Laurent Roybon (Former)
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- 2023
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Mark
Cellular Aging Secretes : a Comparison of Bone-Marrow-Derived and Induced Mesenchymal Stem Cells and Their Secretome Over Long-Term Culture
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- Contribution to journal › Article
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Mark
Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer's disease pathogenesis
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- Contribution to journal › Article
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Mark
Human iPSC-derived microglia carrying the LRRK2-G2019S mutation show a Parkinson’s disease related transcriptional profile and function
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- Contribution to journal › Article
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Mark
Inhibition of the serine protease HtrA1 by SerpinE2 suggests an extracellular proteolytic pathway in the control of neural crest migration
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- Contribution to journal › Article
- 2022
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Mark
Parkinson's disease and multiple system atrophy patient iPSC-derived oligodendrocytes exhibit alpha-synuclein-induced changes in maturation and immune reactive properties
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- Contribution to journal › Article
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Mark
Canonical Bone Morphogenetic Protein Signaling Regulates Expression of Aquaporin-4 and Its Anchoring Complex in Mouse Astrocytes
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- Contribution to journal › Article
- 2021
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Mark
Generation of the human pluripotent stem-cell-derived astrocyte model with forebrain identity
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- Contribution to journal › Article
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Mark
TNF-α and α-synuclein fibrils differently regulate human astrocyte immune reactivity and impair mitochondrial respiration
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- Contribution to journal › Article
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Mark
The intracellular milieu of Parkinson’s disease patient brain cells modulates alpha-synuclein protein aggregation
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- Contribution to journal › Article
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Mark
Urokinase plasminogen activator mediates changes in human astrocytes modeling fragile X syndrome
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- Contribution to journal › Article
- 2020
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Mark
NF-E2-related factor 2 activation boosts antioxidant defenses and ameliorates inflammatory and amyloid properties in human Presenilin-1 mutated Alzheimer's disease astrocytes
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- Contribution to journal › Article
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Mark
Unique signatures of stress-induced senescent human astrocytes
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- Contribution to journal › Article
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Mark
Human iPSC-Derived Hippocampal Spheroids : An Innovative Tool for Stratifying Alzheimer Disease Patient-Specific Cellular Phenotypes and Developing Therapies
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- Contribution to journal › Article
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Mark
Demonstration of brain region-specific neuronal vulnerability in human iPSC-based model of familial Parkinson's disease
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- Contribution to journal › Article
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Mark
Generation of an induced pluripotent stem cell line (CSC-32) from a patient with Parkinson's disease carrying a heterozygous variation p.A53T in the SNCA gene
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- Contribution to journal › Article
- 2019
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Mark
Generation of an induced pluripotent stem cell line (CSC-46) from a patient with Parkinson's disease carrying a novel p.R301C mutation in the GBA gene
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- Contribution to journal › Article
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Mark
PARK2 mutation causes metabolic disturbances and impaired survival of human iPSC-derived neurons
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- Contribution to journal › Article
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Mark
FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes
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- Contribution to journal › Article
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Mark
Cellular alterations identified in pluripotent stem cell-derived midbrain spheroids generated from a female patient with progressive external ophthalmoplegia and parkinsonism who carries a novel variation (p.Q811R) in the POLG1 gene
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- Contribution to journal › Article
- 2018
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Mark
Parkin absence accelerates microtubule aging in dopaminergic neurons
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- Contribution to journal › Article
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Mark
Early postnatal behavioral, cellular, and molecular changes in models of Huntington disease are reversible by HDAC inhibition
2018) In Proceedings of the National Academy of Sciences of the United States of America 115(37). p.8765-8774(
- Contribution to journal › Article
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Mark
Generation of an induced pluripotent stem cell line (CSC-41) from a Parkinson's disease patient carrying a p.G2019S mutation in the LRRK2 gene
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- Contribution to journal › Article
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Mark
Generation of an induced pluripotent stem cell line (CSC-44) from a Parkinson's disease patient carrying a compound heterozygous mutation (c.823C > T and EX6 del) in the PARK2 gene
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- Contribution to journal › Article
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Mark
Generation of a human induced pluripotent stem cell line (CSC-40) from a Parkinson's disease patient with a PINK1 p.Q456X mutation
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- Contribution to journal › Article
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Mark
Generation of an integration-free induced pluripotent stem cell line (CSC-43J) from a patient with sporadic Parkinson's disease
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- Contribution to journal › Article
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Mark
Generation of a human induced pluripotent stem cell line (CSC-42) from a patient with sporadic form of Parkinson's disease
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- Contribution to journal › Article
- 2017
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Mark
Memory formation orchestrates the wiring of adult-born hippocampal neurons into brain circuits
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- Contribution to journal › Article
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Mark
Amplifying mitochondrial function rescues adult neurogenesis in a mouse model of Alzheimer's disease
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- Contribution to journal › Article
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Mark
Reporting on methods to generate and purify rodent and human oligodendrocytes from different sources
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- Contribution to journal › Article
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Mark
Human astrocytes transfer aggregated alpha-synuclein via tunneling nanotubes
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- Contribution to journal › Article
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Mark
Differential alteration of hippocampal function and plasticity in females and males of the APPxPS1 mouse model of Alzheimer's disease
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- Contribution to journal › Article
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Mark
Derivation of mouse embryonic stem cell lines from tyrosine hydroxylase reporter mice crossed with a human SNCA transgenic mouse model of Parkinson's disease
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- Contribution to journal › Article
- 2016
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Mark
Label-free concentration of viable neurons, hESCs and cancer cells by means of acoustophoresis.
