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- 2024
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Mark
Sub-Nanomolar Detection of Oligonucleotides Using Molecular Beacons Immobilized on Lightguiding Nanowires
(
- Contribution to journal › Article
-
Mark
Current and emerging sequencing-based tools for precision cancer medicine
(
- Contribution to journal › Scientific review
-
Mark
Precision Diagnostics in Myeloid Malignancies : Development and Validation of a National Capture-Based Gene Panel
(
- Contribution to journal › Article
-
Mark
Constitutional and acquired genetic variants in ARID5B in pediatric B-cell precursor acute lymphoblastic leukemia
(
- Contribution to journal › Article
-
Mark
Antibodies targeting the shared cytokine receptor IL-1 receptor accessory protein invoke distinct mechanisms to block all cytokine signaling
2024) In Cell Reports(
- Contribution to journal › Article
-
Mark
Distinct Infiltration of T Cell Populations in Bladder Cancer Molecular Subtypes
(
- Contribution to journal › Article
- 2023
-
Mark
Multimodal classification of molecular subtypes in pediatric acute lymphoblastic leukemia
(
- Contribution to journal › Article
-
Mark
Combined GLUT1 and OXPHOS inhibition eliminates acute myeloid leukemia cells by restraining their metabolic plasticity
(
- Contribution to journal › Article
-
Mark
Novel precision medicine approaches and treatment strategies in hematological malignancies
(
- Contribution to journal › Scientific review
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Mark
Feasibility to use whole-genome sequencing as a sole diagnostic method to detect genomic aberrations in pediatric B-cell acute lymphoblastic leukemia
(
- Contribution to journal › Article
-
Mark
IL1RAP is expressed in several subtypes of pediatric acute lymphoblastic leukemia and can be used as a target to eliminate
ETV6::RUNX1-positive leukemia cells in preclinical models.
(
- Contribution to journal › Article
-
Mark
Building a precision medicine infrastructure at a national level: The Swedish experience
(
- Contribution to journal › Scientific review
-
Mark
The complement receptor C3AR constitutes a novel therapeutic target in NPM1-mutated AML
(
- Contribution to journal › Article
- 2022
-
Mark
Trailblazing precision medicine in Europe : A joint view by Genomic Medicine Sweden and the Centers for Personalized Medicine, ZPM, in Germany
(
- Contribution to journal › Article
-
Mark
N-terminus DUX4-immunohistochemistry is a reliable methodology for the diagnosis of DUX4-fused B-lymphoblastic leukemia/lymphoma (N-terminus DUX4 IHC for DUX4-fused B-ALL)
(
- Contribution to journal › Article
-
Mark
Implementing precision medicine in a regionally organized healthcare system in Sweden
(
- Contribution to journal › Letter
-
Mark
A Study Protocol for Validation and Implementation of Whole-Genome and -Transcriptome Sequencing as a Comprehensive Precision Diagnostic Test in Acute Leukemias
(
- Contribution to journal › Article
-
Mark
Inducing synthetic lethality for selective targeting of acute myeloid leukemia cells harboring STAG2 mutations
(
- Contribution to journal › Letter
-
Mark
Enhanced Optical Biosensing by Aerotaxy Ga(As)P Nanowire Platforms Suitable for Scalable Production
2022) In ACS Applied Nano Materials(
- Contribution to journal › Article
-
Mark
High CD34 surface expression in BCP-ALL predicts poor induction therapy response and is associated with altered expression of genes related to cell migration and adhesion
(
- Contribution to journal › Article
-
Mark
Why B(-)other? About the gap of unknowns in ALL
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Transcriptional profiling demonstrates altered characteristics of CD8 + cytotoxic T-cells and regulatory T-cells in TP53-mutated acute myeloid leukemia
(
- Contribution to journal › Article
-
Mark
Application of precision medicine in clinical routine in haematology—Challenges and opportunities
(
- Contribution to journal › Scientific review
-
Mark
Transcriptomics paving the way for improved diagnostics and precision medicine of acute leukemia
(
- Contribution to journal › Article
- 2021
-
Mark
Single-cell sequencing in translational cancer research and challenges to meet clinical diagnostic needs
(
- Contribution to journal › Scientific review
-
Mark
Clinical and genomic characterization of patients diagnosed with the provisional entity Acute myeloid leukemia with BCR-ABL1, a Swedish population-based study
(
- Contribution to journal › Article
-
Mark
Combinatorial molecule screening identifies a novel diterpene and the BET inhibitor CPI-203 as differentiation inducers of primary acute myeloid leukemia cells
(
- Contribution to journal › Article
-
Mark
Precisionsmedicin standard vid flera hematologiska sjukdomar
(
- Contribution to journal › Article
- 2020
-
Mark
Clonal competition within complex evolutionary hierarchies shapes AML over time
(
- Contribution to journal › Article
-
Mark
13q12.2 deletions in acute lymphoblastic leukemia lead to upregulation of FLT3 through enhancer hijacking
(
- Contribution to journal › Article
-
Mark
A high-content cytokine screen identifies myostatin propeptide as a positive regulator of primitive chronic myeloid leukemia cells
(
- Contribution to journal › Article
-
Mark
Transcriptomic profiling of T-cell populations in non-muscle invasive and muscle invasive bladder cancer.
