Tumor microenvironment
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- 2013
-
Mark
Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.
Kucharzewska, Paulina LU ; Christianson, Helena LU ; Welch, Johanna LU ; Svensson, Katrin LU ; Fredlund, Erik LU ; Ringnér, Markus LU
; Mörgelin, Matthias
LU
; Bourseau-Guilmain, Erika
LU
; Bengzon, Johan
LU
and Belting, Mattias
LU
(2013)
In Proceedings of the National Academy of Sciences
110(18).
p.7312-7317
- Contribution to journal › Article
-
Mark
Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity.
- Contribution to journal › Article
-
Mark
Exosome uptake depends on ERK1/2-heat shock protein 27 signalling and lipid raft-mediated endocytosis negatively regulated by caveolin-1.
- Contribution to journal › Article
- 2011
-
Mark
Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2-mediated heparin-binding EGF signaling in endothelial cells.
Svensson, Katrin LU ; Kucharzewska, Paulina LU ; Christianson, Helena LU ; Sköld, Stefan LU ; Löfstedt, Tobias ; Johansson, Maria C LU
; Mörgelin, Matthias
LU
; Bengzon, Johan
LU
; Ruf, Wolfram
and Belting, Mattias
LU
(2011)
In Proceedings of the National Academy of Sciences
108(32).
p.13147-13152
- Contribution to journal › Article
- 2010
-
Mark
Evidence for tissue factor phosphorylation and its correlation with protease activated receptor expression and the prognosis of primary breast cancer.
Rydén, Lisa LU
; Grabau, Dorthe
LU
; Schaffner, Florence
; Jönsson, Per-Ebbe
LU
; Ruf, Wolfram
and Belting, Mattias
LU
(2010)
In International Journal of Cancer
126(10).
p.2330-2340
- Contribution to journal › Article
-
Mark
Magnetic nanoparticle-based isolation of endocytic vesicles reveals a role of the heat shock protein GRP75 in macromolecular delivery.
Wittrup, Anders LU ; Zhang, Sihe LU ; Svensson, Katrin LU ; Kucharzewska, Paulina LU ; Johansson, Maria C LU
; Mörgelin, Matthias
LU
and Belting, Mattias
LU
(2010)
In Proceedings of the National Academy of Sciences
107(30).
p.13342-13347
- Contribution to journal › Article
- 2009
-
Mark
ScFv antibody-induced translocation of cell-surface heparan sulfate proteoglycan to endocytic vesicles: Evidence for heparan sulfate epitope specificity and role of both syndecan and glypican.
Wittrup, Anders LU ; Zhang, Sihe LU ; Ten Dam, Gerdy B ; van Kuppevelt, Toin H ; Bengtson, Per LU ; Johansson, Maria C LU
; Welch, Johanna
LU
; Mörgelin, Matthias
LU
and Belting, Mattias
LU
(2009)
In Journal of Biological Chemistry
284(47).
p.32959-32967
- Contribution to journal › Article
- 2008
-
Mark
Hypoxia-mediated induction of the polyamine system provides opportunities for tumor growth inhibition by combined targeting of vascular endothelial growth factor and ornithine decarboxylase.
- Contribution to journal › Article
-
Mark
Nanotubes, exosomes, and nucleic acid-binding peptides provide novel mechanisms of intercellular communication in eukaryotic cells: implications in health and disease.
- Contribution to journal › Article
- 2007
-
Mark
Identification of proteins released by mammalian cells that mediate DNA internalization through proteoglycan-dependent macropinocytosis
- Contribution to journal › Article