Publications | Lund University Publications

Increased expression of ORMDL3 in allergic asthma : a case control and in vitro study Nowakowska, Joanna ; Olechnowicz, Anna ; Langwiński, Wojciech ; Koteluk, Oliwia ; Lemańska, Żaneta ; Jóźwiak, Kacper ; Kamiński, Kacper ; Łosiewski, Wojciech ; Stegmayr, John ^LU and Wagner, Darcy ^LU

, et al. (2023) In Journal of Asthma 60(3). p.458-467

Contribution to journal › Article

Modeling fibrotic alveolar transitional cells with pluripotent stem cell-derived alveolar organoids Ptasinski, Victoria ^LU ; Monkley, Susan J. ; Öst, Karolina ; Tammia, Markus ; Alsafadi, Hani N. ^LU

; Overed-Sayer, Catherine ; Hazon, Petra ; Wagner, Darcy E. ^LU

and Murray, Lynne A. (2023) In Life Science Alliance 6(8).

Contribution to journal › Article

Deep learning for rapid and reproducible histology scoring of lung injury in a porcine model Augusto Silva, Iran ^LU

; Kazemi Rashed, Salma ^LU ; Hedlund, Ludwig ; Lidfeldt, August ; Gvazava, Nika ^LU ; Stegmayr, John ^LU ; Skoryk, Valeriia ^LU ; Aits, Sonja ^LU

and Wagner, Darcy ^LU

(2023)

Working paper/Preprint › Preprint in preprint archive

ERS International Congress 2022 : highlights from the Basic and Translational Science Assembly Cuevas Ocaña, Sara ; El-Merhie, Natalia ; Kuipers, Merian E ; Lehmann, Mareike ; Enes, Sara Rolandsson ^LU

; Voss, Carola ; Dean, Lareb S N ; Loxham, Matthew ; Boots, Agnes W and Cloonan, Suzanne M , et al. (2023) In ERJ open research 9(2).

Contribution to journal › Scientific review

Formalin-free fixation and xylene-free tissue processing preserves cell-hydrogel interactions for histological evaluation of 3D calcium alginate tissue engineered constructs Augusto Silva, Iran ^LU

; Gvazava, Nika ^LU ; Wendi, Indra Putra ^LU ; Guinea Ordonez, Rodrigo Jose ^LU

; Garcia Gimenez, Francisco ^LU ; Stegmayr, John ^LU ; Klementieva, Oxana ^LU

and Wagner, Darcy ^LU

(2023) In Frontiers in Biomaterials Science 2-2023(1155919).

Contribution to journal › Article

Label-FreeHigh-ResolutionPhotothermalOpticalInfraredSpectroscopyfor Spatiotemporal Chemica lAnalysis in Fresh, Hydrated Living Tissues and Embryos Gvazava, Nika ^LU ; Konings, Sabine ^LU

; Cepeda-Prado, Efrain ^LU

; Skoryk, Valeriia ^LU ; Harrison Umeano, Chimezie ^LU ; Dong, Jiao ^LU

; Augusto Silva, Iran ^LU

; Rylander Ottosson, Daniella ^LU

; Leigh, Nicholas ^LU

and Wagner, Darcy ^LU

, et al. (2023) In Journal of the American Chemical Society

Contribution to journal › Article

KRAS signaling in malignant pleural mesothelioma Marazioti, Antonia ; Krontira, Anthi C ; Behrend, Sabine J ; Giotopoulou, Georgia A ; Ntaliarda, Giannoula ; Blanquart, Christophe ; Bayram, Hasan ; Iliopoulou, Marianthi ; Vreka, Malamati and Trassl, Lilith , et al. (2022) In EMBO Molecular Medicine 14(2).

Contribution to journal › Article

Allergic inflammation in lungs and nasal epithelium of rat model is regulated by tissue-specific miRNA expression Langwiński, Wojciech ; Szczepankiewicz, Dawid ; Narożna, Beata ; Stegmayr, John ^LU ; Wagner, Darcy ^LU

; Alsafadi, Hani ^LU

; Lindstedt, Sandra ^LU ; Stachowiak, Zuzanna ; Nowakowska, Joanna and Skrzypski, Marek , et al. (2022) In Molecular Immunology 147. p.115-125

Contribution to journal › Article

Corticotropin releasing hormone as an identifier of bronchiolitis obliterans syndrome Niroomand, Anna ^LU ; Ghaidan, Haider ^LU

