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- 2021
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Mark
A bacterial protease depletes c-MYC and increases survival in mouse models of bladder and colon cancer
(
- Contribution to journal › Article
-
Mark
A scientific journey from discovery to validation of efficacy in cancer patients : HAMLET and alpha1-oleate
(
- Contribution to journal › Article
-
Mark
Collateral effects of deletion of nlpD on rpoS and rpoS-dependent genes. Reply.
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Bladder cancer therapy using a conformationally fluid tumoricidal peptide complex
(
- Contribution to journal › Article
-
Mark
Active bacterial modification of the host environment through RNA polymerase II inhibition
(
- Contribution to journal › Article
- 2019
-
Mark
Fimbriae reprogram host gene expression - Divergent effects of P and type 1 fimbriae
(
- Contribution to journal › Article
- 2016
-
Mark
A Comparative Analysis of the Mechanism of Toll-Like Receptor-Disruption by TIR-Containing Protein C from Uropathogenic Escherichia coli.
(
- Contribution to journal › Article
-
Mark
Asymtomatic Bacteriuria as a Model to Study the Coevolution of Hosts and Bacteria.
(
- Contribution to journal › Scientific review
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Mark
Uropathogenic Escherichia coli strain CFT073 disrupts NLRP3 inflammasome activation
(
- Contribution to journal › Article
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Mark
Bacterial suppression of RNA polymerase II-dependent host gene expression
(
- Contribution to journal › Scientific review
-
Mark
Deliberate establishment of asymptomatic bacteriuria—a novel strategy to prevent recurrent UTI
(
- Contribution to journal › Scientific review
- 2015
-
Mark
The Molecular Motor F-ATP Synthase Is Targeted by the Tumoricidal Protein HAMLET.
(
- Contribution to journal › Article
- 2013
-
Mark
Electrostatic interactions play an essential role in the binding of oleic acid with a-lactalbumin in the HAMLET-like complex: A study using charge-specific chemical modifications
(
- Contribution to journal › Article
-
Mark
A Unifying Mechanism for Cancer Cell Death through Ion Channel Activation by HAMLET.
(
- Contribution to journal › Article
-
Mark
Bacterial control of host gene expression through RNA polymerase II
(
- Contribution to journal › Article
-
Mark
Urinary tract infections in children: microbial virulence versus host susceptibility.
(
- Contribution to journal › Article
-
Mark
Lipids as Tumoricidal Components of Human Alpha-lactalbumin Made Lethal to Tumor Cells (HAMLET); Unique and Shared Effects on Signaling and Death.
(
- Contribution to journal › Article
-
Mark
Preface
(
- Chapter in Book/Report/Conference proceeding › Book chapter
- 2012
-
Mark
Low Resolution Solution Structure of HAMLET and the Importance of Its Alpha-Domains in Tumoricidal Activity.
(
- Contribution to journal › Article
-
Mark
HAMLET Forms Annular Oligomers When Deposited with Phospholipid Monolayers
(
- Contribution to journal › Article
-
Mark
Polyethyleneimine is a potent mucosal adjuvant for viral glycoprotein antigens
(
- Contribution to journal › Article
-
Mark
Comparison of Asymptomatic Bacteriuria Escherichia coli Isolates from Healthy Individuals versus Those from Hospital Patients Shows that Long-Term Bladder Colonization Selects for Attenuated Virulence Phenotypes
(
- Contribution to journal › Article
-
Mark
Susceptibility to acute pyelonephritis or asymptomatic bacteriuria: Host-pathogen interaction in urinary tract infections.
(
- Contribution to journal › Article
- 2011
-
Mark
Apoptosis-Like Death in Bacteria Induced by HAMLET, a Human Milk Lipid-Protein Complex
(
- Contribution to journal › Article
-
Mark
HAMLET Binding to α-Actinin Facilitates Tumor Cell Detachment.
(
- Contribution to journal › Article
-
Mark
MiR-129-5p is required for histone deacetylase inhibitor-induced cell death in thyroid cancer cells
(
- Contribution to journal › Article
-
Mark
Genetics of innate immunity and UTI susceptibility.
(
- Contribution to journal › Article
-
Mark
Genetic control of the variable innate immune response to asymptomatic bacteriuria.
(
- Contribution to journal › Article
- 2010
-
Mark
HAMLET interacts with lipid membranes and perturbs their structure and integrity.
