Targeted therapies in leukemia

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2016
Mark IL1RAP antibodies block IL-1-induced expansion of candidate CML stem cells and mediate cell killing in xenograft models
Ågerstam, Helena ^LU ; Hansen, Nils ^LU ; von Palffy, Sofia ^LU ; Sandén, Carl ^LU ; Reckzeh, Kristian ^LU ; Karlsson, Christine ^LU ; Lilljebjörn, Henrik ^LU ; Landberg, Niklas ^LU ; Askmyr, Maria ^LU and Högberg, Carl ^LU , et al. (2016) In Blood 128(23). p.2683-2693
- Contribution to journal › Article
2015
Mark Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia.
Ågerstam, Helena ^LU ; Karlsson, Christine ^LU ; Hansen, Nils ^LU ; Sandén, Carl ^LU ; Askmyr, Maria ^LU ; von Palffy, Sofia ^LU ; Högberg, Carl ^LU ; Rissler, Marianne ^LU ; Wunderlich, Mark and Juliusson, Gunnar ^LU , et al. (2015) In Proceedings of the National Academy of Sciences 112(34). p.10786-10791
- Contribution to journal › Article
Mark Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS
Krönke, Jan ; Fink, Emma C. ; Hollenbach, Paul W. ; MacBeth, Kyle J. ; Hurst, Slater N. ; Udeshi, Namrata D. ; Chamberlain, Philip P. ; Mani, D. R. ; Man, Hon Wah and Gandhi, Anita K. , et al. (2015) In Nature 523(7559). p.183-188
- Contribution to journal › Article
2014
Mark Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia
Järås, Marcus ^LU ; Miller, Peter G. ; Chu, Lisa P. ; Puram, Rishi V. ; Fink, Emma C. ; Schneider, Rebekka K. ; Al-Shahrour, Fatima ; Peña, Pablo ^LU ; Breyfogle, L. Jordan and Hartwell, Kimberly A. , et al. (2014) In Journal of Experimental Medicine 211(4). p.605-612
- Contribution to journal › Article
2010
Mark Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein.
Järås, Marcus ^LU ; Johnels, Petra ^LU ; Hansen, Nils ^LU ; Ågerstam, Helena ^LU ; Tsapogas, Panagiotis ; Rissler, Marianne ^LU ; Lassen, Carin ^LU ; Olofsson, Tor ^LU ; Bjerrum, Ole Weis and Richter, Johan ^LU , et al. (2010) In Proceedings of the National Academy of Sciences 107(37). p.16280-16285
- Contribution to journal › Article

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