Urothelial Cancer Genomics
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- 2024
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Metastasis and recurrence patterns in the molecular subtypes of urothelial bladder cancer
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- Contribution to journal › Article
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Distinct Infiltration of T Cell Populations in Bladder Cancer Molecular Subtypes
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- Contribution to journal › Article
- 2023
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UROSCAN and UROSCANSEQ : a large-scale multicenter effort towards translation of molecular bladder cancer subtypes into clinical practice–from biobank to RNA-sequencing in real time
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- Contribution to journal › Article
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The Lund taxonomy for bladder cancer classification – from gene expression clustering to cancer cell molecular phenotypes, and back again
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- Contribution to journal › Scientific review
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Tumor Biomarkers for Bacillus Calmette-Guérin Response : What We Get Is Not What We Want
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- Contribution to journal › Debate/Note/Editorial
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Predictive value of molecular subtypes and APOBEC3G for adjuvant chemotherapy in urothelial bladder cancer
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- Contribution to journal › Article
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Urodrill - a novel MRI-guided endoscopic biopsy technique to sample and molecularly classify muscle-invasive bladder cancer without fractionating the specimen during transurethral resection
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- Contribution to journal › Article
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Restoring tumor immunogenicity with dendritic cell reprogramming
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- Contribution to journal › Article
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Re : Alexander Cox, Niklas Klümper, Johannes Stein, et al. Molecular Urothelial Tumor Cell Subtypes Remain Stable During Metastatic Evolution. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2023.03.020
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- Contribution to journal › Letter
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What is a Bladder Cancer Molecular Subtype?
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- Contribution to journal › Scientific review
- 2022
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A quantitative polymerase chain reaction based method for molecular subtype classification of urinary bladder cancer—Stromal gene expressions show higher prognostic values than intrinsic tumor genes
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- Contribution to journal › Article
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Different Responses to Neoadjuvant Chemotherapy in Urothelial Carcinoma Molecular Subtypes
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- Contribution to journal › Article
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A comparison of rule-based and centroid single-sample multiclass predictors for transcriptomic classification
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- Contribution to journal › Article
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Diagnostic and prognostic implications of a three-antibody molecular subtyping algorithm for non-muscle invasive bladder cancer
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- Contribution to journal › Article
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Reply to Joep J. de Jong and Ewan A. Gibb's Letter to the Editor re: Gottfrid Sjödahl, Johan Abrahamsson, Karin Holmsten, et al. Different Responses to Neoadjuvant Chemotherapy in Urothelial Carcinoma Molecular Subtypes. Eur Urol. 2022;81:316-7. Neoadjuvant Chemotherapy Response in Muscle-invasive Bladder Cancer: Differences in Intrinsic Biology or Subtyping Nomenclature?
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- Contribution to journal › Letter
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Molecular pathology of the non-luminal Ba/Sq-like and Sc/NE-like classes of urothelial tumours : An integrated immunohistochemical analysis
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- Contribution to journal › Article
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Immunohistochemical Assays for Bladder Cancer Molecular Subtyping : Optimizing Parsimony and Performance of Lund Taxonomy Classifiers
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- Contribution to journal › Article
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Molecular Subtypes as a Basis for Stratified Use of Neoadjuvant Chemotherapy for Muscle-Invasive Bladder Cancer—A Narrative Review
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- Contribution to journal › Scientific review
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Patient-Derived Bladder Cancer Organoid Models in Tumor Biology and Drug Testing : A Systematic Review
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- Contribution to journal › Scientific review
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The Lund Molecular Taxonomy Applied to Non-Muscle-Invasive Urothelial Carcinoma
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- Contribution to journal › Article
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Immunohistochemistry subtyping of urothelial carcinoma is feasible in the daily practice
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- Contribution to journal › Article
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The Urothelial Transcriptomic Response to Interferon Gamma : Implications for Bladder Cancer Prognosis and Immunotherapy
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- Contribution to journal › Article
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Restoring tumor immunogenicity with dendritic cell reprogramming
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- Contribution to journal › Published meeting abstract
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Urostomal ileal conduit complications in association with abdominal wall mesh implantation
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- Contribution to journal › Article
- 2021
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Tumor Subtyping : Making Sense of Heterogeneity with a Goal Toward Treatment
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- Contribution to journal › Scientific review
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Association Between Estrogen Receptors and GATA3 in Bladder Cancer : A Systematic Review and Meta-Analysis of Their Clinicopathological Significance
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- Contribution to journal › Scientific review
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When the Molecular Subtype Is Hidden Behind a Veil of Stroma
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- Contribution to journal › Debate/Note/Editorial
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An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer
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- Contribution to journal › Article
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multiclassPairs: An R package to train multiclass pair-based classifier
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- Contribution to journal › Debate/Note/Editorial
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Stage-stratified molecular profiling of non-muscle-invasive bladder cancer enhances biological, clinical, and therapeutic insight
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- Contribution to journal › Article
- 2020
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Molecular changes during progression from nonmuscle invasive to advanced urothelial carcinoma
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- Contribution to journal › Article
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A Consensus Molecular Classification of Muscle-invasive Bladder Cancer
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- Contribution to journal › Article
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Re : A. Gordon Robertson, Clarice S. Groeneveld, Brian Jordan, et al. Identification of Differential Tumor Subtypes of T1 Bladder Cancer. Eur Urol. In press. http://doi.org/10.1016/j.eururo.2020.06.048
