Publications | Lund University Publications

Modeling fibrotic alveolar transitional cells with pluripotent stem cell-derived alveolar organoids Ptasinski, Victoria ^LU ; Monkley, Susan J. ; Öst, Karolina ; Tammia, Markus ; Alsafadi, Hani N. ^LU

; Overed-Sayer, Catherine ; Hazon, Petra ; Wagner, Darcy E. ^LU

and Murray, Lynne A. (2023) In Life Science Alliance 6(8).

Contribution to journal › Article

Deep learning for rapid and reproducible histology scoring of lung injury in a porcine model Augusto Silva, Iran ^LU

; Kazemi Rashed, Salma ^LU ; Hedlund, Ludwig ; Lidfeldt, August ; Gvazava, Nika ^LU ; Stegmayr, John ^LU ; Skoryk, Valeriia ^LU ; Aits, Sonja ^LU

and Wagner, Darcy ^LU

(2023)

Working paper/Preprint › Preprint in preprint archive

Label-FreeHigh-ResolutionPhotothermalOpticalInfraredSpectroscopyfor Spatiotemporal Chemica lAnalysis in Fresh, Hydrated Living Tissues and Embryos Gvazava, Nika ^LU ; Konings, Sabine ^LU

; Cepeda-Prado, Efrain ^LU

; Skoryk, Valeriia ^LU ; Harrison Umeano, Chimezie ^LU ; Dong, Jiao ^LU

; Augusto Silva, Iran ^LU

; Rylander Ottosson, Daniella ^LU ; Leigh, Nicholas ^LU

and Wagner, Darcy ^LU

, et al. (2023) In Journal of the American Chemical Society

Contribution to journal › Article

Formalin-free fixation and xylene-free tissue processing preserves cell-hydrogel interactions for histological evaluation of 3D calcium alginate tissue engineered constructs Augusto Silva, Iran ^LU

; Gvazava, Nika ^LU ; Wendi, Indra Putra ^LU ; Guinea Ordonez, Rodrigo Jose ^LU

; Garcia Gimenez, Francisco ^LU ; Stegmayr, John ^LU ; Klementieva, Oxana ^LU

and Wagner, Darcy ^LU

(2023) In Frontiers in Biomaterials Science 2-2023(1155919).

Contribution to journal › Article

Increased expression of ORMDL3 in allergic asthma : a case control and in vitro study Nowakowska, Joanna ; Olechnowicz, Anna ; Langwiński, Wojciech ; Koteluk, Oliwia ; Lemańska, Żaneta ; Jóźwiak, Kacper ; Kamiński, Kacper ; Łosiewski, Wojciech ; Stegmayr, John ^LU and Wagner, Darcy ^LU

, et al. (2023) In Journal of Asthma 60(3). p.458-467

Contribution to journal › Article

ERS International Congress 2022 : highlights from the Basic and Translational Science Assembly Cuevas Ocaña, Sara ; El-Merhie, Natalia ; Kuipers, Merian E ; Lehmann, Mareike ; Enes, Sara Rolandsson ^LU

; Voss, Carola ; Dean, Lareb S N ; Loxham, Matthew ; Boots, Agnes W and Cloonan, Suzanne M , et al. (2023) In ERJ open research 9(2).

Contribution to journal › Scientific review

KRAS signaling in malignant pleural mesothelioma Marazioti, Antonia ; Krontira, Anthi C ; Behrend, Sabine J ; Giotopoulou, Georgia A ; Ntaliarda, Giannoula ; Blanquart, Christophe ; Bayram, Hasan ; Iliopoulou, Marianthi ; Vreka, Malamati and Trassl, Lilith , et al. (2022) In EMBO Molecular Medicine 14(2).

Contribution to journal › Article

Reduction of primary graft dysfunction using cytokine adsorption during organ preservation and after lung transplantation Ghaidan, Haider ^LU

; Stenlo, Martin ^LU ; Niroomand, Anna ^LU ; Mittendorfer, Margareta ^LU ; Hirdman, Gabriel ^LU ; Gvazava, Nika ^LU ; Edström, Dag ^LU ; Augusto Silva, Iran ^LU

; Broberg, Ellen ^LU and Hallgren, Oskar ^LU , et al. (2022) In Nature Communications 13(1).

Contribution to journal › Article

Allergic inflammation in lungs and nasal epithelium of rat model is regulated by tissue-specific miRNA expression Langwiński, Wojciech ; Szczepankiewicz, Dawid ; Narożna, Beata ; Stegmayr, John ^LU ; Wagner, Darcy ^LU

; Alsafadi, Hani ^LU

; Lindstedt, Sandra ^LU ; Stachowiak, Zuzanna ; Nowakowska, Joanna and Skrzypski, Marek , et al. (2022) In Molecular Immunology 147. p.115-125

Contribution to journal › Article

Corticotropin releasing hormone as an identifier of bronchiolitis obliterans syndrome Niroomand, Anna ^LU ; Ghaidan, Haider ^LU

; Hallgren, Oskar ^LU ; Hansson, Lennart ^LU ; Larsson, Hillevi ^LU ; Wagner, Darcy ^LU

; Mackova, Martina ; Halloran, Kieran ; Hyllén, Snejana ^LU and Lindstedt, Sandra ^LU (2022) In Scientific Reports 12. p.1-11