2020) The Society for Immunotherapy of Cancer's (SITC) 35th annual meeting In Journal for ImmunoTherapy of Cancer 8(Suppl. 3).(
- Contribution to journal › Published meeting abstract
- 2019
-
Mark
Proteogenomics and Hi-C reveal transcriptional dysregulation in high hyperdiploid childhood acute lymphoblastic leukemia
(
- Contribution to journal › Article
-
Mark
PAX5 is part of a functional transcription factor network targeted in lymphoid leukemia
(
- Contribution to journal › Article
-
Mark
Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells
(
- Contribution to journal › Article
-
Mark
Genetic profiling of a chondroblastoma-like osteosarcoma/malignant phosphaturic mesenchymal tumor of bone reveals a homozygous deletion of CDKN2A, intragenic deletion of DMD, and a targetable FN1-FGFR1 gene fusion
(
- Contribution to journal › Article
- 2018
-
Mark
Mutation, methylation, and gene expression profiles in dup(1q)-positive pediatric B-cell precursor acute lymphoblastic leukemia
(
- Contribution to journal › Article
-
Mark
CD36 defines primitive chronic myeloid leukemia cells less responsive to imatinib but vulnerable to antibody-based therapeutic targeting
(
- Contribution to journal › Article
-
Mark
Transcriptional landscape of B cell precursor acute lymphoblastic leukemia based on an international study of 1,223 cases
2018) In Proceedings of the National Academy of Sciences of the United States of America 115(50). p.11711-11720(
- Contribution to journal › Article
-
Mark
Whole-exome sequencing exploration of acquired uniparental disomies in B-cell precursor acute lymphoblastic leukemia
(
- Contribution to journal › Article
-
Mark
Isolated myelosarcoma is characterized by recurrent NFE2 mutations and concurrent preleukemic clones in the bone marrow
(
- Contribution to journal › Letter
-
Mark
Interleukin 4 induces apoptosis of acute myeloid leukemia cells in a Stat6 dependent manner
(
- Contribution to journal › Article
-
Mark
A field guide for cancer diagnostics using cell-free DNA : From principles to practice and clinical applications
(
- Contribution to journal › Scientific review
- 2017
-
Mark
Gain-of-function SAMD9L mutations cause a syndrome of cytopenia, immunodeficiency, MDS and neurological symptoms
(
- Contribution to journal › Article
-
Mark
Distinct global binding patterns of the Wilms' tumor gene 1 (WT1) -KTS and +KTS isoforms in leukemic cells
(
- Contribution to journal › Article
-
Mark
Agonistic targeting of TLR1/TLR2 induces p38 MAPK-dependent apoptosis and NFκB-dependent differentiation of AML cells
(
- Contribution to journal › Article
-
Mark
Transgenic expression of human cytokines in immunodeficient mice does not facilitate myeloid expansion of BCR-ABL1 transduced human cord blood cells
(
- Contribution to journal › Article
-
Mark
New oncogenic subtypes in pediatric B-cell precursor acute lymphoblastic leukemia
(
- Contribution to journal › Scientific review
-
Mark
Loss of the tumor suppressor gene AIP mediates the browning of human brown fat tumors
(
- Contribution to journal › Article
- 2016
-
Mark
IL1RAP antibodies block IL-1-induced expansion of candidate CML stem cells and mediate cell killing in xenograft models
(
- Contribution to journal › Article
-
Mark
Clonal conversion of B lymphoid leukemia reveals cross-lineage transfer of malignant states
(
- Contribution to journal › Article
-
Mark
Leukemic stem cell quantification in newly diagnosed chronic myeloid leukemia patients predicts response to nilotinib therapy
(
- Contribution to journal › Article
-
Mark
Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia
(
- Contribution to journal › Article
- 2015
-
Mark
Intratumoral genome diversity parallels progression and predicts outcome in pediatric cancer.
