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- 2019
- Maintenance of near normal bone mass and architecture in lethally irradiated female mice following adoptive transfer with as few as 750 purified hematopoietic stem cells
- 2018
- The Impact of Amyloid Peptides on Pericytes in Alzheimer's Disease
- Mitophagy : A Mechanism for Plant Growth and Survival
- 2017
- HAMLET – A protein-lipid complex with broad tumoricidal activity
- Smac and Smac mimetics in breast cancer cell death
-
Ca2+ involvement in activation of extracellular-signalregulated- kinase 1/2 and m-calpain after axotomy of the sciatic nerve
Mårtensson, Lisa B. LU ; Blom, Charlotta Lindwall and Dahlin, Lars B. LU
(2017)
In Neural Regeneration Research
12(4).
p.623-628
Mark
- 2016
- Cellular targets of HAMLET, their role in tumor cell death and therapeutic potential
- Global binding pattern of the Wilms' tumor gene 1 (WT1) +17AA -KTS isoform in leukemic cells
- 2015
-
Sensitive detection of lysosomal membrane permeabilization by lysosomal galectin puncta assay
Aits, Sonja LU
; Kricker, Jennifer
; Liu, Bin
; Ellegaard, Anne Marie
; Hämälistö, Saara
; Tvingsholm, Siri
; Corcelle-Termeau, Elisabeth
; Høgh, Søren
; Farkas, Thomas
and Jonassen, Anna Holm
, et al.
(2015)
In Autophagy
11(8).
p.1408-1424
Mark
- 2014
-
Extracellular hemoglobin - mediator of inflammation and cell death in the choroid plexus following preterm intraventricular hemorrhage
Gram, Magnus LU
; Sveinsdottir, Snjolaug
LU
; Cinthio, Magnus
LU
; Sveinsdottir, Kristbjörg
LU
; Hansson, Stefan
LU
; Mörgelin, Matthias
LU
; Åkerström, Bo
LU
and Ley, David
LU
(2014)
In Journal of Neuroinflammation
11.
Mark
- Novel In Situ Activity Assays for the Quantitative Molecular Analysis of Neurodegenerative Processes in the Retina
- The mitochondrial outer membrane AAA ATPase AtOM66 affects cell death and pathogen resistance in Arabidopsis thaliana
- IL-17 protects T cells from apoptosis and contributes to development of ALPS-like phenotypes
- 2013
- Roles of protein kinase C in cell death and breast cancer
-
Endothelial Cell Death and Intimal Foam Cell Accumulation in the Coronary Artery of Infected Hypercholesterolemic Minipigs
Birck, Malene M. ; Saraste, Antti ; Hyttel, Poul ; Odermarsky, Michal LU
; Liuba, Petru
LU
; Saukko, Pekka
; Hansen, Axel K.
and Pesonen, Erkki
LU
(2013)
In Journal of Cardiovascular Translational Research
6(4).
p.579-587
Mark
- 2012
- The mechanism of HAMLET-induced cell death - cellular signalling, oncogenes and clinical perspectives
- Identification of a novel protein kinase Cδ-Smac complex that dissociates during paclitaxel-induced cell death.
-
A novel initiation mechanism of death in Streptococcus pneumoniae induced by the human milk protein-lipid complex HAMLET and activated during physiological death
Clementi, Emily A ; Marks, Laura R ; Duffey, Michael E and Hakansson, Anders P LU
(2012)
In Journal of Biological Chemistry
287(32).
p.82-27168
Mark
-
Oleic acid is a key cytotoxic component of HAMLET-like complexes
Permyakov, Sergei E ; Knyazeva, Ekaterina L ; Khasanova, Leysan M ; Fadeev, Roman S ; Zhadan, Andrei P ; Roche-Hakansson, Hazeline ; Håkansson, Anders P LU
; Akatov, Vladimir S
and Permyakov, Eugene A
(2012)
In Biological Chemistry
393(1-2).
p.85-92
Mark
- 2011
-
Monomeric C-reactive protein modulates classic complement activation on necrotic cells
Mihlan, Michael ; Blom, Anna LU
; Kupreishvili, Koba
; Lauer, Nadine
; Stelzner, Kristin
; Mohlin, Frida
LU
; Niessen, Hans W. M.
and Zipfel, Peter F.
