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- 2023
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Mark
Type 2 diabetes candidate genes, including PAX5, cause impaired insulin secretion in human pancreatic islets
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- Contribution to journal › Article
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Mark
Circulating triglycerides are associated with human adipose tissue DNA methylation of genes linked to metabolic disease
(
- Contribution to journal › Article
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Mark
DNA methylation partially mediates antidiabetic effects of metformin on HbA1c levels in individuals with type 2 diabetes
(
- Contribution to journal › Article
- 2022
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Mark
Novel Subgroups of Type 2 Diabetes Display Different Epigenetic Patterns, Which Associate With Future Diabetic Complications
(
- Contribution to journal › Article
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Mark
Type 2 diabetes classification : a data-driven cluster study of the Danish Centre for Strategic Research in Type 2 Diabetes (DD2) cohort
(
- Contribution to journal › Article
- 2021
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Mark
VPS39-deficiency observed in type 2 diabetes impairs muscle stem cell differentiation via altered autophagy and epigenetics
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- Contribution to journal › Article
- 2020
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Mark
Epigenetic markers associated with metformin response and intolerance in drug-naïve patients with type 2 diabetes
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- Contribution to journal › Article
- 2017
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Mark
HDAC7 is overexpressed in human diabetic islets and impairs insulin secretion in rat islets and clonal beta cells
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- Contribution to journal › Article
- 2016
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Mark
A genome-wide mQTL analysis in human adipose tissue identifies genetic variants associated with DNA methylation, gene expression and metabolic traits
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- Contribution to journal › Article
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Mark
A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes
(
- Contribution to journal › Article
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Mark
Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes
(
- Contribution to journal › Article
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Mark
NIH working group report-using genomic information to guide weight management: From universal to precision treatment.
(
- Contribution to journal › Scientific review
- 2015
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Mark
Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood.
(
- Contribution to journal › Article
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Mark
Less pronounced response to exercise in healthy relatives to type 2 diabetics compared to controls.
(
- Contribution to journal › Article
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Mark
Genome-wide analysis of DNA methylation in subjects with type 1 diabetes identifies epigenetic modifications associated with proliferative diabetic retinopathy.
(
- Contribution to journal › Article
- 2014
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Mark
Sex differences in the genome-wide DNA methylation pattern and impact on gene expression, microRNA levels and insulin secretion in human pancreatic islets
(
- Contribution to journal › Article
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Mark
Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion.
(
- Contribution to journal › Article
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Mark
Extensive changes in the transcriptional profile of human adipose tissue including genes involved in oxidative phosphorylation after a six months exercise intervention.
(
- Contribution to journal › Article
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Mark
Genome-Wide Associations between Genetic and Epigenetic Variation Influence mRNA Expression and Insulin Secretion in Human Pancreatic Islets.
(
- Contribution to journal › Article
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Mark
A Central Role for GRB10 in Regulation of Islet Function in Man.
(
- Contribution to journal › Article
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Mark
Altered DNA methylation and differential expression of genes influencing metabolism and inflammation in adipose tissue from subjects with type 2 diabetes.
(
- Contribution to journal › Article
- 2013
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Mark
DNA methylation of the glucagon-like peptide 1 receptor (GLP1R) in human pancreatic islets.
(
- Contribution to journal › Article
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Mark
Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets.
(
- Contribution to journal › Article
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Mark
A six months exercise intervention influences the genome-wide DNA methylation pattern in human adipose tissue.
(
- Contribution to journal › Article
- 2012
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Mark
A Single Nucleotide Polymorphism Associates With the Response of Muscle ATP Synthesis to Long-Term Exercise Training in Relatives of Type 2 Diabetic Humans
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- Contribution to journal › Article
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Mark
First-Degree Relatives of Type 2 Diabetic Patients Have Reduced Expression of Genes Involved in Fatty Acid Metabolism in Skeletal Muscle.
(
- Contribution to journal › Article
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Mark
Effects of short-term high-fat overfeeding on genome-wide DNA methylation in the skeletal muscle of healthy young men
(
- Contribution to journal › Article
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Mark
Increased DNA Methylation and Decreased Expression of PDX-1 in Pancreatic Islets from Patients with Type 2 Diabetes.
(
- Contribution to journal › Article
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Mark
Reduced insulin secretion correlates with decreased expression of exocytotic genes in pancreatic islets from patients with type 2 diabetes.
