Division of Molecular Medicine and Gene Therapy
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- 2018
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Mark
The Role of Hepatic Leukemia Factor in Hematopoiesis
2018)(
- Thesis › Doctoral thesis (compilation)
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Mark
Targeting NSG Mice Engrafting Cells with a Clinically Applicable Lentiviral Vector Corrects Osteoclasts in Infantile Malignant Osteopetrosis
(
- Contribution to journal › Article
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Mark
Interleukin 4 induces apoptosis of acute myeloid leukemia cells in a Stat6 dependent manner
(
- Contribution to journal › Article
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Mark
In vitro tumorigenic assay : colony forming assay for cancer stem cells
(
- Chapter in Book/Report/Conference proceeding › Book chapter
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Mark
Ihor R. Lemischka (1953-2017)
(
- Contribution to journal › Debate/Note/Editorial
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Mark
Small Molecule Screens Identify CDK8-Inhibitors As Candidate Diamond-Blackfan Anemia Drugs
(
- Contribution to journal › Published meeting abstract
- 2017
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Mark
The impact of socio-economic factors on treatment choice and mortality in chronic myeloid leukaemia
(
- Contribution to journal › Article
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Mark
Single-cell molecular analysis defines therapy response and immunophenotype of stem cell subpopulations in CML
(
- Contribution to journal › Article
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Mark
Direct lineage reprogramming : a useful addition to the blood cell research toolbox
(
- Contribution to journal › Debate/Note/Editorial
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Mark
Forced expression of human macrophage colony-stimulating factor in CD34+ cells promotes monocyte differentiation in vitro and in vivo but blunts osteoclastogenesis in vitro
2017) In European Journal of Haematology(
- Contribution to journal › Article
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Mark
Induction of the 5S RNP–Mdm2–p53 ribosomal stress pathway delays the initiation but fails to eradicate established murine acute myeloid leukemia
(
- Contribution to journal › Article
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Mark
Management and monitoring recommendations for the use of eliglustat in adults with type 1 Gaucher disease in Europe
(
- Contribution to journal › Scientific review
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Mark
Advanced phase chronic myeloid leukaemia (CML) in the tyrosine kinase inhibitor era - a report from the Swedish CML register
(
- Contribution to journal › Article
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Mark
Reactive Oxygen Species Impair the Function of CD90+ Hematopoietic Progenitors Generated from Human Pluripotent Stem Cells
(
- Contribution to journal › Article
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Mark
Roscoe Owen Brady, MD : Remembrances of co-investigators and colleagues
(
- Contribution to journal › Article
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Mark
Increased proportion of mature NK cells is associated with successful imatinib discontinuation in chronic myeloid leukemia
(
- Contribution to journal › Article
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Mark
Agonistic targeting of TLR1/TLR2 induces p38 MAPK-dependent apoptosis and NFκB-dependent differentiation of AML cells
(
- Contribution to journal › Article
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Mark
Erythroid Culture Based on Differentiation of Progenitor Cells from Leftover Buffy Coats Produced in the Reveos Automated Blood Processing System
2017) 27th Regional Congress of the International Society of Blood Transfusion, ISBT 2017 In Vox Sanguinis 112(supp 1). p.288-288(
- Contribution to journal › Published meeting abstract
-
Mark
Critical Modulation of Hematopoietic Lineage Fate by Hepatic Leukemia Factor