(2011)
In FASEB Journal
25(12).
p.4198-4210
Mark
- On the function of the interferon-inducible p53 target gene TRIM22
-
A novel method for preparation of HAMLET-like protein complexes
Permyakov, Sergei E ; Knyazeva, Ekaterina L ; Leonteva, Marina V ; Fadeev, Roman S ; Chekanov, Aleksei V ; Zhadan, Andrei P ; Håkansson, Anders P LU
; Akatov, Vladimir S
and Permyakov, Eugene A
(2011)
In Biochimie
93(9).
p.501-1495
Mark
- Cellular interactions of HAMLET and their role in cell death
-
Survival of rat pancreatic islets is partly controlled by a TCF7L2-p53-p53INP1 dependent pathway
Zhou, Y. LU ; Zhang, Enming LU ; Berggreen, C. LU ; Jing, Xingjun LU ; Osmark, P. LU ; Lang, S. LU
; Cilio, C.
LU
; Göransson, O.
LU
; Groop, L.
LU
and Renström, E.
LU
, et al.
(2011)
In Diabetologia
54.
p.64-65
Mark
- 2010
- Calcium-induced mitochondrial permeability transition in CNS-derived mitochondria - Pharmacological aspects of specificity and toxicity in neuroprotection
- Antitumor and anti-inflammatory effects of trabectedin on human myxoid liposarcoma cells
-
Mechanisms of HAMLET-induced cancer cell death
Aits, Sonja LU
(2010)
In Lund University Faculty of Medicine Doctoral Dissertation Series
2010:53.
Mark
- 2009
- Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells
- 2008
- Atypical retinoids ST1926 and CD437 are S-phase-specific agents causing DNA double-strand breaks : significance for the cytotoxic and antiproliferative activity
- 2007
- Arsenic trioxide and neuroblastoma cytotoxicity.
- Combined flow cytometry and confocal laser scanning microscopy for evaluation of BR96 antibody cancer cell targeting and internalization.
- Calpain activity in retinal degeneration.
-
Spinal cord mitochondria display lower calcium retention capacity compared with brain mitochondria without inherent differences in sensitivity to cyclophilin D inhibition
Morota, Saori ; Hansson, Magnus LU ; Ishii, Nagao ; Kudo, Yoshihisa ; Elmer, Eskil LU
and Uchino, Hiroyuki
(2007)
In Journal of Neurochemistry
103(5).
p.2066-2076
Mark
- OxLDL-induced gene expression patterns in CASMC are mimicked in apoE(-/-) mice aortas
- Dynamics of cell cycle phase perturbations by trabectedin (ET-743) in nucleotide excision repair (NER)-deficient and NER-proficient cells, unravelled by a novel mathematical simulation approach
- 2006
- Differential polyamine analogue effects in four human breast cancer cell lines
- Genetically determined susceptibility to neurodegeneration is associated with expression of inflammatory genes
- Antitumor activity of the retinoid-related molecules (E)-3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid (ST1926) and 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437) in F9 teratocarcinoma : Role of retinoic acid receptor gamma and retinoid-independent pathways
- Ventral tegmental area dopamine neurons are resistant to human mutant alpha-synuclein overexpression.
-
Effects of the selective cyclooxygenase-2 inhibitor rofecoxib on cell death following traumatic brain injury in the rat
Kunz, Tina ; Marklund, Niklas LU
; Hillered, Lars
and Oliw, Ernst H
(2006)
In Restorative Neurology and Neuroscience
24(1).
p.55-63
Mark
- 2005
- Role of mitochondria in tamoxifen-induced rapid death of MCF-7 breast cancer cells
- Lipopolysaccharide induces cell death in cultured porcine myenteric neurons.
