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- 2024
-
Mark
The history and status of dopamine cell therapies for Parkinson's disease
2024) In BioEssays(
- Contribution to journal › Scientific review
-
Mark
The AAV-α-Synuclein Model of Parkinson's Disease : An Update
2024) In Journal of Parkinson's Disease(
- Contribution to journal › Scientific review
-
Mark
The basal forebrain cholinergic system as target for cell replacement therapy in Parkinson's disease
(
- Contribution to journal › Scientific review
- 2023
-
Mark
Restorative cell and gene therapies for Parkinson's disease
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Athymic Nude Rat Brain Atlas
2023)(
- Book/Report › Book
-
Mark
Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson's disease, STEM-PD
(
- Contribution to journal › Article
- 2022
-
Mark
A Combined α-Synuclein/Fibril (SynFib) Model of Parkinson-Like Synucleinopathy Targeting the Nigrostriatal Dopamine System
(
- Contribution to journal › Scientific review
- 2021
-
Mark
In vivo conversion of dopamine neurons in mouse models of Parkinson's disease - a future approach for regenerative therapy?
(
- Contribution to journal › Scientific review
-
Mark
Stem Derived Dopamine Neurons : Will They Replace DBS as the Leading Neurosurgical Treatment for Parkinson's Disease?
(
- Contribution to journal › Article
-
Mark
GDNF Therapy : Can We Make It Work?
(
- Contribution to journal › Article
-
Mark
Dopamine Cell Therapy : From Cell Replacement to Circuitry Repair
(
- Contribution to journal › Scientific review
-
Mark
Repairing the Parkinson Brain
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Grafts Derived from an α-Synuclein Triplication Patient Mediate Functional Recovery but Develop Disease-Associated Pathology in the 6-OHDA Model of Parkinson's Disease
(
- Contribution to journal › Article
- 2020
-
Mark
Transsynaptic tracing and its emerging use to assess graftreconstructed neural circuits
(
- Contribution to journal › Article
-
Mark
Preface : The evolving scenario of Parkinson's research
(
- Chapter in Book/Report/Conference proceeding › Foreword/Postscript
-
Mark
BDNF Overexpression Increases Striatal D3 Receptor Level at Striatal Neurons and Exacerbates D1-Receptor Agonist-Induced Dyskinesia
(
- Contribution to journal › Article
-
Mark
Animal Models of Parkinson's Disease : Are They Useful or Not?
(
- Contribution to journal › Scientific review
-
Mark
Parkinson’s disease laterality : a 11C-PE2I PET imaging study
2020) In Journal of Neurology(
- Contribution to journal › Article
-
Mark
Animal models for preclinical Parkinson´s research: An update and critical appraisal
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
From Skin to Brain : A Parkinson's Disease Patient Transplanted with His Own Cells
(
- Contribution to journal › Article
-
Mark
Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model of PD
2020) In Proceedings of the National Academy of Sciences of the United States of America 117(26). p.15209-15220(
- Contribution to journal › Article
-
Mark
GDNF and Parkinson's Disease : Where Next? A Summary from a Recent Workshop
(
- Contribution to journal › Article
-
Mark
Neuronal Replacement as a Tool for Basal Ganglia Circuitry Repair : 40 Years in Perspective
(
- Contribution to journal › Scientific review
- 2019
-
Mark
The amphetamine induced rotation test : A re-assessment of its use as a tool to monitor motor impairment and functional recovery in rodent models of Parkinson's disease
(
- Contribution to journal › Scientific review
-
Mark
hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson's Disease
(
- Contribution to journal › Article
-
Mark
Vector-mediated l-3,4-dihydroxyphenylalanine delivery reverses motor impairments in a primate model of Parkinson's disease
(
- Contribution to journal › Article
-
Mark
Designing stem-cell-based dopamine cell replacement trials for Parkinson’s disease
(
- Contribution to journal › Article
- 2018
-
Mark
The serotonergic system in L-DOPA-induced dyskinesia : pre-clinical evidence and clinical perspective
(
- Contribution to journal › Article
-
Mark
Synapsin III deficiency hampers α-synuclein aggregation, striatal synaptic damage and nigral cell loss in an AAV-based mouse model of Parkinson’s disease
(
- Contribution to journal › Article
-
Mark
Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats
(
- Contribution to journal › Article
- 2017
-
Mark
Preface
(
- Chapter in Book/Report/Conference proceeding › Foreword/Postscript
-
Mark
Preface
(
- Chapter in Book/Report/Conference proceeding › Foreword/Postscript
-
Mark
Modeling Parkinson’s disease pathology by combination of fibril seeds and α-synuclein overexpression in the rat brain
2017) In Proceedings of the National Academy of Sciences of the United States of America 114(39). p.8284-8293(
- Contribution to journal › Article
-
Mark
Mechanisms and use of neural transplants for brain repair
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Replacing Dopamine Neurons in Parkinson's Disease : How did it happen?