(
- Contribution to journal › Article
-
Mark
Host Imprints on Bacterial Genomes-Rapid, Divergent Evolution in Individual Patients
(
- Contribution to journal › Article
-
Mark
Inhibition of TIR domain signaling by TcpC: MyD88-dependent and independent effects on Escherichia coli virulence.
(
- Contribution to journal › Article
-
Mark
Pathogen specific, IRF3-dependent signaling and innate resistance to human kidney infection.
(
- Contribution to journal › Article
-
Mark
Toll-Like Receptor 4 Promoter Polymorphisms: Common TLR4 Variants May Protect against Severe Urinary Tract Infection.
(
- Contribution to journal › Article
- 2009
-
Mark
Characterizing Escherichia coli asymptomatic bacteriuria (ABU) - what drives their successful silent colonization?
2009) 61st Conference of the Deutschen-Gesellschaft-fur-Hygiene-und-Microbiologie In International Journal of Medical Microbiology 299. p.54-54(
- Contribution to journal › Published meeting abstract
-
Mark
alpha-Lactalbumin, Engineered to be Non-native and Inactive, Kills Tumor Cells when in Complex with Oleic Acid: A new biological function resulting from partial unfolding.
(
- Contribution to journal › Article
-
Mark
Therapeutic Effect of Blocking CXCR2 on Neutrophil Recruitment and Dextran Sodium Sulfate-Induced Colitis
(
- Contribution to journal › Article
-
Mark
Virulence properties of asymptomatic bacteriuria Escherichia coli
(
- Contribution to journal › Article
-
Mark
Changes in proteasome structure and function caused by HAMLET in tumor cells.
(
- Contribution to journal › Article
- 2008
-
Mark
Asymptomatic Bacteriuria: An adaptive challenge for Escherichia coli within the urinary tract
2008) 60th Annual Meeting of the Deutschen-Gesellschaft-fur-Hygiene-und-Mikrobiologie In International Journal of Medical Microbiology 298. p.76-76(
- Contribution to journal › Published meeting abstract
-
Mark
Molecular basis of commensalism in the urinary tract: low virulence or virulence attenuation?
(
- Contribution to journal › Article
-
Mark
Apoptosis and tumor cell death in response to HAMLET (human alpha-lactalbumin made lethal to tumor cells).
(
- Contribution to journal › Scientific review
-
Mark
TLR- and CXCR1-dependent innate immunity: insights into the genetics of urinary tract infections.
(
- Contribution to journal › Scientific review
-
Mark
Subversion of Toll-like receptor signaling by a unique family of bacterial Toll/interleukin-1 receptor domain-containing proteins
(
- Contribution to journal › Article
- 2007
-
Mark
A genetic basis of susceptibility to acute pyelonephritis.
(
- Contribution to journal › Article
- 2006
-
Mark
Glycolipid receptor depletion as an approach to specific antimicrobial therapy.
(
- Contribution to journal › Scientific review
-
Mark
HAMLET triggers apoptosis but tumor cell death is independent of caspases, Bcl-2 and p53.
(
- Contribution to journal › Article
-
Mark
Uropathogenic Escherichia coli as a model of host-parasite interaction.
(
- Contribution to journal › Scientific review
-
Mark
Molecular characterization of the Escherichia coli asymptomatic bacteriuria strain 83972: The taming of a pathogen
(
- Contribution to journal › Article
- 2005
-
Mark
Expression of nitric oxide synthase isoforms in the mouse kidney: cellular localization and influence by lipopolysaccharide and Toll-like receptor 4.
(
- Contribution to journal › Article
-
Mark
Stability of HAMLET--A kinetically trapped {alpha}-lactalbumin oleic acid complex.
(
- Contribution to journal › Article
-
Mark
Escherichia coli, fimbriae, bacterial persistence and host response induction in the human urinary tract.
(
- Contribution to journal › Scientific review
-
Mark
HAMLET; a novel tool to identify apoptotic pathways in tumor cells.
2005) p.223-245(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Urinary tract infections and the mucosal Immune system
2005) p.1601-1601(
- Chapter in Book/Report/Conference proceeding › Book chapter
- 2004
-
Mark
Treatment of skin papillomas with topical alpha-lactalbumin-oleic acid
(
- Contribution to journal › Article
-
Mark
Conformational analysis of HAMLET, the folding variant of human alpha-lactalbumin associated with apoptosis
(
- Contribution to journal › Article
-
Mark
Human alpha-lactalbumin made lethal to tumor cells (HAMLET) kills human glioblastoma cells in brain xenografts by an apoptosis-like mechanism and prolongs survival.