(
- Contribution to journal › Article
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Mark
Impact of an Exercise Intervention on DNA Methylation in Skeletal Muscle From First-Degree Relatives of Patients With Type 2 Diabetes.
2012) In Diabetes(
- Contribution to journal › Article
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Mark
Telomere length in blood and skeletal muscle in relation to measures of glycaemia and insulinaemia.
(
- Contribution to journal › Article
- 2011
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Mark
A common variant near the PRL gene is associated with increased adiposity in males
(
- Contribution to journal › Article
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Mark
Maternal diet and aging alter the epigenetic control of a promoter-enhancer interaction at the Hnf4a gene in rat pancreatic islets
(
- Contribution to journal › Article
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Mark
A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes.
(
- Contribution to journal › Article
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Mark
Decreased expression of genes involved in oxidative phosphorylation in human pancreatic islets from patients with type 2 diabetes.
(
- Contribution to journal › Article
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Mark
Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA(1c) levels in human pancreatic islets.
(
- Contribution to journal › Article
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Mark
The expression of myosin heavy chain (MHC) genes in human skeletal muscle is related to metabolic characteristics involved in the pathogenesis of type 2 diabetes.
(
- Contribution to journal › Article
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Mark
Genetic variation in the GCKR gene is associated with non-alcoholic fatty liver disease in Chinese people
(
- Contribution to journal › Article
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Mark
Two common genetic variants near nuclear encoded OXPHOS genes are associated with insulin secretion in vivo.
(
- Contribution to journal › Article
- 2010
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Mark
Epigenetics and obesity: the devil is in the details
(
- Contribution to journal › Debate/Note/Editorial
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Mark
THE ROLE OF SNARE PROTEINS IN HUMAN INSULIN RESISTANCE
2010) 78th Congress of the European-Atherosclerosis-Society In Atherosclerosis Supplements 11(2). p.283-283(
- Contribution to journal › Published meeting abstract
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Mark
Investigation of Type 2 Diabetes Risk Alleles Support CDKN2A/B, CDKAL1, and TCF7L2 As Susceptibility Genes in a Han Chinese Cohort
(
- Contribution to journal › Article
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Mark
The SNARE Protein SNAP23 and the SNARE-Interacting Protein Munc18c in Human Skeletal Muscle Are Implicated in Insulin Resistance/Type 2 Diabetes
(
- Contribution to journal › Article
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Mark
Resistance to exercise-induced changes in the global DNA methylation pattern of skeletal muscle in individuals with a family history of type 2 diabetes
2010) 46th Annual Meeting of the European-Association-for-the- Study-of-Diabetes (EASD) In Diabetologia 53(Suppl. 1). p.312-312(
- Contribution to journal › Published meeting abstract
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Mark
A mRNA marker for glycolytic muscle fibres may be used to determine fibre type composition in human skeletal muscle
2010) 46th Annual Meeting of the European-Association-for-the- Study-of-Diabetes (EASD) In Diabetologia 53(Suppl. 1). p.705-705(
- Contribution to journal › Published meeting abstract
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Mark
A lipotoxicity model in the INS-1 832/13 beta cell line and the epigenetic alterations induced by it
2010) 46th Annual Meeting of the European-Association-for-the- Study-of-Diabetes (EASD) In Diabetologia 53(Suppl. 1). p.348-348(
- Contribution to journal › Published meeting abstract
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Mark
Nesfatin-1 stimulates insulin secretion, inhibits glucagon secretion and is expressed in human and rodent beta cells
2010) 46th Annual Meeting of the European-Association-for-the- Study-of-Diabetes (EASD) In Diabetologia 53(Suppl. 1). p.548-548(
- Contribution to journal › Published meeting abstract
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Mark
Deoxyribonucleic Acid Methylation and Gene Expression of PPARGC1A in Human Muscle Is Influenced by High-Fat Overfeeding in a Birth-Weight-Dependent Manner.
(
- Contribution to journal › Article
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Mark
The Association of Mitochondrial Content with Prevalent and Incident Type 2 Diabetes.
(
- Contribution to journal › Article
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Mark
Elevated Serum Chemokine CXC Ligand 5 Levels Are Associated with Hypercholesterolemia But Not a Worsening of Insulin Resistance in Chinese People.
(
- Contribution to journal › Article