Division of Molecular Medicine and Gene Therapy
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- 2014
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Mark
Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism.
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- Contribution to journal › Article
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Mark
Optogenetic control of insulin secretion in intact pancreatic islets with β-cell-specific expression of Channelrhodopsin-2.
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- Contribution to journal › Article
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Mark
Gene therapy cures the anemia and lethal bone marrow failure in mouse model for RPS19-deficient Diamond-Blackfan anemia.
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- Contribution to journal › Article
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Mark
The epigenetic landscape of aneuploidy: constitutional mosaicism leading the way?
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- Contribution to journal › Article
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Mark
Musculoskeletal Pain in Patients With Chronic Myeloid Leukemia After Discontinuation of Imatinib: A Tyrosine Kinase Inhibitor Withdrawal Syndrome?
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- Contribution to journal › Letter
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Mark
Hypoxic induction of vascular endothelial growth factor regulates erythropoiesis but not hematopoietic stem cell function in the fetal liver.
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- Contribution to journal › Article
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Mark
Brain pericytes acquire a microglial phenotype after stroke.
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- Contribution to journal › Article
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Mark
Modeling chronic myeloid leukemia in immunodeficient mice reveals expansion of aberrant mast cells and accumulation of pre-B cells.
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- Contribution to journal › Article
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Mark
Sortilin expression is essential for pro-nerve growth factor-induced apoptosis of rat vascular smooth muscle cells.
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- Contribution to journal › Article
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Mark
Development of Novel Models for Studying Osteoclasts
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- Thesis › Doctoral thesis (compilation)
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Mark
Gene expression profiling to define the cell intrinsic role of the SKI proto-oncogene in hematopoiesis and myeloid neoplasms.
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- Contribution to journal › Article
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Mark
HIF-1α can act as a tumor suppressor gene in murine Acute Myeloid Leukemia.
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- Contribution to journal › Article
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Mark
Myelodysplastic Syndromes Are Propagated by Rare and Distinct Human Cancer Stem Cells In Vivo.
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- Contribution to journal › Article
- 2013
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Mark
Adenovirus Serotype 5 Vectors with Tat-PTD Modified Hexon and Serotype 35 Fiber Show Greatly Enhanced Transduction Capacity of Primary Cell Cultures
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- Contribution to journal › Article
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Mark
Defining Regulators of Human Hematopoietic Stem Cells
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- Thesis › Doctoral thesis (compilation)
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Mark
Functional and genetic characterization of the non-lysosomal glucosylceramidase 2 as a modifier for Gaucher disease
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- Contribution to journal › Article
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Mark
Impact of malignant stem cell burden on therapy outcome in newly diagnosed chronic myeloid leukemia patients
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- Contribution to journal › Article
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Mark
40K glycoPEGylated, recombinant FVIIa: 3-month, double-blind, randomized trial of safety, pharmacokinetics, and preliminary efficacy in hemophilia patients with inhibitors.
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- Contribution to journal › Article
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Mark
Lymphomyeloid Contribution of an Immune-Restricted Progenitor Emerging Prior to Definitive Hematopoietic Stem Cells.
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- Contribution to journal › Article
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Mark
Identification of the chemokine CCL28 as a growth and survival factor for human hematopoietic stem- and progenitor cells.
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- Contribution to journal › Article
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Mark
Tyrosine kinase inhibitor usage, treatment outcome, and prognostic scores in CML: report from the population-based Swedish CML registry
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- Contribution to journal › Article
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Mark
Response to letter to the editor 'Serum cystatin-C levels correlate with endothelial dysfunction in patients with the metabolic syndrome'
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- Contribution to journal › Letter
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Mark
B cell lymphoma and myeloma in murine Gaucher's disease
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- Contribution to journal › Article
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Mark
Lentiviral gene transfer of TCIRG1 into peripheral blood CD34(+) cells restores osteoclast function in infantile malignant osteopetrosis.
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- Contribution to journal › Article
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Mark
Interfering with histone demethylases in HSCs.
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- Contribution to journal › Debate/Note/Editorial
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Mark
FACS binding assay for analysing GDNF interactions.
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- Contribution to journal › Article
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Mark
Fetal hepatic progenitors support long-term expansion of hematopoietic stem cells
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- Contribution to journal › Article
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Mark
Sox4 Is a Key Oncogenic Target in C/EBP alpha Mutant Acute Myeloid Leukemia
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- Contribution to journal › Article
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Mark
Osteoclasts are not crucial for hematopoietic stem cell maintenance in adult mice
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- Contribution to journal › Article
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Mark
Expression of Integrin A2 Receptor in Human Cord Blood Cd34+Cd38-Cd90+ Stem Cells Engrafting Long-Term in Nod/Scid-Il2rγ(C) Null Mice.
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- Contribution to journal › Article
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Mark
The Tetraspanin CD9 Affords High-Purity Capture of All Murine Hematopoietic Stem Cells
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- Contribution to journal › Article
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Mark
A Robust Screening Assay For Diamond Blackfan Anemia Candidate Drugs
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- Contribution to journal › Published meeting abstract
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Mark
Increased glucocerebrosidase (GBA) 2 activity in GBA1 deficient mice brains and in Gaucher leucocytes
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- Contribution to journal › Article
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Mark
Selective killing of candidate AML stem cells by antibody targeting of IL1RAP.
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- Contribution to journal › Article
- 2012
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Mark
SPARC is dispensable for murine hematopoiesis, despite its suspected pathophysiological role in 5q- myelodysplastic syndrome.
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- Contribution to journal › Article
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Mark
Targeting the hematopoietic stem cell to correct osteopetrosis
(
- Thesis › Doctoral thesis (compilation)
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Mark
Modeling Diamond-Blackfan Anemia in the Mouse: Disease Pathogenesis and Evaluation of Novel Therapies
(
- Thesis › Doctoral thesis (compilation)
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Mark
Molecular and cellular effects of oncogene cooperation in a genetically accurate AML mouse model.
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- Contribution to journal › Article
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Mark
Normal Hematopoietic Stem Cell Function in Mice with Enforced Expression of the Hippo Signaling Effector YAP1.
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- Contribution to journal › Article
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Mark
Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions
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- Contribution to journal › Article
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Mark
Killer-cell immunoglobulin-like receptor gene profile predicts good molecular response to dasatinib therapy in chronic myeloid leukemia
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- Contribution to journal › Article
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Mark
Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia.
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- Contribution to journal › Article
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Mark
Human hematopoietic stem/progenitor cells overexpressing Smad4 exhibit impaired reconstitution potential in vivo.
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- Contribution to journal › Article
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Mark
Hematopoietic stem cells are regulated by Cripto, as an intermediary of HIF-1α in the hypoxic bone marrow niche.
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- Contribution to journal › Article
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Mark
Progress towards Mechanism-Based Treatment for Diamond-Blackfan Anemia.
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- Contribution to journal › Article
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Mark
RNAi screen identifies MAPK14 as a druggable suppressor of human hematopoietic stem cell expansion.
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- Contribution to journal › Article
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Mark
Angptl4 maintains in vivo repopulation capacity of CD34(+) human cord blood cells.
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- Contribution to journal › Article
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Mark
Common signaling networks characterize leukemia-initiating cells in acute myeloid leukemia.
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- Contribution to journal › Article
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Mark
Murine ameloblasts are immunonegative for Tcirg1, the v-H-ATPase subunit essential for the osteoclast plasma proton pump
(
- Contribution to journal › Article
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Mark
Genetic modeling of the Hippo pathway in hematopoietic stem cells
(
- Thesis › Doctoral thesis (compilation)