(
- Contribution to journal › Article
-
Mark
IL1RAP expression as a measure of leukemic stem cell burden at diagnosis of chronic myeloid leukemia predicts therapy outcome.
(
- Contribution to journal › Article
-
Mark
The genomic landscape of high hyperdiploid childhood acute lymphoblastic leukemia.
(
- Contribution to journal › Article
-
Mark
Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia.
(
- Contribution to journal › Article
-
Mark
Deep sequencing and SNP array analyses of pediatric T-cell acute lymphoblastic leukemia reveal NOTCH1 mutations in minor subclones and a high incidence of uniparental isodisomies affecting CDKN2A.
(
- Contribution to journal › Article
-
Mark
Ebf1 heterozygosity results in increased DNA damage in pro-B cells and their synergistic transformation by Pax5 haploinsufficiency.
(
- Contribution to journal › Article
-
Mark
The emerging complexity of gene fusions in cancer.
(
- Contribution to journal › Scientific review
-
Mark
The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias.
(
- Contribution to journal › Article
-
Mark
Activation of human telomerase reverse transcriptase through gene fusion in clear cell sarcoma of the kidney.
(
- Contribution to journal › Article
-
Mark
Chronic myeloid leukemia
2015) p.153-174(
- Chapter in Book/Report/Conference proceeding › Book chapter
- 2014
-
Mark
Modeling chronic myeloid leukemia in immunodeficient mice reveals expansion of aberrant mast cells and accumulation of pre-B cells.
(
- Contribution to journal › Article
-
Mark
RNA-seq identifies clinically relevant fusion genes in leukemia including a novel MEF2D/CSF1R fusion responsive to imatinib.
(
- Contribution to journal › Letter
-
Mark
Fusions involving protein kinase C and membrane-associated proteins in benign fibrous histiocytoma.
(
- Contribution to journal › Article
-
Mark
A novel SERPINE1-FOSB fusion gene results in transcriptional up-regulation of FOSB in pseudomyogenic haemangioendothelioma.
(
- Contribution to journal › Article
-
Mark
A glioma classification scheme based on coexpression modules of EGFR and PDGFRA
2014) In Proceedings of the National Academy of Sciences of the United States of America 111(9). p.3538-3543(
- Contribution to journal › Article
-
Mark
Comprehensive genetic characterization of pediatric T-cell acute lymphoblastic leukemia
(
- Contribution to journal › Published meeting abstract
- 2013
-
Mark
SOCS2 is dispensable for BCR/ABL1-induced chronic myeloid leukemia-like disease and for normal hematopoietic stem cell function.
(
- Contribution to journal › Article
-
Mark
Impact of malignant stem cell burden on therapy outcome in newly diagnosed chronic myeloid leukemia patients
(
- Contribution to journal › Article
-
Mark
Selective killing of candidate AML stem cells by antibody targeting of IL1RAP.
(
- Contribution to journal › Article
- 2012
-
Mark
Whole-exome sequencing of pediatric acute lymphoblastic leukemia.
(
- Contribution to journal › Article
-
Mark
Myeloid malignancies with acquired trisomy 21 as the sole cytogenetic change are clinically highly variable and display a heterogeneous pattern of copy number alterations and mutations(a).
(
- Contribution to journal › Article
- 2011
-
Mark
Fusion Gene Microarray Reveals Cancer Type-Specificity Among Fusion Genes
(
- Contribution to journal › Article
-
Mark
SMAD4 binds HOXA9 in the cytoplasm and protects primitive hematopoietic cells against nuclear activation by HOXA9 and leukemia transformation.
