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- 2008
-
Mark
The biological and ethical basis of the use of human embryonic stem cells for in vitro test systems or cell therapy
(
- Contribution to journal › Article
-
Mark
Increased thirst and drinking in Huntington's disease and the R6/2 mouse
(
- Contribution to journal › Article
-
Mark
Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation.
(
- Contribution to journal › Article
-
Mark
Increased metabolism in the R6/2 mouse model of Huntington's disease.
(
- Contribution to journal › Article
-
Mark
A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease.
(
- Contribution to journal › Article
- 2007
-
Mark
Large stem cell grafts could lead to erroneous interpretations of behavioral results?
(
- Contribution to journal › Letter
-
Mark
Reduced expression of PSA-NCAM in the hippocampus and piriform cortex of the R6/1 and R6/2 mouse models of Huntington's disease.
(
- Contribution to journal › Article
-
Mark
Restorative cell therapy for Parkinson's disease: A quest for the perfect cell
(
- Contribution to journal › Scientific review
-
Mark
Adult neurogenesis in neurodegenerative diseases
2007) p.445-445(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Decreased VIP and VPAC(2) receptor expression in the biological clock of the R6/2 Huntington's disease mouse
(
- Contribution to journal › Article
-
Mark
Fibroblast growth factor-20 increases the yield of midbrain dopaminergic neurons derived from human embryonic stem cells.
(
- Contribution to journal › Article
-
Mark
"NeuroStem Chip": a novel highly specialized tool to study neural differentiation pathways in human stem cells.
(
- Contribution to journal › Article
-
Mark
Tyrosine hydroxylase expression is unstable in a human immortalized mesencephalic cell line - Studies in vitro and after intracerebral grafting in vivo
(
- Contribution to journal › Article
-
Mark
Cocaine- and amphetamine-regulated transcript is increased in Huntington disease.
(
- Contribution to journal › Article
-
Mark
Midbrain expression of Delta-like 1 homologue is regulated by GDNF and is associated with dopaminergic differentiation.
(
- Contribution to journal › Article
-
Mark
Loss of SNAP-25 and rabphilin 3a in sensory-motor cortex in Huntington's disease.
(
- Contribution to journal › Article
- 2006
-
Mark
Therapeutic potential of controlled drug delivery systems in neurodegenerative diseases.
(
- Contribution to journal › Scientific review
-
Mark
On the move to stimulate cell plasticity in the substantia nigra in Parkinson's disease.
(
- Contribution to journal › Letter
-
Mark
Working memory training decreases hippocampal neurogenesis.
(
- Contribution to journal › Article
-
Mark
The impact of graft size on the development of dyskinesia following intrastriatal grafting of embryonic dopamine neurons in the rat.
(
- Contribution to journal › Article
-
Mark
Enriched Environment Attenuates Cell Genesis in Subventricular Zone After Focal Ischemia in Mice and Decreases Migration of Newborn Cells to the Striatum.
(
- Contribution to journal › Article
-
Mark
Transplantation in Parkinson's disease: The future looks bright.
(
- Contribution to journal › Article
-
Mark
High-fat diet impairs hippocampal neurogenesis in male rats.
(
- Contribution to journal › Article
-
Mark
Endothelial proliferation and increased blood-brain barrier permeability in the basal ganglia in a rat model of 3,4-dihydroxyphenyl-L-alanine-induced dyskinesia.
(
- Contribution to journal › Article
-
Mark
Failure of transdifferentiation of adult hematopoietic stem cells into neurons.
(
- Contribution to journal › Article
-
Mark
Cerebrospinal fluid levels of orexin-A are not a clinically useful biomarker for Huntington disease.
(
- Contribution to journal › Letter
-
Mark
Induction of dopaminergic neurons from growth factor expanded neural stem/progenitor cell cultures derived from human first trimester forebrain.
(
- Contribution to journal › Article
-
Mark
Progressive alterations in the hypothalamic-pituitary-adrenal axis in the R6/2 transgenic mouse model of Huntington's disease
(
- Contribution to journal › Article
-
Mark
Cholinergic neuronal defect without cell loss in Huntington's disease.
(
- Contribution to journal › Article
-
Mark
Transplantation of human embryonic stem cell-derived cells to a rat model of Parkinson's disease: Effect of in vitro differentiation on graft survival and teratoma formation
(
- Contribution to journal › Article
- 2005
-
Mark
Stromal cell-derived inducing activity does not promote dopaminergic differentiation, but enhances differentiation and proliferation of neural stem cell-derived astrocytes.
(
- Contribution to journal › Article
-
Mark
The use of the R6 transgenic mouse models of Huntington's disease in attempts to develop novel therapeutic strategies.
(
- Contribution to journal › Article
-
Mark
Synaptic dysfunction in Huntington's disease: a new perspective
(
- Contribution to journal › Scientific review
-
Mark
Lentiviral gene delivery of GDNF into the striatum of R6/2 Huntington mice fails to attenuate behavioral and neuropathological changes.