(
- Contribution to journal › Article
-
Mark
Barcodes show family trees in ALL
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Kronisk myeloisk leukemi : förebild för målstyrd terapi - Revolutionerande överlevnadsvinster med definitiv bot i sikte och kraftigt förbättrad hälsoekonomi
(
- Contribution to journal › Article
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Mark
Hepatic Leukemia Factor Maintains Quiescence of Hematopoietic Stem Cells and Protects the Stem Cell Pool during Regeneration
(
- Contribution to journal › Article
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Mark
The stem cell regulator PEDF is dispensable for maintenance and function of hematopoietic stem cells
(
- Contribution to journal › Article
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Mark
Term amniotic fluid : An unexploited reserve of mesenchymal stromal cells for reprogramming and potential cell therapy applications
(
- Contribution to journal › Article
-
Mark
Technical considerations for the use of CRISPR/Cas9 in hematology research
2017) In Experimental Hematology(
- Contribution to journal › Article
-
Mark
Single-Cell Analysis Identifies Distinct Stages of Human Endothelial-to-Hematopoietic Transition
(
- Contribution to journal › Article
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Mark
Cytohesin 1 regulates homing and engraftment of human hematopoietic stem and progenitor cells
(
- Contribution to journal › Article
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Mark
Lentiviral Vectors with Cellular Promoters Correct Anemia and Lethal Bone Marrow Failure in a Mouse Model for Diamond-Blackfan Anemia
(
- Contribution to journal › Article
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Mark
Signaling via Smad2 and Smad3 is dispensable for adult murine hematopoietic stem cell function in vivo
2017) In Experimental Hematology(
- Contribution to journal › Article
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Mark
Modelling Human Developmental Hematopoiesis. Towards in vitro Generation of Human Hematopoietic Stem Cells
2017)(
- Thesis › Doctoral thesis (compilation)
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Mark
The Effects of Genetic and Epigenetic Variation on Human Pluripotent Stem Cell Differentiation
2017)(
- Thesis › Doctoral thesis (compilation)
-
Mark
No increased prevalence of malignancies among first-degree relatives of 800 patients with chronic myeloid leukemia : A population-based study in Sweden
(
- Contribution to journal › Letter
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Mark
Development of novel therapies for Diamond-Blackfan Anemia
2017)(
- Thesis › Doctoral thesis (compilation)
-
Mark
Direct conversion of human fibroblasts to functional excitatory cortical neurons integrating into human neural networks
(
- Contribution to journal › Article
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Mark
Kronisk myeloisk leukemi : Förebild för målstyrd terapi
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Forward RNAi screens in human hematopoietic stem cells
(
- Chapter in Book/Report/Conference proceeding › Book chapter
- 2016
-
Mark
A network including TGFβ/Smad4, Gata2 and p57 regulates proliferation of mouse hematopoietic progenitor cells.
(
- Contribution to journal › Article
-
Mark
Small molecule screen identifies differentiation-promoting compounds targeting genetically diverse acute myeloid leukaemia.
(
- Contribution to journal › Article
-
Mark
Bile Acids Protect Expanding Hematopoietic Stem Cells from Unfolded Protein Stress in Fetal Liver.
(
- Contribution to journal › Article
-
Mark
Population-based assessment of chronic myeloid leukemia in Sweden: striking increase in survival and prevalence.
(
- Contribution to journal › Article
-
Mark
Glucosylated cholesterol in mammalian cells and tissues: formation and degradation by multiple cellular β-glucosidases.
(
- Contribution to journal › Article
-
Mark
Genetic Variability Overrides the Impact of Parental Cell Type and Determines iPSC Differentiation Potential.
