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Probiotic fruit beverages with different polyphenol profiles attenuated early insulin response

Xu, Jie LU ; Jönsson, Tommy LU ; Plaza, Merichel LU ; Håkansson, Åsa LU ; Antonsson, Martin LU ; Ahrén, Irini Lazou; Turner, Charlotta LU ; Spégel, Peter LU and Granfeldt, Yvonne LU (2018) In Nutrition Journal 17(1).
Abstract

Background: Consumption of polyphenol-rich fruits and vegetables may improve postprandial glucose and insulin levels and hence promote well-being. Previously it has been observed that consumption of bilberry decreases the postprandial insulin demand. The intention with the present study was to compare the impact of different supplements with various polyphenol profiles, on the postprandial glucose and insulin responses in healthy young adults. Methods: In a randomized, controlled, crossover study the postprandial glycemic and insulin responses were observed in eleven healthy adults after intake of five different beverages containing bilberry (European blueberry), blackcurrant, beetroot, mango and rose hip, respectively; all drinks were... (More)

Background: Consumption of polyphenol-rich fruits and vegetables may improve postprandial glucose and insulin levels and hence promote well-being. Previously it has been observed that consumption of bilberry decreases the postprandial insulin demand. The intention with the present study was to compare the impact of different supplements with various polyphenol profiles, on the postprandial glucose and insulin responses in healthy young adults. Methods: In a randomized, controlled, crossover study the postprandial glycemic and insulin responses were observed in eleven healthy adults after intake of five different beverages containing bilberry (European blueberry), blackcurrant, beetroot, mango and rose hip, respectively; all drinks were enriched with the same composition of fermented oatmeal and probiotics. The control was a glucose drink. The profile and content of the polyphenols in the different beverages were determined by HPLC-DAD analysis. The antioxidative capacity of the different beverages were measured by TEAC and DPPH assays. Results: Beverages containing bilberry, blackcurrant, mango or rose hip significantly attenuated the early postprandial insulin response (0-90 min), but showed no effect on glucose response. Drinks with bilberry or rose hip reduced the insulin response from the very early phase (0-30 min), and had significantly lower insulin index compared with the control. The efficiency of the bilberry and rose hip to decrease early postprandial insulin responses correlated with higher phenolic contents. Conclusions: Supplements with bilberry, blackcurrant, mango or rose hip in the tested probiotic and oatmeal enriched beverage attenuated early-phase insulin response, but had no effect on the postprandial glycemic response. The improved ability of bilberry and rose hip to lower the very early phase of insulin response seems to be due to a higher phenolic content. Trial registration: The study was retrospectively registered at ClinicalTrials.gov with number NCT03159065.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Beetroot, Bilberries, Blackcurrant, Mango, Postprandial insulin response, Rose hip
in
Nutrition Journal
volume
17
issue
1
publisher
BioMed Central
external identifiers
  • scopus:85042705950
  • pmid:29486772
ISSN
1475-2891
DOI
10.1186/s12937-018-0335-0
language
English
LU publication?
yes
id
605f96dd-8636-41b4-84b4-99724beae5f8
date added to LUP
2018-03-26 15:43:43
date last changed
2019-08-14 04:12:57
@article{605f96dd-8636-41b4-84b4-99724beae5f8,
  abstract     = {<p>Background: Consumption of polyphenol-rich fruits and vegetables may improve postprandial glucose and insulin levels and hence promote well-being. Previously it has been observed that consumption of bilberry decreases the postprandial insulin demand. The intention with the present study was to compare the impact of different supplements with various polyphenol profiles, on the postprandial glucose and insulin responses in healthy young adults. Methods: In a randomized, controlled, crossover study the postprandial glycemic and insulin responses were observed in eleven healthy adults after intake of five different beverages containing bilberry (European blueberry), blackcurrant, beetroot, mango and rose hip, respectively; all drinks were enriched with the same composition of fermented oatmeal and probiotics. The control was a glucose drink. The profile and content of the polyphenols in the different beverages were determined by HPLC-DAD analysis. The antioxidative capacity of the different beverages were measured by TEAC and DPPH assays. Results: Beverages containing bilberry, blackcurrant, mango or rose hip significantly attenuated the early postprandial insulin response (0-90 min), but showed no effect on glucose response. Drinks with bilberry or rose hip reduced the insulin response from the very early phase (0-30 min), and had significantly lower insulin index compared with the control. The efficiency of the bilberry and rose hip to decrease early postprandial insulin responses correlated with higher phenolic contents. Conclusions: Supplements with bilberry, blackcurrant, mango or rose hip in the tested probiotic and oatmeal enriched beverage attenuated early-phase insulin response, but had no effect on the postprandial glycemic response. The improved ability of bilberry and rose hip to lower the very early phase of insulin response seems to be due to a higher phenolic content. Trial registration: The study was retrospectively registered at ClinicalTrials.gov with number NCT03159065.</p>},
  articleno    = {34},
  author       = {Xu, Jie and Jönsson, Tommy and Plaza, Merichel and Håkansson, Åsa and Antonsson, Martin and Ahrén, Irini Lazou and Turner, Charlotta and Spégel, Peter and Granfeldt, Yvonne},
  issn         = {1475-2891},
  keyword      = {Beetroot,Bilberries,Blackcurrant,Mango,Postprandial insulin response,Rose hip},
  language     = {eng},
  month        = {02},
  number       = {1},
  publisher    = {BioMed Central},
  series       = {Nutrition Journal},
  title        = {Probiotic fruit beverages with different polyphenol profiles attenuated early insulin response},
  url          = {http://dx.doi.org/10.1186/s12937-018-0335-0},
  volume       = {17},
  year         = {2018},
}