; Hallgren, Oskar ^LU ; Hansson, Lennart ^LU ; Larsson, Hillevi ^LU ; Wagner, Darcy ^LU

; Mackova, Martina ; Halloran, Kieran ; Hyllén, Snejana ^LU and Lindstedt, Sandra ^LU (2022) In Scientific Reports 12. p.1-11

Contribution to journal › Article

Reduction of primary graft dysfunction using cytokine adsorption during organ preservation and after lung transplantation Ghaidan, Haider ^LU

; Stenlo, Martin ^LU ; Niroomand, Anna ^LU ; Mittendorfer, Margareta ^LU ; Hirdman, Gabriel ^LU ; Gvazava, Nika ^LU ; Edström, Dag ^LU ; Augusto Silva, Iran ^LU

; Broberg, Ellen ^LU and Hallgren, Oskar ^LU , et al. (2022) In Nature Communications 13(1).

Contribution to journal › Article

A Semi-quantitative Scoring System for Green Histopathological Evaluation of Large Animal Models of Acute Lung Injury Augusto Silva, Iran ^LU

; Gvazava, Nika ^LU ; Bölükbas, Deniz ^LU ; Stenlo, Martin ^LU ; Dong, Jiao ^LU

; Pierre, Leif ^LU ; Lindstedt, Sandra ^LU and Wagner, Darcy ^LU

(2022) In Bio-protocol 12(16).

Contribution to journal › Article

Advanced manufacturing: three-dimensional printing and bioprinting of models of lung and airways Tas, Sinem ^LU ; Rehnberg, Emil ^LU and Wagner, Darcy E. ^LU

(2022) p.171-195

Chapter in Book/Report/Conference proceeding › Book chapter

Simultaneous isolation of proximal and distal lung progenitor cells from individual mice using a 3D printed guide reduces proximal cell contamination of distal lung epithelial cell isolations Alsafadi, Hani N ^LU

; Stegmayr, John ^LU ; Ptasinski, Victoria ^LU ; Silva, Iran ^LU

; Mittendorfer, Margareta ^LU ; Murray, Lynne A and Wagner, Darcy E ^LU

(2022) In Stem Cell Reports 17(12). p.2718-2731

Contribution to journal › Article

How to peer review : practical advice for early career researchers Mathioudakis, Alexander G. ; Wagner, Darcy ^LU

and Dumas, Orianne (2022) In Breathe 18(4).

Contribution to journal › Debate/Note/Editorial

Extracellular-Matrix-Reinforced Bioinks for 3D Bioprinting Human Tissue De Santis, Martina M ^LU

; Alsafadi, Hani N ^LU

; Tas, Sinem ^LU ; Bölükbas, Deniz A ^LU ; Prithiviraj, Sujeethkumar ^LU ; Da Silva, Iran A ^LU

; Mittendorfer, Margareta ^LU ; Ota, Chiharu ; Stegmayr, John ^LU and Daoud, Fatima ^LU , et al. (2021) In Advanced Materials 33(3).

Contribution to journal › Article

A Biomimetic, Copolymeric Membrane for Cell-Stretch Experiments with Pulmonary Epithelial Cells at the Air-Liquid Interface Doryab, Ali ; Taskin, Mehmet Berat ; Stahlhut, Philipp ; Schröppel, Andreas ; Wagner, Darcy E. ^LU

; Groll, Jürgen and Schmid, Otmar (2021) In Advanced Functional Materials 31(10).

Contribution to journal › Article

Isolation of high yield and quality RNA from human precision-cut lung slices for RNA-sequencing and computational integration with larger patient cohorts Stegmayr, John ^LU ; Alsafadi, Hani N ^LU

; Langwinski, Wojciech ^LU ; Niroomand, Anna ^LU ; Lindstedt, Sandra ^LU ; Leigh, Nicholas D ^LU

and Wagner, Darcy E ^LU

(2021) In American Journal of Physiology: Lung Cellular and Molecular Physiology 320(2). p.232-240

Contribution to journal › Article

Lung transplant after 6 months on ECMO support for SARS-CoV-2-induced ARDS complicated by severe antibody-mediated rejection Lindstedt, Sandra ^LU ; Grins, Edgar ^LU

; Larsson, Hillevi ^LU ; Nilsson, Johan ^LU

; Akbarshahi, Hamid ^LU ; Silva, Iran ^LU

; Hyllen, Snejana ^LU ; Wagner, Darcy ^LU

; Sjögren, Johan ^LU and Hansson, Lennart ^LU , et al. (2021) In BMJ Open Respiratory Research 8. p.1-4

Contribution to journal › Article

The dawn of the omics era in human precision-cut lung slices Stegmayr, John ^LU and Wagner, Darcy E ^LU

(2021) In The European respiratory journal 58(1).