(
- Contribution to journal › Article
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Mark
Direct Conversion of Fibroblasts to Megakaryocyte Progenitors
(
- Contribution to journal › Article
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Mark
Cyclic AMP Signaling through Epac Axis Modulates Human Hemogenic Endothelium and Enhances Hematopoietic Cell Generation
(
- Contribution to journal › Article
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Mark
Defining the Minimal Factors Required for Erythropoiesis through Direct Lineage Conversion
(
- Contribution to journal › Article
-
Mark
The european hematology association roadmap for european hematology research : A consensus document
(
- Contribution to journal › Article
-
Mark
Regulation and Function of Lentiviral Vector-Mediated TCIRG1 Expression in Osteoclasts from Patients with Infantile Malignant Osteopetrosis : Implications for Gene Therapy
(
- Contribution to journal › Article
-
Mark
Endoplasmic reticulum stress regulation in hematopoietic stem cells
(
- Contribution to journal › Article
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Mark
Cardiovascular events associated with use of tyrosine kinase inhibitors in chronic myeloid leukemia
(
- Contribution to journal › Article
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Mark
BCAT1, a key prognostic predictor of hepatocellular carcinoma, promotes cell proliferation and induces chemoresistance to cisplatin
(
- Contribution to journal › Article
-
Mark
Pathways that govern hematopoietic stem cell fate
2016)(
- Thesis › Doctoral thesis (compilation)
-
Mark
Plasma proteomics in CML patients before and after initiation of tyrosine kinase inhibitor therapy reveals induced Th1 immunity and loss of angiogenic stimuli
(
- Contribution to journal › Article
-
Mark
Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitors
(
- Contribution to journal › Article
-
Mark
Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma
(
- Contribution to journal › Article
-
Mark
Macrophage colony-stimulating factor receptor marks and regulates a fetal myeloid-primed B-cell progenitor in mice
(
- Contribution to journal › Article
-
Mark
Mutation of the key residue for extraribosomal function of ribosomal protein S19 cause increased grooming behaviors in mice
(
- Contribution to journal › Article
-
Mark
Potential Pitfalls of the Mx1-Cre System : Implications for Experimental Modeling of Normal and Malignant Hematopoiesis
(
- Contribution to journal › Article
-
Mark
The stem cell niche finds its true north
(
- Contribution to journal › Scientific review
-
Mark
IL1RAP antibodies block IL-1-induced expansion of candidate CML stem cells and mediate cell killing in xenograft models
(
- Contribution to journal › Article
-
Mark
G protein-coupled Receptor 30 (GPR30) PDZ-dependently and Constitutively Increases ERK1/2 Signaling Through Calcineurin and Kinase Suppressor of Ras 2 (KSR2)
(
- Contribution to journal › Published meeting abstract
-
Mark
In vivo CYP3A activity and pharmacokinetics of imatinib in relation to therapeutic outcome in chronic myeloid leukemia patients.
(
- Contribution to journal › Article
-
Mark
Leukemic stem cell quantification in newly diagnosed chronic myeloid leukemia patients predicts response to nilotinib therapy
(
- Contribution to journal › Article
-
Mark
Genome-wide RNAi Screen Identifies Cohesin Genes as Modifiers of Renewal and Differentiation in Human HSCs
(
- Contribution to journal › Article
-
Mark
The putative tumor suppressor gene EphA7 is a novel BMI-1 target
(
- Contribution to journal › Article
-
Mark
A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional network
(
- Contribution to journal › Article
-
Mark
Expansion and Biased Commitment of Hematopoietic Stem Cells Towards Erythroid Cells upon Acute Anemia Induction
(
- Contribution to journal › Published meeting abstract
- 2015
-
Mark
Cell and gene therapy for blood disorders. Modeling of novel treatment strategies for Gaucher type 1 disease and Diamond-Blackfan anemia in mice.
(
- Thesis › Doctoral thesis (compilation)
-
Mark
Protein receptor-independent plasma membrane remodeling by HAMLET: a tumoricidal protein-lipid complex.
(
- Contribution to journal › Article
-
Mark
Monitoring Low Molecular Weight Heparins at Therapeutic Levels: Dose-Responses of, and Correlations and Differences between aPTT, Anti-Factor Xa and Thrombin Generation Assays.
(
- Contribution to journal › Article
-
Mark
Towards Generation of Human Hematopoietic Stem Cells from Pluripotent Stem Cells.
(
- Thesis › Doctoral thesis (compilation)
-
Mark
TGIF1 is a negative regulator of MLL-rearranged acute myeloid leukemia.
(
- Contribution to journal › Article
-
Mark
Dasatinib induces fast and deep responses in newly diagnosed chronic myeloid leukaemia patients in chronic phase: clinical results from a randomised phase-2 study (NordCML006)
(
- Contribution to journal › Article
-
Mark
Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond-Blackfan anaemia.
(
- Contribution to journal › Article
-
Mark
Coexpression of hyperactivated AKT1 with additional genes activated in leukemia drives hematopoietic progenitor cells to cell cycle block and apoptosis.