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- Contribution to journal › Letter
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Mark
Recurring urothelial carcinomas show genomic rearrangements incompatible with a direct relationship
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- Contribution to journal › Article
- 2019
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Activin receptor-like kinase 1 is associated with immune cell infiltration and regulates CLEC14A transcription in cancer
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- Contribution to journal › Article
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Molecular profiling in muscle-invasive bladder cancer : more than the sum of its parts
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- Contribution to journal › Scientific review
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Re : Tuan Zea Tan, Mathieu Rouanne, Kien Thiam Tan, Ruby Yun-Ju Huang, Jean-Paul Thiery. Molecular Subtypes of Urothelial Bladder Cancer: Results from a Meta-cohort Analysis of 2411 Tumors. Eur Urol 2019;75:423–32
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- Contribution to journal › Letter
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Intratumoral Heterogeneity of Bladder Cancer by Molecular Subtypes and Histologic Variants
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- Contribution to journal › Article
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Molecular pathology of the luminal class of urothelial tumors
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- Contribution to journal › Article
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Molecular subtypes applied to a population-based modern cystectomy series do not predict cancer-specific survival
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- Contribution to journal › Article
- 2018
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Low Frequency of Intratumor Heterogeneity in Bladder Cancer Tissue Microarrays
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- Contribution to journal › Article
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Molecular Characterization of Bladder Cancer Subtypes
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- Thesis › Doctoral thesis (compilation)
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Molecular subtype classification of urothelial carcinoma in Lynch syndrome
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- Contribution to journal › Article
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FGFR3 mutation increases bladder tumourigenesis by suppressing acute inflammation
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- Contribution to journal › Article
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TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells
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- Contribution to journal › Article
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A validation and extended description of the Lund taxonomy for urothelial carcinoma using the TCGA cohort
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- Contribution to journal › Article
- 2017
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HER2 and EGFR amplification and expression in urothelial carcinoma occurs in distinct biological and molecular contexts
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- Contribution to journal › Article
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Molecular classification of urothelial carcinoma : global mRNA classification versus tumour-cell phenotype classification
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- Contribution to journal › Article
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Impact of Molecular Subtypes in Muscle-invasive Bladder Cancer on Predicting Response and Survival after Neoadjuvant Chemotherapy
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- Contribution to journal › Article
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Frequent miRNA-convergent fusion gene events in breast cancer
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- Contribution to journal › Article
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Re : Thomas Powles, Robert A. Huddart, Tony Elliott, et al. Phase III, Double-blind, Randomized Trial that Compared Maintenance Lapatinib versus Placebo after First-line Chemotherapy in Patients with Human Epidermal Growth Factor Receptor 1/2-positive Metastatic Bladder Cancer. J Clin Oncol 2017;35:48-55. Knowing HER2 Status is Not Enough: A Molecular Subtype Approach to Bladder
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- Contribution to journal › Debate/Note/Editorial
- 2016
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Comprehensive Transcriptional Analysis of Early-Stage Urothelial Carcinoma
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- Contribution to journal › Article
- 2015
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Integrative epigenomic analysis of differential DNA methylation in urothelial carcinoma.
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- Contribution to journal › Article
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Biological determinants of bladder cancer gene expression subtypes.
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- Contribution to journal › Article
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Heterogeneous Challenges for Urologic Cancers.
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- Contribution to journal › Debate/Note/Editorial
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A Molecular Pathologic Framework for Risk Stratification of Stage T1 Urothelial Carcinoma.
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- Contribution to journal › Article
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Molecular subtypes of urothelial carcinoma are defined by specific gene regulatory systems.
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- Contribution to journal › Article
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On Molecular Classification of Bladder Cancer: Out of One, Many.
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- Contribution to journal › Debate/Note/Editorial
- 2014
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Infiltration of CD3(+) and CD68(+) cells in bladder cancer is subtype specific and affects the outcome of patients with muscle-invasive tumors.
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- Contribution to journal › Article
- 2013
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Detailed Analysis of Focal Chromosome Arm 1q and 6p Amplifications in Urothelial Carcinoma Reveals Complex Genomic Events on 1q, and SOX4 as a Possible Auxiliary Target on 6p.
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- Contribution to journal › Article
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Toward a Molecular Pathologic Classification of Urothelial Carcinoma.
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- Contribution to journal › Article
- 2012
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DNA methylation analyses of urothelial carcinoma reveal distinct epigenetic subtypes and an association between gene copy number and methylation status.
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- Contribution to journal › Article
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A Molecular Taxonomy for Urothelial Carcinoma.
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- Contribution to journal › Article
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The Importance of Being Grade 3: WHO 1999 Versus WHO 2004 Pathologic Grading.
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- Contribution to journal › Article
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The bladder cancer genome; chromosomal changes as prognostic makers, opportunities, and obstacles.
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- Contribution to journal › Article
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Integrated genomic and gene expression profiling identifies two major genomic circuits in urothelial carcinoma.
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- Contribution to journal › Article
- 2008
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Non-negative matrix factorization for the analysis of complex gene expression data : Identification of clinically relevant tumor subtypes
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- Contribution to journal › Article