Neurobiology
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- 2024
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Mark
Forced LMX1A expression induces dorsal neural fates and disrupts patterning of human embryonic stem cells into ventral midbrain dopaminergic neurons
(
- Contribution to journal › Article
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Mark
Structural and functional connectivity associations with anterior cingulate sulcal variability
2024) In Brain Structure and Function(
- Contribution to journal › Article
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Mark
A blood-based biomarker workflow for optimal tau-PET referral in memory clinic settings
(
- Contribution to journal › Article
- 2022
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Mark
The performance of plasma amyloid beta measurements in identifying amyloid plaques in Alzheimer's disease : a literature review
(
- Contribution to journal › Scientific review
- 2020
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Mark
Extensive clonal branching shapes the evolutionary history of high-risk pediatric cancers
(
- Contribution to journal › Article
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Mark
Plasma NT1 Tau is a Specific and Early Marker of Alzheimer's Disease
(
- Contribution to journal › Article
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Mark
Derivation and utility of an Aβ-PET pathology accumulation index to estimate Aβ load
(
- Contribution to journal › Article
- 2019
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Mark
Clinical value of cerebrospinal fluid neurofilament light chain in semantic dementia
(
- Contribution to journal › Article
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Mark
Towards a unified protocol for handling of CSF before β-amyloid measurements
(
- Contribution to journal › Article
- 2018
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Mark
Destabilizing Domains Enable Long-Term and Inert Regulation of GDNF Expression in the Brain
(
- Contribution to journal › Article
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Mark
Cerebral hypoperfusion is not associated with an increase in amyloid β pathology in middle-aged or elderly people
(
- Contribution to journal › Article
- 2017
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Mark
Replacing Dopamine Neurons in Parkinson's Disease : How did it happen?
(
- Contribution to journal › Scientific review
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Mark
Preface
(
- Chapter in Book/Report/Conference proceeding › Foreword/Postscript
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Mark
BDNF over-expression induces striatal serotonin fiber sprouting and increases the susceptibility to L-DOPA-induced dyskinesia in 6-OHDA-lesioned rats
(
- Contribution to journal › Article
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Mark
Preclinical effects of APOE ϵ4 on cerebrospinal fluid Aβ42 concentrations
(
- Contribution to journal › Article
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Mark
Mechanisms and use of neural transplants for brain repair
(
- Chapter in Book/Report/Conference proceeding › Book chapter
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Mark
Modeling Parkinson’s disease pathology by combination of fibril seeds and α-synuclein overexpression in the rat brain
2017) In Proceedings of the National Academy of Sciences of the United States of America 114(39). p.8284-8293(
- Contribution to journal › Article
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Mark
Preface
(
- Chapter in Book/Report/Conference proceeding › Foreword/Postscript
- 2016
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Mark
DREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor
(
- Contribution to journal › Article
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Mark
α-Synuclein induced toxicity in brain stem serotonin neurons mediated by an AAV vector driven by the tryptophan hydroxylase promoter
(
- Contribution to journal › Article
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Mark
Brain activity and Alzheimer's disease : A complex relationship
(
- Contribution to journal › Debate/Note/Editorial
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Mark
Extensive graft-derived dopaminergic innervation is maintained 24 years after transplantation in the degenerating parkinsonian brain.
2016) In Proceedings of the National Academy of Sciences of the United States of America 113(23). p.6544-6549(
- Contribution to journal › Article
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Mark
Emotional memory impairments induced by AAV-mediated overexpression of human α-synuclein in dopaminergic neurons of the ventral tegmental area.
(
- Contribution to journal › Article
- 2015
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Mark
Identification of the miRNA targetome in hippocampal neurons using RIP-seq.
(
- Contribution to journal › Article
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Mark
Transposable Elements in Neural Progenitor Cells
(
- Thesis › Doctoral thesis (compilation)
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Mark
Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons.
(
- Contribution to journal › Article
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Mark
Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson's disease: a dose-finding study.
(
- Contribution to journal › Article
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Mark
Reconstruction of brain circuitry by neural transplants generated from pluripotent stem cells.
(
- Contribution to journal › Scientific review
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Mark
Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor.
(
- Contribution to journal › Article
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Mark
Nurr1 and Retinoid X Receptor Ligands Stimulate Ret Signaling in Dopamine Neurons and Can Alleviate α-Synuclein Disrupted Gene Expression.
(
- Contribution to journal › Article
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Mark
Depressive-like phenotype induced by AAV-mediated overexpression of human α-synuclein in midbrain dopaminergic neurons.
(
- Contribution to journal › Article
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Mark
Parkinson's Disease Case Ascertainment in the EPIC Cohort: The NeuroEPIC4PD Study
(
- Contribution to journal › Article
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Mark
The role of pallidal serotonergic function in Parkinson's disease dyskinesias: a positron emission tomography study.
(
- Contribution to journal › Article
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Mark
Transcriptome analysis reveals transmembrane targets on transplantable midbrain dopamine progenitors.
(
- Contribution to journal › Article
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Mark
GDNF is not required for catecholaminergic neuron survival in vivo.
