Sven Påhlman (Former)
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- 2023
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Mark
Cytoplasmic HIF-2α as tissue biomarker to identify metastatic sympathetic paraganglioma
(
- Contribution to journal › Article
- 2020
-
Mark
Therapeutic targeting of KSP in preclinical models of high-risk neuroblastoma
(
- Contribution to journal › Article
-
Mark
Integrative discovery of treatments for high-risk neuroblastoma
(
- Contribution to journal › Article
-
Mark
ARNT-dependent HIF-2 transcriptional activity is not sufficient to regulate downstream target genes in neuroblastoma
(
- Contribution to journal › Article
-
Mark
Inflammatory macrophage derived TNFα downregulates estrogen receptor α via FOXO3a inactivation in human breast cancer cells
(
- Contribution to journal › Article
- 2019
-
Mark
ALK positively regulates MYCN activity through repression of HBP1 expression
(
- Contribution to journal › Article
- 2018
-
Mark
Promoter-associated proteins of EPAS1 identified by enChIP-MS – A putative role of HDX as a negative regulator
(
- Contribution to journal › Article
-
Mark
Patient-derived xenograft models reveal intratumor heterogeneity and temporal stability in neuroblastoma
(
- Contribution to journal › Article
-
Mark
Hypoxia and hypoxia-inducible factors in neuroblastoma
(
- Contribution to journal › Article
-
Mark
Refined control of cell stemness allowed animal evolution in the oxic realm
(
- Contribution to journal › Scientific review
-
Mark
A Novel Topical PPAR 3 Agonist Induces PPAR 3 Activity in Ulcerative Colitis Mucosa and Prevents and Reverses Inflammation in Induced Colitis Models
(
- Contribution to journal › Article
- 2017
-
Mark
Hypoxia, pseudohypoxia and cellular differentiation
(
- Contribution to journal › Article
-
Mark
No reason to reconsider HIF-2 as an oncogene in neuroblastoma and other cancer forms
2017) In Proceedings of the National Academy of Sciences of the United States of America 114(51). p.10856-10858(
- Contribution to journal › Letter
-
Mark
Neuroblastoma patient-derived xenograft cells cultured in stem-cell promoting medium retain tumorigenic and metastatic capacities but differentiate in serum
(
- Contribution to journal › Article
-
Mark
Myc-induced glutaminolysis bypasses HIF-driven glycolysis in hypoxic small cell lung carcinoma cells
(
- Contribution to journal › Article
-
Mark
Hypoxia and Cancer Stem Cell Regulation
2017) p.101-126(
- Chapter in Book/Report/Conference proceeding › Book chapter
- 2016
-
Mark
Cancer-associated fibroblast-secreted CXCL16 attracts monocytes to promote stroma activation in triple-negative breast cancers
(
- Contribution to journal › Article
-
Mark
Therapeutic targeting of hypoxia and hypoxia-inducible factors in cancer
(
- Contribution to journal › Scientific review
-
Mark
Extracellular matrix composition defines an ultra-high-risk group of neuroblastoma within the high-risk patient cohort
(
- Contribution to journal › Article
-
Mark
Neuroblastoma patient-derived orthotopic xenografts reflect the microenvironmental hallmarks of aggressive patient tumours
(
- Contribution to journal › Article
-
Mark
HIF2α contributes to antiestrogen resistance via positive bilateral crosstalk with EGFR in breast cancer cells.
(
- Contribution to journal › Article
- 2015
-
Mark
Differential HIF-1α and HIF-2α Expression in Mammary Epithelial Cells during Fat Pad Invasion, Lactation, and Involution.
(
- Contribution to journal › Article
-
Mark
The activation loop tyrosine 823 is essential for the transforming capacity of the c-Kit oncogenic mutant D816V.
(
- Contribution to journal › Article
-
Mark
Differential regulation of HIF-1α and HIF-2α in neuroblastoma: Estrogen-related receptor alpha (ERRα) regulates HIF2A transcription and correlates to poor outcome.
(
- Contribution to journal › Article
-
Mark
Neuroblastoma Patient-Derived Orthotopic Xenografts Retain Metastatic Patterns and Geno- and Phenotypes of Patient Tumours.
