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- 2024
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Mark
BAMLET administration via drinking water inhibits intestinal tumor development and promotes long-term health
(
- Contribution to journal › Article
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Mark
Therapeutic Effects of IL-1RA against Acute Bacterial Infections, including Antibiotic-Resistant Strains
(
- Contribution to journal › Article
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Mark
Similar immune responses to alpha1-oleate and Bacillus Calmette–Guérin treatment in patients with bladder cancer
(
- Contribution to journal › Article
- 2023
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Mark
Long-term prevention of bladder cancer progression by alpha1-oleate alone or in combination with chemotherapy
(
- Contribution to journal › Article
- 2022
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Mark
Lipid bilayer composition as a determinant of cancer cell sensitivity to tumoricidal protein-lipid complexes
(
- Contribution to journal › Article
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Mark
Immunomodulation therapy offers new molecular strategies to treat UTI
(
- Contribution to journal › Scientific review
- 2021
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Mark
Bladder cancer therapy using a conformationally fluid tumoricidal peptide complex
(
- Contribution to journal › Article
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Mark
Molecular determinants of disease severity in urinary tract infection
(
- Contribution to journal › Scientific review
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Mark
A bacterial protease depletes c-MYC and increases survival in mouse models of bladder and colon cancer
(
- Contribution to journal › Article
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Mark
A scientific journey from discovery to validation of efficacy in cancer patients : HAMLET and alpha1-oleate
(
- Contribution to journal › Article
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Mark
Collateral effects of deletion of nlpD on rpoS and rpoS-dependent genes. Reply.
(
- Contribution to journal › Debate/Note/Editorial
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Mark
Active bacterial modification of the host environment through RNA polymerase II inhibition
(
- Contribution to journal › Article
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Mark
Immunomodulation—A Molecular Solution to Treating Patients with Severe Bladder Pain Syndrome?
(
- Contribution to journal › Article
- 2020
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Mark
Bladder cancer therapy without toxicity—A dose-escalation study of alpha1-oleate
(
- Contribution to journal › Article
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Mark
Peptide-Oleate Complexes Create Novel Membrane-Bound Compartments
(
- Contribution to journal › Article
- 2019
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Mark
Beta-sheet-specific interactions with heat shock proteins define a mechanism of delayed tumor cell death in response to HAMLET
(
- Contribution to journal › Article
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Mark
Fimbriae reprogram host gene expression - Divergent effects of P and type 1 fimbriae
(
- Contribution to journal › Article
- 2018
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Mark
Neuroepithelial control of mucosal inflammation in acute cystitis
(
- Contribution to journal › Article
- 2017
-
Mark
HAMLET – A protein-lipid complex with broad tumoricidal activity
(
- Contribution to journal › Scientific review
- 2016
-
Mark
Urinary Tract Infection Molecular Mechanisms and Clinical Translation.
(
- Contribution to journal › Scientific review
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Mark
A Comparative Analysis of the Mechanism of Toll-Like Receptor-Disruption by TIR-Containing Protein C from Uropathogenic Escherichia coli.
(
- Contribution to journal › Article
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Mark
Asymtomatic Bacteriuria as a Model to Study the Coevolution of Hosts and Bacteria.
(
- Contribution to journal › Scientific review
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Mark
Protein-dependent membrane interaction of a partially disordered protein complex with oleic acid : Implications for cancer lipidomics
(
- Contribution to journal › Article
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Mark
Susceptibility to urinary tract infection : Benefits and hazards of the antibacterial host response
(
- Contribution to journal › Scientific review
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Mark
Bacterial suppression of RNA polymerase II-dependent host gene expression
(
- Contribution to journal › Scientific review
-
Mark
Deliberate establishment of asymptomatic bacteriuria—a novel strategy to prevent recurrent UTI
(
- Contribution to journal › Scientific review
-
Mark
Molecular Basis of Acute Cystitis Reveals Susceptibility Genes and Immunotherapeutic Targets
(
- Contribution to journal › Article
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Mark
IRF7 inhibition prevents destructive innate immunity-A target for nonantibiotic therapy of bacterial infections
(
- Contribution to journal › Article
-
Mark
Uropathogenic Escherichia coli strain CFT073 disrupts NLRP3 inflammasome activation
(
- Contribution to journal › Article
- 2015
-
Mark
Protein receptor-independent plasma membrane remodeling by HAMLET: a tumoricidal protein-lipid complex.
