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- 2024
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Mark
Collagen VI : Role in synaptic transmission and seizure-related excitability
(
- Contribution to journal › Article
- 2023
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Mark
Optogenetics for controlling seizure circuits for translational approaches
(
- Contribution to journal › Article
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Mark
Shaping the future of European epilepsy research : Final meeting report from EPICLUSTER
(
- Contribution to journal › Article
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Mark
Cell-specific switch for epileptiform activity : critical role of interneurons in the mouse subicular network
(
- Contribution to journal › Article
- 2022
-
Mark
Transcription factor-based direct conversion of human fibroblasts to functional astrocytes
(
- Contribution to journal › Article
-
Mark
Lipid mediator n-3 docosapentaenoic acid-derived protectin D1 enhances synaptic inhibition of hippocampal principal neurons by interaction with a G-protein-coupled receptor
(
- Contribution to journal › Article
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Mark
Myo‐Inositol Limits Kainic Acid‐Induced Epileptogenesis in Rats
(
- Contribution to journal › Article
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Mark
Transplantation of Human Stem Cell-Derived GABAergic Neurons into the Early Postnatal Mouse Hippocampus to Mitigate Neurodevelopmental Disorders
2022) In Journal of visualized experiments : JoVE(
- Contribution to journal › Article
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Mark
GDNF Increases Inhibitory Synaptic Drive on Principal Neurons in the Hippocampus via Activation of the Ret Pathway
(
- Contribution to journal › Article
- 2021
-
Mark
Human stem cell‐derived gabaergic interneurons establish efferent synapses onto host neurons in rat epileptic hippocampus and inhibit spontaneous recurrent seizures
(
- Contribution to journal › Article
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Mark
Human stem cell-derived GABAergic neurons functionally integrate into human neuronal networks
(
- Contribution to journal › Article
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Mark
Meeting report : EpiXchange II brings together European epilepsy research projects to discuss latest advances
(
- Contribution to journal › Letter
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Mark
Editorial : Gene Therapy in the CNS – Progress and Prospects for Novel Therapies
(
- Contribution to journal › Debate/Note/Editorial
- 2020
-
Mark
Gene Therapy Vector Encoding Neuropeptide Y and Its Receptor Y2 for Future Treatment of Epilepsy : Preclinical Data in Rats
(
- Contribution to journal › Article
- 2019
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Mark
Long-Term, Targeted Delivery of GDNF from Encapsulated Cells Is Neuroprotective and Reduces Seizures in the Pilocarpine Model of Epilepsy
2019) In The Journal of Neuroscience : the official journal of the Society for Neuroscience 39(11). p.2144-2156(
- Contribution to journal › Article
-
Mark
Long-term effects of myoinositol on behavioural seizures and biochemical changes evoked by kainic acid induced epileptogenesis
(
- Contribution to journal › Article
-
Mark
Unilateral ex vivo gene therapy by GDNF in epileptic rats
(
- Contribution to journal › Article
-
Mark
Inhibition of epileptiform activity by neuropeptide Y in brain tissue from drug-resistant temporal lobe epilepsy patients
(
- Contribution to journal › Article
-
Mark
Advancing research toward faster diagnosis, better treatment, and end of stigma in epilepsy
2019) In Epilepsia(
- Contribution to journal › Article
-
Mark
Leaky Optoelectrical Fiber for Optogenetic Stimulation and Electrochemical Detection of Dopamine Exocytosis from Human Dopaminergic Neurons
(
- Contribution to journal › Article
-
Mark
Disease Modification by Combinatorial Single Vector Gene Therapy : A Preclinical Translational Study in Epilepsy
(
- Contribution to journal › Article
- 2018
-
Mark
Prolonged life of human acute hippocampal slices from temporal lobe epilepsy surgery
(
- Contribution to journal › Article
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Mark
Dynamic interaction of local and transhemispheric networks is necessary for progressive intensification of hippocampal seizures
(
- Contribution to journal › Article
-
Mark
Preserved function of afferent parvalbumin-positive perisomatic inhibitory synapses of dentate granule cells in rapidly kindled mice
(
- Contribution to journal › Article
- 2017
-
Mark
Altered chloride homeostasis decreases the action potential threshold and increases hyperexcitability in hippocampal neurons
(
- Contribution to journal › Article
-
Mark
Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus
(
- Contribution to journal › Article
-
Mark
Toward an Optogenetic Therapy for Epilepsy
2017) p.292-307(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Epilepsy and optogenetics : Can seizures be controlled by light?
