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- 2023
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Circulating triglycerides are associated with human adipose tissue DNA methylation of genes linked to metabolic disease
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- Contribution to journal › Article
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DNA methylation partially mediates antidiabetic effects of metformin on HbA1c levels in individuals with type 2 diabetes
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- Contribution to journal › Article
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Type 2 diabetes candidate genes, including PAX5, cause impaired insulin secretion in human pancreatic islets
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- Contribution to journal › Article
- 2022
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Type 2 diabetes classification : a data-driven cluster study of the Danish Centre for Strategic Research in Type 2 Diabetes (DD2) cohort
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- Contribution to journal › Article
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Novel Subgroups of Type 2 Diabetes Display Different Epigenetic Patterns, Which Associate With Future Diabetic Complications
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- Contribution to journal › Article
- 2021
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VPS39-deficiency observed in type 2 diabetes impairs muscle stem cell differentiation via altered autophagy and epigenetics
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- Contribution to journal › Article
- 2020
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Epigenetic markers associated with metformin response and intolerance in drug-naïve patients with type 2 diabetes
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- Contribution to journal › Article
- 2017
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HDAC7 is overexpressed in human diabetic islets and impairs insulin secretion in rat islets and clonal beta cells
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- Contribution to journal › Article
- 2016
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NIH working group report-using genomic information to guide weight management: From universal to precision treatment.
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- Contribution to journal › Scientific review
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A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes
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- Contribution to journal › Article
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A genome-wide mQTL analysis in human adipose tissue identifies genetic variants associated with DNA methylation, gene expression and metabolic traits
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- Contribution to journal › Article
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Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes
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- Contribution to journal › Article
- 2015
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Less pronounced response to exercise in healthy relatives to type 2 diabetics compared to controls.
(
- Contribution to journal › Article
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Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood.
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- Contribution to journal › Article
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Genome-wide analysis of DNA methylation in subjects with type 1 diabetes identifies epigenetic modifications associated with proliferative diabetic retinopathy.
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- Contribution to journal › Article
- 2014
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Sex differences in the genome-wide DNA methylation pattern and impact on gene expression, microRNA levels and insulin secretion in human pancreatic islets
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- Contribution to journal › Article
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A Central Role for GRB10 in Regulation of Islet Function in Man.
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- Contribution to journal › Article
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Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion.
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- Contribution to journal › Article
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Extensive changes in the transcriptional profile of human adipose tissue including genes involved in oxidative phosphorylation after a six months exercise intervention.
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- Contribution to journal › Article
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Altered DNA methylation and differential expression of genes influencing metabolism and inflammation in adipose tissue from subjects with type 2 diabetes.
(
- Contribution to journal › Article
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Genome-Wide Associations between Genetic and Epigenetic Variation Influence mRNA Expression and Insulin Secretion in Human Pancreatic Islets.
(
- Contribution to journal › Article
- 2013
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DNA methylation of the glucagon-like peptide 1 receptor (GLP1R) in human pancreatic islets.
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- Contribution to journal › Article
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A six months exercise intervention influences the genome-wide DNA methylation pattern in human adipose tissue.
(
- Contribution to journal › Article
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Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets.
(
- Contribution to journal › Article
- 2012
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First-Degree Relatives of Type 2 Diabetic Patients Have Reduced Expression of Genes Involved in Fatty Acid Metabolism in Skeletal Muscle.
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- Contribution to journal › Article
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Effects of short-term high-fat overfeeding on genome-wide DNA methylation in the skeletal muscle of healthy young men
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- Contribution to journal › Article
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A Single Nucleotide Polymorphism Associates With the Response of Muscle ATP Synthesis to Long-Term Exercise Training in Relatives of Type 2 Diabetic Humans
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- Contribution to journal › Article
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Increased DNA Methylation and Decreased Expression of PDX-1 in Pancreatic Islets from Patients with Type 2 Diabetes.
(
- Contribution to journal › Article
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Reduced insulin secretion correlates with decreased expression of exocytotic genes in pancreatic islets from patients with type 2 diabetes.
(
- Contribution to journal › Article
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Telomere length in blood and skeletal muscle in relation to measures of glycaemia and insulinaemia.
(
- Contribution to journal › Article
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Impact of an Exercise Intervention on DNA Methylation in Skeletal Muscle From First-Degree Relatives of Patients With Type 2 Diabetes.
2012) In Diabetes(
- Contribution to journal › Article
- 2011
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Two common genetic variants near nuclear encoded OXPHOS genes are associated with insulin secretion in vivo.
