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- 2022
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Mark
Genome-wide meta-analysis and omics integration identifies novel genes associated with diabetic kidney disease
(
- Contribution to journal › Article
-
Mark
Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes
(
- Contribution to journal › Article
- 2021
-
Mark
Genome-wide association analyses highlight etiological differences underlying newly defined subtypes of diabetes
(
- Contribution to journal › Article
-
Mark
Genome-Wide Association Study of Peripheral Artery Disease
(
- Contribution to journal › Article
-
Mark
Genome-Wide Association Analysis of Pancreatic Beta-Cell Glucose Sensitivity
(
- Contribution to journal › Article
-
Mark
Profiles of Glucose Metabolism in Different Prediabetes Phenotypes, Classified by Fasting Glycemia, 2-Hour OGTT, Glycated Hemoglobin, and 1-Hour OGTT : An IMI DIRECT Study
(
- Contribution to journal › Article
-
Mark
Processes Underlying Glycemic Deterioration in Type 2 Diabetes : An IMI DIRECT Study
(
- Contribution to journal › Article
-
Mark
Inferring causal pathways between metabolic processes and liver fat accumulation: an IMI DIRECT study
2021) In medRxiv(
- Working paper/Preprint › Preprint in preprint archive
- 2020
-
Mark
Precision Medicine in Diabetes : A Consensus Report From the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
(
- Contribution to journal › Scientific review
-
Mark
Precision medicine in diabetes : a Consensus Report from the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
(
- Contribution to journal › Article
-
Mark
The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes : an IMI DIRECT study
(
- Contribution to journal › Article
-
Mark
Genome-wide association analysis of type 2 diabetes in the EPIC-InterAct study
(
- Contribution to journal › Article
-
Mark
Dietary metabolite profiling brings new insight into the relationship between nutrition and metabolic risk : An IMI DIRECT study
(
- Contribution to journal › Article
-
Mark
Post-load glucose subgroups and associated metabolic traits in individuals with type 2 diabetes : An IMI-DIRECT study
(
- Contribution to journal › Article
-
Mark
Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D
(
- Contribution to journal › Article
- 2019
-
Mark
The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia : design, results and future prospects
(
- Contribution to journal › Article
-
Mark
Variation in the plasma membrane monoamine transporter (PMAT) (encoded by SLC29A4) and organic cation transporter 1 (OCT1) (encoded by SLC22A1) and gastrointestinal intolerance to metformin in type 2 diabetes : An IMI direct study
(
- Contribution to journal › Article
-
Mark
Fostering improved human islet research : a European perspective
(
- Contribution to journal › Letter
-
Mark
Integrative analysis of prognostic biomarkers derived from multiomics panels helps discrimination of chronic kidney disease trajectories in people with type 2 diabetes
(
- Contribution to journal › Article
-
Mark
DOLORisk : Study protocol for a multi-centre observational study to understand the risk factors and determinants of neuropathic pain [version 2; referees: 2 approved]
(
- Contribution to journal › Article
-
Mark
A novel rare CUBN variant and three additional genes identified in Europeans with and without diabetes : results from an exome-wide association study of albuminuria
(
- Contribution to journal › Article
-
Mark
Loss of ZnT8 function protects against diabetes by enhanced insulin secretion
(
- Contribution to journal › Article
- 2018
-
Mark
A global overview of precision medicine in type 2 diabetes
(
- Contribution to journal › Scientific review
-
Mark
A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes
(
- Contribution to journal › Article
-
Mark
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes article
(
- Contribution to journal › Article
-
Mark
Validation of Plasma Biomarker Candidates for the Prediction of eGFR Decline in Patients With Type 2 Diabetes
(
- Contribution to journal › Article
-
Mark
A variant within the FTO confers susceptibility to diabetic nephropathy in Japanese patients with type 2 diabetes
(
- Contribution to journal › Article
-
Mark
Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference
(
- Contribution to journal › Article
-
Mark
A genome-wide association study suggests new evidence for an association of the NADPH Oxidase 4 (NOX4) gene with severe diabetic retinopathy in type 2 diabetes
(
- Contribution to journal › Article
- 2017
-
Mark
The genetic landscape of renal complications in type 1 diabetes
(
- Contribution to journal › Article
-
Mark
Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance
(
- Contribution to journal › Article
-
Mark
Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease
(
- Contribution to journal › Article
-
Mark
New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals
(
- Contribution to journal › Article
- 2016
-
Mark
Exposing the exposures responsible for type 2 diabetes and obesity
(
- Contribution to journal › Scientific review
-
Mark
The genetic architecture of type 2 diabetes
(
- Contribution to journal › Article
-
Mark
Association between low-density lipoprotein cholesterol-lowering genetic variants and risk of type 2 diabetes : A meta-analysis
(
- Contribution to journal › Article
-
Mark
Analysis with the exome array identifies multiple new independent variants in lipid loci
(
- Contribution to journal › Article
-
Mark
A reference panel of 64,976 haplotypes for genotype imputation
(
- Contribution to journal › Article
-
Mark
Coding variation in ANGPTL4, LPL, and SVEP1 and the risk of coronary disease
(
- Contribution to journal › Article
-
Mark
A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease
(
- Contribution to journal › Article
-
Mark
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension
(
- Contribution to journal › Article
-
Mark
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.