(
- Contribution to journal › Article
- 2010
-
Mark
Integrative analysis of gene expression and copy number alterations using canonical correlation analysis
(
- Contribution to journal › Article
-
Mark
The correlation pattern of acquired copy number changes in 164 ETV6/RUNX1-positive childhood acute lymphoblastic leukemias
(
- Contribution to journal › Article
-
Mark
The Proportion of Ph+CD34(+)CD38(neg) Leukemic Stem Cells In the Bone Marrow of Newly Diagnosed Patients with Chronic Myeloid Leukemia (CML) In Chronic Phase (CP) Is Variable and Correlates with High Sokal Risk, High Leukocyte Count, Low Hemoglobin Concentration, Splenomegaly and Increased Hematological Toxicity During Initial TKI Therapy Data From a Randomized Phase II NordCML006 Study
(
- Contribution to journal › Published meeting abstract
-
Mark
Modeling the human 8p11-myeloproliferative syndrome in immunodeficient mice
(
- Contribution to journal › Article
-
Mark
SMAD4 Sequestrates HOXA9 to Protect Hematopoietic Stem Cells Against Leukemia Transformation
(
- Contribution to journal › Published meeting abstract
-
Mark
Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein.
(
- Contribution to journal › Article
-
Mark
Gene expression signatures in childhood acute leukemias are largely unique and distinct from those of normal tissues and other malignancies.
(
- Contribution to journal › Article
-
Mark
Genetic analysis of dasatinib-treated chronic myeloid leukemia rapidly developing into acute myeloid leukemia with monosomy 7 in Philadelphia-negative cells.
(
- Contribution to journal › Article
-
Mark
Relapsed childhood high hyperdiploid acute lymphoblastic leukemia: presence of preleukemic ancestral clones and the secondary nature of microdeletions and RTK-RAS mutations.
(
- Contribution to journal › Article
- 2009
-
Mark
Expression of P190 and P210 BCR/ABL1 in normal human CD34(+) cells induces similar gene expression profiles and results in a STAT5-dependent expansion of the erythroid lineage
(
- Contribution to journal › Article
-
Mark
Relapsed Childhood High Hyperdiploid Acute Lymphoblastic Leukemia: Genome-Wide Screening Reveals the Presence of Preleukemic Ancestral Clones and the Secondary Nature of Microdeletions and RTK-RAS Mutations
(
- Contribution to journal › Published meeting abstract
-
Mark
SMAD4 as a therapeutic target in hoxa9-related leukemia
2009) 38th Annual Scientific Meeting of the ISEH-Society-for-Hematology-and-Stem-Cells In Experimental Hematology 37(9). p.44-45(
- Contribution to journal › Published meeting abstract
-
Mark
The DNA methylome of pediatric acute lymphoblastic leukemia.
(
- Contribution to journal › Article
-
Mark
The t(X;7)(q22;q34) in paediatric T-cell acute lymphoblastic leukaemia results in overexpression of the insulin receptor substrate 4 gene through illegitimate recombination with the T-cell receptor beta locus.
(
- Contribution to journal › Article
- 2008
-
Mark
Gene expression analysis of BCR/ABL1-dependent transcriptional response reveals enrichment for genes involved in negative feedback regulation.
(
- Contribution to journal › Article
-
Mark
An improved method for detecting and delineating genomic regions with altered gene expression in cancer
(
- Contribution to journal › Article
-
Mark
Mutations of FLT3, NRAS, KRAS, and PTPN11 are frequent and possibly mutually exclusive in high hyperdiploid childhood acute lymphoblastic leukemia
(
- Contribution to journal › Article
-
Mark
The hypermethylome of pediatric acute lymphoblastic leukemia
(
- Contribution to journal › Published meeting abstract
-
Mark
The FLT3 inhibitor PKC412 in combination with cytostatic drugs in vitro in acute myeloid leukemia
(
- Contribution to journal › Article
-
Mark
FLT3 mutations in a 10 year consecutive series of 177 childhood acute leukemias and their impact on global gene expression patterns.
(
- Contribution to journal › Article
-
Mark
Recurrent and multiple bladder tumors show conserved expression profiles.
(
- Contribution to journal › Article
-
Mark
BRAF mutations are very rare in B- and T-cell pediatric acute lymphoblastic leukemias.
(
- Contribution to journal › Article
- 2007
-
Mark
Threshold-free high-power methods for the ontological analysis of genome-wide gene expression studies
(
- Contribution to journal › Article
-
Mark
Fusion gene-mediated truncation of RUNX1 as a potential mechanism underlying disease progression in the 8p11 myeloproliferative syndrome.
(
- Contribution to journal › Article