Contribution to journal › Article

Advanced manufacturing: three-dimensional printing and bioprinting of models of lung and airways Tas, Sinem ^LU ; Rehnberg, Emil ^LU and Wagner, Darcy E. ^LU

(2022) p.171-195

Chapter in Book/Report/Conference proceeding › Book chapter

Simultaneous isolation of proximal and distal lung progenitor cells from individual mice using a 3D printed guide reduces proximal cell contamination of distal lung epithelial cell isolations Alsafadi, Hani N ^LU

; Stegmayr, John ^LU ; Ptasinski, Victoria ^LU ; Silva, Iran ^LU

; Mittendorfer, Margareta ^LU ; Murray, Lynne A and Wagner, Darcy E ^LU

(2022) In Stem Cell Reports 17(12). p.2718-2731

Contribution to journal › Article

How to peer review : practical advice for early career researchers Mathioudakis, Alexander G. ; Wagner, Darcy ^LU

and Dumas, Orianne (2022) In Breathe 18(4).

Contribution to journal › Debate/Note/Editorial

A Semi-quantitative Scoring System for Green Histopathological Evaluation of Large Animal Models of Acute Lung Injury Augusto Silva, Iran ^LU

; Gvazava, Nika ^LU ; Bölükbas, Deniz ^LU ; Stenlo, Martin ^LU ; Dong, Jiao ^LU

; Pierre, Leif ^LU ; Lindstedt, Sandra ^LU and Wagner, Darcy ^LU

(2022) In Bio-protocol 12(16).

Contribution to journal › Article

Isolation of high yield and quality RNA from human precision-cut lung slices for RNA-sequencing and computational integration with larger patient cohorts Stegmayr, John ^LU ; Alsafadi, Hani N ^LU

; Langwinski, Wojciech ^LU ; Niroomand, Anna ^LU ; Lindstedt, Sandra ^LU ; Leigh, Nicholas D ^LU

and Wagner, Darcy E ^LU

(2021) In American Journal of Physiology: Lung Cellular and Molecular Physiology 320(2). p.232-240

Contribution to journal › Article

A drug screen with approved compounds identifies amlexanox as a novel Wnt/β-catenin activator inducing lung epithelial organoid formation Costa, Rita ; Wagner, Darcy E. ^LU

; Doryab, Ali ; De Santis, Martina M. ^LU

; Schorpp, Kenji ; Rothenaigner, Ina ; Lehmann, Mareike ; Baarsma, Hoeke A. ; Liu, Xueping and Schmid, Otmar , et al. (2021) In British Journal of Pharmacology 178(19). p.4026-4041

Contribution to journal › Article

Toxicological effects of zinc oxide nanoparticle exposure: an in vitro comparison between dry aerosol air-liquid interface and submerged exposure systems Lovén, Karin ^LU ; Dobric, Julia ^LU ; Bölükbas, Deniz ^LU ; Kåredal, Monica ^LU

; Tas, Sinem ^LU ; Rissler, Jenny ^LU ; Wagner, Darcy ^LU

and Isaxon, Christina ^LU (2021) In Nanotoxicology 15(4). p.494-510

Contribution to journal › Article

The dawn of the omics era in human precision-cut lung slices Stegmayr, John ^LU and Wagner, Darcy E ^LU

(2021) In The European respiratory journal 58(1).

Contribution to journal › Article

Targeting Alveolar Repair in Idiopathic Pulmonary Fibrosis Ptasinski, Victoria ^LU ; Stegmayr, John ^LU ; Belvisi, Maria G ; Wagner, Darcy E ^LU

and Murray, Lynne A (2021) In American Journal of Respiratory Cell and Molecular Biology 65(4). p.347-347

Contribution to journal › Article

Monitoring lung injury with particle flow rate in LPS- and COVID-19-induced ARDS Stenlo, Martin ^LU ; Augusto Silva, Iran ^LU

; Hyllén, Snejana ^LU ; Bölükbas, Deniz ^LU ; Niroomand, Anna ^LU ; Grins, Edgars ^LU

; Ederoth, Per ^LU ; Hallgren, Oskar ^LU ; Pierre, Leif ^LU and Wagner, Darcy ^LU

, et al. (2021) In Physiological Reports 9(13).

Contribution to journal › Article

Extracellular-Matrix-Reinforced Bioinks for 3D Bioprinting Human Tissue De Santis, Martina M ^LU

; Alsafadi, Hani N ^LU

; Tas, Sinem ^LU ; Bölükbas, Deniz A ^LU ; Prithiviraj, Sujeethkumar ^LU ; Da Silva, Iran A ^LU

; Mittendorfer, Margareta ^LU ; Ota, Chiharu ; Stegmayr, John ^LU and Daoud, Fatima ^LU , et al. (2021) In Advanced Materials 33(3).

Contribution to journal › Article

A Biomimetic, Copolymeric Membrane for Cell-Stretch Experiments with Pulmonary Epithelial Cells at the Air-Liquid Interface Doryab, Ali ; Taskin, Mehmet Berat ; Stahlhut, Philipp ; Schröppel, Andreas ; Wagner, Darcy E. ^LU

; Groll, Jürgen and Schmid, Otmar (2021) In Advanced Functional Materials 31(10).

