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- 2024
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Mark
Nucleotide binding to the ATP-cone in anaerobic ribonucleotide reductases allosterically regulates activity by modulating substrate binding
(
- Contribution to journal › Article
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Mark
Interplay of halogen bonding and solvation in protein-ligand binding
(
- Contribution to journal › Article
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Mark
Structure-guided engineering of immunotherapies targeting TRBC1 and TRBC2 in T cell malignancies
(
- Contribution to journal › Article
- 2023
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Mark
Ligand Sulfur Oxidation State Progressively Alters Galectin-3-Ligand Complex Conformations To Induce Affinity-Influencing Hydrogen Bonds
(
- Contribution to journal › Article
- 2022
-
Mark
Dusquetide modulates innate immune response through binding to p62
(
- Contribution to journal › Article
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Mark
A nucleotide-sensing oligomerization mechanism that controls NrdR-dependent transcription of ribonucleotide reductases
(
- Contribution to journal › Article
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Mark
The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis
(
- Contribution to journal › Article
-
Mark
Structures of activin ligand traps using natural sets of type I and type II TGFβ receptors
(
- Contribution to journal › Article
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Mark
Structural basis of activation and antagonism of receptor signaling mediated by interleukin-27
(
- Contribution to journal › Article
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Mark
The engineered CD80 variant fusion therapeutic davoceticept combines checkpoint antagonism with conditional CD28 costimulation for anti-tumor immunity
(
- Contribution to journal › Article
- 2021
-
Mark
Exploring ligand dynamics in protein crystal structures with ensemble refinement
(
- Contribution to journal › Article
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Mark
Solution Structure of the dATP-Inactivated Class I Ribonucleotide Reductase From Leeuwenhoekiella blandensis by SAXS and Cryo-Electron Microscopy
(
- Contribution to journal › Article
-
Mark
DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously
(
- Contribution to journal › Article
-
Mark
Entropy–Entropy Compensation between the Protein, Ligand, and Solvent Degrees of Freedom Fine-Tunes Affinity in Ligand Binding to Galectin-3C
(
- Contribution to journal › Article
-
Mark
NAD+ pool depletion as a signal for the Rex regulon involved in Streptococcus agalactiae virulence
(
- Contribution to journal › Article
- 2020
-
Mark
Interactive model building in neutron macromolecular crystallography
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Exposing the distinctive modular behavior of β-strands and α-helices in folded proteins
2020) In Proceedings of the National Academy of Sciences of the United States of America 117(46). p.28775-28783(
- Contribution to journal › Article
-
Mark
FragMAX : the fragment-screening platform at the MAX IV Laboratory
(
- Contribution to journal › Article
-
Mark
Current status and future opportunities for serial crystallography at MAX IV Laboratory
(
- Contribution to journal › Article
- 2019
-
Mark
Hunting down hydrogen : Applying neutron macromolecular crystallography to galectins
(
- Contribution to journal › Article
-
Mark
Refinement of protein structures using a combination of quantum-mechanical calculations with neutron and X-ray crystallographic data
(
- Contribution to journal › Article
-
Mark
Are crystallographic : B-factors suitable for calculating protein conformational entropy?