(
- Contribution to journal › Article
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Mark
The Molecular Motor F-ATP Synthase Is Targeted by the Tumoricidal Protein HAMLET.
(
- Contribution to journal › Article
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Mark
Targeting of nucleotide-binding proteins by HAMLET-a conserved tumor cell death mechanism.
2015) In Oncogene(
- Contribution to journal › Article
-
Mark
Innate immunity and genetic determinants of urinary tract infection susceptibility.
(
- Contribution to journal › Scientific review
- 2014
-
Mark
The Humoral Pattern Recognition Molecule PTX3 Is a Key Component of Innate Immunity against Urinary Tract Infection.
(
- Contribution to journal › Article
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Mark
Polyethyleneimine is a potent systemic adjuvant for glycoprotein antigens.
(
- Contribution to journal › Article
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Mark
Prevention and treatment of colon cancer by peroral administration of HAMLET (human α-lactalbumin made lethal to tumour cells).
(
- Contribution to journal › Article
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Mark
Rare emergence of symptoms during long-term asymptomatic E. coli 83972 carriage, without altered virulence factor repertoire.
(
- Contribution to journal › Article
- 2013
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Mark
Electrostatic interactions play an essential role in the binding of oleic acid with a-lactalbumin in the HAMLET-like complex: A study using charge-specific chemical modifications
(
- Contribution to journal › Article
-
Mark
A Unifying Mechanism for Cancer Cell Death through Ion Channel Activation by HAMLET.
(
- Contribution to journal › Article
-
Mark
Lipids as Tumoricidal Components of Human Alpha-lactalbumin Made Lethal to Tumor Cells (HAMLET); Unique and Shared Effects on Signaling and Death.
(
- Contribution to journal › Article
-
Mark
Urinary tract infections in children: microbial virulence versus host susceptibility.
(
- Contribution to journal › Article
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Mark
Preface
(
- Chapter in Book/Report/Conference proceeding › Book chapter
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Mark
Bacterial control of host gene expression through RNA polymerase II
(
- Contribution to journal › Article
- 2012
-
Mark
Low Resolution Solution Structure of HAMLET and the Importance of Its Alpha-Domains in Tumoricidal Activity.
(
- Contribution to journal › Article
-
Mark
HAMLET Forms Annular Oligomers When Deposited with Phospholipid Monolayers
(
- Contribution to journal › Article
-
Mark
Polyethyleneimine is a potent mucosal adjuvant for viral glycoprotein antigens
(
- Contribution to journal › Article
-
Mark
Do Escherichia coli strains causing acute cystitis have a distinct virulence repertoire?
(
- Contribution to journal › Article
-
Mark
Alternatively folded proteins with unexpected beneficial functions
(
- Contribution to journal › Article
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Mark
Comparison of Asymptomatic Bacteriuria Escherichia coli Isolates from Healthy Individuals versus Those from Hospital Patients Shows that Long-Term Bladder Colonization Selects for Attenuated Virulence Phenotypes
(
- Contribution to journal › Article
-
Mark
HAMLET: functional properties and therapeutic potential.
(
- Contribution to journal › Article
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Mark
Susceptibility to acute pyelonephritis or asymptomatic bacteriuria: Host-pathogen interaction in urinary tract infections.
(
- Contribution to journal › Article
- 2011
-
Mark
Acute pyelonephritis and renal scarring are caused by dysfunctional innate immunity in mCxcr2 heterozygous mice.
