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- 2024
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Mark
Predicting type 2 diabetes via machine learning integration of multiple omics from human pancreatic islets
(
- Contribution to journal › Article
- 2023
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Mark
Type 2 diabetes candidate genes, including PAX5, cause impaired insulin secretion in human pancreatic islets
(
- Contribution to journal › Article
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Mark
Circulating triglycerides are associated with human adipose tissue DNA methylation of genes linked to metabolic disease
(
- Contribution to journal › Article
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Mark
Genes with epigenetic alterations in human pancreatic islets impact mitochondrial function, insulin secretion, and type 2 diabetes
(
- Contribution to journal › Article
- 2022
-
Mark
Epigenetic epidemiology and alterations in type 2 diabetes and obesity
2022) p.445-474(
- Chapter in Book/Report/Conference proceeding › Book chapter
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Mark
Epigenetics of type 2 diabetes mellitus and weight change — a tool for precision medicine?
(
- Contribution to journal › Scientific review
- 2020
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Mark
Epigenetic changes in islets of langerhans preceding the onset of diabetes
(
- Contribution to journal › Article
- 2019
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Mark
Fasting unmasks differential fat and muscle transcriptional regulation of metabolic gene sets in low versus normal birth weight men
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- Contribution to journal › Article
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Mark
ATAC-seq reveals alterations in open chromatin in pancreatic islets from subjects with type 2 diabetes.
(
- Contribution to journal › Article
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Mark
Epigenetics in Human Obesity and Type 2 Diabetes
(
- Contribution to journal › Scientific review
- 2017
-
Mark
Epigenetic alterations in blood mirror age-associated DNA methylation and gene expression changes in human liver
(
- Contribution to journal › Article
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Mark
Whole-genome Bisulfite Sequencing of Human Pancreatic Islets Reveals Novel Differentially Methylated Regions in Type 2 Diabetes Pathogenesis
(
- Contribution to journal › Article
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Mark
Human liver epigenetic alterations in non-alcoholic steatohepatitis are related to insulin action
(
- Contribution to journal › Article
- 2016
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Mark
Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding.
(
- Contribution to journal › Article
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Mark
Epigenetic markers to further understand insulin resistance
(
- Contribution to journal › Debate/Note/Editorial
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Mark
A genome-wide mQTL analysis in human adipose tissue identifies genetic variants associated with DNA methylation, gene expression and metabolic traits
(
- Contribution to journal › Article
- 2015
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Mark
Genome-wide analysis of DNA methylation in subjects with type 1 diabetes identifies epigenetic modifications associated with proliferative diabetic retinopathy.
(
- Contribution to journal › Article
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Mark
Less pronounced response to exercise in healthy relatives to type 2 diabetics compared to controls.
(
- Contribution to journal › Article
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Mark
Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood.
(
- Contribution to journal › Article
-
Mark
DNA methylation as a diagnostic and therapeutic target in the battle against Type 2 diabetes.
(
- Contribution to journal › Scientific review
-
Mark
Genome-Wide DNA and Histone Modification Studies in Metabolic Disease
2015) p.255-270(
- Chapter in Book/Report/Conference proceeding › Book chapter
- 2014
-
Mark
Effects of palmitate on genome-wide mRNA expression and DNA methylation patterns in human pancreatic islets.
(
- Contribution to journal › Article
-
Mark
Sex differences in the genome-wide DNA methylation pattern and impact on gene expression, microRNA levels and insulin secretion in human pancreatic islets
(
- Contribution to journal › Article
-
Mark
Epigenetic adaptation to regular exercise in humans.
(
- Contribution to journal › Scientific review
-
Mark
Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion.
(
- Contribution to journal › Article
-
Mark
Genome-Wide Associations between Genetic and Epigenetic Variation Influence mRNA Expression and Insulin Secretion in Human Pancreatic Islets.
(
- Contribution to journal › Article
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Mark
Altered DNA methylation and differential expression of genes influencing metabolism and inflammation in adipose tissue from subjects with type 2 diabetes.
(
- Contribution to journal › Article
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Mark
Leveraging cross-species transcription factor binding site patterns: from diabetes risk Loci to disease mechanisms.