(
- Contribution to journal › Article
-
Mark
Stem cell-based therapy for Parkinson's disease.
(
- Contribution to journal › Scientific review
-
Mark
Behavioral characterization of a unilateral 6-OHDA-lesion model of Parkinson's disease in mice.
(
- Contribution to journal › Article
-
Mark
Platelet-Derived Growth Factor (PDGF-BB) and Brain-Derived Neurotrophic Factor (BDNF) induce striatal neurogenesis in adult rats with 6-hydroxydopamine lesions.
(
- Contribution to journal › Article
-
Mark
Combining neuroprotective treatment of embryonic nigral donor tissue with mild hypothermia of the graft recipient.
(
- Contribution to journal › Article
-
Mark
Depletion of rabphilin 3A in a transgenic mouse model (R6/1) of Huntington's disease, a possible culprit in synaptic dysfunction.
(
- Contribution to journal › Article
-
Mark
Evidence for dopaminergic re-innervation by embryonic allografts in an optimized rat model of the Parkinsonian variant of multiple system atrophy.
(
- Contribution to journal › Article
-
Mark
Reduced hippocampal neurogenesis in R6/2 transgenic Huntington's disease mice.
(
- Contribution to journal › Article
-
Mark
Progressive degeneration of human mesencephalic neuron-derived cells triggered by dopamine-dependent oxidative stress is dependent on the mixed-lineage kinase pathway
(
- Contribution to journal › Article
-
Mark
Proteolysis of NR2B by calpain in the hippocampus of epileptic rats.
(
- Contribution to journal › Article
-
Mark
Reduction of GnRH and infertility in the R6/2 mouse model of Huntington's disease.
(
- Contribution to journal › Article
-
Mark
The R6/2 transgenic mouse model of Huntington's disease develops diabetes due to deficient {beta}-cell mass and exocytosis.
(
- Contribution to journal › Article
-
Mark
Increased fiber outgrowth from xeno-transplanted human embryonic dopaminergic neurons with co-implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor.
(
- Contribution to journal › Article
-
Mark
Orexin loss in Huntington's disease.
(
- Contribution to journal › Article
- 2004
-
Mark
Harnessing endogenous stem cells to treat neurodegenerative disorders of the basal ganglia.
(
- Contribution to journal › Article
-
Mark
No evidence for new dopaminergic neurons in the adult mammalian substantia nigra.
(
- Contribution to journal › Article
-
Mark
Stem cell therapy for Parkinson's disease: where do we stand?
(
- Contribution to journal › Scientific review
-
Mark
Asialoerythropoetin is not effective in the R6/2 line of Huntington's disease mice
(
- Contribution to journal › Article
- 2003
-
Mark
The ubiquitin proteasome system in neurodegenerative diseases: Sometimes the chicken, sometimes the egg
(
- Contribution to journal › Scientific review
-
Mark
Grafting dopamine neurons in Parkinson's disease: do stem cells have a role in the future?
(
- Contribution to journal › Article
-
Mark
Fria radikaler och sjuka proteiner - bovarna bakom Parkinsons sjukdom?[Free radicals and ailing proteins - the culprits behind Parkinson’s disease?]
(
- Contribution to journal › Article
-
Mark
Huntington's disease: a synaptopathy?
(
- Contribution to journal › Article
-
Mark
Ultrastructural characterization of dissociated embryonic ventral mesencephalic tissue treated with neuroprotectants.
(
- Contribution to journal › Article
-
Mark
Cyclosporin A and Bcl-2 do not inhibit quinolinic acid-induced striatal excitotoxicity in rodents
(
- Contribution to journal › Article
-
Mark
Overexpression of heat shock protein 70 in R6/2 Huntington's disease mice has only modest effects on disease progression.
(
- Contribution to journal › Article
-
Mark
Both apoptosis and necrosis occur early after intracerebral grafting of ventral mesencephalic tissue: a role for protease activation.
(
- Contribution to journal › Article
-
Mark
Neural transplantation for the treatment of Parkinson's disease
(
- Contribution to journal › Debate/Note/Editorial
- 2002
-
Mark
GDNF treatment in Parkinson's disease: time for controlled clinical trials?
(
- Contribution to journal › Letter
-
Mark
Impaired dopamine storage resulting from alpha-synuclein mutations may contribute to the pathogenesis of Parkinson's disease.
(
- Contribution to journal › Scientific review
-
Mark
Huntington's disease: the mystery unfolds?
(
- Contribution to journal › Scientific review
-
Mark
Pathogenesis of Parkinson's disease: dopamine, vesicles and alpha-synuclein.
(
- Contribution to journal › Scientific review
-
Mark
Funding embryonic stem-cell research: will commerce counteract collaboration?
(
- Contribution to journal › Letter
-
Mark
Characterisation of cell damage and death in embryonic mesencephalic tissue: a study on ultrastructure, vital stains and protease activity.
(
- Contribution to journal › Article
-
Mark
Stem cells: hype or hope?