(
- Contribution to journal › Article
-
Mark
A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape
(
- Contribution to journal › Article
-
Mark
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals
(
- Contribution to journal › Article
- 2015
-
Mark
The genetics of diabetic complications.
(
- Contribution to journal › Scientific review
-
Mark
Harmonising and linking biomedical and clinical data across disparate data archives to enable integrative cross-biobank research.
2015) In European Journal of Human Genetics(
- Contribution to journal › Article
-
Mark
Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation.
(
- Contribution to journal › Article
-
Mark
The impact of low-frequency and rare variants on lipid levels.
(
- Contribution to journal › Article
-
Mark
Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus.
(
- Contribution to journal › Article
-
Mark
Age- and Sex-Specific Causal Effects of Adiposity on Cardiovascular Risk Factors.
(
- Contribution to journal › Article
-
Mark
Rare coding variants and X-linked loci associated with age at menarche
(
- Contribution to journal › Article
-
Mark
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.
(
- Contribution to journal › Article
-
Mark
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.
(
- Contribution to journal › Article
-
Mark
New genetic loci link adipose and insulin biology to body fat distribution.
(
- Contribution to journal › Article
-
Mark
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
(
- Contribution to journal › Article
-
Mark
Genetic studies of body mass index yield new insights for obesity biology.
(
- Contribution to journal › Article
- 2014
-
Mark
Heritability of variation in glycaemic response to metformin: a genome-wide complex trait analysis.
(
- Contribution to journal › Article
-
Mark
Expression of Phosphofructokinase in Skeletal Muscle Is Influenced by Genetic Variation and Associated With Insulin Sensitivity
(
- Contribution to journal › Article
-
Mark
Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes.
(
- Contribution to journal › Article
-
Mark
Gene-Lifestyle Interaction and Type 2 Diabetes: The EPIC InterAct Case-Cohort Study.
(
- Contribution to journal › Article
-
Mark
Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independently of obesity.
(
- Contribution to journal › Article
-
Mark
Distribution and Medical Impact of Loss-of-Function Variants in the Finnish Founder Population.
(
- Contribution to journal › Article
-
Mark
A Central Role for GRB10 in Regulation of Islet Function in Man.
(
- Contribution to journal › Article
-
Mark
Loss-of-function mutations in SLC30A8 protect against type 2 diabetes.
(
- Contribution to journal › Article
-
Mark
Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study.
(
- Contribution to journal › Article
-
Mark
Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins.
(
- Contribution to journal › Article
-
Mark
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
(
- Contribution to journal › Article
-
Mark
Defining the role of common variation in the genomic and biological architecture of adult human height.