(
- Contribution to journal › Article
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Mark
Extensive changes in the transcriptional profile of human adipose tissue including genes involved in oxidative phosphorylation after a six months exercise intervention.
(
- Contribution to journal › Article
-
Mark
Expression of Phosphofructokinase in Skeletal Muscle Is Influenced by Genetic Variation and Associated With Insulin Sensitivity
(
- Contribution to journal › Article
- 2013
-
Mark
Effect of exercise on DNA methylation and metabolism in human adipose tissue and skeletal muscle.
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
A six months exercise intervention influences the genome-wide DNA methylation pattern in human adipose tissue.
(
- Contribution to journal › Article
-
Mark
Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets.
(
- Contribution to journal › Article
- 2012
-
Mark
First-Degree Relatives of Type 2 Diabetic Patients Have Reduced Expression of Genes Involved in Fatty Acid Metabolism in Skeletal Muscle.
(
- Contribution to journal › Article
-
Mark
Impact of an Exercise Intervention on DNA Methylation in Skeletal Muscle From First-Degree Relatives of Patients With Type 2 Diabetes.
2012) In Diabetes(
- Contribution to journal › Article
-
Mark
Telomere length in blood and skeletal muscle in relation to measures of glycaemia and insulinaemia.
(
- Contribution to journal › Article
- 2011
-
Mark
Two common genetic variants near nuclear encoded OXPHOS genes are associated with insulin secretion in vivo.
(
- Contribution to journal › Article
-
Mark
The expression of myosin heavy chain (MHC) genes in human skeletal muscle is related to metabolic characteristics involved in the pathogenesis of type 2 diabetes.
(
- Contribution to journal › Article
-
Mark
A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes.
(
- Contribution to journal › Article
- 2010
-
Mark
The role of genetic variation and DNA methylation in human glucose metabolism and type 2 diabetes
(
- Thesis › Doctoral thesis (compilation)
-
Mark
Investigation of Type 2 Diabetes Risk Alleles Support CDKN2A/B, CDKAL1, and TCF7L2 As Susceptibility Genes in a Han Chinese Cohort
(
- Contribution to journal › Article
-
Mark
Resistance to exercise-induced changes in the global DNA methylation pattern of skeletal muscle in individuals with a family history of type 2 diabetes
2010) 46th Annual Meeting of the European-Association-for-the- Study-of-Diabetes (EASD) In Diabetologia 53(Suppl. 1). p.312-312(
- Contribution to journal › Published meeting abstract
-
Mark
Deoxyribonucleic Acid Methylation and Gene Expression of PPARGC1A in Human Muscle Is Influenced by High-Fat Overfeeding in a Birth-Weight-Dependent Manner.
(
- Contribution to journal › Article
- 2009
-
Mark
A common variant in MTNR1B, encoding melatonin receptor 1B, is associated with type 2 diabetes and fasting plasma glucose in Han Chinese individuals.
(
- Contribution to journal › Article
-
Mark
Unique splicing pattern of the TCF7L2 gene in human pancreatic islets.
(
- Contribution to journal › Article
-
Mark
Genetic variation in ATP5O is associated with skeletal muscle ATP50 mRNA expression and glucose uptake in young twins.
(
- Contribution to journal › Article
- 2008
-
Mark
PGC-1 alpha and PGC-1 beta are related to markers for fibre type composition in human skeletal muscle
2008) 44th EASD Annual Meeting of the European Association for the Study of Diabetes In Diabetologia 51(S1). p.130-130(
- Contribution to journal › Published meeting abstract
-
Mark
Genetic variation in ATP5O is associated with mRNA expression in human skeletal muscle and in vivo glucose uptake
2008) 44th EASD Annual Meeting of the European Association for the Study of Diabetes In Diabetologia 51(Supplement 1). p.132-132(
- Contribution to journal › Published meeting abstract
-
Mark
Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion.
(
- Contribution to journal › Article
-
Mark
Age influences DNA methylation and gene expression of COX7A1 in human skeletal muscle.
(
- Contribution to journal › Article
- 2007
-
Mark
Genetic and epigenetic factors are associated with expression of respiratory chain component NDUFB6 in human skeletal muscle
(
- Contribution to journal › Article