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- 2024
-
Mark
AlphaML : A clear, legible, explainable, transparent, and elucidative binary classification platform for tabular data
(
- Contribution to journal › Article
-
Mark
Discovery of a small molecule that inhibits Bcl-3-mediated cyclin D1 expression in melanoma cells
(
- Contribution to journal › Article
-
Mark
DDR1/2 enhance KIT activation and imatinib resistance of primary and secondary KIT mutants in gastrointestinal stromal tumors
(
- Contribution to journal › Article
- 2023
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Mark
Understanding the Role of Activation Loop Mutants in Drug Efficacy for FLT3-ITD
(
- Contribution to journal › Article
-
Mark
PLK1 as a cooperating partner for BCL2-mediated antiapoptotic program in leukemia
(
- Contribution to journal › Article
-
Mark
Venetoclax-Resistant T-ALL Cells Display Distinct Cancer Stem Cell Signatures and Enrichment of Cytokine Signaling
(
- Contribution to journal › Article
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Mark
A deep tabular data learning model predicting cisplatin sensitivity identifies BCL2L1 dependency in cancer
(
- Contribution to journal › Article
-
Mark
A Receptor Tyrosine Kinase Inhibitor Sensitivity Prediction Model Identifies AXL Dependency in Leukemia
(
- Contribution to journal › Article
-
Mark
AI-Driven Drug Response Prediction for Personalized Cancer Medicine
(
- Chapter in Book/Report/Conference proceeding › Book chapter
- 2022
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Mark
Phosphorylation-Dependent Regulation of WNT/Beta-Catenin Signaling
(
- Contribution to journal › Scientific review
-
Mark
Phosphoproteomics of primary AML patient samples reveals rationale for AKT combination therapy and p53 context to overcome selinexor resistance
(
- Contribution to journal › Article
- 2021
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Mark
Machine learning in the prediction of cancer therapy
(
- Contribution to journal › Scientific review
-
Mark
The Aurora kinase/β-catenin axis contributes to dexamethasone resistance in leukemia
(
- Contribution to journal › Article
-
Mark
T cell receptor (TCR) signaling in health and disease
(
- Contribution to journal › Scientific review
- 2020
-
Mark
Mechanisms of anticancer therapy resistance : the role of cancer stem cells
(
- Contribution to journal › Debate/Note/Editorial
- 2019
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Mark
FMS-like Tyrosine Kinase 3/FLT3 : From Basic Science to Clinical Implications
(
- Contribution to journal › Article
-
Mark
The role of SRC family kinases in FLT3 signaling
(
- Contribution to journal › Scientific review
-
Mark
Glucocorticoid-resistant B cell acute lymphoblastic leukemia displays receptor tyrosine kinase activation
(
- Contribution to journal › Article
-
Mark
The ALK inhibitor AZD3463 effectively inhibits growth of sorafenib-resistant acute myeloid leukemia
(
- Contribution to journal › Letter
-
Mark
Metallopeptidase inhibitor 1 (TIMP-1) promotes receptor tyrosine kinase c-Kit signaling in colorectal cancer
(
- Contribution to journal › Article
- 2018
-
Mark
SRC-like adaptor protein 2 (SLAP2) is a negative regulator of KIT-D816V-mediated oncogenic transformation
(
- Contribution to journal › Article
-
Mark
Acute leukemia cells resistant to PI3K/mTOR inhibition display upregulation of P2RY14 expression
(
- Contribution to journal › Letter
-
Mark
Bruton’s tyrosine kinase potentiates ALK signaling and serves as a potential therapeutic target of neuroblastoma
(
- Contribution to journal › Article
-
Mark
De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia
(
- Contribution to journal › Article
- 2017
-
Mark
BEX3
2017) p.1-4(
- Chapter in Book/Report/Conference proceeding › Entry for encyclopaedia/dictionary
-
Mark
Tyrosine 842 in the activation loop is required for full transformation by the oncogenic mutant FLT3-ITD
(
- Contribution to journal › Article
-
Mark
The dual specificity PI3K/mTOR inhibitor PKI-587 displays efficacy against T-cell acute lymphoblastic leukemia (T-ALL)
(
- Contribution to journal › Article
-
Mark
ABL2 suppresses FLT3-ITD-induced cell proliferation through negative regulation of AKT signaling
(
- Contribution to journal › Article
-
Mark
The Src family kinase LCK cooperates with oncogenic FLT3/ITD in cellular transformation
(
- Contribution to journal › Article
-
Mark
Efficacy of the CDK inhibitor dinaciclib in vitro and in vivo in T-cell acute lymphoblastic leukemia
(
- Contribution to journal › Article
-
Mark
KITD816V induces SRC-mediated tyrosine phosphorylation of MITF and altered transcription program in melanoma
(
- Contribution to journal › Article
-
Mark
T-cell acute lymphoblastic leukemia cells display activation of different survival pathways
(
- Contribution to journal › Article
- 2016
-
Mark
HIF2α contributes to antiestrogen resistance via positive bilateral crosstalk with EGFR in breast cancer cells.