(
- Contribution to journal › Scientific review
-
Mark
Common data elements and data management : Remedy to cure underpowered preclinical studies
(
- Contribution to journal › Article
- 2016
-
Mark
Translational approach for gene therapy in epilepsy: Model system and unilateral overexpression of neuropeptide Y and Y2 receptors.
(
- Contribution to journal › Article
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Mark
DREADDs suppress seizure-like activity in a mouse model of pharmacoresistant epileptic brain tissue
(
- Contribution to journal › Article
-
Mark
Advances in the development of biomarkers for epilepsy
(
- Contribution to journal › Scientific review
-
Mark
Short-term grafting of human neural stem cells : Electrophysiological properties and motor behavioral amelioration in experimental Parkinson’s disease
(
- Contribution to journal › Article
-
Mark
Optogenetic control of human neurons in organotypic brain cultures
(
- Contribution to journal › Article
- 2015
-
Mark
Differential Effect of Neuropeptides on Excitatory Synaptic Transmission in Human Epileptic Hippocampus.
(
- Contribution to journal › Article
- 2014
-
Mark
How Might Novel Technologies Such as Optogenetics Lead to Better Treatments in Epilepsy?
(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
A compact multifunctional microfluidic platform for exploring cellular dynamics in real-time using electrochemical detection
(
- Contribution to journal › Article
-
Mark
WONOEP appraisal: Optogenetic tools to suppress seizures and explore the mechanisms of epileptogenesis
(
- Contribution to journal › Article
-
Mark
Encapsulated galanin-producing cells attenuate focal epileptic seizures in the hippocampus.
(
- Contribution to journal › Article
-
Mark
Global Optogenetic Activation of Inhibitory Interneurons during Epileptiform Activity.
(
- Contribution to journal › Article
-
Mark
Optogenetics reveal delayed afferent synaptogenesis on grafted human induced pluripotent stem cell-derived neural progenitors.
(
- Contribution to journal › Article
-
Mark
Optogenetic inhibition of chemically induced hypersynchronized bursting in mice.
(
- Contribution to journal › Article
- 2013
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Mark
Proposal for a "phase II" multicenter trial model for preclinical new antiepilepsy therapy development
(
- Contribution to journal › Article
-
Mark
An optogenetic approach in epilepsy.
(
- Contribution to journal › Scientific review
-
Mark
Epilepsy therapy development: Technical and methodologic issues in studies with animal models
(
- Contribution to journal › Article
- 2012
-
Mark
Y5 neuropeptide Y receptor overexpression in mice neither affects anxiety- and depression-like behaviours nor seizures but confers moderate hyperactivity
(
- Contribution to journal › Article
-
Mark
Neuropeptide Y Y1 Receptor Hippocampal Overexpression Via Viral Vectors Is Associated With Modest Anxiolytic-Like and Proconvulsant Effects in Mice
(
- Contribution to journal › Article
-
Mark
VEGF receptor-2 (flk-1) overexpression in mice counteracts focal epileptic seizures.
(
- Contribution to journal › Article
-
Mark
Human midbrain precursors activate the expected developmental genetic program and differentiate long-term to functional A9 dopamine neurons in vitro. Enhancement by Bcl-X-L
(
- Contribution to journal › Article
-
Mark
Altered profile of basket cell afferent synapses in hyper-excitable dentate gyrus revealed by optogenetic and two-pathway stimulations.
(
- Contribution to journal › Article
-
Mark
Combined gene overexpression of neuropeptide Y and its receptor Y5 in the hippocampus suppresses seizures
(
- Contribution to journal › Article
-
Mark
Novel approaches to epilepsy treatment.
2012) In Epilepsia(
- Contribution to journal › Article
- 2011
-
Mark
The treatment of neurological diseases under a new light: the importance of optogenetics.
(
- Contribution to journal › Scientific review
-
Mark
Activity-dependent long-term plasticity of afferent synapses on grafted stem/progenitor cell-derived neurons.
(
- Contribution to journal › Article
-
Mark
Functional integration of new hippocampal neurons following insults to the adult brain is determined by characteristics of pathological environment.
(
- Contribution to journal › Article
-
Mark
Seizure-induced neurogenesis in the adult brain.