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- Contribution to journal › Article
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Mark
α-Synuclein is a Novel Microtubule Dynamase
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- Contribution to journal › Article
- 2015
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Mark
The Origin, Development and Molecular Diversity of Rodent Olfactory Bulb Glutamatergic Neurons Distinguished by Expression of Transcription Factor NeuroD1.
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- Contribution to journal › Article
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Mark
Generation of human pluripotent stem cell reporter lines for the isolation of and reporting on astrocytes generated from ventral midbrain and ventral spinal cord neural progenitors.
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- Contribution to journal › Article
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Mark
Genetic manipulation of adult-born hippocampal neurons rescues memory in a mouse model of Alzheimer's disease.
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- Contribution to journal › Article
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Mark
Alpha-Synuclein Expression in the Oligodendrocyte Lineage: an In Vitro and In Vivo Study Using Rodent and Human Models.
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- Contribution to journal › Article
- 2014
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Mark
Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats.
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- Contribution to journal › Article
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Mark
Gene Profiling of Human Induced Pluripotent Stem Cell-Derived Astrocyte Progenitors Following Spinal Cord Engraftment.
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- Contribution to journal › Article
- 2013
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Mark
Modifications of Hippocampal Circuits and Early Disruption of Adult Neurogenesis in the Tg2576 Mouse Model of Alzheimer's Disease
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- Contribution to journal › Article
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Mark
NGF rescues hippocampal cholinergic neuronal markers, restores neurogenesis, and improves the spatial working memory in a mouse model of Huntington's Disease
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- Contribution to journal › Article
- 2012
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Mark
The adult human brain harbors multipotent perivascular mesenchymal stem cells.
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- Contribution to journal › Article
- 2011
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Mark
Neurogenesis In The R6/2 Mouse Model Of Huntington'S Disease Is Impaired At The Level Of Neurod1
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- Contribution to journal › Article
- 2010
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Mark
Brain injury activates microglia that induce neural stem cell proliferation ex vivo and promote differentiation of neurosphere-derived cells into neurons and oligodendrocytes
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- Contribution to journal › Article
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Mark
GABAergic Differentiation Induced by Mash1 Is Compromised by the bHLH Proteins Neurogenin2, NeuroD1, and NeuroD2.
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- Contribution to journal › Article
- 2009
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Mark
BRAIN INJURY ACTIVATES MICROGLIA THAT INDUCE NEURAL STEM CELL PROLIFERATION AND PROMOTE DIFFERENTIATION OF NEUROSPHERE-DERIVED CELLS INTO NEURONS AND TO OLIGODENDROCYTES
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- Contribution to journal › Published meeting abstract
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Mark
Bone Marrow Multipotent Mesenchymal Stroma Cells Act as Pericyte-like Migratory Vehicles in Experimental Gliomas.
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- Contribution to journal › Article
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Mark
Absence of striatal newborn neurons with mature phenotype following defined striatal and cortical excitotoxic brain injuries.
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- Contribution to journal › Article
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Mark
Neurogenin2 directs granule neuroblast production and amplification while NeuroD1 specifies neuronal fate during hippocampal neurogenesis.
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- Contribution to journal › Article