(
- Contribution to journal › Article
-
Mark
Expression of GADS enhances FLT3-induced mitogenic signaling.
(
- Contribution to journal › Article
-
Mark
FYN expression potentiates FLT3-ITD induced STAT5 signaling in acute myeloid leukemia.
(
- Contribution to journal › Article
-
Mark
Src-Like Adapter Protein (SLAP)
2016) p.1-4(
- Chapter in Book/Report/Conference proceeding › Entry for encyclopaedia/dictionary
-
Mark
Germline mutations of KIT in gastrointestinal stromal tumor (GIST) and mastocytosis
(
- Contribution to journal › Scientific review
-
Mark
GRB10
2016) p.1-4(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
FMS-Like Tyrosine Kinase-3
2016) p.1-4(
- Chapter in Book/Report/Conference proceeding › Entry for encyclopaedia/dictionary
-
Mark
Kit
2016) p.1-5(
- Chapter in Book/Report/Conference proceeding › Entry for encyclopaedia/dictionary
-
Mark
Src-like adaptor protein 2 (SLAP2) binds to and inhibits FLT3 signaling
(
- Contribution to journal › Article
-
Mark
Aberrant activation of the PI3K/mTOR pathway promotes resistance to sorafenib in AML
(
- Contribution to journal › Article
-
Mark
Src-Like Adapter Protein 2 (SLAP2)
(
- Chapter in Book/Report/Conference proceeding › Entry for encyclopaedia/dictionary
- 2015
-
Mark
Brain-Expressed X-linked (BEX) proteins in human cancers.
(
- Contribution to journal › Scientific review
-
Mark
SOCS6 (suppressor of cytokine signaling 6)
(
- Contribution to journal › Scientific review
-
Mark
The Phosphatases STS1 and STS2 Regulate Hematopoietic Stem and Progenitor Cell Fitness.
(
- Contribution to journal › Article
-
Mark
BEX1 acts as a tumor suppressor in acute myeloid leukemia.
(
- Contribution to journal › Article
-
Mark
PI3 kinase is indispensable for oncogenic transformation by the V560D mutant of c-Kit in a kinase-independent manner.
(
- Contribution to journal › Article
-
Mark
Role of SRC-like adaptor protein (SLAP) in immune and malignant cell signaling.
(
- Contribution to journal › Scientific review
-
Mark
The role of HOXB2 and HOXB3 in acute myeloid leukemia.
(
- Contribution to journal › Article
-
Mark
The activation loop tyrosine 823 is essential for the transforming capacity of the c-Kit oncogenic mutant D816V.
(
- Contribution to journal › Article
-
Mark
Bone Marrow Transplants
2015) p.129-132(
- Chapter in Book/Report/Conference proceeding › Entry for encyclopaedia/dictionary
-
Mark
Drug Testing and Drug Development in Cell Culture
2015) p.363-366(
- Chapter in Book/Report/Conference proceeding › Entry for encyclopaedia/dictionary
-
Mark
Fluorescence-Activated Cell Sorting
2015) p.418-420(
- Chapter in Book/Report/Conference proceeding › Entry for encyclopaedia/dictionary
- 2014
-
Mark
SOCS6 is a selective suppressor of receptor tyrosine kinase signaling
(
- Contribution to journal › Scientific review
-
Mark
Keratin 19 expression correlates with poor prognosis in breast cancer
(
- Contribution to journal › Article
-
Mark
Grb10 is a dual regulator of receptor tyrosine kinase signaling
(
- Contribution to journal › Scientific review
-
Mark
SYK Is a Critical Regulator of FLT3 in Acute Myeloid Leukemia.