(
- Contribution to journal › Article
-
Mark
PI3K-mTORC2 but not PI3K-mTORC1 Regulates Transcription of HIF2A/EPAS1 and Vascularization in Neuroblastoma.
(
- Contribution to journal › Article
-
Mark
Individual patient risk stratification of high-risk neuroblastomas using a two-gene score suited for clinical use.
(
- Contribution to journal › Article
- 2014
-
Mark
Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments.
(
- Contribution to journal › Article
-
Mark
TLX activates MMP-2, promotes self-renewal of tumor spheres in neuroblastoma and correlates with poor patient survival.
(
- Contribution to journal › Article
-
Mark
The PI3-kinase isoform p110δ is essential for cell transformation induced by the D816V mutant of c-Kit in a lipid-kinase-independent manner.
(
- Contribution to journal › Article
-
Mark
EPO-independent functional EPO receptor in breast cancer enhances estrogen receptor activity and promotes cell proliferation.
(
- Contribution to journal › Article
- 2013
-
Mark
The tyrosine kinase CSK associates with FLT3 and c-Kit receptors and regulates downstream signaling.
(
- Contribution to journal › Article
-
Mark
Quantitative Proteomics Profiling of Primary Lung Adenocarcinoma Tumors Reveals Functional Perturbations in Tumor Metabolism
(
- Contribution to journal › Article
-
Mark
MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells
(
- Contribution to journal › Article
-
Mark
HIF2A and IGF2 Expression Correlates in Human Neuroblastoma Cells and Normal Immature Sympathetic Neuroblasts.
(
- Contribution to journal › Article
-
Mark
snoRNPs Regulate Telomerase Activity in Neuroblastoma and Are Associated with Poor Prognosis.
(
- Contribution to journal › Article
- 2012
-
Mark
HIF-2α Expression Is Suppressed in SCLC Cells, Which Survive in Moderate and Severe Hypoxia When HIF-1α Is Repressed.
(
- Contribution to journal › Article
-
Mark
Cancer cell differentiation heterogeneity and aggressive behavior in solid tumors.
(
- Contribution to journal › Article
-
Mark
Tumor-initiating cells in childhood neuroblastoma : Letter
(
- Contribution to journal › Letter
-
Mark
Neuroblastoma: Role of hypoxia and hypoxia inducible factors in tumor progression
2012) 1st edition, XXVI.(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Hypoxic conditions induce a cancer-like phenotype in human breast epithelial cells.
(
- Contribution to journal › Article
- 2011
-
Mark
Neuroblastoma research progress - A 2011 perspective
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Prognostic Value of SOX2 Expression in Neuroblastoma
(
- Contribution to journal › Letter
-
Mark
High nuclear RBM3 expression is associated with an improved prognosis in colorectal cancer
(
- Contribution to journal › Article
-
Mark
Hunting for Protein Markers of Hypoxia by Combining Plasma Membrane Enrichment with a New Approach to Membrane Protein Analysis
(
- Contribution to journal › Article
-
Mark
Neuroblastoma aggressiveness in relation to sympathetic neuronal differentiation stage.
(
- Contribution to journal › Article
-
Mark
JAG2 induction in hypoxic tumor cells alters Notch signaling and enhances endothelial cell tube formation.
(
- Contribution to journal › Article
- 2010
-
Mark
MYCN-regulated microRNAs repress estrogen receptor-{alpha} (ESR1) expression and neuronal differentiation in human neuroblastoma.
(
- Contribution to journal › Article
-
Mark
The HIF-2alpha-Driven Pseudo-Hypoxic Phenotype in Tumor Aggressiveness, Differentiation, and Vascularization.
(
- Chapter in Book/Report/Conference proceeding › Book chapter
- 2009
-
Mark
HIF-1{alpha} and HIF-2{alpha} Are Differentially Regulated In vivo in Neuroblastoma: High HIF-1{alpha} Correlates Negatively to Advanced Clinical Stage and Tumor Vascularization.
(
- Contribution to journal › Article
-
Mark
HIF-2 alpha maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells
(
- Contribution to journal › Article
-
Mark
HIF-1alpha induces MXI1 by alternate promoter usage in human neuroblastoma cells.
(
- Contribution to journal › Article
-
Mark
Effects of hypoxia on small cell lung carcinoma cells
(
- Contribution to journal › Published meeting abstract
-
Mark
Erythropoietin Receptor Expression and Correlation to Tamoxifen Response and Prognosis in Breast Cancer.
