Hematopoietic Stem Cell Development

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2024
Mark Hematopoietic cells emerging from hemogenic endothelium exhibit lineage-specific oxidative stress responses
Biezeman, Harmke ; Nubiè, Martina and Oburoglu, Leal ^LU (2024) In Journal of Biological Chemistry 300(11).
- Contribution to journal › Article
2023
Mark Ciclopirox Ethanolamine Preserves the Immature State of Human HSCs by Mediating Intracellular Iron Content
Safaee Talkhoncheh, Mehrnaz ^LU ; Baudet, Aurélie ^LU ; Ek, Fredrik ^LU ; Subramaniam, Agatheeswaran ^LU ; Kao, Yun-Ruei ; Miharada, Natsumi ^LU ; Karlsson, Christine ^LU ; Oburoglu, Leal ^LU ; Rydström, Anna ^LU and Žemaitis, Kristijonas ^LU , et al. (2023) In Blood Advances 7(24). p.7407-7417
- Contribution to journal › Article
Mark Combined GLUT1 and OXPHOS inhibition eliminates acute myeloid leukemia cells by restraining their metabolic plasticity
Rodriguez-Zabala, Maria ^LU ; Ramakrishnan, Ramprasad ^LU ; Reinbach, Katrin ^LU ; Ghosh, Somadri ^LU ; Oburoglu, Leal ^LU ; Falqués-Costa, Antoni ; Bellamkonda, Kishan ^LU ; Ehinger, Mats ^LU ; Peña-Martínez, Pablo ^LU and Puente-Moncada, Noelia ^LU , et al. (2023) In Blood Advances 7(18). p.5382-5395
- Contribution to journal › Article
Mark Astrocyte dysfunction and neuronal network hyperactivity in a CRISPR engineered pluripotent stem cell model of frontotemporal dementia
Canals, Isaac ^LU ; Comella-Bolla, Andrea ^LU ; Cepeda-Prado, Efrain ^LU ; Avaliani, Natalia ^LU ; Crowe, James A ^LU ; Oburoglu, Leal ^LU ; Bruzelius, Andreas ^LU ; King, Naomi ^LU ; Pajares, María A and Pérez-Sala, Dolores , et al. (2023) In Brain Communications 5(3). p.1-16
- Contribution to journal › Article
2022
Mark Pyruvate metabolism guides definitive lineage specification during hematopoietic emergence
Oburoglu, Leal ^LU ; Mansell, Els ^LU ; Canals, Isaac ^LU ; Sigurdsson, Valgardur ^LU ; Guibentif, Carolina ^LU ; Soneji, Shamit ^LU and Woods, Niels Bjarne ^LU (2022) In EMBO Reports 23(2).
- Contribution to journal › Article
Mark FOXO1 regulates pentose phosphate pathway-mediated induction of developmental erythropoiesis
Monsalve, Anuntxi ; Canals, Isaac ^LU and Oburoglu, Leal ^LU (2022) In Frontiers in Cell and Developmental Biology 10.
- Contribution to journal › Article
Mark Site-specific CRISPR-based mitochondrial DNA manipulation is limited by gRNA import
Schmiderer, Ludwig ^LU ; Yudovich, David ^LU ; Oburoglu, Leal ^LU ; Hjort, Martin ^LU and Larsson, Jonas ^LU (2022) In Scientific Reports 12. p.1-9
- Contribution to journal › Article
2021
Mark Glutamine metabolism regulates endothelial to hematopoietic transition and hematopoietic lineage specification
Oburoglu, Leal ^LU ; Mansell, Els ^LU and Woods, Niels Bjarne ^LU (2021) In Scientific Reports 11(1).
- Contribution to journal › Article
2020
Mark Generation of gene-corrected functional osteoclasts from osteopetrotic induced pluripotent stem cells
Xian, Xiaojie ^LU ; Moraghebi, Roksana ^LU ; Löfvall, Henrik ^LU ; Fasth, Anders ; Henriksen, Kim ; Richter, Johan ^LU ; Woods, Niels Bjarne ^LU and Moscatelli, Ilana ^LU (2020) In Stem Cell Research & Therapy 11.
- Contribution to journal › Article
Mark S100A6 is a critical regulator of hematopoietic stem cells.
Tan Grahn, Hooi Min ^LU ; Niroula, Abhishek ^LU ; Vegvari, Akos ; Oburoglu, Leal ^LU ; Pertesi, Maroulio ^LU ; Warsi, Sarah ^LU ; Safi, Fatemeh ^LU ; Miharada, Natsumi ^LU ; C. Garcia, Sandra ^LU and Siva, Kavitha ^LU , et al. (2020) In Leukemia
- Contribution to journal › Article

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