Contribution to journal › Article

Targeting Alveolar Repair in Idiopathic Pulmonary Fibrosis Ptasinski, Victoria ^LU ; Stegmayr, John ^LU ; Belvisi, Maria G ; Wagner, Darcy E ^LU

and Murray, Lynne A (2021) In American Journal of Respiratory Cell and Molecular Biology 65(4). p.347-347

Contribution to journal › Article

Monitoring lung injury with particle flow rate in LPS- and COVID-19-induced ARDS Stenlo, Martin ^LU ; Augusto Silva, Iran ^LU

; Hyllén, Snejana ^LU ; Bölükbas, Deniz ^LU ; Niroomand, Anna ^LU ; Grins, Edgars ^LU

; Ederoth, Per ^LU ; Hallgren, Oskar ^LU ; Pierre, Leif ^LU and Wagner, Darcy ^LU

, et al. (2021) In Physiological Reports 9(13).

Contribution to journal › Article

Toxicological effects of zinc oxide nanoparticle exposure: an in vitro comparison between dry aerosol air-liquid interface and submerged exposure systems Lovén, Karin ^LU ; Dobric, Julia ^LU ; Bölükbas, Deniz ^LU ; Kåredal, Monica ^LU

; Tas, Sinem ^LU ; Rissler, Jenny ^LU ; Wagner, Darcy ^LU

and Isaxon, Christina ^LU (2021) In Nanotoxicology 15(4). p.494-510

Contribution to journal › Article

A drug screen with approved compounds identifies amlexanox as a novel Wnt/β-catenin activator inducing lung epithelial organoid formation Costa, Rita ; Wagner, Darcy E. ^LU

; Doryab, Ali ; De Santis, Martina M. ^LU

; Schorpp, Kenji ; Rothenaigner, Ina ; Lehmann, Mareike ; Baarsma, Hoeke A. ; Liu, Xueping and Schmid, Otmar , et al. (2021) In British Journal of Pharmacology 178(19). p.4026-4041

Contribution to journal › Article

Lung tissue bioengineering for transplantation and modelling of development, disease and regeneration De Santis, Martina M. ^LU

; Michielin, Federica ; Shibuya, Soichi ; Coppi, Paolo de and Wagner, Darcy E. ^LU

(2021) In ERS Monograph 2021(91). p.248-272

Contribution to journal › Article

Bioengineering Approaches for the Distal Lung Wagner, Darcy E. ^LU

(2021) 1. p.788-795

Chapter in Book/Report/Conference proceeding › Book chapter

Applications and Approaches for Three-Dimensional Precision-Cut Lung Slices. Disease Modeling and Drug Discovery Alsafadi, Hani N ^LU

; Uhl, Franziska E. ^LU ; Pineda, Ricardo H. ; Bailey, Kolene E. ; Rojas, Mauricio ; Wagner, Darcy E ^LU

and Königshoff, Melanie (2020) In American Journal of Respiratory Cell and Molecular Biology 62(6). p.681-691

Contribution to journal › Scientific review

Mechanically ventilated patients exhibit decreased particle flow in exhaled breath as compared to normal breathing patients Broberg, Ellen ^LU ; Andreasson, Jesper ^LU ; Fakhro, Mohammed ^LU ; Olin, Anna-Carin ; Wagner, Darcy ^LU

; Hyllén, Snejana ^LU and Lindstedt, Sandra ^LU (2020) In ERJ Open Research 6. p.1-10

Contribution to journal › Article

Increased particle flow rate from airways precedes clinical signs of ARDS in a porcine model of LPS-induced acute lung injury Stenlo, Martin ^LU ; Hyllén, Snejana ^LU ; Silva, Iran Augusto N ^LU

; Bölükbas, Deniz A ^LU ; Pierre, Leif T ^LU ; Hallgren, Oskar ^LU ; Wagner, Darcy E ^LU

and Lindstedt, Sandra ^LU (2020) In American Journal of Physiology: Lung Cellular and Molecular Physiology 318(3). p.510-517

Contribution to journal › Article

Fostering the integration of basic respiratory science and translational pulmonary medicine for the future Wagner, Darcy E ^LU

; Ubags, Niki D ; Troosters, Thierry and Alejandre Alcázar, Miguel A (2020) In American Journal of Physiology: Lung Cellular and Molecular Physiology 319(3). p.538-540

Contribution to journal › Debate/Note/Editorial

Lung regeneration : implications of the diseased niche and ageing Melo-Narváez, M. Camila ; Stegmayr, John ^LU ; Wagner, Darcy E. ^LU

and Lehmann, Mareike (2020) In European Respiratory Review 29(157).

