Division of Molecular Medicine and Gene Therapy
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- 2021
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Activation of endogenous retroviruses during brain development causes an inflammatory response
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- Contribution to journal › Article
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Decreased PGC1beta expression results in disrupted human erythroid differentiation, impaired hemoglobinization and cell cycle exit
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- Contribution to journal › Article
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Elucidating regulators of red blood cell development in health and disease
2021) In Lund University, Faculty of Medicine Doctoral Dissertation Series(
- Thesis › Doctoral thesis (compilation)
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Human Primary Airway Basal Cells Display a Continuum of Molecular Phases from Health to Disease in Chronic Obstructive Pulmonary Disease
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- Contribution to journal › Article
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Hypoxia-induced alpha-globin expression in syncytiotrophoblasts mimics the pattern observed in preeclamptic placentas
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- Contribution to journal › Article
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Ontogenic shifts in cellular fate are linked to proteotype changes in lineage-biased hematopoietic progenitor cells
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- Contribution to journal › Article
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Sister chromatid cohesion defects are associated with chromosomal copy number heterogeneity in high hyperdiploid childhood acute lymphoblastic leukemia
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- Contribution to journal › Article
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Cell Fate Reprogramming in the Era of Cancer Immunotherapy
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- Contribution to journal › Scientific review
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Yippee like 4 (Ypel4) is essential for normal mouse red blood cell membrane integrity
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- Contribution to journal › Article
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Reprogramming Stars #2 : Reprogramming towards Neural Lineages - An Interview with Dr. Henrik Ahlenius
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- Contribution to journal › Debate/Note/Editorial
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The active component of ginseng, ginsenoside Rb1, improves erythropoiesis in models of Diamond–Blackfan anemia by targeting Nemo-like kinase
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- Contribution to journal › Article
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Combinatorial molecule screening identifies a novel diterpene and the BET inhibitor CPI-203 as differentiation inducers of primary acute myeloid leukemia cells
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- Contribution to journal › Article
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Mitochondrial Potentiation Ameliorates Age-Related Heterogeneity in Hematopoietic Stem Cell Function
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- Contribution to journal › Article
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Uncoupling key determinants of hematopoietic stem cell engraftment through cell-specific and temporally controlled recipient conditioning
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- Contribution to journal › Article
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Bone marrow transplantation without myeloablative conditioning in a mouse model for Diamond-Blackfan anemia corrects the disease phenotype
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- Contribution to journal › Article
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BCAT1 decreases the sensitivity of cancer cells to cisplatin by regulating mTOR-mediated autophagy via branched-chain amino acid metabolism
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- Contribution to journal › Article
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Glutamine metabolism regulates endothelial to hematopoietic transition and hematopoietic lineage specification
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- Contribution to journal › Article
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Restoring the immunogenicity of cancer cells with dendritic cell reprogramming
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- Contribution to journal › Published meeting abstract
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GATA2 at the mitosis-to-G1 transition is critical for definitive hematopoiesis
2021) 2021 Virtual Annual Scientific Meeting of the ISEH - International Society for Experimental Hematology: ISEH 50th Annual Meeting In Experimental Hematology 100(Suppl). p.35-35(
- Contribution to journal › Published meeting abstract
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Organ sparing total marrow irradiation compared to total body irradiation prior to allogeneic stem cell transplantation
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- Contribution to journal › Article
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In vitro differentiation of human pluripotent stem cells into the B lineage using OP9-MS5 co-culture
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- Contribution to journal › Article
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Genome-wide association study on 13,167 individuals identifies regulators of hematopoietic stem and progenitor cell levels in human blood
2021)(
- Working paper/Preprint › Preprint in preprint archive
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Reprogramming Stars #4 : A Reprogramming Approach for Parkinson's Disease-An Interview with Dr. Malin Parmar
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- Contribution to journal › Debate/Note/Editorial
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Reprogramming Stars #3 : Mechanisms of iPSC Reprogramming-An Interview with Dr. Keisuke Kaji
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- Contribution to journal › Debate/Note/Editorial
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Compositions for reprogramming into dendritic cells type 2 competent for antigen presentation, methods and uses thereof
2021) WO2021105234(
- Patent › Patent
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Compositions for reprogramming cells into plasmacytoid dendritic cells or interferon producing cells, methods and uses thereof
2021) WO2021069672(
- Patent › Patent
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BMP signaling is required for postnatal murine hematopoietic stem cell self-renewal
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- Contribution to journal › Article
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Stem cell aging and wound healing
2021) p.53-60(
- Chapter in Book/Report/Conference proceeding › Book chapter
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Generating Dendritic Cells by Direct Cell Reprogramming. Merging cellular reprogramming with immunology towards the development of novel cancer immunotherapies.