(
- Contribution to journal › Article
-
Mark
Structural Basis for YjbH Adaptor-Mediated Recognition of Transcription Factor Spx
(
- Contribution to journal › Article
-
Mark
A surface-exposed GH26 -mannanase from Bacteroides ovatus : Structure, role, and phylogenetic analysis of BoMan26B
(
- Contribution to journal › Article
-
Mark
Substituted polyfluoroaryl interactions with an arginine side chain in galectin-3 are governed by steric-, desolvation and electronic conjugation effects
(
- Contribution to journal › Article
-
Mark
Redox-induced structural changes in the di-iron and di-manganese forms of Bacillus anthracis ribonucleotide reductase subunit NrdF suggest a mechanism for gating of radical access
(
- Contribution to journal › Article
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Mark
Insight into the dimer dissociation process of the Chromobacterium violaceum (S)-selective amine transaminase
(
- Contribution to journal › Article
-
Mark
3-Substituted 1-Naphthamidomethyl-C-galactosyls Interact with Two Unique Sub-Sites for High-Affinity and High-Selectivity Inhibition of Galectin-3
(
- Contribution to journal › Article
-
Mark
Structure and Energetics of Ligand–Fluorine Interactions with Galectin-3 Backbone and Side-Chain Amides : Insight into Solvation Effects and Multipolar Interactions
(
- Contribution to journal › Article
-
Mark
Class Id ribonucleotide reductase utilizes a Mn2(IV,III) cofactor and undergoes large conformational changes on metal loading
(
- Contribution to journal › Article
-
Mark
Structure-based design and in vivo anti-arthritic activity evaluation of a potent dipeptidyl cyclopropyl nitrile inhibitor of cathepsin C
(
- Contribution to journal › Article
-
Mark
Discovery of three novel sesquiterpene synthases from Streptomyces chartreusis NRRL 3882 and crystal structure of an α-eudesmol synthase
(
- Contribution to journal › Article
-
Mark
Interplay between Conformational Entropy and Solvation Entropy in Protein-Ligand Binding
(
- Contribution to journal › Article
-
Mark
MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM
2019) In Proceedings of the National Academy of Sciences of the United States of America 116(15). p.7533-7542(
- Contribution to journal › Article
- 2018
-
Mark
Structural and Biophysical Characterization of Human EXTL3 : Domain Organization, Glycosylation, and Solution Structure
(
- Contribution to journal › Article
-
Mark
The Cost of Long Catalytic Loops in Folding and Stability of the ALS-Associated Protein SOD1
(
- Contribution to journal › Article
-
Mark
Transaminase-Catalyzed Racemization with Potential for Dynamic Kinetic Resolutions
(
- Contribution to journal › Article
-
Mark
Monosaccharide Derivatives with Low-Nanomolar Lectin Affinity and High Selectivity Based on Combined Fluorine-Amide, Phenyl-Arginine, Sulfur-π, and Halogen Bond Interactions
(
- Contribution to journal › Article
-
Mark
Elucidation of Hydrogen Bonding Patterns in Ligand-Free, Lactose- and Glycerol-Bound Galectin-3C by Neutron Crystallography to Guide Drug Design
(
- Contribution to journal › Article
-
Mark
Systematic Tuning of Fluoro-galectin-3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity
(
- Contribution to journal › Article
-
Mark
Novel ATP-cone-driven allosteric regulation of ribonucleotide reductase via the radical-generating subunit
(
- Contribution to journal › Article
-
Mark
Synthesis of branched and linear 1,4-linked galactan oligosaccharides
(
- Contribution to journal › Article
- 2017
-
Mark
Crystal structure of human chondroadherin : Solving a difficult molecular-replacement problem using de novo models
(
- Contribution to journal › Article
-
Mark
Three-dimensional structures and functional studies of two GH43 arabinofuranosidases from Weissella sp. strain 142 and Lactobacillus brevis
(
- Contribution to journal › Article
-
Mark
Crystal structure of β-glucosidase 1A from Thermotoga neapolitana and comparison of active site mutants for hydrolysis of flavonoid glucosides
(
- Contribution to journal › Article
-
Mark
Galactomannan catabolism conferred by a polysaccharide utilisation locus of Bacteroides ovatus : enzyme synergy and crystal structure of a β-mannanase
(
- Contribution to journal › Article
- 2016
-
Mark
Tricking a Protein To Swap Strands
(
- Contribution to journal › Article
-
Mark
A de Novo Designed Coiled-Coil Peptide with a Reversible pH-Induced Oligomerization Switch
(
- Contribution to journal › Article
-
Mark
Structural Mechanism of Allosteric Activity Regulation in a Ribonucleotide Reductase with Double ATP Cones
(
- Contribution to journal › Article
-
Mark
Cancer differentiating agent hexamethylene bisacetamide inhibits BET bromodomain proteins
(
- Contribution to journal › Article
-
Mark
Perdeuteration, crystallization, data collection and comparison of five neutron diffraction data sets of complexes of human galectin-3C
(
- Contribution to journal › Article
-
Mark
Context matters : The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies
(
- Contribution to journal › Article
- 2015
-
Mark
The origin and evolution of ribonucleotide reduction.
