Division of Molecular Medicine and Gene Therapy
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- 2021
-
Human radical scavenger α1-microglobulin protects against hemolysis in vitro and α1-microglobulin knockout mice exhibit a macrocytic anemia phenotype
Kristiansson, Amanda LU ; Bergwik, Jesper LU ; Alattar, Abdul Ghani LU
; Flygare, Johan
LU
; Gram, Magnus
LU
; Hansson, Stefan R
LU
; Olsson, Martin L
LU
; Storry, Jill R
LU
; Allhorn, Maria
LU
and Åkerström, Bo
LU
(2021)
In Free Radical Biology & Medicine
162.
Mark
- Correction of pathology in mice displaying Gaucher disease type 1 by a clinically-applicable lentiviral vector
-
Ontogenic shifts in cellular fate are linked to proteotype changes in lineage-biased hematopoietic progenitor cells
Jassinskaja, Maria LU ; Pimková, Kristýna LU ; Arh, Nejc LU ; Johansson, Emil LU
; Davoudi, Mina
LU
; Pereira, Carlos Filipe
LU
; Sitnicka, Ewa
LU
and Hansson, Jenny
LU
(2021)
In Cell Reports
34(12).
Mark
- Genome-wide association study on 13,167 individuals identifies regulators of hematopoietic stem and progenitor cell levels in human blood
-
Human Primary Airway Basal Cells Display a Continuum of Molecular Phases from Health to Disease in COPD
Wijk, Sofia C LU ; Prabhala, Pavan LU ; Michaliková, Barbora LU ; Sommarin, Mikael LU ; Doyle, Alexander LU ; Lang, Stefan LU
; Kanzenbach, Karina
LU
; Tufvesson, Ellen
LU
; Lindstedt, Sandra
LU
and Leigh, Nicholas D
LU
, et al.
(2021)
In American Journal of Respiratory Cell and Molecular Biology
Mark
-
BCAT1 decreases the sensitivity of cancer cells to cisplatin by regulating mTOR-mediated autophagy via branched-chain amino acid metabolism
Luo, Lifang ; Sun, Wenjing ; Zhu, Weijian ; Li, Shuhan ; Zhang, Wenqi ; Xu, Xiaohui ; Fang, Daoquan ; Grahn, Tan Hooi Min LU
; Jiang, Lei
and Zheng, Yihu
(2021)
In Cell Death and Disease
12(2).
Mark
-
Isolation of high yield and quality RNA from human precision-cut lung slices for RNA-sequencing and computational integration with larger patient cohorts
Stegmayr, John LU ; Alsafadi, Hani N LU
; Langwinski, Wojciech
LU
; Niroomand, Anna
LU
; Lindstedt, Sandra
LU
; Leigh, Nicholas D
LU
and Wagner, Darcy E
LU
(2021)
In American Journal of Physiology: Lung Cellular and Molecular Physiology
320(2).
p.232-240
Mark
- Mitochondrial Potentiation Ameliorates Age-Related Heterogeneity in Hematopoietic Stem Cell Function
- Gene therapy for infantile malignant osteopetrosis : review of pre-clinical research and proof-of-concept for phenotypic reversal
-
Hypoxia-induced alpha-globin expression in syncytiotrophoblasts mimics the pattern observed in preeclamptic placentas
Masoumi, Zahra LU
; Erlandsson, Lena
LU
; Hansson, Eva
LU
; Magnusson, Mattias
LU
; Mezey, Eva
and Hansson, Stefan R.
LU
(2021)
In International Journal of Molecular Sciences
22(7).
Mark