(
- Contribution to journal › Article
-
Mark
Apoptosis-Like Death in Bacteria Induced by HAMLET, a Human Milk Lipid-Protein Complex
(
- Contribution to journal › Article
-
Mark
HAMLET Binding to α-Actinin Facilitates Tumor Cell Detachment.
(
- Contribution to journal › Article
-
Mark
MiR-129-5p is required for histone deacetylase inhibitor-induced cell death in thyroid cancer cells
(
- Contribution to journal › Article
-
Mark
Conserved features of cancer cells define their sensitivity to HAMLET-induced death; c-Myc and glycolysis.
(
- Contribution to journal › Article
-
Mark
Genetics of innate immunity and UTI susceptibility.
(
- Contribution to journal › Article
-
Mark
Genetic control of the variable innate immune response to asymptomatic bacteriuria.
(
- Contribution to journal › Article
- 2010
-
Mark
Host Imprints on Bacterial Genomes-Rapid, Divergent Evolution in Individual Patients
(
- Contribution to journal › Article
-
Mark
HAMLET interacts with lipid membranes and perturbs their structure and integrity.
(
- Contribution to journal › Article
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Mark
Structure and function of human α-lactalbumin made lethal to tumor cells (HAMLET)-type complexes.
(
- Contribution to journal › Scientific review
-
Mark
Pathogen specific, IRF3-dependent signaling and innate resistance to human kidney infection.
(
- Contribution to journal › Article
-
Mark
Inhibition of TIR domain signaling by TcpC: MyD88-dependent and independent effects on Escherichia coli virulence.
(
- Contribution to journal › Article
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Mark
Toll-Like Receptor 4 Promoter Polymorphisms: Common TLR4 Variants May Protect against Severe Urinary Tract Infection.
(
- Contribution to journal › Article
-
Mark
HAMLET Treatment Delays Bladder Cancer Development.
(
- Contribution to journal › Article
- 2009
-
Mark
Virulence properties of asymptomatic bacteriuria Escherichia coli
(
- Contribution to journal › Article
-
Mark
Characterizing Escherichia coli asymptomatic bacteriuria (ABU) - what drives their successful silent colonization?
2009) 61st Conference of the Deutschen-Gesellschaft-fur-Hygiene-und-Microbiologie In International Journal of Medical Microbiology 299. p.54-54(
- Contribution to journal › Published meeting abstract
-
Mark
Can misfolded proteins be beneficial? The HAMLET case.
(
- Contribution to journal › Scientific review
-
Mark
alpha-Lactalbumin, Engineered to be Non-native and Inactive, Kills Tumor Cells when in Complex with Oleic Acid: A new biological function resulting from partial unfolding.
(
- Contribution to journal › Article
-
Mark
Therapeutic Effect of Blocking CXCR2 on Neutrophil Recruitment and Dextran Sodium Sulfate-Induced Colitis
(
- Contribution to journal › Article
-
Mark
HAMLET (human alpha-lactalbumin made lethal to tumor cells) triggers autophagic tumor cell death.
(
- Contribution to journal › Article
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Mark
Changes in proteasome structure and function caused by HAMLET in tumor cells.
(
- Contribution to journal › Article
-
Mark
HAMLET, a tumoricidal molecular complex from human milk
2009) 6th International Symposium on the Intraductal Approach to Breast Cancer In BMC Proceedings 3(Suppl 5). p.11-11(
- Contribution to journal › Published meeting abstract
- 2008
-
Mark
Apoptosis and tumor cell death in response to HAMLET (human alpha-lactalbumin made lethal to tumor cells).
(
- Contribution to journal › Scientific review
-
Mark
Pathogenomics: An updated European Research Agenda
(
- Contribution to journal › Letter
-
Mark
Shiga toxin-mediated disease in MyD88-deficient mice infected with Escherichia coli O157:H7.