(
- Contribution to journal › Article
-
Mark
Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia.
(
- Contribution to journal › Article
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Mark
The Tyrosine Kinase Inhibitors Imatinib and Dasatinib Reduce Myeloid Suppressor Cells and Release Effector Lymphocyte Responses
(
- Contribution to journal › Article
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Mark
Retinoic Acid regulates hematopoietic development from human pluripotent stem cells.
(
- Contribution to journal › Article
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Mark
Integrin Based Isolation Enables Purification of Murine Lineage Committed Cardiomyocytes
(
- Contribution to journal › Article
-
Mark
Inhibition of UDP-glucosylceramide synthase in mice prevents Gaucher disease-associated B-cell malignancy
(
- Contribution to journal › Article
-
Mark
The activation loop tyrosine 823 is essential for the transforming capacity of the c-Kit oncogenic mutant D816V.
(
- Contribution to journal › Article
-
Mark
TGF-β signaling in the control of hematopoietic stem cells.
(
- Contribution to journal › Article
-
Mark
Disruption of the 5S RNP-Mdm2 interaction significantly improves the erythroid defect in a mouse model for Diamond-Blackfan anemia.
(
- Contribution to journal › Article
-
Mark
Jarid2 regulates hematopoietic stem cell function by acting with polycomb repressive complex 2.
(
- Contribution to journal › Article
-
Mark
Lentiviral gene therapy using cellular promoters cures type 1 Gaucher disease in mice.
(
- Contribution to journal › Article
-
Mark
ERG promotes the maintenance of hematopoietic stem cells by restricting their differentiation.
(
- Contribution to journal › Article
-
Mark
Two new routes to make blood: Hematopoietic specification from pluripotent cell lines vs. reprogramming of somatic cells.
(
- Contribution to journal › Article
-
Mark
Second malignancies following treatment of chronic myeloid leukaemia in the tyrosine kinase inhibitor era
(
- Contribution to journal › Article
-
Mark
Loss of HIF-1α accelerates murine FLT-3ITD-induced myeloproliferative neoplasia.
(
- Contribution to journal › Article
-
Mark
Case-report: EBV driven lymphoproliferative disorder associated with Ruxolitinib.
(
- Contribution to journal › Article
-
Mark
Young woman with mild bone marrow dysplasia, GATA2 and ASXL1 mutation treated with allogeneic hematopoietic stem cell transplantation.
(
- Contribution to journal › Article
- 2014
-
Mark
Development of Novel Models for Studying Osteoclasts
(
- Thesis › Doctoral thesis (compilation)
-
Mark
Modeling chronic myeloid leukemia in immunodeficient mice reveals expansion of aberrant mast cells and accumulation of pre-B cells.
(
- Contribution to journal › Article
-
Mark
Sortilin expression is essential for pro-nerve growth factor-induced apoptosis of rat vascular smooth muscle cells.
(
- Contribution to journal › Article
-
Mark
A Comparison of Osteoclast-Rich and Osteoclast-Poor Osteopetrosis in Adult Mice Sheds Light on the Role of the Osteoclast in Coupling Bone Resorption and Bone Formation
(
- Contribution to journal › Article
-
Mark
A Central Role for GRB10 in Regulation of Islet Function in Man.
(
- Contribution to journal › Article
-
Mark
RNA interference screening to detect targetable molecules in hematopoietic stem cells.
(
- Contribution to journal › Scientific review
-
Mark
Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism.
(
- Contribution to journal › Article
-
Mark
Optogenetic control of insulin secretion in intact pancreatic islets with β-cell-specific expression of Channelrhodopsin-2.
(
- Contribution to journal › Article
-
Mark
The nuclear localization of γ-tubulin is regulated by SadB-mediated phosphorylation.
(
- Contribution to journal › Article
-
Mark
HIF-1α can act as a tumor suppressor gene in murine Acute Myeloid Leukemia.
(
- Contribution to journal › Article