(
- Contribution to journal › Article
-
Mark
Toll-like receptor 4 expression and cytokine responses in the human urinary tract mucosa.
(
- Contribution to journal › Article
-
Mark
Urinary tract infections as a model for innate mucosal immunity
2004) p.157-157(
- Chapter in Book/Report/Conference proceeding › Book chapter
- 2003
-
Mark
Glycolipid depletion in antimicrobial therapy
(
- Contribution to journal › Article
-
Mark
HAMLET interacts with histones and chromatin in tumor cell nuclei.
(
- Contribution to journal › Article
-
Mark
Lipids as cofactors in protein folding: Stereo-specific lipid-protein interactions are required to form HAMLET (human alpha-lactalbumin made lethal to tumor cells).
(
- Contribution to journal › Article
-
Mark
HAMLET kills tumor cells by an apoptosis-like mechanism--cellular, molecular, and therapeutic aspects.
(
- Contribution to journal › Scientific review
-
Mark
The host response to urinary tract infection.
(
- Contribution to journal › Article
-
Mark
alpha-Lactalbumin unfolding is not sufficient to cause apoptosis, but is required for the conversion to HAMLET (human alpha-lactalbumin made lethal to tumor cells).
(
- Contribution to journal › Article
- 2002
-
Mark
Hamlet - A complex from human milk that induces apoptosis in tumor cells but spares healthy cells
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Adhesion, signal transduction and mucosal inflammation
2002) p.223-247(
- Chapter in Book/Report/Conference proceeding › Book chapter
- 2001
-
Mark
Escherichia coli P fimbriae utilize the Toll-like receptor 4 pathway for cell activation
(
- Contribution to journal › Article
-
Mark
Type 1 fimbriae deliver an LPS- and TLR4-dependent activation signal to CD14-negative cells
(
- Contribution to journal › Article
-
Mark
Use of green fluorescent protein in visualisation of pneumococcal invasion of broncho-epithelial cells in vivo
(
- Contribution to journal › Article
-
Mark
The 'innate' host response protects and damages the infected urinary tract
(
- Contribution to journal › Article
-
Mark
A folding variant of human alpha-lactalbumin induces mitochondrial permeability transition in isolated mitochondria
(
- Contribution to journal › Article
-
Mark
P-fimbriae trigger mucosal responses to Escherichia coli in the human urinary tract
(
- Contribution to journal › Article
- 2000
-
Mark
Innate defences and resistance to gram negative mucosal infection
(
- Contribution to journal › Article
-
Mark
Interleukin 8 receptor deficiency confers susceptibility to acute experimental pyelonephritis and may have a human counterpart
(
- Contribution to journal › Article
-
Mark
P fimbriae enhance the early establishment of Escherichia coli in the human urinary tract
(
- Contribution to journal › Article
-
Mark
A folding variant of alpha-lactalbumin with bactericidal activity against Streptococcus pneumoniae
(
- Contribution to journal › Article
- 1999
-
Mark
Cytokine responses during mucosal infections: role in disease pathogenesis and host defence
(
- Contribution to journal › Article
- 1998
-
Mark
Role of fimbriae-mediated adherence for neutrophil migration across Escherichia coli-infected epithelial cell layers
(
- Contribution to journal › Article
-
Mark
Apoptosis of renal cortical cells in the hemolytic-uremic syndrome: : In vivo and in vitro studies
(
- Contribution to journal › Article
- 1997
-
Mark
Bacterial virulence in urinary tract infection
(
- Contribution to journal › Article
-
Mark
Role of epithelial interleukin-8 (IL-8) and neutrophil IL-8 receptor A in Escherichia coli-induced transuroepithelial neutrophil migration
(
- Contribution to journal › Article
- 1996
-
Mark
Type 1 fimbrial expression enhances Escherichia coli virulence for the urinary tract
1996) In Proceedings of the National Academy of Sciences of the United States of America 93(18). p.9827-9832(
- Contribution to journal › Article
- 1995
-
Mark
Cytokines induce an epithelial cell cytokine response
(
- Contribution to journal › Article
-
Mark
Epithelial cytokine responses and mucosal cytokine networks
(
- Contribution to journal › Scientific review
-
Mark
Binding of Haemophilus influenzae to purified mucins from the human respiratory tract
(
- Contribution to journal › Article
- 1994
-
Mark
Bacterial Adherence and Mucosal Cytokine Production
(
- Contribution to journal › Article
- 1993
-
Mark
Interleukin-8 and the neutrophil response to mucosal gram-negative infection
(
- Contribution to journal › Article