(
- Contribution to journal › Letter
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Mark
Alpha-Synuclein Produces Early Behavioral Alterations Via Striatal Cholinergic Synaptic Dysfunction by Interacting with GluN2D N-Methyl-D-Aspartate Receptor Subunit.
2015) In Biological Psychiatry(
- Contribution to journal › Article
- 2014
-
Mark
Generation of induced neurons via direct conversion in vivo and in vitro
(
- Thesis › Doctoral thesis (compilation)
-
Mark
The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons
(
- Contribution to journal › Article
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Mark
Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson's Disease.
(
- Contribution to journal › Article
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Mark
Dynamic changes in dopamine neuron function after DNSP-11 treatment: Effects in vivo and increased ERK 1/2 phosphorylation in vitro.
(
- Contribution to journal › Article
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Mark
microRNA-125 distinguishes developmentally generated and adult-born olfactory bulb interneurons.
(
- Contribution to journal › Article
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Mark
The anti-dyskinetic effect of dopamine receptor blockade is enhanced in parkinsonian rats following dopamine neuron transplantation.
(
- Contribution to journal › Article
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Mark
Noradrenaline neuron degeneration contributes to motor impairments and development of L-DOPA-induced dyskinesia in a rat model of Parkinson's disease.
(
- Contribution to journal › Article
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Mark
Long-term clinical outcome of fetal cell transplantation for Parkinson disease : two case reports
(
- Contribution to journal › Article
- 2013
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Mark
Anti-dyskinetic effect of anpirtoline in animal models of L-DOPA-induced dyskinesia
(
- Contribution to journal › Article
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Mark
Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons
(
- Contribution to journal › Article
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Mark
TFEB: Pathogenic role and therapeutic target in Parkinson disease.
(
- Contribution to journal › Article
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Mark
Study of the antidyskinetic effect of eltoprazine in animal models of levodopa-induced dyskinesia
(
- Contribution to journal › Article
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Mark
Generation of induced neurons via direct conversion in vivo.
(
- Contribution to journal › Article
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Mark
mTOR Inhibition Alleviates L-DOPA-Induced Dyskinesia in Parkinsonian Rats
(
- Contribution to journal › Article
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Mark
NURR1 in Parkinson disease-from pathogenesis to therapeutic potential.
(
- Contribution to journal › Scientific review
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Mark
Trophic Factor Gene Therapy for Parkinson's Disease
(
- Contribution to journal › Scientific review
-
Mark
TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity.
(
- Contribution to journal › Article
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Mark
Region-specific restoration of striatal synaptic plasticity by dopamine grafts in experimental parkinsonism.
(
- Contribution to journal › Article
-
Mark
Human foetal brain tissue as quality control when developing stem cells towards cell replacement therapy for neurological diseases.
(
- Contribution to journal › Article
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Mark
Cell therapy for Parkinson's disease: what next?
(
- Contribution to journal › Article
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Mark
A novel α-synuclein-GFP mouse model displays progressive motor impairment, olfactory dysfunction and accumulation of α-synuclein-GFP.
(
- Contribution to journal › Article
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Mark
Fetal dopaminergic transplantation trials and the future of neural grafting in Parkinson's disease
(
- Contribution to journal › Scientific review
- 2012
-
Mark
CELL REPLACEMENT THERAPY FOR PARKINSON’S DISEASE: The importance of neuronal subtype, cell source and connectivity for functional recovery
(
- Thesis › Doctoral thesis (compilation)
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Mark
Generation of Regionally Specified Neural Progenitors and Functional Neurons from Human Embryonic Stem Cells under Defined Conditions.
(
- Contribution to journal › Article
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Mark
Impaired neurotransmission caused by overexpression of α-synuclein in nigral dopamine neurons.
(
- Contribution to journal › Article
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Mark
Progressive neurodegenerative and behavioural changes induced by AAV-mediated overexpression of α-synuclein in midbrain dopamine neurons.
(
- Contribution to journal › Article
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Mark
Serotonin Neuron Loss and Nonmotor Symptoms Continue in Parkinson's Patients Treated with Dopamine Grafts
(
- Contribution to journal › Article
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Mark
Role of Serotonin Neurons in L-DOPA- and Graft-Induced Dyskinesia in a Rat Model of Parkinson's Disease.
(
- Contribution to journal › Scientific review
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Mark
α-Synuclein-Induced Down-Regulation of Nurr1 Disrupts GDNF Signaling in Nigral Dopamine Neurons.
(
- Contribution to journal › Article
-
Mark
Comparison of the behavioural and histological characteristics of the 6-OHDA and alpha-synuclein rat models of Parkinson's disease
(
- Contribution to journal › Article
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Mark
Alpha-Synuclein Cell-to-Cell Transfer and Seeding in Grafted Dopaminergic Neurons In Vivo.
(
- Contribution to journal › Article
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Mark
Serotonergic and dopaminergic mechanisms in graft-induced dyskinesia in a rat model of Parkinson's disease.
(
- Contribution to journal › Article
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Mark
Neuropeptide Y and its role in CNS disease and repair.