(
- Contribution to journal › Article
-
Mark
Asymptomatic Bacteriuria: An adaptive challenge for Escherichia coli within the urinary tract
2008) 60th Annual Meeting of the Deutschen-Gesellschaft-fur-Hygiene-und-Mikrobiologie In International Journal of Medical Microbiology 298. p.76-76(
- Contribution to journal › Published meeting abstract
-
Mark
Subversion of Toll-like receptor signaling by a unique family of bacterial Toll/interleukin-1 receptor domain-containing proteins
(
- Contribution to journal › Article
-
Mark
Effects of epithelial and neutrophil CXCR2 on innate immunity and resistance to kidney infection.
(
- Contribution to journal › Article
-
Mark
TLR- and CXCR1-dependent innate immunity: insights into the genetics of urinary tract infections.
(
- Contribution to journal › Scientific review
-
Mark
Molecular basis of commensalism in the urinary tract: low virulence or virulence attenuation?
(
- Contribution to journal › Article
- 2007
-
Mark
Ceramide as a TLR4 agonist; a putative signalling intermediate between sphingolipid receptors for microbial ligands and TLR4.
(
- Contribution to journal › Article
-
Mark
Do type 1 fimbriae promote inflammation in the human urinary tract?
(
- Contribution to journal › Article
-
Mark
A genetic basis of susceptibility to acute pyelonephritis.
(
- Contribution to journal › Article
-
Mark
HAMLET, protein folding, and tumor cell death
(
- Contribution to journal › Scientific review
-
Mark
Inherited susceptibility to acute pyelonephritis: a family study of urinary tract infection.
(
- Contribution to journal › Article
-
Mark
Fimbrial lectins influence the chemokine repertoire in the urinary tract mucosa.
(
- Contribution to journal › Article
-
Mark
Urinary tract infections revisited.
(
- Contribution to journal › Letter
-
Mark
Histone deacetylase inhibitors promote the tumoricidal effect of HAMLET.
(
- Contribution to journal › Article
-
Mark
Reduced Toll-like receptor 4 expression in children with asymptomatic bacteriuria
(
- Contribution to journal › Article
-
Mark
Bladder cancers respond to intravesical instillation of HAMLET (human alpha-lactalbumin made lethal to tumor cells).
(
- Contribution to journal › Article
- 2006
-
Mark
HAMLET triggers apoptosis but tumor cell death is independent of caspases, Bcl-2 and p53.
(
- Contribution to journal › Article
-
Mark
Lipopolysaccharide from enterohemorrhagic Escherichia coli binds to platelets via TLR4 and CD62 and is detected on circulating platelets in patients with hemolytic uremic syndrome.
(
- Contribution to journal › Article
-
Mark
Uropathogenic Escherichia coli as a model of host-parasite interaction.
(
- Contribution to journal › Scientific review
-
Mark
Molecular characterization of the Escherichia coli asymptomatic bacteriuria strain 83972: The taming of a pathogen
(
- Contribution to journal › Article
-
Mark
alpha-Lactalbumin species variation, HAMLET formation, and tumor cell death.
(
- Contribution to journal › Article
-
Mark
Glycolipid receptor depletion as an approach to specific antimicrobial therapy.
(
- Contribution to journal › Scientific review
-
Mark
Unfolded Protein Overload, Proteasome Activation and Death in HAMLET-Treated Tumor Cells
2006) Ubiquitin and Cancer: From Molecular Targets and Mechanisms to the Clinic In IDrugs 9(3). p.29-29(
- Contribution to journal › Published meeting abstract
-
Mark
Mechanism of pathogen-specific TLR4 activation in the mucosa: Fimbriae, recognition receptors and adaptor protein selection.
(
- Contribution to journal › Article
- 2005
-
Mark
Expression of nitric oxide synthase isoforms in the mouse kidney: cellular localization and influence by lipopolysaccharide and Toll-like receptor 4.
(
- Contribution to journal › Article