Targeted therapies in leukemia

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2025
Mark Aberrant expression of SLAMF6 constitutes a targetable immune escape mechanism in acute myeloid leukemia
Sandén, Carl ^LU ; Landberg, Niklas ^LU ; Peña-Martínez, Pablo ^LU ; Thorsson, Hanna ^LU ; Daga, Shruti ^LU ; Puente-Moncada, Noelia ^LU ; Rodriguez-Zabala, Maria ^LU ; von Palffy, Sofia ^LU ; Rissler, Marianne ^LU and Lazarevic, Vladimir ^LU , et al. (2025) In Nature Cancer 6(11). p.1821-1838
- Contribution to journal › Article
Mark The AML cellular state space unveils NPM1 immune evasion subtypes with distinct clinical outcomes
Lilljebjörn, Henrik ^LU ; Peña-Martínez, Pablo ^LU ; Thorsson, Hanna ^LU ; Henningsson, Rasmus ^LU ; Rissler, Marianne ^LU ; Landberg, Niklas ^LU ; Puente-Moncada, Noelia ^LU ; von Palffy, Sofia ^LU ; Rissler, Vendela ^LU and Stanek, Petr ^LU , et al. (2025) In Nature Communications 16. p.1-16
- Contribution to journal › Article
2024
Mark In-depth proteomic analysis and structural modelling of protein-protein interactions identify known and novel molecular binding partners for EMP3 in erythroid cells
Alattar, A G ^LU ; Ghosh, S ^LU ; Chouhan, B ^LU ; Pimkova, K ^LU ; Atkinson, G ^LU ; Flygare, J ^LU ; Hansson, J ^LU ; Storry, J ^LU and Olsson, Martin L ^LU (2024) In Vox Sanguinis 119(S1).
- Contribution to journal › Published meeting abstract
Mark Single-cell genomics details the maturation block in BCP-ALL and identifies therapeutic vulnerabilities in DUX4-r cases
Thorsson, Hanna ^LU ; Henningsson, Rasmus ^LU ; Puente-Moncada, Noelia ^LU ; Peña-Martínez, Pablo ^LU ; Sjöström, Ludvig ^LU ; Ågerstam, Helena ^LU ; Sandén, Carl ^LU ; Rissler, Marianne ^LU ; Castor, Anders ^LU and Marquart, Hanne , et al. (2024) In Blood 144(13). p.1399-1411
- Contribution to journal › Article
Mark Blocking IL1RAP on cancer-associated fibroblasts in pancreatic ductal adenocarcinoma suppresses IL-1-induced neutrophil recruitment
Hansen, Nils ^LU ; Peña-Martínez, Pablo ^LU ; Skoog, Petter ; Reinbach, Katrin ^LU ; Hansen, Finja C. ^LU ; Faria, Susanne Larsson ; Grönberg, Caitríona ; Abdilleh, Kawther ; Magnusson, Susanne and Von Wachenfeldt, Karin , et al. (2024) In Journal for ImmunoTherapy of Cancer 12(12).
- Contribution to journal › Article
Mark Apolipoprotein A-I priming via SR-BI and ABCA1 receptor binding upregulates mitochondrial metabolism to promote insulin secretion in INS-1E cells
Lyons, Claire L. ^LU ; Cowan, Elaine ^LU ; Nilsson, Oktawia ^LU ; Mohar, Manca ; Peña-Martínez, Pablo ^LU ; Eliasson, Lena ^LU and Lagerstedt, Jens O. ^LU (2024) In PLoS ONE 19(11 November).
- Contribution to journal › Article
Mark Antibodies targeting the shared cytokine receptor IL-1 receptor accessory protein invoke distinct mechanisms to block all cytokine signaling
Fields, James K. ; Gyllenbäck, Elin Jaensson ^LU ; Bogacz, Marek ; Obi, Juliet ; Birkedal, Gabriel Svensson ^LU ; Sjöström, Kjell ; Maravillas, Kino ; Grönberg, Caitríona ^LU ; Rattik, Sara ^LU and Kihn, Kyle , et al. (2024) In Cell Reports 43(5).
- Contribution to journal › Article
2023
Mark Skin mesenchymal niches maintain and protect AML-initiating stem cells
Sandhow, Lakshmi ; Cai, Huan ; Leonard, Elory ; Xiao, Pingnan ; Tomaipitinca, Luana ; Månsson, Alma ; Kondo, Makoto ; Sun, Xiaoyan ; Johansson, Anne Sofie and Tryggvason, Karl , et al. (2023) In Journal of Experimental Medicine 220(10).
- Contribution to journal › Article
Mark Combined GLUT1 and OXPHOS inhibition eliminates acute myeloid leukemia cells by restraining their metabolic plasticity
Rodriguez-Zabala, Maria ^LU ; Ramakrishnan, Ramprasad ^LU ; Reinbach, Katrin ^LU ; Ghosh, Somadri ^LU ; Oburoglu, Leal ^LU ; Falqués-Costa, Antoni ; Bellamkonda, Kishan ^LU ; Ehinger, Mats ^LU ; Peña-Martínez, Pablo ^LU and Puente-Moncada, Noelia ^LU , et al. (2023) In Blood Advances 7(18). p.5382-5395
- Contribution to journal › Article
Mark CRISPR Screens Identify Candidate Therapeutic Targets in Leukemia
Rodriguez Zabala, Maria ^LU (2023) In Lund University, Faculty of Medicine Doctoral Dissertation Series
- Thesis › Doctoral thesis (compilation)

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