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- 2024
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Mark
Nucleotide binding to the ATP-cone in anaerobic ribonucleotide reductases allosterically regulates activity by modulating substrate binding
(
- Contribution to journal › Article
- 2022
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Mark
A nucleotide-sensing oligomerization mechanism that controls NrdR-dependent transcription of ribonucleotide reductases
(
- Contribution to journal › Article
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Mark
Dusquetide modulates innate immune response through binding to p62
(
- Contribution to journal › Article
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Mark
The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis
(
- Contribution to journal › Article
- 2021
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Mark
Solution Structure of the dATP-Inactivated Class I Ribonucleotide Reductase From Leeuwenhoekiella blandensis by SAXS and Cryo-Electron Microscopy
(
- Contribution to journal › Article
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Mark
DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously
(
- Contribution to journal › Article
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Mark
Entropy–Entropy Compensation between the Protein, Ligand, and Solvent Degrees of Freedom Fine-Tunes Affinity in Ligand Binding to Galectin-3C
(
- Contribution to journal › Article
- 2020
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Mark
Interactive model building in neutron macromolecular crystallography
(
- Chapter in Book/Report/Conference proceeding › Book chapter
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Mark
Exposing the distinctive modular behavior of β-strands and α-helices in folded proteins
2020) In Proceedings of the National Academy of Sciences of the United States of America 117(46). p.28775-28783(
- Contribution to journal › Article
- 2019
-
Mark
Substituted polyfluoroaryl interactions with an arginine side chain in galectin-3 are governed by steric-, desolvation and electronic conjugation effects
(
- Contribution to journal › Article
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Mark
Interplay between Conformational Entropy and Solvation Entropy in Protein-Ligand Binding
(
- Contribution to journal › Article
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Mark
Are crystallographic : B-factors suitable for calculating protein conformational entropy?
(
- Contribution to journal › Article
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Mark
3-Substituted 1-Naphthamidomethyl-C-galactosyls Interact with Two Unique Sub-Sites for High-Affinity and High-Selectivity Inhibition of Galectin-3
(
- Contribution to journal › Article
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Mark
Hunting down hydrogen : Applying neutron macromolecular crystallography to galectins
(
- Contribution to journal › Article
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Mark
A surface-exposed GH26 -mannanase from Bacteroides ovatus : Structure, role, and phylogenetic analysis of BoMan26B
(
- Contribution to journal › Article
-
Mark
Insight into the dimer dissociation process of the Chromobacterium violaceum (S)-selective amine transaminase
(
- Contribution to journal › Article
-
Mark
Structure-based design and in vivo anti-arthritic activity evaluation of a potent dipeptidyl cyclopropyl nitrile inhibitor of cathepsin C
(
- Contribution to journal › Article
-
Mark
Discovery of three novel sesquiterpene synthases from Streptomyces chartreusis NRRL 3882 and crystal structure of an α-eudesmol synthase
(
- Contribution to journal › Article
- 2018
-
Mark
The Cost of Long Catalytic Loops in Folding and Stability of the ALS-Associated Protein SOD1
(
- Contribution to journal › Article
-
Mark
Designing interactions by control of protein-ligand complex conformation : Tuning arginine-arene interaction geometry for enhanced electrostatic protein-ligand interactions
(
- Contribution to journal › Article
-
Mark
Novel ATP-cone-driven allosteric regulation of ribonucleotide reductase via the radical-generating subunit
(
- Contribution to journal › Article
-
Mark
Synthesis of branched and linear 1,4-linked galactan oligosaccharides
(
- Contribution to journal › Article
- 2017
-
Mark
Crystal structure of β-glucosidase 1A from Thermotoga neapolitana and comparison of active site mutants for hydrolysis of flavonoid glucosides
(
- Contribution to journal › Article
-
Mark
Galactomannan catabolism conferred by a polysaccharide utilisation locus of Bacteroides ovatus : enzyme synergy and crystal structure of a β-mannanase
(
- Contribution to journal › Article
-
Mark
Three-dimensional structures and functional studies of two GH43 arabinofuranosidases from Weissella sp. strain 142 and Lactobacillus brevis
(
- Contribution to journal › Article
- 2016
-
Mark
A de Novo Designed Coiled-Coil Peptide with a Reversible pH-Induced Oligomerization Switch
(
- Contribution to journal › Article
-
Mark
Tricking a Protein To Swap Strands
(
- Contribution to journal › Article
- 2015
-
Mark
The Crystal Structure of Thermotoga maritima Class III Ribonucleotide Reductase Lacks a Radical Cysteine Pre-Positioned in the Active Site
(
- Contribution to journal › Article
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Mark
Crystallization, neutron data collection, initial structure refinement and analysis of a xyloglucan heptamer bound to an engineered carbohydrate-binding module from xylanase.
