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- 2024
-
Mark
A temporal developmental map separates human NK cells from noncytotoxic ILCs through clonal and single-cell analysis
(
- Contribution to journal › Article
-
Mark
Ontogeny shapes the ability of ETV6::RUNX1 to enhance hematopoietic stem cell self-renewal and disrupt early lymphopoiesis
(
- Contribution to journal › Letter
-
Mark
A complex interplay of intra- and extracellular factors regulates the outcome of fetal- and adult-derived MLL-rearranged leukemia
2024) In Leukemia(
- Contribution to journal › Article
-
Mark
Implications of stress-induced gene expression for hematopoietic stem cell aging studies
2024) In Nature Aging(
- Contribution to journal › Article
-
Mark
LIN28B promotes differentiation of fully transformed AML cells but is dispensable for fetal leukemia suppression
(
- Contribution to journal › Letter
- 2023
-
Mark
Temporal dynamics of TNF-mediated changes in hematopoietic stem cell function and recovery
(
- Contribution to journal › Article
-
Mark
Temporal multimodal single-cell profiling of native hematopoiesis illuminates altered differentiation trajectories with age
(
- Contribution to journal › Article
-
Mark
A fetal tumor suppressor axis abrogates MLL-fusion-driven acute myeloid leukemia
(
- Contribution to journal › Article
- 2022
-
Mark
A self-sustaining layer of early-life-origin B cells drives steady-state IgA responses in the adult gut
(
- Contribution to journal › Article
-
Mark
Bmi1 induction protects hematopoietic stem cells against pronounced long-term hematopoietic stress
(
- Contribution to journal › Article
-
Mark
Developmental cues license megakaryocyte priming in murine hematopoietic stem cells
(
- Contribution to journal › Article
-
Mark
Concurrent stem- and lineage-affiliated chromatin programs precede hematopoietic lineage restriction
(
- Contribution to journal › Article
-
Mark
A somatic mutation in moesin drives progression into acute myeloid leukemia
(
- Contribution to journal › Article
-
Mark
Antigen-Presenting B Cells Program the Efferent Lymph T Helper Cell Response
(
- Contribution to journal › Article
-
Mark
Stem Cells, Hematopoiesis and Lineage Tracing : Transplantation-Centric Views and Beyond
(
- Contribution to journal › Scientific review
- 2021
-
Mark
Reconciling Flux Experiments for Quantitative Modeling of Normal and Malignant Hematopoietic Stem/Progenitor Dynamics
(
- Contribution to journal › Article
- 2020
-
Mark
Enhancing Hematopoiesis from Murine Embryonic Stem Cells through MLL1-Induced Activation of a Rac/Rho/Integrin Signaling Axis
(
- Contribution to journal › Article
-
Mark
Continuous mitotic activity of primitive hematopoietic stem cells in adult mice
(
- Contribution to journal › Article
- 2019
-
Mark
Loss of MafA and MafB expression promotes islet inflammation.
(
- Contribution to journal › Article
-
Mark
Hif-1α Deletion May Lead to Adverse Treatment Effect in a Mouse Model of MLL-AF9-Driven AML
(
- Contribution to journal › Article
-
Mark
The efficiency of murine MLL-ENL-driven leukemia initiation changes with age and peaks during neonatal development
(
- Contribution to journal › Article
- 2018
-
Mark
Immunophenotypic identification of early myeloerythroid development
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Immunoediting is not a primary transformation event in a murine model of MLL-ENL AML
(
- Contribution to journal › Article
-
Mark
SAMD9 and SAMD9L in inherited predisposition to ataxia, pancytopenia, and myeloid malignancies
(
- Contribution to journal › Article
-
Mark
Dissection of progenitor compartments resolves developmental trajectories in B-lymphopoiesis
(
- Contribution to journal › Article
-
Mark
Rapid and efficient induction of functional astrocytes from human pluripotent stem cells
(
- Contribution to journal › Article
-
Mark
Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging
(
- Contribution to journal › Article
- 2017
-
Mark
Induction of the 5S RNP–Mdm2–p53 ribosomal stress pathway delays the initiation but fails to eradicate established murine acute myeloid leukemia
(
- Contribution to journal › Article
-
Mark
Clonal reversal of ageing-associated stem cell lineage bias via a pluripotent intermediate
(
- Contribution to journal › Article
-
Mark
MLL-ENL-mediated leukemia initiation at the interface of lymphoid commitment
(
- Contribution to journal › Article
-
Mark
The slippery slope of hematopoietic stem cell aging
(
- Contribution to journal › Article
-
Mark
Critical Modulation of Hematopoietic Lineage Fate by Hepatic Leukemia Factor
(
- Contribution to journal › Article
-
Mark
Molecular mechanisms underlying lineage bias in aging hematopoiesis
(
- Contribution to journal › Scientific review
-
Mark
ZFP521 regulates murine hematopoietic stem cell function and facilitates MLL-AF9 leukemogenesis in mouse and human cells
(
- Contribution to journal › Article
-
Mark
Gain-of-function SAMD9L mutations cause a syndrome of cytopenia, immunodeficiency, MDS and neurological symptoms
(
- Contribution to journal › Article
-
Mark
Hepatic Leukemia Factor Maintains Quiescence of Hematopoietic Stem Cells and Protects the Stem Cell Pool during Regeneration
(
- Contribution to journal › Article
- 2016
-
Mark
Hematopoiesis at single-cell resolution
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Human and murine hematopoietic stem cell aging is associated with functional impairments and intrinsic megakaryocytic/erythroid bias
(
- Contribution to journal › Article
-
Mark
Mitotic History Reveals Distinct Stem Cell Populations and Their Contributions to Hematopoiesis
(
- Contribution to journal › Article
-
Mark
Cellular Barcoding Links B-1a B Cell Potential to a Fetal Hematopoietic Stem Cell State at the Single-Cell Level
(
- Contribution to journal › Article
-
Mark
Potential Pitfalls of the Mx1-Cre System : Implications for Experimental Modeling of Normal and Malignant Hematopoiesis
(
- Contribution to journal › Article
- 2015
-
Mark
SCExV: a webtool for the analysis and visualisation of single cell qRT-PCR data.