Contribution to journal › Article

Bioengineering Approaches for the Distal Lung Wagner, Darcy E. ^LU

(2021) 1. p.788-795

Chapter in Book/Report/Conference proceeding › Book chapter

Lung transplant after 6 months on ECMO support for SARS-CoV-2-induced ARDS complicated by severe antibody-mediated rejection Lindstedt, Sandra ^LU ; Grins, Edgar ^LU

; Larsson, Hillevi ^LU ; Nilsson, Johan ^LU

; Akbarshahi, Hamid ^LU ; Silva, Iran ^LU

; Hyllen, Snejana ^LU ; Wagner, Darcy ^LU

; Sjögren, Johan ^LU and Hansson, Lennart ^LU , et al. (2021) In BMJ Open Respiratory Research 8. p.1-4

Contribution to journal › Article

Lung tissue bioengineering for transplantation and modelling of development, disease and regeneration De Santis, Martina M. ^LU

; Michielin, Federica ; Shibuya, Soichi ; Coppi, Paolo de and Wagner, Darcy E. ^LU

(2021) In ERS Monograph 2021(91). p.248-272

Contribution to journal › Article

Collagen IV : a critical new starting point for engineering upper airways De Santis, Martina M ^LU

and Wagner, Darcy E ^LU

(2020) In The European respiratory journal 55(6). p.1-4

Contribution to journal › Debate/Note/Editorial

Technological advances in study of lung regenerative medicine : perspective from the 2019 Vermont lung stem cell conference Ikonomou, Laertis ; Wagner, Darcy E ^LU

; Gilpin, Sarah E ; Weiss, Daniel J. and Ryan, Amy L (2020) In Cytotherapy 22(10). p.519-520

Contribution to journal › Debate/Note/Editorial

Fostering the integration of basic respiratory science and translational pulmonary medicine for the future Wagner, Darcy E ^LU

; Ubags, Niki D ; Troosters, Thierry and Alejandre Alcázar, Miguel A (2020) In American Journal of Physiology: Lung Cellular and Molecular Physiology 319(3). p.538-540

Contribution to journal › Debate/Note/Editorial

Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Disease 2019 Wagner, Darcy E ^LU

; Ikonomou, Laertis ; Gilpin, Sarah E ; Magin, Chelsea M ; Cruz, Fernanda ; Greaney, Allison ; Magnusson, Mattias ^LU ; Chen, Ya-Wen ; Davis, Brian and Vanuytsel, Kim , et al. (2020) In ERJ Open Research 6(4).

Contribution to journal › Scientific review

Lung regeneration : implications of the diseased niche and ageing Melo-Narváez, M. Camila ; Stegmayr, John ^LU ; Wagner, Darcy E. ^LU

and Lehmann, Mareike (2020) In European Respiratory Review 29(157).

Contribution to journal › Article

Mechanically ventilated patients exhibit decreased particle flow in exhaled breath as compared to normal breathing patients Broberg, Ellen ^LU ; Andreasson, Jesper ^LU ; Fakhro, Mohammed ^LU ; Olin, Anna-Carin ; Wagner, Darcy ^LU

; Hyllén, Snejana ^LU and Lindstedt, Sandra ^LU (2020) In ERJ Open Research 6. p.1-10

Contribution to journal › Article

Organ-Restricted Vascular Delivery of Nanoparticles for Lung Cancer Therapy Bölükbas, Deniz ^LU ; Datz, Stefan ; Meyer-Schwickerath, Charlotte ; Morrone, Carmela ; Doryab, Ali ; Gössl, Dorothee ; Vreka, Malamati ; Yang, Lin ; Argyo, Christian and van Rijt, Sabine , et al. (2020) In Advanced Therapeutics 3(7).

Contribution to journal › Article

Applications and Approaches for Three-Dimensional Precision-Cut Lung Slices. Disease Modeling and Drug Discovery Alsafadi, Hani N ^LU

; Uhl, Franziska E. ^LU ; Pineda, Ricardo H. ; Bailey, Kolene E. ; Rojas, Mauricio ; Wagner, Darcy E ^LU

and Königshoff, Melanie (2020) In American Journal of Respiratory Cell and Molecular Biology 62(6). p.681-691

Contribution to journal › Scientific review

Increased particle flow rate from airways precedes clinical signs of ARDS in a porcine model of LPS-induced acute lung injury Stenlo, Martin ^LU ; Hyllén, Snejana ^LU ; Silva, Iran Augusto N ^LU

; Bölükbas, Deniz A ^LU ; Pierre, Leif T ^LU ; Hallgren, Oskar ^LU ; Wagner, Darcy E ^LU

and Lindstedt, Sandra ^LU (2020) In American Journal of Physiology: Lung Cellular and Molecular Physiology 318(3). p.510-517

Contribution to journal › Article

Clickable decellularized extracellular matrix as a new tool for building hybrid-hydrogels to model chronic fibrotic diseases in vitro Petrou, Cassandra L. ; D'Ovidio, Tyler J. ; Bölükbas, Deniz ^LU ; Tas, Sinem ^LU ; Brown, R. Dale ; Allawzi, Ayed ; Lindstedt Ingemansson, Sandra ^LU ; Nozik-Grayck, Eva ; Stenmark, Kurt R. and Wagner, Darcy ^LU