- Effects of arsenic trioxide and hypoxia in multidrug-resistant neuroblastoma
-
Assessment of the effects of the cyclooxygenase-2 inhibitor rofecoxib on visuospatial learning and hippocampal cell death following kainate-induced seizures in the rat
Kunz, Tina ; Marklund, Niklas LU
; Hillered, Lars
and Oliw, Ernst H
(2005)
In Cognitive Brain Research
25(3).
p.32-826
Mark
- 2004
- Protein Kinase C-γ and Calcium/Calmodulin-Dependent Protein Kinase II-α Are Persistently Translocated to Cell Membranes of the Rat Brain during and after Middle Cerebral Artery Occlusion
- Development and Characterization of a Global Brain Ischemia Model in the Mouse -A Genetic and Pharmacological Approach
-
Serum cathepsin B activity during regression of Morris hepatoma 5123 D
Fedorowski, Artur LU
; Steciwko, Andrzej
and Rabczyński, Jerzy
(2004)
In Medical Science Monitor
10(5).
p.50-144
Mark
- 2003
- Apoptosis in male germ cells in response to cyclin A1-deficiency and cell cycle arrest
- Structural and functional damage sustained by mitochondria after traumatic brain injury in the rat: Evidence for differentially sensitive populations in the cortex and hippocampus
-
From cell death to neuronal regeneration : building a new brain after traumatic brain injury
Royo, Nicolas C ; Schouten, Joost W ; Fulp, Carl T ; Shimizu, Saori ; Marklund, Niklas LU
; Graham, David I
and McIntosh, Tracy K
(2003)
In Journal of Neuropathology and Experimental Neurology
62(8).
p.11-801
Mark
- Rat retinal ganglion cells upregulate the pro-apoptotic BH3-only protein Bim after optic nerve transection
- Experimental Traumatic Brain Injury and Cell Death - in vivo and in vitro aspects
- 2002
-
Increased Sensitivity to N-Methyl-D-Aspartate Receptor-Mediated Excitotoxicity in a Mouse Model of Huntington's Disease.
Zeron, Melinda M ; Hansson, Oskar LU
; Chen, Nansheng
; Wellington, Cheryl L
; Leavitt, Blair R
; Brundin, Patrik
LU
; Hayden, Michael R
and Raymond, Lynn A
(2002)
In Neuron
33(6).
p.849-860
Mark
- Maintenance of susceptibility to neurodegeneration following intrastriatal injections of quinolinic acid in a new transgenic mouse model of Huntington's disease.
- Papel del poro de permeabilidad transitoria mitocondrial en los procesos neurodegenerativos
- Deep brain stimulation of subthalamic neurons increases striatal dopamine metabolism and induces contralateral circling in freely moving 6-hydroxydopamine-lesioned rats
- 2001
-
Partial resistance to malonate-induced striatal cell death in transgenic mouse models of Huntington's disease is dependent on age and CAG repeat length
Hansson, Oskar LU
; Castilho, Roger F
; Korhonen, Laura
; Lindholm, Dan
; Bates, Gillian P
and Brundin, Patrik
LU
(2001)
In Journal of Neurochemistry
78(4).
p.694-703
Mark
- Adult rabbit retinal transplants
-
Delayed infusion of GDNF promotes recovery of motor function in the partial lesion model of Parkinson's disease
Kirik, Deniz LU ; Georgievska, Biljana LU ; Rosenblad, Carl and Björklund, Anders LU
(2001)
In European Journal of Neuroscience
13(8).
p.1589-1599
Mark
-
Mice transgenic for exon 1 of the Huntington's disease gene display reduced striatal sensitivity to neurotoxicity induced by dopamine and 6-hydroxydopamine
Petersén, Åsa LU ; Hansson, Oskar LU
; Puschban, Zoe
LU
; Sapp, Ellen
; Romero, Norma
; Castilho, Roger F.