(
- Contribution to journal › Article
-
Mark
Concise Review: Hematopoietic Stem Cell Aging and the Prospects for Rejuvenation.
(
- Contribution to journal › Article
-
Mark
Probing hematopoietic stem cell function using serial transplantation: Seeding characteristics and the impact of stem cell purification.
(
- Contribution to journal › Article
-
Mark
Disruption of the 5S RNP-Mdm2 interaction significantly improves the erythroid defect in a mouse model for Diamond-Blackfan anemia.
(
- Contribution to journal › Article
- 2014
-
Mark
Hematopoietic Stem Cells Are Intrinsically Protected against MLL-ENL-Mediated Transformation.
(
- Contribution to journal › Article
-
Mark
Somatic cells with a heavy mitochondrial DNA mutational load render iPS cells with distinct differentiation defects.
(
- Contribution to journal › Article
-
Mark
Efficient Ablation of Genes in Human Hematopoietic Stem and Effector Cells using CRISPR/Cas9.
(
- Contribution to journal › Article
-
Mark
Induced Hematopoietic Stem Cells: Unlocking Restrictions in Lineage Potential and Self-renewal.
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
HIF-1α can act as a tumor suppressor gene in murine Acute Myeloid Leukemia.
(
- Contribution to journal › Article
- 2013
-
Mark
Frequency determination of rare populations by flow cytometry: A hematopoietic stem cell perspective.
(
- Contribution to journal › Scientific review
-
Mark
An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state.
(
- Contribution to journal › Article
-
Mark
Dynamical modelling of haematopoiesis: an integrated view over the system in homeostasis and under perturbation.
(
- Contribution to journal › Article
-
Mark
SOCS2 is dispensable for BCR/ABL1-induced chronic myeloid leukemia-like disease and for normal hematopoietic stem cell function.
(
- Contribution to journal › Article
- 2012
-
Mark
Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia.
(
- Contribution to journal › Article
-
Mark
Reduced repression of cytokine signaling ameliorates age-induced decline in hematopoietic stem cell function.
2012) In Aging Cell(
- Contribution to journal › Article
- 2011
-
Mark
Accumulating mitochondrial DNA mutations drive premature hematopoietic aging phenotypes distinct from physiological stem cell aging.
(
- Contribution to journal › Article
-
Mark
Flow cytometry-based identification of immature myeloerythroid development.
(
- Contribution to journal › Article
-
Mark
Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia.
(
- Contribution to journal › Article
-
Mark
Tumor necrosis factor restricts hematopoietic stem cell activity in mice: involvement of two distinct receptors.
(
- Contribution to journal › Article
-
Mark
The transcription factors E2A and HEB act in concert to induce the expression of FOXO1 in the common lymphoid progenitor
(
- Contribution to journal › Article
- 2010
-
Mark
Chronic RPS19 Deficiency Leads to Bone Marrow Failure In a Mouse Model for Diamond Blackfan Anemia
(
- Contribution to journal › Published meeting abstract
-
Mark
Shaping up a lineage-lessons from B lymphopoesis.
(
- Contribution to journal › Article
-
Mark
Load and lock: the molecular mechanisms of B-lymphocyte commitment.
(
- Contribution to journal › Article
-
Mark
Genomics based analysis of interactions between developing B-lymphocytes and stromal cells reveal complex interactions and two-way communication
(
- Contribution to journal › Article
-
Mark
Single cell analysis of the common lymphoid progenitor compartment reveals functional and molecular heterogeneity.