Contribution to journal › Article

Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Disease 2019 Wagner, Darcy E ^LU

; Ikonomou, Laertis ; Gilpin, Sarah E ; Magin, Chelsea M ; Cruz, Fernanda ; Greaney, Allison ; Magnusson, Mattias ^LU ; Chen, Ya-Wen ; Davis, Brian and Vanuytsel, Kim , et al. (2020) In ERJ Open Research 6(4).

Contribution to journal › Scientific review

Inhibition of LTβR signalling activates WNT-induced regeneration in lung Conlon, Thomas M ; John-Schuster, Gerrit ; Heide, Danijela ; Pfister, Dominik ; Lehmann, Mareike ; Hu, Yan ; Ertüz, Zeynep ; Lopez, Martin A ; Ansari, Meshal and Strunz, Maximilian , et al. (2020) In Nature 588(7836). p.151-156

Contribution to journal › Article

Organ-Restricted Vascular Delivery of Nanoparticles for Lung Cancer Therapy Bölükbas, Deniz ^LU ; Datz, Stefan ; Meyer-Schwickerath, Charlotte ; Morrone, Carmela ; Doryab, Ali ; Gössl, Dorothee ; Vreka, Malamati ; Yang, Lin ; Argyo, Christian and van Rijt, Sabine , et al. (2020) In Advanced Therapeutics 3(7).

Contribution to journal › Article

Collagen IV : a critical new starting point for engineering upper airways De Santis, Martina M ^LU

and Wagner, Darcy E ^LU

(2020) In The European respiratory journal 55(6). p.1-4

Contribution to journal › Debate/Note/Editorial

Technological advances in study of lung regenerative medicine : perspective from the 2019 Vermont lung stem cell conference Ikonomou, Laertis ; Wagner, Darcy E ^LU

; Gilpin, Sarah E ; Weiss, Daniel J. and Ryan, Amy L (2020) In Cytotherapy 22(10). p.519-520

Contribution to journal › Debate/Note/Editorial

Clickable decellularized extracellular matrix as a new tool for building hybrid-hydrogels to model chronic fibrotic diseases in vitro Petrou, Cassandra L. ; D'Ovidio, Tyler J. ; Bölükbas, Deniz ^LU ; Tas, Sinem ^LU ; Brown, R. Dale ; Allawzi, Ayed ; Lindstedt Ingemansson, Sandra ^LU ; Nozik-Grayck, Eva ; Stenmark, Kurt R. and Wagner, Darcy ^LU

, et al. (2020) In Journal of Materials Chemistry B 8(31). p.6814-6826

Contribution to journal › Article

3D printing of decellularised porcine lung ECM Tas, Sinem ^LU ; Bölükbas, Deniz A. ^LU ; Alsafadi, Hani ^LU

and Wagner, Darcy E. ^LU

(2019) 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence 40. p.962-962

Chapter in Book/Report/Conference proceeding › Paper in conference proceeding

Translating Basic Research into Safe and Effective Cell-based Treatments for Respiratory Diseases Ikonomou, Laertis ; Wagner, Darcy E ^LU

; Turner, Leigh and Weiss, Daniel J (2019) In Annals of the American Thoracic Society 16(6). p.657-668

Contribution to journal › Scientific review

Generation of Human 3D Lung Tissue Cultures (3D-LTCs) for Disease Modeling Gerckens, Michael ; Alsafadi, Hani N ^LU

; Wagner, Darcy E ^LU

; Lindner, Michael ; Burgstaller, Gerald and Königshoff, Melanie (2019) In Journal of visualized experiments : JoVE

Contribution to journal › Article

The Preparation of Decellularized Mouse Lung Matrix Scaffolds for Analysis of Lung Regenerative Cell Potential Bölükbas, Deniz A. ^LU ; De Santis, Martina M. ^LU