(
- Contribution to journal › Article
-
Mark
Arsenic trioxide is highly cytotoxic to small cell lung carcinoma cells.
(
- Contribution to journal › Article
-
Mark
Nuclear expression of the RNA-binding protein RBM3 is associated with an improved clinical outcome in breast cancer.
2009) In Modern Pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 22. p.1564-1574(
- Contribution to journal › Article
- 2008
-
Mark
Hypoxia-inducible factor-2alpha correlates to distant recurrence and poor outcome in invasive breast cancer.
(
- Contribution to journal › Article
-
Mark
Differentiation induced by physiological and pharmacological stimuli leads to increased antigenicity of human neuroblastoma cells
(
- Contribution to journal › Article
-
Mark
High levels of HIF-2alpha highlight an immature neural crest-like neuroblastoma cell cohort located in a perivascular niche.
(
- Contribution to journal › Article
-
Mark
Stem cell factor induces HIF-1alpha at normoxia in hematopoietic cells.
(
- Contribution to journal › Article
-
Mark
High Myc pathway activity and low stage of neuronal differentiation associate with poor outcome in neuroblastoma.
(
- Contribution to journal › Article
-
Mark
Transcriptional adaptation of neuroblastoma cells to hypoxia.
(
- Contribution to journal › Article
-
Mark
Hypoxia-mediated induction of the polyamine system provides opportunities for tumor growth inhibition by combined targeting of vascular endothelial growth factor and ornithine decarboxylase.
(
- Contribution to journal › Article
-
Mark
Binomial mitotic segregation of MYCN-carrying double minutes in neuroblastoma illustrates the role of randomness in oncogene amplification.
(
- Contribution to journal › Article
- 2007
-
Mark
Arsenic trioxide-induced neuroblastoma cell death is accompanied by proteolytic activation of nuclear Bax.
(
- Contribution to journal › Article
-
Mark
Combined IFN-gamma and retinoic acid treatment targets the N-Myc/Max/Mad1 network resulting in repression of N-Myc target genes in MYCN-amplified neuroblastoma cells
(
- Contribution to journal › Article
-
Mark
Arsenic trioxide and neuroblastoma cytotoxicity.
(
- Contribution to journal › Scientific review
-
Mark
Hypoxia inducible factor-2alpha in cancer.
(
- Contribution to journal › Article
-
Mark
Localization of immunoreactive HIF-1alpha and HIF-2alpha in neuroendocrine cells of both benign and malignant prostate glands.
(
- Contribution to journal › Article
-
Mark
From critters to cancers: bridging comparative and clinical research on oxygen sensing, HIF signaling, and adaptations towards hypoxia
(
- Contribution to journal › Article
-
Mark
Neuroblastoma as an experimental model for neuronal differentiation and hypoxia-induced tumor cell dedifferentiation.
(
- Contribution to journal › Scientific review
- 2006
-
Mark
Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes
(
- Contribution to journal › Article
-
Mark
Recruitment of HIF-1alpha and HIF-2alpha to common target genes is differentially regulated in neuroblastoma: HIF-2alpha promotes an aggressive phenotype.
(
- Contribution to journal › Article
-
Mark
Translocation-excision-deletion-amplification mechanism leading to nonsyntenic coamplification of MYC and ATBF1
(
- Contribution to journal › Article
-
Mark
Effect of hypoxia on the tumor phenotype: the neuroblastoma and breast cancer models
(
- Chapter in Book/Report/Conference proceeding › Paper in conference proceeding
- 2005
-
Mark
Phenotypic persistence after reoxygenation of hypoxic neuroblastoma cells.
(
- Contribution to journal › Article
-
Mark
ERK1/2 inhibition increases antiestrogen treatment efficacy by interfering with hypoxia-induced downregulation of ERalpha: a combination therapy potentially targeting hypoxic and dormant tumor cells.
(
- Contribution to journal › Article
-
Mark
Multidrug-resistant neuroblastoma cells are responsive to arsenic trioxide at both normoxia and hypoxia.
(
- Contribution to journal › Article
-
Mark
Positional and functional mapping of a neuroblastoma differentiation gene on chromosome 11
(
- Contribution to journal › Article
-
Mark
Hypoxia-induced dedifferentiation of tumor cells - A mechanism behind heterogeneity and aggressiveness of solid tumors.
