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- 2023
-
Mark
Reduced volume of diabetic pancreatic islets in rodents detected by synchrotron X-ray phase-contrast microtomography and deep learning network
(
- Contribution to journal › Article
-
Mark
GPR162 is a beta cell CART receptor
(
- Contribution to journal › Article
- 2022
-
Mark
The T-type calcium channel CaV3.2 regulates insulin secretion in the pancreatic β-cell
(
- Contribution to journal › Article
-
Mark
The structure of insulin granule core determines secretory capacity being reduced in type-2 diabetes
2022)(
- Working paper/Preprint › Preprint in preprint archive
-
Mark
A critical role of the mechanosensor PIEZO1 in glucose-induced insulin secretion in pancreatic β-cells
(
- Contribution to journal › Article
-
Mark
Islet Gene View-a tool to facilitate islet research
(
- Contribution to journal › Article
-
Mark
Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets
(
- Contribution to journal › Article
-
Mark
The Calcium Channel Subunit Gamma-4 as a Novel Regulator of MafA in Pancreatic Beta-Cell Controls Glucose Homeostasis
(
- Contribution to journal › Article
-
Mark
Debatt: Sverige måsta satsa på utveckling av nya halvledare
2022) In Dagens Industri(
- Contribution to specialist publication or newspaper › Newspaper article
-
Mark
MAFA and MAFB regulate exocytosis-related genes in human β-cells
(
- Contribution to journal › Article
- 2021
-
Mark
The MafA-target gene PPP1R1A regulates GLP1R-mediated amplification of glucose-stimulated insulin secretion in β-cells
2021) In Metabolism: Clinical and Experimental(
- Contribution to journal › Article
-
Mark
Transcriptional analysis of islets of Langerhans from organ donors of different ages
(
- Contribution to journal › Article
-
Mark
Epigenome-Wide Histone Acetylation Changes in Peripheral Blood Mononuclear Cells in Patients with Type 2 Diabetes and Atherosclerotic Disease
(
- Contribution to journal › Article
-
Mark
Elevated circulating follistatin associates with an increased risk of type 2 diabetes
(
- Contribution to journal › Article
- 2020
-
Mark
The TCF7L2-dependent high-voltage activated calcium channel subunit α2δ-1 controls calcium signaling in rodent pancreatic beta-cells
(
- Contribution to journal › Article
-
Mark
A circular RNA generated from an intron of the insulin gene controls insulin secretion
(
- Contribution to journal › Article
- 2019
-
Mark
Preserving Insulin Secretion in Diabetes by Inhibiting VDAC1 Overexpression and Surface Translocation in β Cells
(
- Contribution to journal › Article
-
Mark
The calcium channel subunit gamma-4 is regulated by MafA and necessary for pancreatic beta-cell specification
(
- Contribution to journal › Article
-
Mark
Complement Component C3 Is Highly Expressed in Human Pancreatic Islets and Prevents β Cell Death via ATG16L1 Interaction and Autophagy Regulation
(
- Contribution to journal › Article
-
Mark
Intracellular cytosolic complement component C3 regulates cytoprotective autophagy in pancreatic beta cells by interaction with ATG16L1
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Defective exocytosis and processing of insulin in a cystic fibrosis mouse model
(
- Contribution to journal › Article
-
Mark
Pancreatic β-cell mRNA modification as a marker for type 2 diabetes
(
- Contribution to journal › Scientific review
-
Mark
A cryptic non-GPI-anchored cytosolic isoform of CD59 controls insulin exocytosis in pancreatic β-cells by interaction with SNARE proteins
2019) In FASEB journal : official publication of the Federation of American Societies for Experimental Biology 33(11). p.12425-12434(
- Contribution to journal › Article
- 2018
-
Mark
Intestinal CART is a regulator of GIP and GLP-1 secretion and expression
(
- Contribution to journal › Article
-
Mark
Intracellular non-GPI anchored isoform of CD59 is responsible for facilitating of insulin secretion from pancreatic beta-cells
(
- Contribution to conference › Abstract
-
Mark
MafA expression preserves immune homeostasis in human and mouse islets
(
- Contribution to journal › Article
- 2017
-
Mark
Loss of a2d-1 calcium channel subunit function increases the susceptibility for diabetes
(
- Contribution to journal › Article
-
Mark
The human serum protein C4b-binding protein inhibits pancreatic IAPP-induced inflammasome activation
(
- Contribution to journal › Article
-
Mark
Regulation of Nuclear Receptor Interacting Protein 1 (NRIP1) Gene Expression in Response to Weight Loss and Exercise in Humans
(
- Contribution to journal › Article
-
Mark
Palmitoylation of Ca2+ channel subunit CaVβ2a induces pancreatic beta-cell toxicity via Ca2+ overload
(
- Contribution to journal › Article
-
Mark
A cryptic non-GPI anchored form of CD59 facilitates insulin secretion from pancreatic beta cells
(
- Contribution to journal › Published meeting abstract
- 2016
-
Mark
MafA-Controlled Nicotinic Receptor Expression Is Essential for Insulin Secretion and Is Impaired in Patients with Type 2 Diabetes.