(
- Contribution to journal › Article
-
Mark
Functional integration of grafted neural stem cell-derived dopaminergic neurons monitored by optogenetics in an in vitro Parkinson model.
(
- Contribution to journal › Article
-
Mark
Light-activated channels in acute seizures.
(
- Contribution to journal › Article
-
Mark
Tuning afferent synapses of hippocampal interneurons by neuropeptide Y.
(
- Contribution to journal › Article
- 2010
-
Mark
Gene therapy of focal-onset epilepsy by adeno-associated virus vector-mediated overexpression of neuropeptide Y
(
- Contribution to journal › Article
-
Mark
Functional properties of the human ventral mesencephalic neural stem cell line hVM1.
(
- Contribution to journal › Article
-
Mark
Adeno-associated viral vector-induced overexpression of neuropeptide Y Y2 receptors in the hippocampus suppresses seizures.
(
- Contribution to journal › Article
- 2009
-
Mark
BDNF downregulates 5-HT2A receptor protein levels in hippocampal cultures
(
- Contribution to journal › Article
-
Mark
Combination Gene Therapy For Epilepsy: Npy-Y2 Receptor Transfection Strategy In Animal Models
(
- Contribution to journal › Published meeting abstract
-
Mark
VASCULAR ENDOTHELIAL GROWTH FACTOR SUPPRESSES EPILEPTIC ACTIVITY IN MICE
(
- Contribution to journal › Published meeting abstract
-
Mark
Suppressed Epileptiform Activity By Opto-Genetic Cell Control In Vitro
(
- Contribution to journal › Published meeting abstract
-
Mark
Neurogenesis In The Dentate Gyrus: Adaptive Alterations Of Synaptic Drive On Cells Born In Epileptic And Inflammatory Environment
(
- Contribution to journal › Published meeting abstract
-
Mark
NEUROPEPTIDE Y DECREASES SYNAPTIC TRANSMISSION ONTO CCK-POSITIVE BASKET CELLS IN THE DENTATE GYRUS OF THE HIPPOCAMPUS
(
- Contribution to journal › Published meeting abstract
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Mark
Epilepsy and Gene Therapy: Resculpturing Synaptic Transmission with Neuropeptides
2009) p.1430-1434(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Optogenetic control of epileptiform activity.
(
- Contribution to journal › Article
-
Mark
GDNF released from encapsulated cells suppresses seizure activity in the epileptic hippocampus.
(
- Contribution to journal › Article
-
Mark
Hippocampal NPY gene transfer attenuates seizures without affecting epilepsy-induced impairment of LTP.
(
- Contribution to journal › Article
-
Mark
Novel perspectives in treatment of epilepsy.
(
- Contribution to journal › Article
-
Mark
Neural stem and progenitor cells retain their potential for proliferation and differentiation into functional neurons despite lower number in aged brain.
2009) In The Journal of Neuroscience : the official journal of the Society for Neuroscience 29(14). p.4408-4419(
- Contribution to journal › Article
- 2008
-
Mark
NPY gene transfer in the hippocampus attenuates synaptic plasticity and learning.
(
- Contribution to journal › Article
-
Mark
Activity-dependent volume transmission by transgene NPY attenuates glutamate release and LTP in subiculum
(
- Contribution to journal › Article
-
Mark
Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice
(
- Contribution to journal › Article
-
Mark
Inflammation regulates functional integration of neurons born in adult brain.
2008) In The Journal of Neuroscience : the official journal of the Society for Neuroscience 28(47). p.12477-12488(
- Contribution to journal › Article
- 2007
-
Mark
Brain area, age and viral vector-specific glial cell-line-derived neurotrophic factor expression and transport in rat.
(
- Contribution to journal › Article
-
Mark
Seizure Suppression by GDNF Gene Therapy in Animal Models of Epilepsy.
(
- Contribution to journal › Article
-
Mark
Galanin gene transfer curtails generalized seizures in kindled rats without altering hippocampal synaptic plasticity
(
- Contribution to journal › Article
- 2006
-
Mark
Environment Matters: Synaptic Properties of Neurons Born in the Epileptic Adult Brain Develop to Reduce Excitability.
(
- Contribution to journal › Article
-
Mark
Galanin expressed in the excitatory fibers attenuates synaptic strength and generalized seizures in the piriform cortex of mice.