, et al. (2020) In Journal of Materials Chemistry B 8(31). p.6814-6826

Contribution to journal › Article

Inhibition of LTβR signalling activates WNT-induced regeneration in lung Conlon, Thomas M ; John-Schuster, Gerrit ; Heide, Danijela ; Pfister, Dominik ; Lehmann, Mareike ; Hu, Yan ; Ertüz, Zeynep ; Lopez, Martin A ; Ansari, Meshal and Strunz, Maximilian , et al. (2020) In Nature 588(7836). p.151-156

Contribution to journal › Article

The Preparation of Decellularized Mouse Lung Matrix Scaffolds for Analysis of Lung Regenerative Cell Potential Bölükbas, Deniz A. ^LU ; De Santis, Martina M. ^LU

; Alsafadi, Hani N. ^LU

; Doryab, Ali and Wagner, Darcy E. ^LU

(2019) In Methods in molecular biology (Clifton, N.J.) 1940. p.275-295

Contribution to journal › Article

Generation of Human 3D Lung Tissue Cultures (3D-LTCs) for Disease Modeling Gerckens, Michael ; Alsafadi, Hani N ^LU

; Wagner, Darcy E ^LU

; Lindner, Michael ; Burgstaller, Gerald and Königshoff, Melanie (2019) In Journal of visualized experiments : JoVE

Contribution to journal › Article

Particle Flow Profiles From the Airways Measured by PExA Differ in Lung Transplant Recipients Who Develop Primary Graft Dysfunction Broberg, Ellen ^LU ; Hyllén, Snejana ^LU ; Algotsson, Lars ^LU ; Wagner, Darcy E ^LU

and Lindstedt, Sandra ^LU (2019) In Experimental and clinical transplantation 17(6). p.803-812

Contribution to journal › Article

Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Diseases 2017 : An Official American Thoracic Society Workshop Report Ryan, Amy L ; Ikonomou, Laertis ; Atarod, Sadaf ; Bölükbas, Deniz A ^LU ; Collins, Jennifer ; Freishtat, Rob ; Hawkins, Finn ; Gilpin, Sarah E ; Uhl, Franziska E ^LU and Uriarte, Juan Jose , et al. (2019) In American Journal of Respiratory Cell and Molecular Biology

Book/Report › Report

The Oncogene ECT2 Contributes to a Hyperplastic, Proliferative Lung Epithelial Cell Phenotype in Idiopathic Pulmonary Fibrosis Ulke, Henrik M ; Mutze, Kathrin ; Lehmann, Mareike ; Wagner, Darcy E ^LU

; Heinzelmann, Katharina ; Günther, Andreas ; Eickelberg, Oliver and Königshoff, Melanie (2019) In American Journal of Respiratory Cell and Molecular Biology 61(6). p.713-726

Contribution to journal › Article

Club cells form lung adenocarcinomas and maintain the alveoli of adult mice Spella, Magda ; Lilis, Ioannis ; Pepe, Mario Aa ; Chen, Yuanyuan ; Armaka, Maria ; Lamort, Anne-Sophie ; Zazara, Dimitra E ; Roumelioti, Fani ; Vreka, Malamati and Kanellakis, Nikolaos I , et al. (2019) In eLife 8.

Contribution to journal › Article

Fine-tuning lung cancer nanotherapy using closed cardiopulmonary circulation Bölükbas, D. A. ^LU ; Morrone, C. ; Doryab, A. ; Datz, S. ; Gößl, D. ; Meyer-Schwickerath, C. ; Vreka, M. ; van Rijt, S. H. ; Stöger, T. and Stathopoulos, G. T. , et al. (2019) 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence 40.

Chapter in Book/Report/Conference proceeding › Paper in conference proceeding

Clickable, hybrid hydrogels as tissue culture platforms for modeling chronic pulmonary diseases in vitro Petrou, Cassandra L. ; Darling, Nicole J. ; Bölükbas, Deniz A. ^LU ; Wagner, Darcy E. ^LU

and Magin, Chelsea M. (2019) 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence 40.

Chapter in Book/Report/Conference proceeding › Paper in conference proceeding

3D printing of decellularised porcine lung ECM Tas, Sinem ^LU ; Bölükbas, Deniz A. ^LU ; Alsafadi, Hani ^LU

and Wagner, Darcy E. ^LU

(2019) 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence 40. p.962-962

Chapter in Book/Report/Conference proceeding › Paper in conference proceeding

Evolution of Bioengineered Lung Models : Recent Advances and Challenges in Tissue Mimicry for Studying the Role of Mechanical Forces in Cell Biology Doryab, Ali ; Tas, Sinem ^LU ; Taskin, Mehmet Berat ; Yang, Lin ; Hilgendorff, Anne ; Groll, Jürgen ; Wagner, Darcy E. ^LU

and Schmid, Otmar (2019) In Advanced Functional Materials

Contribution to journal › Scientific review

Translating Basic Research into Safe and Effective Cell-based Treatments for Respiratory Diseases Ikonomou, Laertis ; Wagner, Darcy E ^LU

; Turner, Leigh and Weiss, Daniel J (2019) In Annals of the American Thoracic Society 16(6). p.657-668

Contribution to journal › Scientific review

X-Ray Dark-Field Imaging of Lung Cancer in Mice Bölükbas, Deniz ^LU and Wagner, Darcy ^LU

(2019)

Chapter in Book/Report/Conference proceeding › Book chapter

Preclinical evidence for the role of stem/stromal cells in COPD Bölükbas, Deniz ^LU ; Augusto Silva, Iran ^LU