; Sulzer, David
; Rice, Margaret
; DiFiglia, Marian
and Przedborski, Serge
, et al.
(2001)
In European Journal of Neuroscience
14(9).
p.1425-1435
Mark
- Restorative and neuroprotective treatment strategies for Parkinson’s disease: tudies on fetal dopamine cell transplants and GDNF delivery by intracerebral injections and recombinant AAV vectors.
-
Resistance to NMDA toxicity correlates with appearance of nuclear inclusions, behavioural deficits and changes in calcium homeostasis in mice transgenic for exon 1 of the huntington gene
Hansson, Oskar LU
; Guatteo, Ezia
; Mercuri, Nicola B
; Bernardi, Giorgio
; Li, Xiao-Jiang
; Castilho, Roger F
and Brundin, Patrik
LU
(2001)
In European Journal of Neuroscience
14(9).
p.1492-1504
Mark
- 2000
-
Improving the survival of grafted dopaminergic neurons: a review over current approaches
Brundin, Patrik LU ; Karlsson, Jenny LU ; Emgård-Mattson, Mia LU ; Schierle, Gabriele LU ; Hansson, Oskar LU
; Petersén, Åsa
LU
and Castilho, Roger F
(2000)
In Cell Transplantation
9(2).
p.179-195
Mark
- Subcellular distribution and autophosphorylation of calcium/calmodulin- dependent protein kinase II-α in rat hippocampus in a model of ischemic tolerance
-
FK506 and cyclosporin A enhance the survival of cultured and grafted rat embryonic dopamine neurons
Castilho, Roger F ; Hansson, Oskar LU
and Brundin, Patrik
LU
(2000)
In Experimental Neurology
164(1).
p.94-101
Mark
-
Oxidative stress, mitochondrial permeability transition and activation of caspases in calcium ionophore A23187-induced death of cultured striatal neurons
Petersén, Åsa LU ; Castilho, Roger F. ; Hansson, Oskar LU
; Wieloch, Tadeusz
LU
and Brundin, Patrik
LU
(2000)
In Brain Research
857(1-2).
p.20-29
Mark
- Phospholipase A2 in nerve injury and axonal outgrowth
- 1999
-
Patterns of cell death and dopaminergic neuron survival in intrastriatal nigral grafts
Emgård-Mattson, Mia LU ; Karlsson, Jenny LU ; Hansson, Oskar LU
and Brundin, Patrik
LU
(1999)
In Experimental Neurology
160(1).
p.88-279
Mark
- Ischemic Tolerance and Cell Signaling in the Rat Brain
- Upregulation of cytosolic phospholipase A2 correlates with apoptosis in mouse superior cervical and dorsal root ganglia neurons
- Rapid decline in protein kinase Cγ levels in the synaptosomal fraction of rat hippocampus after ischemic preconditioning
- Changes in protein tyrosine phosphorylation in the rat brain after cerebral ischemia in a model of ischemic tolerance
- Activation of the extracellular signal-regulated protein kinase cascade in the hippocampal CA1 region in a rat model of global cerebral ischemic preconditioning
- 1998
- Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death
- 1997
- DNA fragmentation and ultrastructural changes of degenerating cells in atherosclerotic lesions and smooth muscle cells exposed to oxidized LDL in vitro
- 1996
- MHC class I-induced apoptosis in hematopoietic cells
- Antioxidant treatment protects striatal neurons against excitotoxic insults
- 1994
- Changes in the Tyrosine Phosphorylation of Mitogen‐Activated Protein Kinase in the Rat Hippocampus During and Following Severe Hypoglycemia
- 1993
- Casein Kinase II Activity in the Postischemic Rat Brain Increases in Brain Regions Resistant to Ischemia and Decreases in Vulnerable Areas
- 1992
- Human fibroblasts lacking trans-stilbene oxide active glutathione transferase exhibit increased cell death when exposed to polycyclic aromatic hydrocarbons
- 1989
- Impairment of protein ubiquitination may cause delayed neuronal death