(
- Contribution to journal › Article
-
Mark
Angels and demons: neurotrophic factors and epilepsy
(
- Contribution to journal › Scientific review
-
Mark
Decreased expression of brain-derived neurotrophic factor in BDNF(+/-) mice is associated with enhanced recovery of motor performance and increased neuroblast number following experimental stroke.
(
- Contribution to journal › Article
- 2005
-
Mark
Functional properties and synaptic integration of genetically labelled dopaminergic neurons in intrastriatal grafts.
(
- Contribution to journal › Article
-
Mark
Differential suppression of seizures via Y2 and Y5 neuropeptide Y receptors.
(
- Contribution to journal › Article
-
Mark
Forebrain acetylcholine regulates adult hippocampal neurogenesis and learning.
(
- Contribution to journal › Article
-
Mark
Galanin and kindling
(
- Chapter in Book/Report/Conference proceeding › Paper in conference proceeding
-
Mark
Chronic BDNF deficiency permanently modifies excitatory synapses in the piriform cortex.
(
- Contribution to journal › Article
- 2004
-
Mark
Neuropeptide Y Y5 receptors suppress in vitro spontaneous epileptiform bursting in the rat hippocampus.
(
- Contribution to journal › Article
-
Mark
Neuropeptide Y and seizures: effects of exogenously applied ligands
(
- Contribution to journal › Scientific review
- 2003
-
Mark
Kindling alters entorhinal cortex-hippocampal interaction by increased efficacy of presynaptic GABA(B) autoreceptors in layer III of the entorhinal cortex
(
- Contribution to journal › Article
- 2002
-
Mark
Neuropeptide Y inhibits in vitro epileptiform activity in the entorhinal cortex of mice.
(
- Contribution to journal › Article
-
Mark
Grafted neural stem cells develop into functional pyramidal neurons and integrate into host cortical circuitry.
(
- Contribution to journal › Article
- 2001
-
Mark
Septal cholinergic neurons suppress seizure development in hippocampal kindling in rats: comparison with noradrenergic neurons
(
- Contribution to journal › Article
-
Mark
Generation of regionally specified neurons in expanded glial cultures derived from the mouse and human lateral ganglionic eminence
(
- Contribution to journal › Article
-
Mark
Suppressed kindling epileptogenesis in mice with ectopic overexpression of galanin
(
- Contribution to journal › Article
-
Mark
Changes in GABA(B) receptor immunoreactivity after recurrent seizures in rats
(
- Contribution to journal › Article
- 2000
-
Mark
Development and persistence of kindling epilepsy are impaired in mice lacking glial cell line-derived neurotrophic factor family receptor α2
2000) In Proceedings of the National Academy of Sciences of the United States of America 97(22). p.12312-12317(
- Contribution to journal › Article
- 1998
-
Mark
Suppression of kindling epileptogenesis in rats by intrahippocampal cholinergic grafts
(
- Contribution to journal › Article
-
Mark
Epileptogenesis induced by rapidly recurring seizures in genetically fast- but not slow-kindling rats
(
- Contribution to journal › Article
-
Mark
Dynamic changes of brain-derived neurotrophic factor protein levels in the rat forebrain after single and recurring kindling-induced seizures
(
- Contribution to journal › Article
- 1997
-
Mark
Effects of cholinergic denervation on seizure development and neurotrophin messenger RNA regulation in rapid hippocampal kindling
(
- Contribution to journal › Article
-
Mark
Apoptosis and proliferation of dentate gyrus neurons after single and intermittent limbic seizures
(
- Contribution to journal › Article
-
Mark
Suppressed kindling epileptogenesis and perturbed BDNF and TrkB gene regulation in NT-3 mutant mice
(
- Contribution to journal › Article
-
Mark
Mossy fibre sprouting: evidence against a facilitatory role in epileptogenesis
(
- Contribution to journal › Article
-
Mark
Differentsirovka neironov golubovatogo mesta posle ikh allotransplantatsii v predvaritel'no denervirovannyi gippokamp belykh krys.
(
- Contribution to journal › Article
- 1996
-
Mark
Seizure-induced differential expression of messenger RNAs for neurotrophins and their receptors in genetically fast and slow kindling rats
(
- Contribution to journal › Article
-
Mark
Regulation of neuronal nitric oxide synthase mRNA levels in rat brain by seizure activity
(
- Contribution to journal › Article
-
Mark
Immunolesioning of basal forebrain cholinergic neurons facilitates hippocampal kindling and perturbs neurotrophin messenger RNA regulation
(
- Contribution to journal › Article
-
Mark
Expression of neurotrophin mRNAs in the postischemic phase
(
- Contribution to journal › Article
-
Mark
Delayed kindling development after rapidly recurring seizures: relation to mossy fiber sprouting and neurotrophin, GAP-43 and dynorphin gene expression
(
- Contribution to journal › Article
-
Mark
Neurotrophins in kindling epilepsy: neuronal protection or induction of sprouting and epileptogenesis?