(
- Contribution to journal › Article
-
Mark
HMGB1 binds to the rs7903146 locus in TCF7L2 in human pancreatic islets.
(
- Contribution to journal › Article
-
Mark
CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion
(
- Contribution to journal › Article
-
Mark
C4b-binding protein protects β-cells from islet amyloid polypeptide-induced cytotoxicity
(
- Contribution to journal › Article
-
Mark
Elevated basal insulin secretion in type 2 diabetes caused by reduced plasma membrane cholesterol
(
- Contribution to journal › Article
- 2015
-
Mark
Complement inhibitor CD55 governs the integrity of membrane rafts in pancreatic beta cells, but plays no role in insulin secretion.
(
- Contribution to journal › Article
-
Mark
Neutrophil Extracellular Traps Induce Trypsin Activation, Inflammation, and Tissue Damage in Mice with Severe Acute Pancreatitis.
(
- Contribution to journal › Article
-
Mark
Pancreatic beta cell dedifferentiation involves the voltage-gated calcium channel subunit gamma4
2015) 51st EASD Annual Meeting of the European Association for the Study of Diabetes In Diabetologia 58(S1). p.208-209(
- Contribution to journal › Published meeting abstract
- 2014
-
Mark
Glioma Cell Proliferation Controlled by ERK Activity-Dependent Surface Expression of PDGFRA.
(
- Contribution to journal › Article
-
Mark
Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism.
(
- Contribution to journal › Article
-
Mark
The Complement Inhibitor CD59 Regulates Insulin Secretion by Modulating Exocytotic Events.
(
- Contribution to journal › Article
-
Mark
Genotype-based treatment of type 2 diabetes with an α2A-adrenergic receptor antagonist.
(
- Contribution to journal › Article
-
Mark
TCF7L2 is a master regulator of insulin production and processing.
(
- Contribution to journal › Article
-
Mark
Dynamic Magnetic Fields Remote-Control Apoptosis via Nanoparticle Rotation.
(
- Contribution to journal › Article
- 2013
-
Mark
Eukaryotic translation initiation factor 3 subunit e controls intracellular calcium homeostasis by regulation of cav1.2 surface expression.
(
- Contribution to journal › Article
-
Mark
The human L-type calcium channel Ca(v)1.3 regulates insulin release and polymorphisms in CACNA1D associate with type 2 diabetes.
(
- Contribution to journal › Article
-
Mark
Effect of Common Genetic Variants Associated with Type 2 Diabetes and Glycemic Traits on α- and β-cell Function and Insulin Action in Man.
(
- Contribution to journal › Article
-
Mark
Expression profiling of cell cycle genes in human pancreatic islets with and without type 2 diabetes.
(
- Contribution to journal › Article
- 2012
-
Mark
The adult human brain harbors multipotent perivascular mesenchymal stem cells.
(
- Contribution to journal › Article
-
Mark
Increased DNA Methylation and Decreased Expression of PDX-1 in Pancreatic Islets from Patients with Type 2 Diabetes.
(
- Contribution to journal › Article
-
Mark
Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes.
(
- Contribution to journal › Article
-
Mark
Impact of transcription factor 7-like 2 (TCF7L2) on pancreatic islet function and morphology in mice and men.
(
- Contribution to journal › Article
-
Mark
Islet amyloid polypeptide triggers limited complement activation and binds complement inhibitor C4b-binding protein, which enhances fibril formation.
(
- Contribution to journal › Article
-
Mark
γ-Aminobutyric acid (GABA) signalling in human pancreatic islets is altered in type 2 diabetes.
(
- Contribution to journal › Article
-
Mark
Reduced Insulin Exocytosis in Human Pancreatic β-cells With Gene Variants Linked to Type 2 Diabetes.
(
- Contribution to journal › Article
-
Mark
Truncated and Full-Length Thioredoxin-1 Have Opposing Activating and Inhibitory Properties for Human Complement with Relevance to Endothelial Surfaces.
(
- Contribution to journal › Article
-
Mark
Role of TCF7L2 risk variant and dietary fibre intake on incident type 2 diabetes.