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- Contribution to journal › Article
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A common variant near the PRL gene is associated with increased adiposity in males
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- Contribution to journal › Article
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Maternal diet and aging alter the epigenetic control of a promoter-enhancer interaction at the Hnf4a gene in rat pancreatic islets
(
- Contribution to journal › Article
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The expression of myosin heavy chain (MHC) genes in human skeletal muscle is related to metabolic characteristics involved in the pathogenesis of type 2 diabetes.
(
- Contribution to journal › Article
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Mark
Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA(1c) levels in human pancreatic islets.
(
- Contribution to journal › Article
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Mark
Decreased expression of genes involved in oxidative phosphorylation in human pancreatic islets from patients with type 2 diabetes.
(
- Contribution to journal › Article
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A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes.
(
- Contribution to journal › Article
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Genetic variation in the GCKR gene is associated with non-alcoholic fatty liver disease in Chinese people
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- Contribution to journal › Article
- 2010
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A mRNA marker for glycolytic muscle fibres may be used to determine fibre type composition in human skeletal muscle
2010) 46th Annual Meeting of the European-Association-for-the- Study-of-Diabetes (EASD) In Diabetologia 53(Suppl. 1). p.705-705(
- Contribution to journal › Published meeting abstract
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Mark
Epigenetics and obesity: the devil is in the details
(
- Contribution to journal › Debate/Note/Editorial
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THE ROLE OF SNARE PROTEINS IN HUMAN INSULIN RESISTANCE
2010) 78th Congress of the European-Atherosclerosis-Society In Atherosclerosis Supplements 11(2). p.283-283(
- Contribution to journal › Published meeting abstract
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Mark
Investigation of Type 2 Diabetes Risk Alleles Support CDKN2A/B, CDKAL1, and TCF7L2 As Susceptibility Genes in a Han Chinese Cohort
(
- Contribution to journal › Article
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Mark
The SNARE Protein SNAP23 and the SNARE-Interacting Protein Munc18c in Human Skeletal Muscle Are Implicated in Insulin Resistance/Type 2 Diabetes
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- Contribution to journal › Article
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Mark
A lipotoxicity model in the INS-1 832/13 beta cell line and the epigenetic alterations induced by it
2010) 46th Annual Meeting of the European-Association-for-the- Study-of-Diabetes (EASD) In Diabetologia 53(Suppl. 1). p.348-348(
- Contribution to journal › Published meeting abstract
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Mark
Resistance to exercise-induced changes in the global DNA methylation pattern of skeletal muscle in individuals with a family history of type 2 diabetes
2010) 46th Annual Meeting of the European-Association-for-the- Study-of-Diabetes (EASD) In Diabetologia 53(Suppl. 1). p.312-312(
- Contribution to journal › Published meeting abstract
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Mark
Nesfatin-1 stimulates insulin secretion, inhibits glucagon secretion and is expressed in human and rodent beta cells
2010) 46th Annual Meeting of the European-Association-for-the- Study-of-Diabetes (EASD) In Diabetologia 53(Suppl. 1). p.548-548(
- Contribution to journal › Published meeting abstract
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Mark
Elevated Serum Chemokine CXC Ligand 5 Levels Are Associated with Hypercholesterolemia But Not a Worsening of Insulin Resistance in Chinese People.
(
- Contribution to journal › Article
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Mark
The Association of Mitochondrial Content with Prevalent and Incident Type 2 Diabetes.
(
- Contribution to journal › Article
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Deoxyribonucleic Acid Methylation and Gene Expression of PPARGC1A in Human Muscle Is Influenced by High-Fat Overfeeding in a Birth-Weight-Dependent Manner.
(
- Contribution to journal › Article
- 2009
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Mark
Effects of six months of moderate resistance-versus endurance-training on muscle ATP synthesis in first-degree relatives of patients with type 2 diabetes
2009) 45th Annual Meeting of the European-Association-for-the-Study-of-Diabetes In Diabetologia 52(Suppl 1). p.687-687(
- Contribution to journal › Published meeting abstract
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Mark
Regulation and Function of FTO mRNA Expression in Human Skeletal Muscle and Subcutaneous Adipose Tissue
(
- Contribution to journal › Article
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Mark
Epigenetics: A Molecular Link Between Environmental Factors and Type 2 Diabetes
(
- Contribution to journal › Scientific review
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Mark
Prolactin Suppresses Malonyl-CoA Concentration in Human Adipose Tissue
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- Contribution to journal › Article
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Mark
Mitochondrial dysfunction in pancreatic beta-cells in Type 2 Diabetes.