1996) p.417-417(
- Chapter in Book/Report/Conference proceeding › Book chapter
- 1995
-
Mark
Co-expression of TrkB and TrkC receptors in CNS neurones suggests regulation by multiple neurotrophins
(
- Contribution to journal › Article
-
Mark
Regulation of brain-derived neurotrophic factor gene expression after transient middle cerebral artery occlusion with and without brain damage
(
- Contribution to journal › Article
-
Mark
Suppressed epileptogenesis in BDNF mutant mice
(
- Contribution to journal › Article
- 1994
-
Mark
Seizure development and noradrenaline release in kindling epilepsy after noradrenergic reinnervation of the subcortically deafferented hippocampus by superior cervical ganglion or fetal locus coeruleus grafts
(
- Contribution to journal › Article
-
Mark
Seizure suppression in kindling epilepsy by intracerebral implants of GABA- but not by noradrenaline-releasing polymer matrices
(
- Contribution to journal › Article
-
Mark
Biphasic differential changes of GABAA receptor subunit mRNA levels in dentate gyrus granule cells following recurrent kindling-induced seizures
(
- Contribution to journal › Article
-
Mark
Neurotrophins and brain insults
(
- Contribution to journal › Scientific review
-
Mark
Brain insults in rats induce increased expression of the BDNF gene through differential use of multiple promoters
(
- Contribution to journal › Article
-
Mark
BDNF makes cultured dentate granule cells more resistant to hypoglycemic damage
(
- Contribution to journal › Article
-
Mark
Grafts in models of epilepsy
1994) p.387-387(
- Chapter in Book/Report/Conference proceeding › Book chapter
-
Mark
Seizure development and noradrenaline release in kindling epilepsy after noradrenergic reinnervation of the subcortically deafferented hippocmapus by superior cervical ganglion or fetal locus coeruleus grafts
(
- Contribution to journal › Article
-
Mark
BDNF makes cultured dentate granule cells more resistant to hypoglycaemic damage
(
- Contribution to journal › Article
- 1993
-
Mark
Differential regulation of N-methyl-D-aspartate receptor subunit messenger RNAs in kindling-induced epileptogenesis
(
- Contribution to journal › Article
-
Mark
Rapid increase of BDNF mRNA levels in cortical neurons following spreading depression : regulation by glutamatergic mechanisms independent of seizure activity
(
- Contribution to journal › Article
-
Mark
Coexpression of neurotrophins and their receptors in neurons of the central nervous system
1993) In Proceedings of the National Academy of Sciences of the United States of America 90(14). p.5-6711(
- Contribution to journal › Article
-
Mark
Increased production of the TrkB protein tyrosine kinase receptor after brain insults
(
- Contribution to journal › Article
-
Mark
Regulation of neurotrophin and trkA, trkB and trkC tyrosine kinase receptor messenger RNA expression in kindling
(
- Contribution to journal › Article
- 1992
-
Mark
Widespread increase of nerve growth factor protein in the rat forebrain after kindling-induced seizures
(
- Contribution to journal › Article
-
Mark
Regional Forebrain Noradrenalin Release in Response to Focal and Generalized Seizures Induced by Hippocampal Kindling Stimulation
(
- Contribution to journal › Article
- 1989
-
Mark
Vliianie iskusstvennoǐ poliarizatsii membrany na TSPS neǐronov sensomotornoǐ kory koshki.
(
- Contribution to journal › Article
- 1988
-
Mark
Participation of Ca2+-dependent K+-conductance in membrane hyperpolarization of pyramidal neurons in the cat sensorimotor cortex
(
- Contribution to journal › Article
- 1986
-
Mark
Vliianie vnutrikletochnoǐ in"ektsii ionov khlora na tormoziashchiǐ postsinapticheskiǐ potentsial i postzalpovuiu giperpoliarizatsiiu neǐronov sensomotornoǐ kory koshki.
(
- Contribution to journal › Article