(
- Contribution to journal › Article
-
Mark
A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.
(
- Contribution to journal › Article
-
Mark
Survival of pancreatic beta cells is partly controlled by a TCF7L2-p53-p53INP1-dependent pathway.
(
- Contribution to journal › Article
- 2011
-
Mark
Survival of rat pancreatic islets is partly controlled by a TCF7L2-p53-p53INP1 dependent pathway
(
- Contribution to journal › Article
- 2010
-
Mark
Complement inhibitor C4b-binding protein (C4BP) binding to islet amyloid polypeptide prevents complement activation and further fibril formation in the endocrine pancreas
(
- Contribution to journal › Published meeting abstract
-
Mark
Polymorphisms in CACNA1D affect insulin release and channel expression and associate with type 2 diabetes
2010) 46th Annual Meeting of the European-Association-for-the- Study-of-Diabetes (EASD) In Diabetologia 53(Suppl. 1). p.296-296(
- Contribution to journal › Published meeting abstract
-
Mark
Complement receptor C5aR is expressed in pancreatic islets and affects glucose-induced insulin and glucagon secretion
2010) 46th Annual Meeting of the European-Association-for-the- Study-of-Diabetes (EASD) In Diabetologia 53(Suppl. 1). p.531-531(
- Contribution to journal › Published meeting abstract
-
Mark
TCF7L2-conferred apoptosis in pancreatic beta cells involves the p53 pathway
2010) 46th Annual Meeting of the European-Association-for-the- Study-of-Diabetes (EASD) In Diabetologia 53(Suppl. 1). p.298-298(
- Contribution to journal › Published meeting abstract
-
Mark
The role of wnt antagonists in impaired beta cell exocytosis
2010) 46th Annual Meeting of the European-Association-for-the- Study-of-Diabetes (EASD) In Diabetologia 53(Suppl. 1). p.91-91(
- Contribution to journal › Published meeting abstract
-
Mark
ClC-3-A Granular Anion Transporter Involved in Insulin Secretion? Response
(
- Contribution to journal › Letter
-
Mark
Enhancement of glucagon secretion in mouse and human pancreatic alpha cells by protein kinase C (PKC) involves intracellular trafficking of PKCalpha and PKCdelta.
(
- Contribution to journal › Article
-
Mark
Molecular Function of TCF7L2: Consequences of TCF7L2 Splicing for Molecular Function and Risk for Type 2 Diabetes.
(
- Contribution to journal › Article
-
Mark
Overexpression of Alpha2A-Adrenergic Receptors Contributes to Type 2 Diabetes.
(
- Contribution to journal › Article
-
Mark
GLP-1 inhibits and adrenaline stimulates glucagon release by differential modulation of N- and L-type Ca2+ channel-dependent exocytosis.
(
- Contribution to journal › Article
-
Mark
The interactions of thioredoxin and the complement system
(
- Contribution to journal › Published meeting abstract
- 2009
-
Mark
The impact of differential splicing of TCF7L2 on target gene expression in human islet of Langerhans
2009) 45th Annual Meeting of the European-Association-for-the-Study-of-Diabetes In Diabetologia 52(Suppl 1). p.78-78(
- Contribution to journal › Published meeting abstract
-
Mark
Rapid changes in surface expression of L-type Cav1.2 channels in stimulated INS-1 cells
2009) 45th Annual Meeting of the European-Association-for-the-Study-of-Diabetes In Diabetologia 52(Suppl. 1). p.436-436(
- Contribution to journal › Published meeting abstract
-
Mark
Evaluation of chloride channel-3 as a potential target for TCF7L2-dependent impairment of insulin secretion
2009) 45th Annual Meeting of the European-Association-for-the-Study-of-Diabetes In Diabetologia 52(Suppl 1). p.332-332(
- Contribution to journal › Published meeting abstract
-
Mark
Complement factors are expressed in pancreatic islets and affect glucose induced insulin secretion
2009) 45th Annual Meeting of the European-Association-for-the-Study-of-Diabetes In Diabetologia 52(Suppl 1). p.455-455(
- Contribution to journal › Published meeting abstract
-
Mark
Bone marrow transplantation stimulates pancreatic β-cell replication after tissue damage.
(
- Contribution to journal › Article
-
Mark
Unique splicing pattern of the TCF7L2 gene in human pancreatic islets.
(
- Contribution to journal › Article
-
Mark
Glutaredoxin-1 mediates NADPH-dependent stimulation of calcium-dependent insulin secretion.
(
- Contribution to journal › Article
-
Mark
Autologous hematopoietic stem cell transplantation in type 1-diabetes.