(
- Contribution to journal › Article
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Mark
Calpain-10 expression is elevated in pancreatic islets from patients with type 2 diabetes.
(
- Contribution to journal › Article
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Mark
Tight coupling between glucose and mitochondrial metabolism in clonal beta-cells is required for robust insulin secretion.
(
- Contribution to journal › Article
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A common variant in MTNR1B, encoding melatonin receptor 1B, is associated with type 2 diabetes and fasting plasma glucose in Han Chinese individuals.
(
- Contribution to journal › Article
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Mark
Genetic variation in ATP5O is associated with skeletal muscle ATP50 mRNA expression and glucose uptake in young twins.
(
- Contribution to journal › Article
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Mark
Disruption of TFB1M impairs insulin secretion in beta cells
2009) 45th Annual Meeting of the European-Association-for-the-Study-of-Diabetes In Diabetologia 52(Suppl 1). p.116-116(
- Contribution to journal › Published meeting abstract
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Mark
Short-Term Exercise Training Does Not Stimulate Skeletal Muscle ATP Synthesis in Relatives of Humans With Type 2 Diabetes
(
- Contribution to journal › Article
- 2008
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Mark
PGC-1 alpha and PGC-1 beta are related to markers for fibre type composition in human skeletal muscle
2008) 44th EASD Annual Meeting of the European Association for the Study of Diabetes In Diabetologia 51(S1). p.130-130(
- Contribution to journal › Published meeting abstract
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Mark
Genetic variation in ATP5O is associated with mRNA expression in human skeletal muscle and in vivo glucose uptake
2008) 44th EASD Annual Meeting of the European Association for the Study of Diabetes In Diabetologia 51(Supplement 1). p.132-132(
- Contribution to journal › Published meeting abstract
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Mark
Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion.
(
- Contribution to journal › Article
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Molecular correlates for maximal oxygen uptake (VO2max) and type 1 fibers.
(
- Contribution to journal › Article
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Age influences DNA methylation and gene expression of COX7A1 in human skeletal muscle.
(
- Contribution to journal › Article
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Differences in prolactin receptor (PRLR) in mouse and human fallopian tubes: Evidence for multiple regulatory mechanisms controlling PRLR isoform expression in mice
(
- Contribution to journal › Article
- 2007
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Mark
Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes.
(
- Contribution to journal › Article
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Mark
Regulation of skeletal muscle PPAR delta mRNA expression in twins
(
- Contribution to journal › Article
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Relationships of plasma adiponectin level and adiponectin receptors 1 and 2 gene expression to insulin sensitivity and glucose and fat metabolism in monozygotic and dizygotic twins.
(
- Contribution to journal › Article
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Mark
Genetic and epigenetic factors are associated with expression of respiratory chain component NDUFB6 in human skeletal muscle
(
- Contribution to journal › Article
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Mark
Impact of the peroxisome proliferator activated receptor-gamma coactivator-1 beta (PGC-1 beta) Ala203Pro polymorphism on in vivo metabolism, PGC-1 beta expression and fibre type composition in human skeletal muscle
(
- Contribution to journal › Article
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Mark
Enhanced mitochondrial metabolism may account for the adaptation to insulin resistance in islets from C57BL/6J mice fed a high-fat diet.
(
- Contribution to journal › Article
- 2006
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Mark
Developmental and hormonal regulation of progesterone receptor A-form expression in female mouse lung in vivo: interaction with glucocorticoid receptors
(
- Contribution to journal › Article
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Mark
Genetic and nongenetic determinants of skeletal muscle glucose transporter 4 messenger ribonucleic acid levels and insulin action in twins
(
- Contribution to journal › Article
- 2005
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Mark
Epigenetic differences arise during the lifetime of monozygotic twins
(
- Contribution to journal › Article
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Mark
Prolactin and growth hormone regulate adiponectin secretion and receptor expression in adipose tissue
(
- Contribution to journal › Article
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Mark
Genetic and Nongenetic Regulation of CAPN10 mRNA Expression in Skeletal Muscle.
(
- Contribution to journal › Article
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Mark
Transcriptome and proteome analysis of soleus muscle of hormone-sensitive lipase-null mice
(
- Contribution to journal › Article
- 2004
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Mark
Multiple environmental and genetic factors influence skeletal muscle PGC-1alpha and PGC-1beta gene expression in twins.
(
- Contribution to journal › Article
- 2003
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Mark
Identification of functional prolactin (PRL) receptor gene expression: PRL inhibits lipoprotein lipase activity in human white adipose tissue
(
- Contribution to journal › Article