(
- Contribution to journal › Article
-
Mark
SOCS proteins in regulation of receptor tyrosine kinase signaling.
(
- Contribution to journal › Scientific review
-
Mark
Src-Like Adaptor Protein (SLAP) differentially regulates normal and oncogenic c-Kit signaling
(
- Contribution to journal › Article
-
Mark
The PI3-kinase isoform p110δ is essential for cell transformation induced by the D816V mutant of c-Kit in a lipid-kinase-independent manner.
(
- Contribution to journal › Article
- 2013
-
Mark
The basic helix-loop-helix (bHLH) proteins in breast cancer progression
(
- Contribution to journal › Letter
-
Mark
Selective mutation in ATP-binding site reduces affinity of drug to the kinase: a possible mechanism of chemo-resistance
(
- Contribution to journal › Letter
-
Mark
Deregulation of protein phosphatase expression in acute myeloid leukemia
(
- Contribution to journal › Article
-
Mark
FLT3 mutations in patients with childhood acute lymphoblastic leukemia (ALL)
(
- Contribution to journal › Letter
-
Mark
Protein kinase C expression is deregulated in chronic lymphocytic leukemia
(
- Contribution to journal › Letter
-
Mark
FLT3 signals via the adapter protein Grb10 and overexpression of Grb10 leads to aberrant cell proliferation in acute myeloid leukemia.
(
- Contribution to journal › Article
-
Mark
Phosphorylation of the activation loop tyrosine 823 in c-Kit is crucial for cell survival and proliferation.
(
- Contribution to journal › Article
-
Mark
The tyrosine kinase CSK associates with FLT3 and c-Kit receptors and regulates downstream signaling.
(
- Contribution to journal › Article
-
Mark
Suppressor of cytokine signaling 2 (SOCS2) associates with FLT3 and negatively regulates downstream signaling.
(
- Contribution to journal › Article
-
Mark
Protein kinase C (PKC) as a drug target in chronic lymphocytic leukemia.
(
- Contribution to journal › Scientific review
-
Mark
The presence or absence of IL-3 during long-term culture of Flt3-ITD and c-Kit-D816V expressing Ba/F3 cells influences signaling outcome.
(
- Contribution to journal › Letter
- 2012
-
Mark
Src-Like Adaptor Protein (SLAP) Binds to the Receptor Tyrosine Kinase Flt3 and Modulates Receptor Stability and Downstream Signaling.
(
- Contribution to journal › Article
-
Mark
Adaptor protein Lnk binds to and inhibits normal and leukemic FLT3
(
- Contribution to journal › Article
-
Mark
Suppressor Of cytokine signaling 6 (SOCS6) negatively regulates Flt3 signal transduction through direct binding to phosphorylated Tyr 591 and Tyr 919 of Flt3.
(
- Contribution to journal › Article
- 2011
-
Mark
Maximum likelihood analysis of mammalian p53 indicates the presence of positively selected sites and higher tumorigenic mutations in purifying sites
(
- Contribution to journal › Article
-
Mark
The mechanism of protein kinase C regulation
(
- Contribution to journal › Scientific review
-
Mark
Comparative analysis of human and bovine protein kinases reveals unique relationship and functional diversity
(
- Contribution to journal › Article
-
Mark
Comparative Studies on Human and Rat Basic Helix-loop-helix Proteins
(
- Contribution to journal › Article
- 2010
-
Mark
Visualization of the melanosome transfer-inhibition in a mouse epidermal cell co-culture model.
(
- Contribution to journal › Article
- 2009
-
Mark
Subcellular Localization of Diacylglycerol-responsive Protein Kinase C Isoforms in HeLa Cells
(
- Contribution to journal › Article
- 2008
-
Mark
Bioinformatic prediction and analysis of eukaryotic protein kinases in the rat genome.
(
- Contribution to journal › Article
-
Mark
Celecoxib-induced growth inhibition in SW480 colon cancer cells is associated with activation of protein kinase G
(
- Contribution to journal › Article
-
Mark
Role of Regulatory Domain Mutants of PKC Isoforms in c-fos Induction
(
- Contribution to journal › Article
-
Mark
Induction of the nuclear proto-oncogene c-fos by the phorbol ester TPA and v-H-Ras.
(
- Contribution to journal › Article
- 2007
-
Mark
Isoform-specific translocation of PKC isoforms in NIH3T3 cells by TPA.
(
- Contribution to journal › Article