(
- Contribution to journal › Article
-
Mark
Suppression of sulfonylurea- and glucose-induced insulin secretion in vitro and in vivo in mice lacking the chloride transport protein ClC-3.
(
- Contribution to journal › Article
-
Mark
Hyperactivity in adrenergic signalling via alpha2A receptors contributes to human type 2 diabetes
2009) 45th Annual Meeting of the European-Association-for-the-Study-of-Diabetes In Diabetologia 52(Suppl 1). p.108-108(
- Contribution to journal › Published meeting abstract
- 2008
-
Mark
NADPH as a putative regulator of voltage-gated Ca2+ channels in pancreatic beta cells
2008) 44th EASD Annual Meeting of the European Association for the Study of Diabetes In Diabetologia 51(S1). p.196-196(
- Contribution to journal › Published meeting abstract
-
Mark
Why treatment fails in type 2 diabetes.
(
- Contribution to journal › Article
-
Mark
CAPS1 and CAPS2 Regulate Stability and Recruitment of Insulin Granules in Mouse Pancreatic beta Cells.
(
- Contribution to journal › Article
- 2007
-
Mark
R-type Ca2+-channel-evoked CICR regulates glucose-induced somatostatin secretion
(
- Contribution to journal › Article
-
Mark
Polymorphisms in the gene encoding the voltage-dependent Ca(2+) channel Ca (V)2.3 (CACNA1E) are associated with type 2 diabetes and impaired insulin secretion
(
- Contribution to journal › Article
- 2006
-
Mark
Anaplerosis via pyruvate carboxylase is required for the fuel-induced rise in the ATP:ADP ratio in rat pancreatic islets.
(
- Contribution to journal › Article
-
Mark
Failure of Transplanted Bone Marrow Cells to Adopt a Pancreatic {beta}-Cell Fate.
(
- Contribution to journal › Article
-
Mark
Separately inherited defects in insulin exocytosis and beta-cell glucose metabolism contribute to type 2 diabetes.
(
- Contribution to journal › Article
-
Mark
Tomosyn-1 is involved in a post-docking event required for pancreatic beta-cell exocytosis
(
- Contribution to journal › Article
- 2005
-
Mark
Myosin 5a controls insulin granule recruitment during late-phase secretion.
(
- Contribution to journal › Article
-
Mark
The R6/2 transgenic mouse model of Huntington's disease develops diabetes due to deficient {beta}-cell mass and exocytosis.
(
- Contribution to journal › Article
-
Mark
The ablation of the Ca(v)2.3/E-type voltage-gated Ca2+ channel causes a mild phenotype despite an altered glucose induced glucagon response in isolated islets of Langerhans
(
- Contribution to journal › Article
-
Mark
Redox control of exocytosis - Regulatory role of NADPH, thioredoxin, and glutaredoxin
(
- Contribution to journal › Article
-
Mark
CaV2.3 calcium channels control second-phase insulin release.
(
- Contribution to journal › Article
- 2004
-
Mark
Temperature-Sensitive Random Insulin Granule Diffusion is a Prerequisite for Recruiting Granules for Release.
(
- Contribution to journal › Article
-
Mark
Enhanced cAMP/Protein Kinase A signaling determines improved insulin secretion in a clonal insulin-producing {beta}-cell line (INS-1 832/13).
(
- Contribution to journal › Article
-
Mark
Isoform-specific regulation of mood behavior and pancreatic beta cell and cardiovascular function by L-type Ca2+ channels
(
- Contribution to journal › Article
-
Mark
Large dense-core vesicle exocytosis in pancreatic beta-cells monitored by capacitance measurements
(
- Contribution to journal › Article
- 2003
-
Mark
Insulin granule dynamics in pancreatic beta cells
(
- Contribution to journal › Scientific review
-
Mark
SUR1 Regulates PKA-independent cAMP-induced Granule Priming in Mouse Pancreatic B-cells.
(
- Contribution to journal › Article
-
Mark
Impaired insulin secretion and glucose tolerance in beta cell-selective Ca(V)1.2 Ca(2+) channel null mice.
(
- Contribution to journal › Article
- 2002
-
Mark
Important role of phosphodiesterase 3B for the stimulatory action of cAMP on pancreatic beta -cell exocytosis and release of insulin.
(
- Contribution to journal › Article
-
Mark
Inositol 3,4,5,6-tetrakisphosphate inhibits insulin granule acidification and fusogenic potential.
(
- Contribution to journal › Article
-
Mark
Sulfonylurea-Mediated Stimulation of Insulin Exocytosis via an ATP-Sensitive K(+) Channel--Independent Action.