(
- Contribution to journal › Scientific review
-
Mark
HIF-2alpha expression in human fetal paraganglia and neuroblastoma: relation to sympathetic differentiation, glucose deficiency, and hypoxia.
(
- Contribution to journal › Article
- 2004
-
Mark
Induction of ID2 expression by hypoxia-inducible factor-1: ARole in dedifferentiation of hypoxic neuroblastoma cells.
(
- Contribution to journal › Article
-
Mark
Arsenic trioxide-induced death of neuroblastoma cells involves activation of Bax and does not require p53.
(
- Contribution to journal › Article
-
Mark
Human neuroblastoma cells exposed to hypoxia: induction of genes associated with growth, survival, and aggressive behavior.
(
- Contribution to journal › Article
-
Mark
Neuroblastoma cells with overexpressed MYCN retain their capacity to undergo neuronal differentiation.
(
- Contribution to journal › Article
-
Mark
Ubiquilin-1 is a novel HASH-1-complexing protein that regulates levels of neuronal bHLH transcription factors in human neuroblastoma cells.
(
- Contribution to journal › Article
-
Mark
Notch signaling in neuroblastoma.
(
- Contribution to journal › Article
-
Mark
Erythropoietin enhances response to treatment in patients with advanced breast cancer
(
- Contribution to journal › Debate/Note/Editorial
- 2003
-
Mark
ID2 expression in neuroblastoma does not correlate to MYCN levels and lacks prognostic value
(
- Contribution to journal › Article
-
Mark
Expression of trkB in Human Neuroblastoma in Relation to MYCN Expression and Retinoic Acid Treatment.
(
- Contribution to journal › Article
-
Mark
Regional cyclin D1 overexpression or hypoxia correlate inversely with heterogeneous oestrogen receptor-alpha expression in human breast cancer.
(
- Contribution to journal › Article
-
Mark
Hypoxia promotes a dedifferentiated phenotype in ductal breast carcinoma in situ.
(
- Contribution to journal › Article
-
Mark
Hypoxia-induced dedifferentiation in neuroblastoma cells.
(
- Contribution to journal › Article
- 2002
-
Mark
Hypoxia alters gene expression in human neuroblastoma cells toward an immature and neural crest-like phenotype.
(
- Contribution to journal › Article
-
Mark
Modulation of Basic Helix-Loop-Helix Transcription Complex Formation by Id Proteins during Neuronal Differentiation.
(
- Contribution to journal › Article
-
Mark
Protein Kinase Cepsilon Actin-binding Site Is Important for Neurite Outgrowth during Neuronal Differentiation.
(
- Contribution to journal › Article
- 2001
-
Mark
Interferon-gamma cooperates with retinoic acid and phorbol ester to induce differentiation and growth inhibition of human neuroblastoma cells
(
- Contribution to journal › Article
-
Mark
Differences in early and late responses between neurotrophin-stimulated trkA- and trkC-transfected SH-SY5Y neuroblastoma cells
(
- Contribution to journal › Article
- 2000
-
Mark
HASH-1 and E2-2 are expressed in human neuroblastoma cells and form a functional complex
(
- Contribution to journal › Article
-
Mark
Patched 2, located in 1p32-34, is not mutated in high stage neuroblastoma tumors
(
- Contribution to journal › Article
-
Mark
Arsenic trioxide inhibits neuroblastoma growth in vivo and promotes apoptotic cell death in vitro
(
- Contribution to journal › Article
- 1999
-
Mark
The basic helix-loop-helix transcription factor dHAND, a marker gene for the developing human sympathetic nervous system, is expressed in both high- and low-stage neuroblastomas
(
- Contribution to journal › Article
-
Mark
PKCepsilon, via its regulatory domain and independently of its catalytic domain, induces neurite-like processes in neuroblastoma cells
(
- Contribution to journal › Article
-
Mark
Human achaete-scute homologue 1 (HASH-1) is downregulated in differentiating neuroblastoma cells
(
- Contribution to journal › Article
-
Mark
Novel and classical protein kinase C isoforms have different functions in proliferation, survival and differentiation of neuroblastoma cells
(
- Contribution to journal › Article