Lotta Happonen

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2024
Mark Immunomodulating Enzymes from Streptococcus pyogenes-In Pathogenesis, as Biotechnological Tools, and as Biological Drugs
Happonen, Lotta ^LU and Collin, Mattias ^LU (2024) In Microorganisms 12(1).
- Contribution to journal › Scientific review
Mark Quantification of adaptive immune responses against protein binding interfaces in the streptococcal M1 protein
Torres-Sangiao, E ^LU ; Happonen, L ^LU ; Heusel, M ^LU ; Palm, F ^LU ; Gueto-Tettay, C ^LU ; Malmström, L ^LU ; Shannon, O ^LU and Malmström, J ^LU (2024) In Molecular and Cellular Proteomics 23(5).
- Contribution to journal › Article
Mark The hinge-engineered IgG1-IgG3 hybrid subclass IgGh47 potently enhances Fc-mediated function of anti-streptococcal and SARS-CoV-2 antibodies
Izadi, Arman ^LU ; Karami, Yasaman ; Bratanis, Eleni ^LU ; Wrighton, Sebastian ^LU ; Khakzad, Hamed ; Nyblom, Maria ; Olofsson, Berit ^LU ; Happonen, Lotta ^LU ; Tang, Di ^LU and Sundwall, Martin ^LU , et al. (2024) In Nature Communications 15. p.1-22
- Contribution to journal › Article
2023
Mark A human monoclonal antibody bivalently binding two different epitopes in streptococcal M protein mediates immune function
Bahnan, Wael ^LU ; Happonen, Lotta ^LU ; Khakzad, Hamed ; Kumra Ahnlide, Vibha ^LU ; de Neergaard, Therese ^LU ; Wrighton, Sebastian ^LU ; André, Oscar ^LU ; Bratanis, Eleni ^LU ; Tang, Di ^LU and Hellmark, Thomas ^LU , et al. (2023) In EMBO Molecular Medicine 15(2). p.1-21
- Contribution to journal › Article
Mark Multienzyme deep learning models improve peptide de novo sequencing by mass spectrometry proteomics
Gueto-Tettay, Carlos ^LU ; Tang, Di ^LU ; Happonen, Lotta ^LU ; Heusel, Moritz ^LU ; Khakzad, Hamed ; Malmström, Johan ^LU and Malmström, Lars ^LU (2023) In PLoS Computational Biology 19(1).
- Contribution to journal › Article
Mark The intracellular helical bundle of human glucose transporter GLUT4 is important for complex formation with ASPL
Huang, Peng ^LU ; Åbacka, Hannah ^LU ; Varela, Daniel ^LU ; Venskutonytė, Raminta ^LU ; Happonen, Lotta ^LU ; Bogan, Jonathan S. ; Gourdon, Pontus ^LU ; Amiry-Moghaddam, Mahmood R. ; André, Ingmar and Lindkvist-Petersson, Karin ^LU (2023) In FEBS Open Bio 13(11). p.2094-2107
- Contribution to journal › Article
Mark Reduced binding of apoE4 to complement factor H promotes amyloid-β oligomerization and neuroinflammation
Chernyaeva, Larisa ; Ratti, Giorgio ; Teirilä, Laura ; Fudo, Satoshi ; Rankka, Uni ; Pelkonen, Anssi ; Korhonen, Paula ; Leskinen, Katarzyna ; Keskitalo, Salla and Salokas, Kari , et al. (2023) In EMBO Reports 24(7).
- Contribution to journal › Article
Mark Affinity-Purification Combined with Crosslinking Mass Spectrometry for Identification and Structural Modeling of Host-Pathogen Protein-Protein Complexes
Happonen, Lotta J. ^LU (2023) In Methods in molecular biology (Clifton, N.J.) p.181-200
- Chapter in Book/Report/Conference proceeding › Book chapter
Mark IdeS, a secreted proteinase of Streptococcus pyogenes, is bound to a nuclease at the bacterial surface where it inactivates opsonizing IgG antibodies
Frick, Inga Maria ^LU ; Happonen, Lotta ^LU ; Wrighton, Sebastian ^LU ; Nordenfelt, Pontus ^LU and Björck, Lars ^LU (2023) In Journal of Biological Chemistry 299(11). p.1-16
- Contribution to journal › Article
Mark Autophagy-mediated control of ribosome homeostasis in oncogene-induced senescence
López, Aida Rodríguez ; Jørgensen, Maria H. ; Havelund, Jesper F. ; Arendrup, Frederic S. ; Kolapalli, Srinivasa Prasad ; Nielsen, Thorbjørn M. ; Pais, Eva ; Beese, Carsten Jörn ; Abdul-Al, Ahmad and Vind, Anna Constance , et al. (2023) In Cell Reports 42(11). p.1-23
- Contribution to journal › Article