2021) In Lund University, Faculty of Medicine Doctoral Dissertation Series(
- Thesis › Doctoral thesis (compilation)
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Mark
The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition
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- Contribution to journal › Article
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Reprogramming Stars #1 : Genome Programming through the Cell Cycle - An Interview with Dr. Tomomi Tsubouchi
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- Contribution to journal › Debate/Note/Editorial
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Reprogramming, the Journal
(
- Contribution to journal › Debate/Note/Editorial
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Disruption of a GATA2-TAL1-ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells
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- Contribution to journal › Article
- 2020
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A SOX2 reporter system identifies gastric cancer stem-like cells sensitive to monensin
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- Contribution to journal › Article
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European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia
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- Contribution to journal › Scientific review
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Early growth response 1 regulates hematopoietic support and proliferation in human primary bone marrow stromal cells
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- Contribution to journal › Article
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Lysine-specific demethylase 1A (LSD1) restricts ex vivo propagation of human HSCs and is a target of UM171
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- Contribution to journal › Article
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Enhancing mitochondrial function in vivo rescues MDS-like anemia induced by pRb deficiency
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- Contribution to journal › Article
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Efficient and nontoxic biomolecule delivery to primary human hematopoietic stem cells using nanostraws
2020) In Proceedings of the National Academy of Sciences of the United States of America 117(35). p.21267-21273(
- Contribution to journal › Article
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Calmodulin inhibitors improve erythropoiesis in Diamond-Blackfan anemia
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- Contribution to journal › Article
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The Role of α1-Microglobulin (A1M) in Erythropoiesis and Erythrocyte Homeostasis-Therapeutic Opportunities in Hemolytic Conditions
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- Contribution to journal › Scientific review
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Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Disease 2019
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- Contribution to journal › Scientific review
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Identification of regulators of hematopoietic stem and progenitor cells in vivo in humans using population genetics
2020) European Human Genetics Virtual Conference(
- Contribution to conference › Abstract
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Så skapar nanoteknik nya vägar till stamcellers inre
2020) In Onkologi i Sverige : den oberoende tidningen för svensk cancervård(
- Contribution to specialist publication or newspaper › Specialist publication article
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Transcriptome sequencing identifies a noncoding, deep intronic variant in CLCN7 causing autosomal recessive osteopetrosis
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- Contribution to journal › Article
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Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase
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- Contribution to journal › Article
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Generation of gene-corrected functional osteoclasts from osteopetrotic induced pluripotent stem cells
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- Contribution to journal › Article
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Induction of blood-circulating bile acids supports recovery from myelosuppressive chemotherapy
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- Contribution to journal › Article
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S100A6 is a critical regulator of hematopoietic stem cells.
2020) In Leukemia(
- Contribution to journal › Article
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CXCR4 Signaling Has a CXCL12-Independent Essential Role in Murine MLL-AF9-Driven Acute Myeloid Leukemia
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- Contribution to journal › Article
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Mononuclear phagocyte regulation by the transcription factor Blimp-1 in health and disease
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- Contribution to journal › Scientific review
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Metformin-induced suppression of Nemo-like kinase improves erythropoiesis in preclinical models of Diamond–Blackfan anemia through induction of miR-26a
(
- Contribution to journal › Article
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Combined lentiviral- and RNA-mediated CRISPR/Cas9 delivery for efficient and traceable gene editing in human hematopoietic stem and progenitor cells
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- Contribution to journal › Article
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Prospective isolation of radiation induced erythroid stress progenitors reveals unique transcriptomic and epigenetic signatures enabling increased erythroid output
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- Contribution to journal › Article
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Gene editing of CD34+ progenitor cells from single blood donor waste bags to create cultured early erythroid cells for study of blood group knock-outs
2020) The 36th International ISBT Congress, Virtual meeting In Vox Sanguinis 115(Suppl. s1). p.363-363(
- Contribution to journal › Published meeting abstract
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Mark
Direct Reprogramming of Mouse Embryonic Fibroblasts to Conventional Type 1 Dendritic Cells by Enforced Expression of Transcription Factors
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- Contribution to journal › Article
- 2019
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Protein biomarkers associated with pain mechanisms in osteoarthritis
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- Contribution to journal › Article
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The effect of 2D and 3D cell cultures on treatment response, EMT profile and stem cell features in head and neck cancer 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis
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- Contribution to journal › Article
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A dual amylin and calcitonin receptor agonist inhibits pain behavior and reduces cartilage pathology in an osteoarthritis rat model
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- Contribution to journal › Article
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Ex Vivo Expansion of Human Hematopoietic Stem Cells
(
- Thesis › Doctoral thesis (compilation)
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Improved survival prognostication of node-positive malignant melanoma patients utilizing shotgun proteomics guided by histopathological characterization and genomic data
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- Contribution to journal › Article
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HMGA2 promotes long-term engraftment and myeloerythroid differentiation of human hematopoietic stem and progenitor cells
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- Contribution to journal › Article
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MiR-378a suppresses tenogenic differentiation and tendon repair by targeting at TGF-β2
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- Contribution to journal › Article
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Cyclin-dependent kinase 8/19 inhibition suppresses osteoclastogenesis by downregulating RANK and promotes osteoblast mineralization and cancellous bone healing
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- Contribution to journal › Article
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Combining naproxen and a dual amylin and calcitonin receptor agonist improves pain and structural outcomes in the collagen-induced arthritis rat model
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- Contribution to journal › Article
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GPDPLQ1237—A Type II Collagen Neo-Epitope Biomarker of Osteoclast- and Inflammation-Derived Cartilage Degradation in vitro
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- Contribution to journal › Article
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A Phenotypic Screening Assay Identifies Modulators of Diamond Blackfan Anemia
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- Contribution to journal › Article
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Endothelial protein C receptor (EPCR) expression marks human fetal liver hematopoietic stem cells
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- Contribution to journal › Article
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Preeclampsia is Associated with Sex-Specific Transcriptional and Proteomic Changes in Fetal Erythroid Cells
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- Contribution to journal › Article
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Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells
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- Contribution to journal › Article
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Junctional Adhesion Molecule 2 Represents a Subset of Hematopoietic Stem Cells with Enhanced Potential for T Lymphopoiesis
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- Contribution to journal › Article
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Genome-wide mapping of bivalent histone modifications in hepatic stem/progenitor cells
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- Contribution to journal › Article
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Hematopoietic stem cell-targeted neonatal gene therapy with a clinically applicable lentiviral vector corrects osteopetrosis in oc/oc Mice
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- Contribution to journal › Article
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Is immunotherapy the holy grail for pancreatic cancer?