(
- Contribution to journal › Article
- 2013
-
Mark
Insights Into the Molecular Mechanism for Type 2 Diabetes Susceptibility at the KCNQ1 Locus From Temporal Changes in Imprinting Status in Human Islets
(
- Contribution to journal › Article
-
Mark
Higher Magnesium Intake Is Associated with Lower Fasting Glucose and Insulin, with No Evidence of Interaction with Select Genetic Loci, in a Meta-Analysis of 15 CHARGE Consortium Studies
(
- Contribution to journal › Article
-
Mark
Meta-Analysis Investigating Associations Between Healthy Diet and Fasting Glucose and Insulin Levels and Modification by Loci Associated With Glucose Homeostasis in Data From 15 Cohorts
(
- Contribution to journal › Scientific review
-
Mark
The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis
(
- Contribution to journal › Article
-
Mark
Large-scale association analysis identifies new risk loci for coronary artery disease
(
- Contribution to journal › Article
-
Mark
Common variants associated with plasma triglycerides and risk for coronary artery disease
(
- Contribution to journal › Article
-
Mark
Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits
(
- Contribution to journal › Article
-
Mark
Discovery and refinement of loci associated with lipid levels
(
- Contribution to journal › Article
-
Mark
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
(
- Contribution to journal › Article
- 2012
-
Mark
Reduced Insulin Exocytosis in Human Pancreatic β-cells With Gene Variants Linked to Type 2 Diabetes.
(
- Contribution to journal › Article
-
Mark
Stratifying Type 2 Diabetes Cases by BMI Identifies Genetic Risk Variants in LAMA1 and Enrichment for Risk Variants in Lean Compared to Obese Cases
(
- Contribution to journal › Article
-
Mark
A Genome-Wide Association Meta-Analysis of Circulating Sex Hormone-Binding Globulin Reveals Multiple Loci Implicated in Sex Steroid Hormone Regulation
(
- Contribution to journal › Article
-
Mark
FTO genotype is associated with phenotypic variability of body mass index
(
- Contribution to journal › Article
-
Mark
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
(
- Contribution to journal › Article
-
Mark
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
(
- Contribution to journal › Article
-
Mark
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
(
- Contribution to journal › Article
- 2011
-
Mark
Total Zinc Intake May Modify the Glucose-Raising Effect of a Zinc Transporter (SLC30A8) Variant A 14-Cohort Meta-analysis
(
- Contribution to journal › Article
-
Mark
Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes
(
- Contribution to journal › Article
- 2010
-
Mark
Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes
(
- Contribution to journal › Article
-
Mark
Detailed Physiologic Characterization Reveals Diverse Mechanisms for Novel Genetic Loci Regulating Glucose and Insulin Metabolism in Humans
(
- Chapter in Book/Report/Conference proceeding › Paper in conference proceeding
-
Mark
Genetic loci influencing kidney function and chronic kidney disease
(
- Contribution to journal › Article
-
Mark
Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution
(
- Contribution to journal › Article
-
Mark
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
(
- Contribution to journal › Article
-
Mark
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
(
- Contribution to journal › Article
-
Mark
Biological, clinical and population relevance of 95 loci for blood lipids
(
- Contribution to journal › Article
-
Mark
Hundreds of variants clustered in genomic loci and biological pathways affect human height
(
- Contribution to journal › Article
-
Mark
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
(
- Contribution to journal › Article
-
Mark
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
(
- Contribution to journal › Article
-
Mark
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
(
- Contribution to journal › Article
- 2009
-
Mark
Novel Genetic Loci Implicated in Fasting Glucose Homeostasis and Their Impact on Related Metabolic Traits
2009) 18th Annual Meeting of the International-Genetic-Epidemiology-Society In Genetic Epidemiology 33(8). p.124-124(
- Contribution to journal › Published meeting abstract
-
Mark
Underlying Genetic Models of Inheritance in Established Type 2 Diabetes Associations
(
- Contribution to journal › Scientific review
-
Mark
Variants in MTNR1B influence fasting glucose levels
(
- Contribution to journal › Article
-
Mark
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
(
- Contribution to journal › Article
-
Mark
Genome-wide association study identifies eight loci associated with blood pressure
(
- Contribution to journal › Article
- 2008
-
Mark
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
(
- Contribution to journal › Article
- 2007
-
Mark
Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes
(
- Contribution to journal › Article
-
Mark
A common variant of HMGA2 is associated with adult and childhood height in the general population
(
- Contribution to journal › Article
- 2003
-
Mark
A meta-analysis of four European genome screens (GIFT Consortium) shows evidence for a novel region on chromosome 17p11.2-q22 linked to type 2 diabetes.
(
- Contribution to journal › Article