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2023
Mark Type 2 diabetes candidate genes, including PAX5, cause impaired insulin secretion in human pancreatic islets
Bacos, Karl ^LU ; Perfilyev, Alexander ^LU ; Karagiannopoulos, Alexandros ^LU ; Cowan, Elaine ^LU ; Ofori, Jones K ^LU ; Bertonnier-Brouty, Ludivine ^LU ; Rönn, Tina ^LU ; Lindqvist, Andreas ^LU ; Luan, Cheng ^LU and Ruhrmann, Sabrina ^LU , et al. (2023) In The Journal of clinical investigation 133(4).
- Contribution to journal › Article
2022
Mark Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets
Golec, Ewelina ^LU ; Ekström, Alexander ^LU ; Noga, Maciej ^LU ; Omar-Hmeadi, Muhmmad ; Lund, Per-Eric ; Villoutreix, Bruno O ; Krus, Ulrika ^LU ; Wozniak, Katarzyna ^LU ; Korsgren, Olle and Renström, Erik ^LU , et al. (2022) In Proceedings of the National Academy of Sciences of the United States of America 119(24).
- Contribution to journal › Article
Mark A critical role of the mechanosensor PIEZO1 in glucose-induced insulin secretion in pancreatic β-cells
Ye, Yingying ^LU ; Barghouth, Mohammad ^LU ; Dou, Haiqiang ; Luan, Cheng ^LU ; Wang, Yongzhi ^LU ; Karagiannopoulos, Alexandros ^LU ; Jiang, Xiaoping ^LU ; Krus, Ulrika ^LU ; Fex, Malin ^LU and Zhang, Quan , et al. (2022) In Nature Communications 13(1).
- Contribution to journal › Article
Mark Islet Gene View-a tool to facilitate islet research
Asplund, Olof ^LU ; Storm, Petter ^LU ; Chandra, Vikash ; Hatem, Gad ^LU ; Ottosson-Laakso, Emilia ^LU ; Mansour-Aly, Dina ^LU ; Krus, Ulrika ^LU ; Ibrahim, Hazem ; Ahlqvist, Emma ^LU and Tuomi, Tiinamaija ^LU , et al. (2022) In Life Science Alliance 5(12).
- Contribution to journal › Article
2021
Mark Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability
Lagou, Vasiliki ; Krus, Ulrika ^LU ; Groop, Leif ^LU ; Tuomi, Tiinamaija ^LU ; Lyssenko, Valeriya ^LU and Prokopenko, Inga (2021) In Nature Communications 12(1).
- Contribution to journal › Article
2020
Mark Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D
Viñuela, Ana ; Varshney, Arushi ; van de Bunt, Martijn ; Prasad, Rashmi B ^LU ; Asplund, Olof ^LU ; Bennett, Amanda ; Boehnke, Michael ; Brown, Andrew A ; Erdos, Michael R and Fadista, João ^LU , et al. (2020) In Nature Communications 11(1). p.4912-4912
- Contribution to journal › Article
2019
Mark Complement Component C3 Is Highly Expressed in Human Pancreatic Islets and Prevents β Cell Death via ATG16L1 Interaction and Autophagy Regulation
King, Ben ^LU ; Kulak, Klaudia ^LU ; Krus, Ulrika ^LU ; Rosberg, Rebecca ^LU ; Golec, Ewelina ^LU ; wozniak, katarzyna ^LU ; Gomez, Maria ^LU ; Zhang, Enming ^LU ; O'Connell, David J and Renström, Erik ^LU , et al. (2019) In Cell Metabolism 29(1). p.6-210
- Contribution to journal › Article
Mark Decreased Expression of Cilia Genes in Pancreatic Islets as a Risk Factor for Type 2 Diabetes in Mice and Humans
Kluth, Oliver ; Stadion, Mandy ; Gottmann, Pascal ; Aga, Heja ; Jähnert, Markus ; Scherneck, Stephan ; Vogel, Heike ; Krus, Ulrika ^LU ; Seelig, Anett and Ling, Charlotte ^LU , et al. (2019) In Cell Reports 26(11). p.3-3036
- Contribution to journal › Article
Mark Loss of ZnT8 function protects against diabetes by enhanced insulin secretion
Dwivedi, Om Prakash ; Lehtovirta, Mikko ; Hastoy, Benoit ; Chandra, Vikash ; Krentz, Nicole A. J. ; Kleiner, Sandra ; Jain, Deepak ^LU ; Richard, Ann-Marie ; Abaitua, Fernando and Beer, Nicola L. , et al. (2019) In Nature Genetics p.1-22
- Contribution to journal › Article
2017
Mark Glucose-induced Changes in Gene Expression in Human Pancreatic Islets - Causes or Consequences of Chronic Hyperglycemia
Ottosson-Laakso, Emilia ^LU ; Krus, Ulrika ^LU ; Storm, Petter ^LU ; Prasad, Rashmi B ^LU ; Oskolkov, Nikolay ^LU ; Ahlqvist, Emma ^LU ; Fadista, João ^LU ; Hansson, Ola ^LU ; Groop, Leif ^LU and Vikman, Petter ^LU (2017) In Diabetes 66(12). p.3013-3028
- Contribution to journal › Article

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