(
- Contribution to journal › Scientific review
-
Mark
BDNF over-expression induces striatal serotonin fiber sprouting and increases the susceptibility to L-DOPA-induced dyskinesia in 6-OHDA-lesioned rats
(
- Contribution to journal › Article
- 2016
-
Mark
Emotional memory impairments induced by AAV-mediated overexpression of human α-synuclein in dopaminergic neurons of the ventral tegmental area.
(
- Contribution to journal › Article
-
Mark
α-Synuclein induced toxicity in brain stem serotonin neurons mediated by an AAV vector driven by the tryptophan hydroxylase promoter
(
- Contribution to journal › Article
-
Mark
Extensive graft-derived dopaminergic innervation is maintained 24 years after transplantation in the degenerating parkinsonian brain.
2016) In Proceedings of the National Academy of Sciences of the United States of America 113(23). p.6544-6549(
- Contribution to journal › Article
-
Mark
Are Stem Cell-Based Therapies for Parkinson's Disease Ready for the Clinic in 2016?
(
- Contribution to journal › Article
- 2015
-
Mark
Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons.
(
- Contribution to journal › Article
-
Mark
Cyclosporin promotes neurorestoration and cell replacement therapy in pre-clinical models of Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Depressive-like phenotype induced by AAV-mediated overexpression of human α-synuclein in midbrain dopaminergic neurons.
(
- Contribution to journal › Article
-
Mark
Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson's disease: a dose-finding study.
(
- Contribution to journal › Article
-
Mark
Nurr1 and Retinoid X Receptor Ligands Stimulate Ret Signaling in Dopamine Neurons and Can Alleviate α-Synuclein Disrupted Gene Expression.
(
- Contribution to journal › Article
-
Mark
Reconstruction of brain circuitry by neural transplants generated from pluripotent stem cells.
(
- Contribution to journal › Scientific review
-
Mark
The role of pallidal serotonergic function in Parkinson's disease dyskinesias: a positron emission tomography study.
(
- Contribution to journal › Article
-
Mark
Transcriptome analysis reveals transmembrane targets on transplantable midbrain dopamine progenitors.
(
- Contribution to journal › Article
-
Mark
GDNF is not required for catecholaminergic neuron survival in vivo.
(
- Contribution to journal › Letter
-
Mark
Alpha-Synuclein Produces Early Behavioral Alterations Via Striatal Cholinergic Synaptic Dysfunction by Interacting with GluN2D N-Methyl-D-Aspartate Receptor Subunit.
2015) In Biological Psychiatry(
- Contribution to journal › Article
- 2014
-
Mark
The anti-dyskinetic effect of dopamine receptor blockade is enhanced in parkinsonian rats following dopamine neuron transplantation.
(
- Contribution to journal › Article
-
Mark
Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson's Disease.
(
- Contribution to journal › Article
-
Mark
Noradrenaline neuron degeneration contributes to motor impairments and development of L-DOPA-induced dyskinesia in a rat model of Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Long-term clinical outcome of fetal cell transplantation for Parkinson disease : two case reports
(
- Contribution to journal › Article
- 2013
-
Mark
Anti-dyskinetic effect of anpirtoline in animal models of L-DOPA-induced dyskinesia
(
- Contribution to journal › Article
-
Mark
Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons
(
- Contribution to journal › Article
-
Mark
mTOR Inhibition Alleviates L-DOPA-Induced Dyskinesia in Parkinsonian Rats
(
- Contribution to journal › Article
-
Mark
Fetal dopaminergic transplantation trials and the future of neural grafting in Parkinson's disease
(
- Contribution to journal › Scientific review
-
Mark
TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity.
(
- Contribution to journal › Article
-
Mark
Generation of induced neurons via direct conversion in vivo.
(
- Contribution to journal › Article
-
Mark
TFEB: Pathogenic role and therapeutic target in Parkinson disease.
(
- Contribution to journal › Article
-
Mark
Study of the antidyskinetic effect of eltoprazine in animal models of levodopa-induced dyskinesia
(
- Contribution to journal › Article
-
Mark
NURR1 in Parkinson disease-from pathogenesis to therapeutic potential.
(
- Contribution to journal › Scientific review
-
Mark
Trophic Factor Gene Therapy for Parkinson's Disease
(
- Contribution to journal › Scientific review
-
Mark
Cell therapy for Parkinson's disease: what next?
(
- Contribution to journal › Article
- 2012
-
Mark
Impaired neurotransmission caused by overexpression of α-synuclein in nigral dopamine neurons.
(
- Contribution to journal › Article
-
Mark
Progressive neurodegenerative and behavioural changes induced by AAV-mediated overexpression of α-synuclein in midbrain dopamine neurons.