(
- Contribution to journal › Scientific review
-
Mark
Neutron Crystallographic Studies Reveal Hydrogen Bond and Water-Mediated Interactions between a Carbohydrate-Binding Module and Its Bound Carbohydrate Ligand.
(
- Contribution to journal › Article
-
Mark
Structural aspects of N-glycosylations and the C-terminal region in human glypican-1.
(
- Contribution to journal › Article
-
Mark
Crystallization, neutron data collection, initial structure refinement and analysis of a xyloglucan heptamer bound to an engineered carbohydrate-binding module from xylanase.
(
- Contribution to journal › Article
-
Mark
The Crystal Structure of Thermotoga maritima Class III Ribonucleotide Reductase Lacks a Radical Cysteine Pre-Positioned in the Active Site
(
- Contribution to journal › Article
-
Mark
Thermodynamics of protein destabilization in live cells.
(
- Contribution to journal › Article
-
Mark
Structure-function analysis of Heterodimer Formation, oligomerization, and receptor binding of the staphylococcus aureus bi-component toxin LukGH
(
- Contribution to journal › Article
-
Mark
Status of the crystallography beamlines at the MAX IV Laboratory
(
- Contribution to journal › Scientific review
- 2014
-
Mark
GPC1 (glypican 1)
(
- Contribution to journal › Article
-
Mark
Polar interactions with branching xyloses and CH-π interactions define carbohydrate binding module recognition of xyloglucan
(
- Contribution to journal › Article
-
Mark
An Aspergillus nidulans β-mannanase with high transglycosylation capacity revealed through comparative studies within glycosidase family 5.
(
- Contribution to journal › Article
- 2013
-
Mark
GPC1 (glypican 1) : Atlas of Genetics and Cytogenetics in Oncology and Haematology
2013)(
- Non-textual form › Dataset
-
Mark
Improvements in the order, isotropy and electron density of glypican-1 crystals by controlled dehydration.
(
- Contribution to journal › Article
-
Mark
The macromolecular crystallography beamline I911-3 at the MAX IV laboratory.
(
- Contribution to journal › Article
-
Mark
Global structural motions from the strain of a single hydrogen bond
(
- Contribution to journal › Article
-
Mark
BioMAX: The Future Macromolecular Crystallography Beamline at MAX IV
(
- Chapter in Book/Report/Conference proceeding › Paper in conference proceeding
- 2012
-
Mark
DNA building blocks: keeping control of manufacture
(
- Contribution to journal › Scientific review
-
Mark
Crystal structure of N-glycosylated human glypican-1 core protein: Structure of two loops evolutionarily conserved in vertebrate glypican-1.
(
- Contribution to journal › Article
-
Mark
Trimming Down a Protein Structure to Its Bare Foldons SPATIAL ORGANIZATION OF THE COOPERATIVE UNIT
(
- Contribution to journal › Article
-
Mark
Structural basis for carbohydrate binding specificity - a comparative assessment of two engineered carbohydrate binding modules.
(
- Contribution to journal › Article
-
Mark
DETAILED STRUCTURAL INFORMATION OF SPECIFICITY DETERMINING INTERACTIONS IN ENGINEERED CARBOHYDRATE BINDING MODULES
2012) 26th International Carbohydrate Symposium(
- Contribution to conference › Abstract
-
Mark
Crystal structures of the Chromobacterium violaceumω-transaminase reveal major structural rearrangements upon binding of coenzyme PLP.
(
- Contribution to journal › Article
-
Mark
The Carbohydrate-Binding Site in Galectin-3 Is Preorganized To Recognize a Sugarlike Framework of Oxygens: Ultra-High-Resolution Structures and Water Dynamics
(
- Contribution to journal › Article
- 2011
-
Mark
Closing the circle on ribonucleotide reductases
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Implications of the Inability of Listeria monocytogenes EGD-e To Grow Anaerobically Due to a Deletion in the Class III NrdD Ribonucleotide Reductase for Its Use as a Model Laboratory Strain
(
- Contribution to journal › Article
-
Mark
Small-angle X-ray Scattering Study of a Rex Family Repressor: Conformational Response to NADH and NAD(+) Binding in Solution.
