights from 177 330 individuals.
(
- Contribution to journal › Article
- 2013
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Mark
Does DNA Methylation of PPARGC1A Influence Insulin Action in First Degree Relatives of Patients with Type 2 Diabetes?
(
- Contribution to journal › Article
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Mark
Genetic Variants Associated With Glycine Metabolism and Their Role in Insulin Sensitivity and Type 2 Diabetes
(
- Contribution to journal › Article
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Mark
The CTRB1/2 Locus Affects Diabetes Susceptibility and Treatment via the Incretin Pathway
(
- Contribution to journal › Article
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Mark
Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry. : combined analysis of 111,421 individuals of European ancestry
(
- Contribution to journal › Article
- 2012
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Mark
Validation of a multi-marker model for the prediction of incident type 2 diabetes mellitus: Combined results of the Inter99 and Botnia studies.
(
- Contribution to journal › Article
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Mark
TFAP2B influences the effect of dietary fat on weight loss under energy restriction
(
- Contribution to journal › Article
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Mark
Apolipoprotein(a) Genetic Sequence Variants Associated With Systemic Atherosclerosis and Coronary Atherosclerotic Burden But Not With Venous Thromboembolism
(
- Contribution to journal › Article
-
Mark
No Interactions Between Previously Associated 2-Hour Glucose Gene Variants and Physical Activity or BMI on 2-Hour Glucose Levels
(
- Contribution to journal › Article
- 2011
-
Mark
The FOXO3A rs2802292 G-Allele Associates with Improved Peripheral and Hepatic Insulin Sensitivity and Increased Skeletal Muscle-FOXO3A mRNA Expression in Twins.
(
- Contribution to journal › Article
-
Mark
Improved glycemic control induced by both metformin and repaglinide is associated with a reduction in blood levels of 3-deoxyglucosone in nonobese patients with type 2 diabetes
(
- Contribution to journal › Article
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Mark
Physical Activity Attenuates the Influence of FTO Variants on Obesity Risk: A Meta-Analysis of 218,166 Adults and 19,268 Children
(
- Contribution to journal › Article
- 2010
-
Mark
Impact of rs361072 in the Phosphoinositide 3-Kinase p110 beta Gene on Whole-Body Glucose Metabolism and Subunit Protein Expression in Skeletal Muscle
(
- Contribution to journal › Article