; Rydell-Törmänen, Kristina ^LU

and Wagner, Darcy ^LU

(2019) p.73-96

Chapter in Book/Report/Conference proceeding › Book chapter

TGF-β1-induced deposition of provisional extracellular matrix by tracheal basal cells promotes epithelial-to-mesenchymal transition in a c-Jun NH₂-terminal kinase-1-dependent manner van der Velden, Jos L. ; Wagner, Darcy E. ^LU

; Lahue, Karolyn G. ; Abdalla, Sarah T. ; Lam, Ying Wai ; Weiss, Daniel J. and Janssen-Heininger, Yvonne M.W. (2018) In American Journal of Physiology: Lung Cellular and Molecular Physiology 314(6). p.984-997

Contribution to journal › Article

Acellular human lung scaffolds to model lung disease and tissue regeneration Gilpin, Sarah E. and Wagner, Darcy E. ^LU

(2018) In European Respiratory Review 27(148).

Contribution to journal › Scientific review

How to build a lung : latest advances and emerging themes in lung bioengineering De Santis, Martina M ^LU

; Bölükbas, Deniz A ^LU ; Lindstedt, Sandra ^LU and Wagner, Darcy E ^LU

(2018) In European Respiratory Journal 52. p.1-19

Contribution to journal › Scientific review

S100a4 Is Secreted by Alternatively Activated Alveolar Macrophages and Promotes Activation of Lung Fibroblasts in Pulmonary Fibrosis Zhang, Wei ^LU ; Ohno, Shinji ; Steer, Beatrix ; Klee, Stephan ; Staab-Weijnitz, Claudia A ; Wagner, Darcy ^LU

; Lehmann, Mareike ; Stoeger, Tobias ; Königshoff, Melanie and Adler, Heiko (2018) In Frontiers in Immunology 9. p.1-14

Contribution to journal › Article

Avian lungs : A novel scaffold for lung bioengineering Wrenn, Sean M ; Griswold, Ethan D ; Uhl, Franziska E ^LU ; Uriarte, Juan J ; Park, Heon E ; Coffey, Amy L ; Dearborn, Jacob S ; Ahlers, Bethany A ; Deng, Bin and Lam, Ying-Wai , et al. (2018) In PLoS ONE 13(6). p.0198956-0198956

Contribution to journal › Article

Increased Extracellular Vesicles Mediate WNT-5A Signaling in Idiopathic Pulmonary Fibrosis Martin-Medina, Aina ; Lehmann, Mareike ; Burgy, Olivier ; Hermann, Sarah ; Baarsma, Hoeke A ; Wagner, Darcy E ^LU

; De Santis, Martina M ^LU

; Ciolek, Florian ; Hofer, Thomas P and Frankenberger, Marion , et al. (2018) In American Journal of Respiratory and Critical Care Medicine 198(12). p.1527-1538

Contribution to journal › Article

A new way of monitoring mechanical ventilation by measurement of particle flow from the airways using Pexa method in vivo and during ex vivo lung perfusion in DCD lung transplantation Broberg, Ellen ^LU ; Wlosinska, Martiné ^LU ; Algotsson, Lars ^LU ; Olin, Anna-Carin ; Wagner, Darcy ^LU

; Pierre, Leif ^LU and Lindstedt, Sandra ^LU (2018) In Intensive Care Medicine Experimental 6(1). p.1-19

Contribution to journal › Article

Dynamic expression of HOPX in alveolar epithelial cells reflects injury and repair during the progression of pulmonary fibrosis Ota, Chiharu ; Ng-Blichfeldt, John-Poul ; Korfei, Martina ; Alsafadi, Hani N. ^LU

; Lehmann, Mareike ; Skronska-Wasek, Wioletta ; De Santis, Martina M. ^LU

; Guenther, Andreas ; Wagner, Darcy ^LU

and Königshoff, Melanie (2018) In Scientific Reports 8.

Contribution to journal › Article

Two succeeding fibroblastic lineages drive dermal development and the transition from regeneration to scarring Jiang, Dongsheng ; Correa-Gallegos, Donovan ; Christ, Simon ; Stefanska, Ania ; Liu, Juan ; Ramesh, Pushkar ; Rajendran, Vijayanand ; De Santis, Martina M. ^LU

; Wagner, Darcy E. ^LU

and Rinkevich, Yuval (2018) In Nature Cell Biology 20(4). p.422-431

Contribution to journal › Article

Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis 11 Medical and Health Sciences 1102 Cardiorespiratory Medicine and Haematology 06 Biological Sciences 0601 Biochemistry and Cell Biology Lehmann, Mareike ; Buhl, Lara ; Alsafadi, Hani N. ^LU

; Klee, Stephan ; Hermann, Sarah ; Mutze, Kathrin ; Ota, Chiharu ; Lindner, Michael ; Behr, Jürgen and Hilgendorff, Anne , et al. (2018) In Respiratory Research 19(1).

Contribution to journal › Article

Co-opting of ClinicalTrials.gov by patient-funded studies Wagner, Darcy E. ^LU

; Turner, Leigh ; Panoskaltsis-Mortari, Angela ; Weiss, Daniel J. and Ikonomou, Laertis (2018) In The Lancet Respiratory Medicine 6(8). p.579-581

Contribution to journal › Debate/Note/Editorial

Human pulmonary 3D models for translational research Zscheppang, Katja ; Berg, Johanna ; Hedtrich, Sarah ; Verheyen, Leonie ; Wagner, Darcy E ^LU

; Suttorp, Norbert ; Hippenstiel, Stefan and Hocke, Andreas C (2018) In Biotechnology Journal 13(1).

