Axel Hyrenius Wittsten

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2022
Mark Modular design of synthetic receptors for programmed gene regulation in cell therapies
Zhu, Iowis ; Liu, Raymond ; Garcia, Julie M. ; Hyrenius-Wittsten, Axel ^LU ; Piraner, Dan I. ; Alavi, Josef ; Israni, Divya V. ; Liu, Bin ; Khalil, Ahmad S. and Roybal, Kole T. (2022) In Cell 185(8). p.16-1443
- Contribution to journal › Article
Mark Duplex Sequencing Uncovers Recurrent Low-frequency Cancer-associated Mutations in Infant and Childhood KMT2A-rearranged Acute Leukemia
Pilheden, Mattias ^LU ; Ahlgren, Louise ^LU ; Hyrenius-Wittsten, Axel ^LU ; Gonzalez-Pena, Veronica ; Sturesson, Helena ^LU ; Hansen Marquart, Hanne Vibeke ; Lausen, Birgitte ; Castor, Anders ^LU ; Pronk, Cornelis Jan and Barbany, Gisela , et al. (2022) In HemaSphere 6(10). p.1-8
- Contribution to journal › Article
2021
Mark Targeting GLUT1 in acute myeloid leukemia to overcome cytarabine resistance
Åbacka, Hannah ^LU ; Hansen, Jesper S ^LU ; Huang, Peng ^LU ; Venskutonytė, Raminta ^LU ; Hyrenius-Wittsten, Axel ^LU ; Poli, Giulio ; Tuccinardi, Tiziano ; Granchi, Carlotta ; Minutolo, Filippo and Hagström-Andersson, Anna K ^LU , et al. (2021) In Haematologica 106(4). p.1163-1166
- Contribution to journal › Article
2019
Mark FLT3 ^N676K drives acute myeloid leukemia in a xenograft model of KMT2A-MLLT3 leukemogenesis
Hyrenius-Wittsten, Axel ^LU ; Pilheden, Mattias ^LU ; Falqués-Costa, Antoni ; Eriksson, Mia ^LU ; Sturesson, Helena ^LU ; Schneider, Pauline ; Wander, Priscilla ; Garcia-Ruiz, Cristian ^LU ; Liu, Jian and Ågerstam, Helena ^LU , et al. (2019) In Leukemia 33(9). p.2310-2314
- Contribution to journal › Letter
2018
Mark De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia
Hyrenius-Wittsten, Axel ^LU ; Pilheden, Mattias ^LU ; Sturesson, Helena ^LU ; Hansson, Jenny ^LU ; Walsh, Michael P. ; Song, Guangchun ; Kazi, Julhash U. ^LU ; Liu, Jian ; Ramakrishan, Ramprasad ^LU and Garcia-Ruiz, Cristian ^LU , et al. (2018) In Nature Communications 9(1).
- Contribution to journal › Article
2017
Mark Molecular Interrogation and Functional Studies of Acute Leukemia
Hyrenius Wittsten, Axel ^LU (2017)
- Thesis › Doctoral thesis (compilation)
2016
Mark Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia
Lilljebjörn, Henrik ^LU ; Henningsson, Rasmus ^LU ; Hyrenius-Wittsten, Axel ^LU ; Olsson, Linda ^LU ; Orsmark-Pietras, Christina ^LU ; Von Palffy, Sofia ^LU ; Askmyr, Maria ^LU ; Rissler, Marianne ^LU ; Schrappe, Martin and Cario, Gunnar , et al. (2016) In Nature Communications 7.
- Contribution to journal › Article
Mark Genomic profiling and directed ex vivo drug analysis of an unclassifiable myelodysplastic/myeloproliferative neoplasm progressing into acute myeloid leukemia
Hyrenius-Wittsten, Axel ^LU ; Sturesson, Helena ^LU ; Bidgoli, Mahtab ^LU ; Jonson, Tord ^LU ; Ehinger, Mats ^LU ; Lilljebjörn, Henrik ^LU ; Scheding, Stefan ^LU and Andersson, Anna K. ^LU (2016) In Genes Chromosomes and Cancer 55(11). p.847-854
- Contribution to journal › Article
2014
Mark HIF-1α can act as a tumor suppressor gene in murine Acute Myeloid Leukemia.
Velasco, Talia ^LU ; Hyrenius Wittsten, Axel ^LU ; Rehn, Matilda ^LU ; Bryder, David ^LU and Cammenga, Jörg ^LU (2014) In Blood 124(24). p.3597-3607
- Contribution to journal › Article