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- Contribution to journal › Debate/Note/Editorial
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Understanding and Modulating Immunity With Cell Reprogramming
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- Contribution to journal › Scientific review
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The hidden story of heterogeneous B-raf V600E mutation quantitative protein expression in metastatic melanoma—association with clinical outcome and tumor phenotypes
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- Contribution to journal › Article
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Induction of human hemogenesis in adult fibroblasts by defined factors and hematopoietic coculture
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- Contribution to journal › Article
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Hemogenic Reprogramming of Human Fibroblasts by Enforced Expression of Transcription Factors
2019) In Journal of visualized experiments : JoVE(
- Contribution to journal › Article
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Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors
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- Contribution to journal › Article
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Autoantibodies in Pandemrix®-induced narcolepsy : Nine candidate autoantigens fail the conformational autoantibody test
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- Contribution to journal › Article
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The Role of Intracellular Calcium Signaling in Hematopoietic Stem Cells
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- Contribution to journal › Scientific review
- 2018
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In vitro tumorigenic assay : colony forming assay for cancer stem cells
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- Chapter in Book/Report/Conference proceeding › Book chapter
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Interleukin 4 induces apoptosis of acute myeloid leukemia cells in a Stat6 dependent manner
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- Contribution to journal › Article
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Programming Blood Cell Fates. Insights from Direct Lineage Conversion and Development
2018)(
- Thesis › Doctoral thesis (compilation)
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Mark
Regulation of unfolded protein response in hematopoietic stem cells
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- Contribution to journal › Article
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A new genetic tool to improve immune-compromised mouse models : Derivation and CRISPR/Cas9-mediated targeting of NRG embryonic stem cell lines
(
- Contribution to journal › Article
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Pentaisomaltose, an Alternative to DMSO. Engraftment of Cryopreserved Human CD34+ Cells in Immunodeficient NSG Mice
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- Contribution to journal › Article
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Transient inhibition of NF-κB signaling enhances ex vivo propagation of human hematopoietic stem cells
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- Contribution to journal › Article
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Direct role of FLT3 in regulation of early lymphoid progenitors
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- Contribution to journal › Article
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On new and current treatments for Diamond-Blackfan anemia
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- Thesis › Doctoral thesis (compilation)
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Cooperative Transcription Factor Induction Mediates Hemogenic Reprogramming
2018) In Cell Reports(
- Contribution to journal › Article
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Osteoclasts degrade bone and cartilage knee joint compartments through different resorption processes
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- Contribution to journal › Article
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Targeting NSG Mice Engrafting Cells with a Clinically Applicable Lentiviral Vector Corrects Osteoclasts in Infantile Malignant Osteopetrosis
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- Contribution to journal › Article
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Development of Novel Therapies, Models, and Biomarkers for Osteoclast-Related Diseases
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- Thesis › Doctoral thesis (compilation)
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Mark
Cohesin in haematopoiesis and leukaemia
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- Contribution to journal › Scientific review
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Tipping clonal hematopoiesis into transformation
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- Contribution to journal › Debate/Note/Editorial
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Prospective evaluation of a combination of fungal biomarkers for the diagnosis of invasive fungal disease in high-risk haematology patients
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- Contribution to journal › Article
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Identification of intrinsic regulators in normal and malignant human hematopoiesis. An RNA-interference approach.
(
- Thesis › Doctoral thesis (compilation)
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Mark
Fetal gene therapy for neurodegenerative disease of infants
(
- Contribution to journal › Letter
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Mark
The Role of Hepatic Leukemia Factor in Hematopoiesis
2018)(
- Thesis › Doctoral thesis (compilation)