(
- Contribution to journal › Article
-
Mark
α-Synuclein-Induced Down-Regulation of Nurr1 Disrupts GDNF Signaling in Nigral Dopamine Neurons.
(
- Contribution to journal › Article
-
Mark
Serotonin Neuron Loss and Nonmotor Symptoms Continue in Parkinson's Patients Treated with Dopamine Grafts
(
- Contribution to journal › Article
-
Mark
Comparison of the behavioural and histological characteristics of the 6-OHDA and alpha-synuclein rat models of Parkinson's disease
(
- Contribution to journal › Article
-
Mark
Serotonergic and dopaminergic mechanisms in graft-induced dyskinesia in a rat model of Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Generation of Transplantable Striatal Projection Neurons from Human ESCs.
(
- Contribution to journal › Article
-
Mark
Amphetamine-induced rotation and l-DOPA-induced dyskinesia in the rat 6-OHDA model: A correlation study.
(
- Contribution to journal › Article
-
Mark
Profile of Anders Bjorklund. Interview by Beth Azar
2012) In Proceedings of the National Academy of Sciences of the United States of America 109(33). p.9-13137(
- Contribution to journal › Article
-
Mark
Introduction (Part I)
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Introduction (Part II)
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Survival, differentiation, and connectivity of ventral mesencephalic dopamine neurons following transplantation
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Alpha-Synuclein Cell-to-Cell Transfer and Seeding in Grafted Dopaminergic Neurons In Vivo.
(
- Contribution to journal › Article
- 2011
-
Mark
Graft-Induced Dyskinesias in Parkinson's Disease: High Striatal Serotonin/Dopamine Transporter Ratio
(
- Contribution to journal › Article
-
Mark
GDNF fails to exert neuroprotection in a rat {alpha}-synuclein model of Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Cell Therapeutics in Parkinson's Disease.
(
- Contribution to journal › Article
-
Mark
Direct conversion of human fibroblasts to dopaminergic neurons.
(
- Contribution to journal › Article
-
Mark
Gene therapy for Parkinson's disease shows promise.
(
- Contribution to journal › Article
- 2010
-
Mark
Recent Advances In Parkinson'S Disease: Translational And Clinical Research Preface
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Gli1 Is an Inducing Factor in Generating Floor Plate Progenitor Cells from Human Embryonic Stem Cells
(
- Contribution to journal › Article
-
Mark
Neural grafting in Parkinson's disease: unraveling the mechanisms underlying graft-induced dyskinesia
(
- Contribution to journal › Scientific review
-
Mark
Glial Cell Derived Neurotrophic Factor Does not Provide Neuroprotection Against Alpha-Synuclein-Induced Toxicity in a Rat Model of Parkinson's Disease
(
- Contribution to journal › Published meeting abstract
-
Mark
Characterization of Lewy body pathology in 12- and 16-year-old intrastriatal mesencephalic grafts surviving in a patient with Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
The Role of Norepinephrine Neurons in Motor Symptoms of Parkinson's Disease and Development of L-DOPA-Induced Dyskinesia
(
- Contribution to journal › Published meeting abstract
-
Mark
Characterization of Lewy Body Pathology in 12-and 16-Year Old Intrastriatal Mesencephalic Grafts Surviving in a Patient with Parkinson's Disease
(
- Contribution to journal › Published meeting abstract
-
Mark
Viral vector-mediated overexpression of α-synuclein as a progressive model of Parkinson's disease
(
- Contribution to journal › Scientific review
-
Mark
Serotonergic Neurons Mediate Dyskinesia Side Effects in Parkinson's Patients with Neural Transplants
(
- Contribution to journal › Article
-
Mark
The A9 dopamine neuron component in grafts of ventral mesencephalon is an important determinant for recovery of motor function in a rat model of Parkinson's disease
(
- Contribution to journal › Article
-
Mark
Characterisation of Behavioural and Neurodegenerative Changes Induced by Intranigral 6-Hydroxydopamine Lesions in a Mouse Model of Parkinson's Disease
(
- Contribution to journal › Published meeting abstract
-
Mark
New Mouse Models for Studying Postnatal Role of GDNF In Vivo
2010) 17th Annual Meeting of the American-Society-for-Neural-Therapy-and-Repair In Cell Transplantation 19(3). p.331-331(
- Contribution to journal › Published meeting abstract
-
Mark
Role of serotonin neurons in the induction of levodopa- and graft-induced dyskinesias in Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors.
(
- Contribution to journal › Article
-
Mark
Characterisation of behavioural and neurodegenerative changes induced by intranigral 6-hydroxydopamine lesions in a mouse model of Parkinson's disease.
(
- Contribution to journal › Article
-
Mark
Recent advances in Parkinson's disease : basic research. Preface
(
- Contribution to journal › Article
-
Mark
Preface
(
- Chapter in Book/Report/Conference proceeding › Foreword/Postscript