Contribution to journal › Scientific review

Early Career Members at the ERS LSC 2017 : mechanistic overlap between chronic lung injury and cancer Almendros, Isaac ; Bartel, Sabine ; Bostantzoglou, Clementine ; Jubrail, Jamil ; Lehmann, Mareike and Wagner, Darcy ^LU

(2017) In Breathe 13(4). p.323-326

Contribution to journal › Debate/Note/Editorial

Preparation of Decellularized Lung Matrices for Cell Culture and Protein Analysis Uhl, Franziska E ^LU ; Wagner, Darcy E ^LU

and Weiss, Daniel J. (2017) In Methods in Molecular Biology 1627. p.253-283

Contribution to journal › Article

Unproven Stem Cell Treatments for Lung Disease-An Emerging Public Health Problem Ikonomou, Laertis ; Panoskaltsis-Mortari, Angela ; Wagner, Darcy E. ^LU

; Freishtat, Robert J. and Weiss, Daniel J. (2017) In American Journal of Respiratory and Critical Care Medicine 195(7). p.13-14

Contribution to journal › Debate/Note/Editorial

Heterozygous Vangl2Looptail mice reveal novel roles for the planar cell polarity pathway in adult lung homeostasis and repair Poobalasingam, Thanushiyan ; Yates, Laura L. ; Walker, Simone A. ; Pereira, Miguel ; Gross, Nina Y. ; Ali, Akmol ; Kolatsi-Joannou, Maria ; Jarvelin, Marjo Riitta ; Pekkanen, Juha and Papakrivopoulou, Eugenia , et al. (2017) In DMM Disease Models and Mechanisms 10(4). p.409-423

Contribution to journal › Article

Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD Baarsma, Hoeke A. ; Skronska-Wasek, Wioletta ; Mutze, Kathrin ; Ciolek, Florian ; Wagner, Darcy E. ^LU

; John-Schuster, Gerrit ; Heinzelmann, Katharina ; Günther, Andreas ; Bracke, Ken R. and Dagouassat, Maylis , et al. (2017) In Journal of Experimental Medicine 214(1). p.143-163

Contribution to journal › Article

An ex vivo model to induce early fibrosis-like changes in human precision-cut lung slices Alsafadi, Hani N. ^LU

; Staab-Weijnitz, Claudia A. ; Lehmann, Mareike ; Lindner, Michael ; Peschel, Britta ; Königshoff, Melanie and Wagner, Darcy E. ^LU

(2017) In American Journal of Physiology: Lung Cellular and Molecular Physiology 312(6). p.896-902

Contribution to journal › Article

Reduced frizzled receptor 4 expression prevents WNT/b-catenin-driven alveolar lung repair in chronic obstructive pulmonary disease Skronska-Wasek, Wioletta ; Mutze, Kathrin ; Baarsma, Hoeke A. ; Bracke, Ken R. ; Alsafadi, Hani N. ^LU

; Lehmann, Mareike ; Costa, Ana Rita ; Stornaiuolo, Mariano ; Novellino, Ettore and Brusselle, Guy , et al. (2017) In American Journal of Respiratory and Critical Care Medicine 196(2). p.172-185

Contribution to journal › Article

Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo Lehmann, Mareike ; Korfei, Martina ; Mutze, Kathrin ; Klee, Stephan ; Skronska-Wasek, Wioletta ; Alsafadi, Hani N. ^LU

; Ota, Chiharu ; Costa, Ana Rita ; Schiller, Herbert B and Lindner, Michael , et al. (2017) In European Respiratory Journal 50. p.1-15

Contribution to journal › Article

LSC - 2017 - Hippo-YAP/TAZ signaling is deranged in IPF Wagner, Darcy ^LU

; Alsafadi, Hani ^LU

; Mutze, Kathrin ; Costa, Rita ; Stein, Marlene ; Schiller, Herbert ; Kaminski, Naftali and Koenigshoff, Melanie (2017) In European Respiratory Journal 50(Suppl. 61).

Contribution to journal › Published meeting abstract

An Official American Thoracic Society Workshop Report 2015. Stem Cells and Cell Therapies in Lung Biology and Diseases Wagner, Darcy E ^LU

; Cardoso, Wellington V ; Gilpin, Sarah E ; Majka, Susan ; Ott, Harald ; Randell, Scott H ; Thébaud, Bernard ; Waddell, Thomas and Weiss, Daniel J. (2016) Stem Cells and Cell Therapies in Lung Biology and Lung Diseases 2015 In Annals of the American Thoracic Society 13(8). p.78-259

Contribution to journal › Article

Impairment of immunoproteasome function by cigarette smoke and in chronic obstructive pulmonary disease Kammerl, Ilona E. ; Dann, Angela ; Mossina, Alessandra ; Brech, Dorothee ; Lukas, Christina ; Vosyka, Oliver ; Nathan, Petra ; Conlon, Thomas M ; Wagner, Darcy E. ^LU

and Overkleeft, Hermen S. , et al. (2016) In American Journal of Respiratory and Critical Care Medicine 193(11). p.1230-1241