(
- Contribution to journal › Article
- 2010
-
Mark
Structural Basis for Adenosylcobalamin Activation in AdoCbl-Dependent Ribonucleotide Reductases
(
- Contribution to journal › Article
-
Mark
Folding Catalysis by Transient Coordination of Zn2+ to the Cu Ligands of the ALS-Associated Enzyme Cu/Zn Superoxide Dismutase 1
(
- Contribution to journal › Article
-
Mark
Structural and Functional Analyses of beta-Glucosidase 3B from Thermotoga neapolitana: A Thermostable Three-Domain Representative of Glycoside Hydrolase 3.
(
- Contribution to journal › Article
-
Mark
Non-specific CBM4-2 variant X-2 L110F – apo, xylopentaose, cellopentaose structures.
2010) p.338-339(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
High-resolution crystal structures of the flavoprotein NrdI in oxidized and reduced states - an unusual flavodoxin: Structural biology.
(
- Contribution to journal › Article
- 2009
-
Mark
Phosphorylation of hormone-sensitive lipase by protein kinase A in vitro promotes an increase in its hydrophobic surface area.
(
- Contribution to journal › Article
-
Mark
Functional features cause misfolding of the ALS-provoking enzyme SOD1
(
- Contribution to journal › Article
- 2008
-
Mark
Structure and functional properties of the Bacillus subtilis transcriptional repressor Rex.
(
- Contribution to journal › Article
-
Mark
Ser649 and Ser650 are the major determinants of protein kinase A-mediated activation of human hormone-sensitive lipase against lipid substrates.
(
- Contribution to journal › Article
-
Mark
Purification, crystallization and preliminary X-ray diffraction analysis of human chondroadherin.
2008) In Acta Crystallographica. Section F: Structural Biology and Crystallization Communications 64(Pt 6). p.516-519(
- Contribution to journal › Article
-
Mark
Engineered CBM4-2 variant X-2 – apo, xylotetrose, xylopentose structures.
2008) p.368-369(
- Chapter in Book/Report/Conference proceeding › Book chapter
- 2007
-
Mark
The coupling between disulphide status, metallation and dimer interface strength in Cu/Zn superoxide dismutase
(
- Contribution to journal › Article
-
Mark
Folding of S6 structures with divergent amino acid composition: Pathway flexibility within partly overlapping foldons
(
- Contribution to journal › Article
-
Mark
Expression, purification, crystallisation and preliminary X-ray diffraction analysis of Thermotoga neapolitana beta-glucosidase B
2007) In Acta Crystallographica. Section F: Structural Biology and Crystallization Communications 63(9). p.802-806(
- Contribution to journal › Article
- 2005
-
Mark
Modern mRNA proofreading and repair: Clues that the Last Universal Common Ancestor possessed an RNA genome?
(
- Contribution to journal › Scientific review
-
Mark
Structural insights into fusidic acid resistance and sensitivity in EF-G
(
- Contribution to journal › Article
-
Mark
Crystal structure of a mutant elongation factor G trapped with a GTP analogue
(
- Contribution to journal › Article
-
Mark
A new tyrosyl radical on Phe(208) as ligand to the diiron center in Escherichia coli ribonucleotide reductase, mutant R2-Y122H - Combined X-ray diffraction and EPR/ENDOR studies
(
- Contribution to journal › Article
- 2004
-
Mark
Structural basis for interactions between tenascins and lectican C-type lectin domains: evidence for a crosslinking role for tenascins.
(
- Contribution to journal › Article
-
Mark
Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase
(
- Contribution to journal › Article
-
Mark
The new macromolecular crystallography stations at MAX-lab: The MAD station
(
- Chapter in Book/Report/Conference proceeding › Paper in conference proceeding
- 2003
-
Mark
A metal binding site in the catalytic subunit of anaerobic ribonucleotide reductase.
(
- Contribution to journal › Article