(
- Contribution to journal › Article
-
Mark
Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion
(
- Contribution to journal › Article
- 2009
-
Mark
Niche recycling through division-independent egress of hematopoietic stem cells
(
- Contribution to journal › Article
-
Mark
Hematopoietic stem cell ageing is uncoupled from p16(INK4A)-mediated senescence.
(
- Contribution to journal › Article
-
Mark
A Novel Mouse Model for RPS19-Deficient Diamond-Blackfan Anemia Locates the Erythroid Defect at CFU-E/Proerythroblast Transition
(
- Contribution to journal › Published meeting abstract
-
Mark
Hematopoietic Stem Cell Expansion Precedes the Generation of Committed Myeloid Leukemia-initiating Cells in C/EBP alpha Mutant AML
(
- Contribution to journal › Article
-
Mark
Niche Recycling through Division-Independent Egress of Hematopoietic Stem Cells.
(
- Contribution to journal › Published meeting abstract
- 2008
-
Mark
NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements
(
- Contribution to journal › Article
-
Mark
EBF1 is essential for B-Lineage priming and establishment of a transcription factor network in common lymphoid progenitors
(
- Contribution to journal › Article
-
Mark
Deciphering developmental stages of adult myelopoiesis.
(
- Contribution to journal › Article
-
Mark
A novel assay to trace proliferation history in vivo reveals that enhanced divisional kinetics accompany loss of hematopoietic stem cell self-renewal.
(
- Contribution to journal › Article
-
Mark
Kit regulates maintenance of quiescent hematopoietic stem cells.
(
- Contribution to journal › Article
-
Mark
B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic progenitor cells
(
- Contribution to journal › Article
- 2007
-
Mark
The CXCL12, periostin and CCL9 genes are direct targets for early B-cell factor (EBF) in OP-9 stroma cells.
(
- Contribution to journal › Article
-
Mark
Hematopoietic stem cell aging: Mechanism and consequence
(
- Contribution to journal › Article
-
Mark
Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy
(
- Contribution to journal › Article
-
Mark
Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging
(
- Contribution to journal › Article
-
Mark
Endoglin is not critical for hematopoietic stem cell engraftment and reconstitution but regulates adult erythroid development
(
- Contribution to journal › Article
-
Mark
Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells
(
- Contribution to journal › Article
-
Mark
Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
(
- Contribution to journal › Article
- 2006
-
Mark
Rapid lymphocyte reconstitution of unconditioned immunodeficient mice with non-self-renewing multipotent hematopoietic progenitors
(
- Contribution to journal › Article
-
Mark
Hematopoietic stem cells: the paradigmatic tissue-specific stem cell
(
- Contribution to journal › Article
-
Mark
Prolonged cell cycle transit is a defining and developmentally conserved hemopoietic stem cell property.
(
- Contribution to journal › Article
-
Mark
Purified hematopoietic stem cell engraftment of rare niches corrects severe lymphoid deficiencies without host conditioning
(
- Contribution to journal › Article
-
Mark
Transcription factor profiling in individual hematopoietic progenitors by digital RT-PCR
(
- Contribution to journal › Article
- 2005
-
Mark
Cell intrinsic alterations underlie hematopoietic stem cell aging
(
- Contribution to journal › Article
-
Mark
Deficiency of oncoretrovirally transduced hematopoietic stem cells and correction through ex vivo expansion.
(
- Contribution to journal › Article
-
Mark
Identification of Lin-Sca1+kit+CD34+Flt3- short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated recipients.
(
- Contribution to journal › Article
-
Mark
Loss of C/EBP alpha cell cycle control increases myeloid progenitor proliferation and transforms the neutrophil granulocyte lineage
(
- Contribution to journal › Article
-
Mark
IFN-{gamma} Negatively Modulates Self-Renewal of Repopulating Human Hemopoietic Stem Cells.
(
- Contribution to journal › Article
-
Mark
Identification of Flt3(+) lympho-myeloid stem cells lacking erythro-megakaryocytic potential: A revised road map for adult blood lineage commitment
(
- Contribution to journal › Article
- 2004
-
Mark
Deceptive multilineage reconstitution analysis of mice transplanted with hemopoietic stem cells, and implications for assessment of stem cell numbers and lineage potentials.
(
- Contribution to journal › Article
- 2003
-
Mark
Human reconstituting hematopoietic stem cells up-regulate Fas expression upon active cell cycling but remain resistant to Fas-induced suppression.
(
- Contribution to journal › Article
-
Mark
Complementary Signaling through flt3 and Interleukin-7 Receptor {alpha} Is Indispensable for Fetal and Adult B Cell Genesis.
(
- Contribution to journal › Article
-
Mark
Molecular regulation of hematopoietic stem cells
2003)(
- Thesis › Doctoral thesis (compilation)