Contribution to journal › Article

CD11b+ and sca-1+ cells exert the main beneficial effects of systemically administered bone marrow-derivedmononuclear cells in a murinemodel of mixed Th2/Th17 allergic airway inflammation Cruz, Fernanda F. ; Borg, Zachary D. ; Goodwin, Meagan ; Coffey, Amy L. ; Wagner, Darcy E. ^LU

; Rocco, Patricia R. M. and Weiss, Daniel J. (2016) In Stem cells translational medicine 5(4). p.488-499

Contribution to journal › Article

Decreased laminin expression by human lung epithelial cells and fibroblasts cultured in acellular lung scaffolds from aged mice Godin, Lindsay M. ; Sandri, Brian J. ; Wagner, Darcy E. ^LU

; Meyer, Carolyn M. ; Price, Andrew P. ; Akinnola, Ifeolu ; Weiss, Daniel J. and Panoskaltsis-Mortari, Angela Panoskaltsis Mortari (2016) In PLoS ONE 11(3).

Contribution to journal › Article

The global emergence of unregulated stem cell treatments for respiratory diseases : Professional societies need to act Ikonomou, Laertis ; Freishtat, Robert J. ; Wagner, Darcy E. ^LU

; Panoskaltsis-Mortari, Angela and Weiss, Daniel J. (2016) In Annals of the American Thoracic Society 13(8). p.1205-1207

Contribution to journal › Debate/Note/Editorial

Comparative Decellularization and Recellularization of Wild-Type and Alpha 1,3 Galactosyltransferase Knockout Pig Lungs : A Model for Ex Vivo Xenogeneic Lung Bioengineering and Transplantation Platz, Joseph ; Bonenfant, Nicholas R. ; Uhl, Franziska E. ^LU ; Coffey, Amy L. ; McKnight, Tristan ; Parsons, Charles ; Sokocevic, Dino ; Borg, Zachary D. ; Lam, Ying Wai and Deng, Bin , et al. (2016) In Tissue Engineering - Part C: Methods 22(8). p.725-739

Contribution to journal › Article

A Computational Model of Cellular Engraftment on Lung Scaffolds Pothen, Joshua J. ; Rajendran, Vignesh ; Wagner, Darcy ^LU

; Weiss, Daniel J. ; Smith, Bradford J. ; Ma, Baoshun and Bates, Jason H T (2016) In BioResearch Open Access 5(1). p.308-319

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WISP1 mediates IL-6-dependent proliferation in primary human lung fibroblasts Klee, S. ; Lehmann, Maike ; Wagner, D. E. ^LU

; Baarsma, Hoeke A. and Konigshoff, Melanie (2016) In Scientific Reports 6. p.1-11

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Residual Detergent Detection Method for Nondestructive Cytocompatibility Evaluation of Decellularized Whole Lung Scaffolds Zvarova, Barbora ; Uhl, Franziska E. ^LU ; Uriarte, Juan J. ; Borg, Zachary D. ; Coffey, Amy L. ; Bonenfant, Nicholas R. ; Weiss, Daniel J. and Wagner, Darcy E. ^LU

(2016) In Tissue Engineering - Part C: Methods 22(5). p.418-428

Contribution to journal › Article

Linking bronchopulmonary dysplasia to adult chronic lung diseases : role of WNT signaling Ota, Chiharu ; Baarsma, Hoeke A. ; Wagner, Darcy E ^LU

; Hilgendorff, Anne and Königshoff, Melanie (2016) In Molecular and cellular pediatrics 3. p.1-13

Contribution to journal › Scientific review

Freshly thawed and continuously cultured human bone marrow-derived mesenchymal stromal cells comparably ameliorate allergic airways inflammation in immunocompetent mice Cruz, Fernanda F. ; Borg, Zachary D. ; Goodwin, Meagan ; Sokocevic, Dino ; Wagner, Darcy ^LU

; McKenna, David H. ; Rocco, Patricia R. M. and Weiss, Daniel J. (2015) In Stem cells translational medicine 4(6). p.615-624

Contribution to journal › Article

Preclinical validation and imaging of Wnt-induced repair in human 3D lung tissue cultures Uhl, Franziska E. ^LU ; Vierkotten, Sarah ; Wagner, Darcy E. ^LU

; Burgstaller, Gerald ; Costa, Ana Rita ; Koch, Ina ; Lindner, Michael ; Meiners, Silke ; Eickelberg, Oliver and Königshoff, Melanie (2015) In European Respiratory Journal 46(4). p.1150-1166

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An official American Thoracic Society workshop report : Stem cells and cell therapies in lung biology and diseases Weiss, Daniel J. ; Chambers, Daniel ; Giangreco, Adam ; Keating, Armand ; Kotton, Darrell ; Lelkes, Peter I. ; Wagner, Darcy E. ^LU

and Prockop, Darwin J (2015) Stem Cells and Cell Therapies in Lung Biology and Lung Diseases In Annals of the American Thoracic Society 12(4). p.79-97

Contribution to journal › Scientific review

Systemic administration of human bone marrow-derived mesenchymal stromal cell extracellular vesicles ameliorates Aspergillus hyphal extract-induced allergic airway inflammation in immunocompetent mice Cruz, Fernanda F. ; Borg, Zachary D. ; Goodwin, Meagan ; Sokocevic, Dino ; Wagner, Darcy E. ^LU