; Alsafadi, Hani N. ^LU

; Doryab, Ali and Wagner, Darcy E. ^LU

(2019) In Methods in molecular biology (Clifton, N.J.) 1940. p.275-295

Contribution to journal › Article

Fine-tuning lung cancer nanotherapy using closed cardiopulmonary circulation Bölükbas, D. A. ^LU ; Morrone, C. ; Doryab, A. ; Datz, S. ; Gößl, D. ; Meyer-Schwickerath, C. ; Vreka, M. ; van Rijt, S. H. ; Stöger, T. and Stathopoulos, G. T. , et al. (2019) 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence 40.

Chapter in Book/Report/Conference proceeding › Paper in conference proceeding

Clickable, hybrid hydrogels as tissue culture platforms for modeling chronic pulmonary diseases in vitro Petrou, Cassandra L. ; Darling, Nicole J. ; Bölükbas, Deniz A. ^LU ; Wagner, Darcy E. ^LU

and Magin, Chelsea M. (2019) 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence 40.

Chapter in Book/Report/Conference proceeding › Paper in conference proceeding

Particle Flow Profiles From the Airways Measured by PExA Differ in Lung Transplant Recipients Who Develop Primary Graft Dysfunction Broberg, Ellen ^LU ; Hyllén, Snejana ^LU ; Algotsson, Lars ^LU ; Wagner, Darcy E ^LU

and Lindstedt, Sandra ^LU (2019) In Experimental and clinical transplantation 17(6). p.803-812

Contribution to journal › Article

Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Diseases 2017 : An Official American Thoracic Society Workshop Report Ryan, Amy L ; Ikonomou, Laertis ; Atarod, Sadaf ; Bölükbas, Deniz A ^LU ; Collins, Jennifer ; Freishtat, Rob ; Hawkins, Finn ; Gilpin, Sarah E ; Uhl, Franziska E ^LU and Uriarte, Juan Jose , et al. (2019) In American Journal of Respiratory Cell and Molecular Biology

Book/Report › Report

Evolution of Bioengineered Lung Models : Recent Advances and Challenges in Tissue Mimicry for Studying the Role of Mechanical Forces in Cell Biology Doryab, Ali ; Tas, Sinem ^LU ; Taskin, Mehmet Berat ; Yang, Lin ; Hilgendorff, Anne ; Groll, Jürgen ; Wagner, Darcy E. ^LU

and Schmid, Otmar (2019) In Advanced Functional Materials

Contribution to journal › Scientific review

Preclinical evidence for the role of stem/stromal cells in COPD Bölükbas, Deniz ^LU ; Augusto Silva, Iran ^LU

; Rydell-Törmänen, Kristina ^LU

and Wagner, Darcy ^LU

(2019) p.73-96

Chapter in Book/Report/Conference proceeding › Book chapter

The Oncogene ECT2 Contributes to a Hyperplastic, Proliferative Lung Epithelial Cell Phenotype in Idiopathic Pulmonary Fibrosis Ulke, Henrik M ; Mutze, Kathrin ; Lehmann, Mareike ; Wagner, Darcy E ^LU

; Heinzelmann, Katharina ; Günther, Andreas ; Eickelberg, Oliver and Königshoff, Melanie (2019) In American Journal of Respiratory Cell and Molecular Biology 61(6). p.713-726

Contribution to journal › Article

Club cells form lung adenocarcinomas and maintain the alveoli of adult mice Spella, Magda ; Lilis, Ioannis ; Pepe, Mario Aa ; Chen, Yuanyuan ; Armaka, Maria ; Lamort, Anne-Sophie ; Zazara, Dimitra E ; Roumelioti, Fani ; Vreka, Malamati and Kanellakis, Nikolaos I , et al. (2019) In eLife 8.

Contribution to journal › Article

X-Ray Dark-Field Imaging of Lung Cancer in Mice Bölükbas, Deniz ^LU and Wagner, Darcy ^LU

(2019)

Chapter in Book/Report/Conference proceeding › Book chapter

Co-opting of ClinicalTrials.gov by patient-funded studies Wagner, Darcy E. ^LU

; Turner, Leigh ; Panoskaltsis-Mortari, Angela ; Weiss, Daniel J. and Ikonomou, Laertis (2018) In The Lancet Respiratory Medicine 6(8). p.579-581

Contribution to journal › Debate/Note/Editorial