(
- Contribution to journal › Article
-
Mark
Glucose dependence of insulinotropic actions of pituitary adenylate cyclase-activating polypeptide in insulin-secreting INS-1 cells.
(
- Contribution to journal › Article
-
Mark
A Subset of 50 Secretory Granules in Close Contact With L-Type Ca(2+) Channels Accounts for First-Phase Insulin Secretion in Mouse beta-Cells.
(
- Contribution to journal › Article
-
Mark
Delay between fusion pore opening and peptide release from large dense-core vesicles in neuroendocrine cells.
(
- Contribution to journal › Article
- 2001
-
Mark
Fast exocytosis with few Ca(2+) channels in insulin-secreting mouse pancreatic B cells
(
- Contribution to journal › Article
-
Mark
Differential glucose responsitivity in insulin-producing cell lines derived from the INS-1 line is associated with altered Ca2+dynamics and Ca2+-evoked exocytosis
(
- Contribution to journal › Article
-
Mark
Phosphodiesterase 3B is activated by glucose and insulin in rat islets and involved in Ca2+-stimulated exocytosis
(
- Contribution to journal › Article
-
Mark
Priming of insulin granules for exocytosis by granular Cl(-) uptake and acidification
(
- Contribution to journal › Article
-
Mark
Perchlorate stimulates insulin secretion by shifting the gating of L-type Ca2+ currents in mouse pancreatic B-cells towards negative potentials
(
- Contribution to journal › Article
- 2000
-
Mark
The Cell Physiology of Biphasic Insulin Secretion
(
- Contribution to journal › Article
- 1999
-
Mark
Cell biology. Glutamate primes the pump
(
- Contribution to journal › Article
-
Mark
The stimulatory action of tolbutamide on Ca2+-dependent exocytosis in pancreatic beta cells is mediated by a 65-kDa mdr-like P-glycoprotein
(
- Contribution to journal › Article
-
Mark
CaM kinase II-dependent mobilization of secretory granules underlies acetylcholine-induced stimulation of exocytosis in mouse pancreatic B-cells
(
- Contribution to journal › Article
-
Mark
Activation of Ca(2+)-dependent K(+) channels contributes to rhythmic firing of action potentials in mouse pancreatic beta cells
(
- Contribution to journal › Article
-
Mark
The voltage sensitive Lc-type Ca2+ channel is functionally coupled to the exocytotic machinery
(
- Contribution to journal › Article
- 1997
-
Mark
Components of insulin secretion: lessons to be learnt from capacitance
(
- Contribution to journal › Article
-
Mark
Glucagon-like peptide I and glucose-dependent insulinotropic polypeptide stimulate Ca2+-induced secretion in rat alpha-cells by a protein kinase A-mediated mechanism
(
- Contribution to journal › Article
-
Mark
Multisite regulation of insulin secretion by cAMP-increasing agonists: evidence that glucagon-like peptide 1 and glucagon act via distinct receptors
(
- Contribution to journal › Article
-
Mark
Adrenaline stimulates glucagon secretion in pancreatic A-cells by increasing the Ca2+ current and the number of granules close to the L-type Ca2+ channels
(
- Contribution to journal › Article
-
Mark
Protein kinase A-dependent and -independent stimulation of exocytosis by cAMP in mouse pancreatic B-cells
(
- Contribution to journal › Article
-
Mark
Rapid ATP-dependent priming of secretory granules precedes Ca(2+)-induced exocytosis in mouse pancreatic B-cells
(
- Contribution to journal › Article
- 1996
-
Mark
Dynamics of the cationic, bioelectrical and secretory responses to formycin A in pancreatic islet cells
(
- Contribution to journal › Article
-
Mark
PKC-dependent stimulation of exocytosis by sulfonylureas in pancreatic beta cells
(
- Contribution to journal › Article
-
Mark
Neurotransmitter-induced inhibition of exocytosis in insulin-secreting beta cells by activation of calcineurin
(
- Contribution to journal › Article
-
Mark
Cooling inhibits exocytosis in single mouse pancreatic B-cells by suppression of granule mobilization
(
- Contribution to journal › Article
- 1995
-
Mark
Co-localization of L-type Ca2+ channels and insulin-containing secretory granules and its significance for the initiation of exocytosis in mouse pancreatic B-cells
(
- Contribution to journal › Article
-
Mark
Glucagon-like peptide I increases cytoplasmic calcium in insulin-secreting beta TC3-cells by enhancement of intracellular calcium mobilization
(
- Contribution to journal › Article
- 1994
-
Mark
Ion channels, electrical activity and insulin secretion
(
- Contribution to journal › Article