; Coffey, Amy L. ; Antunes, Mariana ; Robinson, Kristen L. ; Mitsialis, S. Alex and Kourembanas, Stella , et al. (2015) In Stem cells translational medicine 4(11). p.1302-1316

Contribution to journal › Article

Three-dimensional scaffolds of acellular human and porcine lungs for high throughput studies of lung disease and regeneration Wagner, Darcy E. ^LU

; Bonenfant, Nicholas R. ; Sokocevic, Dino ; DeSarno, Michael J ; Borg, Zachary D. ; Parsons, Charles S. ; Brooks, Elice M. ; Platz, Joseph ; Khalpey, Zain I. and Hoganson, David M. , et al. (2014) In Biomaterials 35(9). p.2664-2679

Contribution to journal › Article

Comparative decellularization and recellularization of normal versus emphysematous human lungs Wagner, Darcy E. ^LU

; Bonenfant, Nicholas R. ; Parsons, Charles S. ; Sokocevic, Dino ; Brooks, Elice M. ; Borg, Zachary D. ; Lathrop, Melissa J. ; Wallis, John D. ; Daly, Amanda B. and Lam, Ying Wai , et al. (2014) In Biomaterials 35(10). p.3281-3297

Contribution to journal › Article

Design and synthesis of an artificial pulmonary pleura for high throughput studies in acellular human lungs Wagner, Darcy E. ^LU

; Fenn, Spencer L. ; Bonenfant, Nicholas R. ; Marks, Elliot R. ; Borg, Zachary D. ; Saunders, Patrick ; Oldinski, Rachael A. and Weiss, Daniel J. (2014) In Cellular and Molecular Bioengineering 7(2). p.184-195

Contribution to journal › Article

Tumor-propagating cells and Yap/Taz activity contribute to lung tumor progression and metastasis Lau, Allison N. ; Curtis, Stephen J. ; Fillmore, Christine M. ; Rowbotham, Samuel P. ; Mohseni, Morvarid ; Wagner, Darcy E. ^LU

; Beede, Alexander M. ; Montoro, Daniel T. ; Sinkevicius, Kerstin W. and Walton, Zandra E. , et al. (2014) In EMBO Journal 33(5). p.468-481

Contribution to journal › Article

A microwave-assisted solution combustion synthesis to produce europium-doped calcium phosphate nanowhiskers for bioimaging applications Wagner, Darcy E. ^LU

; Eisenmann, Kathryn M. ; Nestor-Kalinoski, Andrea L. and Bhaduri, Sarit B. (2013) In Acta Biomaterialia 9(9). p.8422-8432

Contribution to journal › Article

The effects of storage and sterilization on de-cellularized and re-cellularized whole lung Bonenfant, Nicholas R. ; Sokocevic, Dino ; Wagner, Darcy E. ^LU

; Borg, Zachary D. ; Lathrop, Melissa J. ; Lam, Ying Wai ; Deng, Bin ; DeSarno, Michael J ; Ashikaga, Taka and Loi, Roberto , et al. (2013) In Biomaterials 34(13). p.3231-3245

Contribution to journal › Article

The effect of age and emphysematous and fibrotic injury on the re-cellularization of de-cellularized lungs Sokocevic, Dino ; Bonenfant, Nicholas R. ; Wagner, Darcy E. ^LU

; Borg, Zachary D. ; Lathrop, Melissa J. ; Lam, Ying Wai ; Deng, Bin ; DeSarno, Michael J ; Ashikaga, Taka and Loi, Roberto , et al. (2013) In Biomaterials 34(13). p.3256-3269

Contribution to journal › Article

Can stem cells be used to generate new lungs? Ex vivo lung bioengineering with decellularized whole lung scaffolds Wagner, Darcy E. ^LU

; Bonvillain, Ryan W. ; Jensen, Todd ; Girard, Eric D. ; Bunnell, Bruce A. ; Finck, Christine M. ; Hoffman, Andrew M. and Weiss, Daniel J. (2013) In Respirology 18(6). p.895-911

Contribution to journal › Scientific review

Microwave-assisted solution combustion synthesis of high aspect ratio calcium phosphate nanoparticles Wagner, Darcy E. ^LU

; Lawrence, Joseph and Bhaduri, Sarit B. (2013) In Journal of Materials Research 28(22). p.3119-3129

Contribution to journal › Article

Cytocompatibility evaluation of microwave sintered biphasic calcium phosphate scaffolds synthesized using pH control Wagner, Darcy E. ^LU

; Jones, Andrew D. ; Zhou, Huan and Bhaduri, Sarit B. (2013) In Materials Science and Engineering C 33(3). p.1710-1719

Contribution to journal › Article

Progress and outlook of inorganic nanoparticles for delivery of nucleic acid sequences related to orthopedic pathologies : A review Wagner, Darcy E. ^LU

and Bhaduri, Sarit B. (2012) In Tissue Engineering - Part B: Reviews 18(1). p.1-14

Contribution to journal › Scientific review

Heat transfer in laminar flows of extended modified power law fluids in rectangular ducts Capobianchi, Massimo and Wagner, Darcy ^LU

(2010) In International Journal of Heat and Mass Transfer 53(1-3). p.558-563

Contribution to journal › Article