(
- Contribution to journal › Article
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Mark
Generation of Transplantable Striatal Projection Neurons from Human ESCs.
(
- Contribution to journal › Article
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Mark
Amphetamine-induced rotation and l-DOPA-induced dyskinesia in the rat 6-OHDA model: A correlation study.
(
- Contribution to journal › Article
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Mark
Profile of Anders Bjorklund. Interview by Beth Azar
2012) In Proceedings of the National Academy of Sciences of the United States of America 109(33). p.9-13137(
- Contribution to journal › Article
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Mark
Introduction (Part I)
(
- Chapter in Book/Report/Conference proceeding › Book chapter
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Mark
Introduction (Part II)
(
- Chapter in Book/Report/Conference proceeding › Book chapter
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Mark
Survival, differentiation, and connectivity of ventral mesencephalic dopamine neurons following transplantation
(
- Chapter in Book/Report/Conference proceeding › Book chapter
- 2011
-
Mark
GDNF fails to exert neuroprotection in a rat {alpha}-synuclein model of Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Graft-Induced Dyskinesias in Parkinson's Disease: High Striatal Serotonin/Dopamine Transporter Ratio
(
- Contribution to journal › Article
-
Mark
Higher free d-aspartate and N-methyl-d-aspartate levels prevent striatal depotentiation and anticipate 1-DOPA-induced dyskinesia
(
- Contribution to journal › Article
-
Mark
Cell Therapeutics in Parkinson's Disease.
(
- Contribution to journal › Article
-
Mark
Gene therapy for Parkinson's disease shows promise.
(
- Contribution to journal › Article
-
Mark
Lineage reprogramming: A shortcut to generating functional neurons from fibroblasts.
(
- Contribution to journal › Article
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Mark
Direct conversion of human fibroblasts to dopaminergic neurons.
(
- Contribution to journal › Article
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Mark
Contribution of pre-synaptic mechanisms to l-DOPA-induced dyskinesia.
(
- Contribution to journal › Article
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Mark
Dopamine release from serotonergic nerve fibers is reduced in L-DOPA-induced dyskinesia.
(
- Contribution to journal › Article
- 2010
-
Mark
Recent Advances In Parkinson'S Disease: Translational And Clinical Research Preface
(
- Contribution to journal › Debate/Note/Editorial
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Mark
Gli1 Is an Inducing Factor in Generating Floor Plate Progenitor Cells from Human Embryonic Stem Cells
(
- Contribution to journal › Article
-
Mark
Neural grafting in Parkinson's disease: unraveling the mechanisms underlying graft-induced dyskinesia
(
- Contribution to journal › Scientific review
-
Mark
Neural grafting in Parkinson's disease: problems and possibilities
(
- Contribution to journal › Scientific review
-
Mark
Viral vector-mediated overexpression of α-synuclein as a progressive model of Parkinson's disease
(
- Contribution to journal › Scientific review
-
Mark
FoxP1 promotes midbrain identity in embryonic stem cell-derived dopamine neurons by regulating Pitx3
(
- Contribution to journal › Article
-
Mark
Role of Aberrant Striatal Dopamine D-1 Receptor/cAMP/Protein Kinase A/DARPP32 Signaling in the Paradoxical Calming Effect of Amphetamine
(
- Contribution to journal › Article
-
Mark
The Role of Norepinephrine Neurons in Motor Symptoms of Parkinson's Disease and Development of L-DOPA-Induced Dyskinesia
(
- Contribution to journal › Published meeting abstract
-
Mark
Characterization of Lewy Body Pathology in 12-and 16-Year Old Intrastriatal Mesencephalic Grafts Surviving in a Patient with Parkinson's Disease
(
- Contribution to journal › Published meeting abstract
-
Mark
Characterization of Lewy body pathology in 12- and 16-year-old intrastriatal mesencephalic grafts surviving in a patient with Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Glial Cell Derived Neurotrophic Factor Does not Provide Neuroprotection Against Alpha-Synuclein-Induced Toxicity in a Rat Model of Parkinson's Disease
(
- Contribution to journal › Published meeting abstract
-
Mark
The A9 dopamine neuron component in grafts of ventral mesencephalon is an important determinant for recovery of motor function in a rat model of Parkinson's disease
(
- Contribution to journal › Article
-
Mark
Role of Serotonin Neurons in the Development of L-DOPA-Induced Dyskinesias
(
- Contribution to journal › Published meeting abstract
-
Mark
Characterisation of Behavioural and Neurodegenerative Changes Induced by Intranigral 6-Hydroxydopamine Lesions in a Mouse Model of Parkinson's Disease
(
- Contribution to journal › Published meeting abstract
-
Mark
New Mouse Models for Studying Postnatal Role of GDNF In Vivo
2010) 17th Annual Meeting of the American-Society-for-Neural-Therapy-and-Repair In Cell Transplantation 19(3). p.331-331(
- Contribution to journal › Published meeting abstract
-
Mark
Serotonergic Neurons Mediate Dyskinesia Side Effects in Parkinson's Patients with Neural Transplants
(
- Contribution to journal › Article