(
- Contribution to journal › Article
-
Mark
Neutron Crystallographic Studies Reveal Hydrogen Bond and Water-Mediated Interactions between a Carbohydrate-Binding Module and Its Bound Carbohydrate Ligand.
(
- Contribution to journal › Article
- 2012
-
Mark
Structural basis for carbohydrate binding specificity - a comparative assessment of two engineered carbohydrate binding modules.
(
- Contribution to journal › Article
-
Mark
Crystal structures of the Chromobacterium violaceumω-transaminase reveal major structural rearrangements upon binding of coenzyme PLP.
(
- Contribution to journal › Article
-
Mark
The Carbohydrate-Binding Site in Galectin-3 Is Preorganized To Recognize a Sugarlike Framework of Oxygens: Ultra-High-Resolution Structures and Water Dynamics
(
- Contribution to journal › Article
- 2010
-
Mark
High-resolution crystal structures of the flavoprotein NrdI in oxidized and reduced states - an unusual flavodoxin: Structural biology.
(
- Contribution to journal › Article
-
Mark
Structural Basis for Adenosylcobalamin Activation in AdoCbl-Dependent Ribonucleotide Reductases
(
- Contribution to journal › Article
- 2009
-
Mark
Phosphorylation of hormone-sensitive lipase by protein kinase A in vitro promotes an increase in its hydrophobic surface area.
(
- Contribution to journal › Article
- 2001
-
Mark
Structure and function of the radical enzyme ribonucleotide reductase
(
- Contribution to journal › Scientific review
- 1999
-
Mark
A glycyl radical site in the crystal structure of a class III ribonucleotide reductase
(
- Contribution to journal › Article
- 1998
-
Mark
Crystal structures of two self-hydroxylating ribonucleotide reductase protein R2 mutants : Structural basis for the oxygen-insertion step of hydroxylation reactions catalyzed by diiron proteins
(
- Contribution to journal › Article
-
Mark
Glycyl-tRNA synthetase from Thermus thermophilus : Wide structural divergence with other prokaryotic glycyl-tRNA synthetases and functional inter-relation with prokaryotic and eukaryotic glycylation systems
(
- Contribution to journal › Article
- 1997
-
Mark
Kinetics of transient radicals in Escherichia coli ribonucleotide reductase : Formation of a new tyrosyl radical in mutant protein R2
(
- Contribution to journal › Article
-
Mark
Ribonucleotide reductase - Structural studies of a radical enzyme
(
- Contribution to journal › Scientific review
- 1996
-
Mark
Crystal structure of reduced protein R2 of ribonucleotide reductase : The structural basis for oxygen activation at a dinuclear iron site
(
- Contribution to journal › Article
- 1995
-
Mark
Crystal structure of glycyl-tRNA synthetase from Thermus thermophilus
(
- Contribution to journal › Article
- 1994
-
Mark
The structure of an immunodominant loop on foot and mouth disease virus, serotype O1, determined under reducing conditions
(
- Contribution to journal › Scientific review
-
Mark
Crystallisation of the Glycyl-tRNA synthetase from thermus thermophilus and initial crystallographic data
(
- Contribution to journal › Article
- 1993
-
Mark
Structure of a major immunogenic site on foot-and-mouth disease virus
(
- Contribution to journal › Article