(
- Contribution to journal › Scientific review
-
Mark
Comparison between survival of lazaroid-treated embryonic nigral neurons in cell suspensions, cultures and transplants.
(
- Contribution to journal › Article
-
Mark
Effects of antioxidant pretreatment on the survival of embryonic dopaminergic neurons in vitro and following grafting in an animal model of Parkinson's disease
(
- Contribution to journal › Article
-
Mark
Maintenance of susceptibility to neurodegeneration following intrastriatal injections of quinolinic acid in a new transgenic mouse model of Huntington's disease.
(
- Contribution to journal › Article
-
Mark
Effect of mutant alpha-synuclein on dopamine homeostasis in a new human mesencephalic cell line.
(
- Contribution to journal › Article
-
Mark
Evidence for Dysfunction of the Nigrostriatal Pathway in the R6/1 Line of Transgenic Huntington's Disease Mice.
(
- Contribution to journal › Article
-
Mark
Increased Sensitivity to N-Methyl-D-Aspartate Receptor-Mediated Excitotoxicity in a Mouse Model of Huntington's Disease.
(
- Contribution to journal › Article
-
Mark
Dyskinesias following neural transplantation in Parkinson's disease.
(
- Contribution to journal › Article
- 2001
-
Mark
The neurobiology of cell transplantation in Parkinson's disease
(
- Contribution to journal › Article
-
Mark
Cell survival and clinical outcome following intrastriatal transplantation in Parkinson disease
(
- Contribution to journal › Article
-
Mark
Huntingtons sjukdom - ännu ett galet protein?
(
- Contribution to journal › Article
-
Mark
Altered striatal amino acid neurotransmitter release monitored using microdialysis in R6/1 Huntington transgenic mice
(
- Contribution to journal › Article
-
Mark
Partial resistance to malonate-induced striatal cell death in transgenic mouse models of Huntington's disease is dependent on age and CAG repeat length
(
- Contribution to journal › Article
-
Mark
Expanded CAG repeats in exon 1 of the Huntington's disease gene stimulate dopamine-mediated striatal neuron autophagy and degeneration
(
- Contribution to journal › Article
-
Mark
Brain-derived neurotrophic factor inhibits apoptosis and dopamine-induced free radical production in striatal neurons but does not prevent cell death
(
- Contribution to journal › Article
-
Mark
Resistance to NMDA toxicity correlates with appearance of nuclear inclusions, behavioural deficits and changes in calcium homeostasis in mice transgenic for exon 1 of the huntington gene
(
- Contribution to journal › Article
-
Mark
Mice transgenic for exon 1 of the Huntington's disease gene display reduced striatal sensitivity to neurotoxicity induced by dopamine and 6-hydroxydopamine
(
- Contribution to journal › Article
- 2000
-
Mark
FK506 and cyclosporin A enhance the survival of cultured and grafted rat embryonic dopamine neurons
(
- Contribution to journal › Article
-
Mark
Improving the survival of grafted embryonic dopamine neurons in rodent models of Parkinson's disease
(
- Contribution to journal › Article
-
Mark
Grafting of nigral tissue hibernated with tirilazad mesylate and glial cell line-derived neurotrophic factor
(
- Contribution to journal › Article
-
Mark
Increased survival of embryonic nigral neurons when grafted to hypothermic rats
(
- Contribution to journal › Article
-
Mark
Oxidative stress, mitochondrial permeability transition and activation of caspases in calcium ionophore A23187-induced death of cultured striatal neurons
(
- Contribution to journal › Article
-
Mark
Pretreatment with MK-801 or the lazaroid U-83836E does not enhance striatal graft survival
(
- Contribution to journal › Article
-
Mark
Caspase inhibition increases embryonic striatal graft survival
(
- Contribution to journal › Article
-
Mark
Additive effects of caspase inhibitor and lazaroid on the survival of transplanted rat and human embryonic dopamine neurons
(
- Contribution to journal › Article
-
Mark
Improving the survival of grafted dopaminergic neurons: a review over current approaches
(
- Contribution to journal › Article
-
Mark
Delayed recovery of movement-related cortical function in Parkinson's disease after striatal dopaminergic grafts
(
- Contribution to journal › Article
-
Mark
Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease
(
- Contribution to journal › Article
- 1999
-
Mark
Flunarizine improves the survival of grafted dopaminergic neurons
(
- Contribution to journal › Letter
-
Mark
Graft survival
(
- Contribution to journal › Letter
-
Mark
Patterns of cell death and dopaminergic neuron survival in intrastriatal nigral grafts
(
- Contribution to journal › Article
-
Mark
Grafts of Embryonic Dopamine Neurons in Rodent Models of Parkinson's Disease
1999) p.299-299(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Caspase inhibition reduces apoptosis and increases survival of nigral transplants
(
- Contribution to journal › Article
-
Mark
Transgenic mice expressing a Huntington's disease mutation are resistant to quinolinic acid-induced striatal excitotoxicity
(
- Contribution to journal › Article