Division of Molecular Medicine and Gene Therapy
251 – 500 of 575
- show: 250
- |
- sort: year (new to old)
Close
Embed this list
<iframe src=" "
width=" "
height=" "
allowtransparency="true"
frameborder="0">
</iframe>
- 2016
-
Mark
The stem cell niche finds its true north
(
- Contribution to journal › Scientific review
-
Mark
Endoplasmic reticulum stress regulation in hematopoietic stem cells
(
- Contribution to journal › Article
-
Mark
IL1RAP antibodies block IL-1-induced expansion of candidate CML stem cells and mediate cell killing in xenograft models
(
- Contribution to journal › Article
-
Mark
The european hematology association roadmap for european hematology research : A consensus document
(
- Contribution to journal › Article
-
Mark
Direct Conversion of Fibroblasts to Megakaryocyte Progenitors
(
- Contribution to journal › Article
-
Mark
Defining the Minimal Factors Required for Erythropoiesis through Direct Lineage Conversion
(
- Contribution to journal › Article
-
Mark
Cardiovascular events associated with use of tyrosine kinase inhibitors in chronic myeloid leukemia
(
- Contribution to journal › Article
-
Mark
BCAT1, a key prognostic predictor of hepatocellular carcinoma, promotes cell proliferation and induces chemoresistance to cisplatin
(
- Contribution to journal › Article
-
Mark
Regulation and Function of Lentiviral Vector-Mediated TCIRG1 Expression in Osteoclasts from Patients with Infantile Malignant Osteopetrosis : Implications for Gene Therapy
(
- Contribution to journal › Article
-
Mark
Leukemic stem cell quantification in newly diagnosed chronic myeloid leukemia patients predicts response to nilotinib therapy
(
- Contribution to journal › Article
-
Mark
Cyclic AMP Signaling through Epac Axis Modulates Human Hemogenic Endothelium and Enhances Hematopoietic Cell Generation
(
- Contribution to journal › Article
-
Mark
Pathways that govern hematopoietic stem cell fate
2016)(
- Thesis › Doctoral thesis (compilation)
-
Mark
Genome-wide RNAi Screen Identifies Cohesin Genes as Modifiers of Renewal and Differentiation in Human HSCs
(
- Contribution to journal › Article
-
Mark
A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional network
(
- Contribution to journal › Article
-
Mark
G protein-coupled Receptor 30 (GPR30) PDZ-dependently and Constitutively Increases ERK1/2 Signaling Through Calcineurin and Kinase Suppressor of Ras 2 (KSR2)
(
- Contribution to journal › Published meeting abstract
-
Mark
Expansion and Biased Commitment of Hematopoietic Stem Cells Towards Erythroid Cells upon Acute Anemia Induction
(
- Contribution to journal › Published meeting abstract
- 2015
-
Mark
Cell and gene therapy for blood disorders. Modeling of novel treatment strategies for Gaucher type 1 disease and Diamond-Blackfan anemia in mice.
(
- Thesis › Doctoral thesis (compilation)
-
Mark
Towards Generation of Human Hematopoietic Stem Cells from Pluripotent Stem Cells.
(
- Thesis › Doctoral thesis (compilation)
-
Mark
Protein receptor-independent plasma membrane remodeling by HAMLET: a tumoricidal protein-lipid complex.
(
- Contribution to journal › Article
-
Mark
Monitoring Low Molecular Weight Heparins at Therapeutic Levels: Dose-Responses of, and Correlations and Differences between aPTT, Anti-Factor Xa and Thrombin Generation Assays.
(
- Contribution to journal › Article
-
Mark
Integrin Based Isolation Enables Purification of Murine Lineage Committed Cardiomyocytes
(
- Contribution to journal › Article
-
Mark
Retinoic Acid regulates hematopoietic development from human pluripotent stem cells.
(
- Contribution to journal › Article
-
Mark
TGIF1 is a negative regulator of MLL-rearranged acute myeloid leukemia.
(
- Contribution to journal › Article
-
Mark
Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia.
(
- Contribution to journal › Article
-
Mark
The Tyrosine Kinase Inhibitors Imatinib and Dasatinib Reduce Myeloid Suppressor Cells and Release Effector Lymphocyte Responses
(
- Contribution to journal › Article
-
Mark
Coexpression of hyperactivated AKT1 with additional genes activated in leukemia drives hematopoietic progenitor cells to cell cycle block and apoptosis.
(
- Contribution to journal › Article
-
Mark
Inhibition of UDP-glucosylceramide synthase in mice prevents Gaucher disease-associated B-cell malignancy
(
- Contribution to journal › Article
-
Mark
The activation loop tyrosine 823 is essential for the transforming capacity of the c-Kit oncogenic mutant D816V.
(
- Contribution to journal › Article
-
Mark
Loss of HIF-1α accelerates murine FLT-3ITD-induced myeloproliferative neoplasia.
(
- Contribution to journal › Article
-
Mark
Two new routes to make blood: Hematopoietic specification from pluripotent cell lines vs. reprogramming of somatic cells.
(
- Contribution to journal › Article
-
Mark
Second malignancies following treatment of chronic myeloid leukaemia in the tyrosine kinase inhibitor era
(
- Contribution to journal › Article
-
Mark
Dasatinib induces fast and deep responses in newly diagnosed chronic myeloid leukaemia patients in chronic phase: clinical results from a randomised phase-2 study (NordCML006)
(
- Contribution to journal › Article
-
Mark
Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond-Blackfan anaemia.
(
- Contribution to journal › Article
-
Mark
TGF-β signaling in the control of hematopoietic stem cells.
(
- Contribution to journal › Article
-
Mark
Jarid2 regulates hematopoietic stem cell function by acting with polycomb repressive complex 2.
(
- Contribution to journal › Article
-
Mark
Disruption of the 5S RNP-Mdm2 interaction significantly improves the erythroid defect in a mouse model for Diamond-Blackfan anemia.
(
- Contribution to journal › Article
-
Mark
Lentiviral gene therapy using cellular promoters cures type 1 Gaucher disease in mice.
(
- Contribution to journal › Article
-
Mark
ERG promotes the maintenance of hematopoietic stem cells by restricting their differentiation.
(
- Contribution to journal › Article
-
Mark
Case-report: EBV driven lymphoproliferative disorder associated with Ruxolitinib.
(
- Contribution to journal › Article
-
Mark
Young woman with mild bone marrow dysplasia, GATA2 and ASXL1 mutation treated with allogeneic hematopoietic stem cell transplantation.
(
- Contribution to journal › Article
- 2014
-
Mark
Development of Novel Models for Studying Osteoclasts
(
- Thesis › Doctoral thesis (compilation)
-
Mark
Modeling chronic myeloid leukemia in immunodeficient mice reveals expansion of aberrant mast cells and accumulation of pre-B cells.
(
- Contribution to journal › Article
-
Mark
Sortilin expression is essential for pro-nerve growth factor-induced apoptosis of rat vascular smooth muscle cells.
(
- Contribution to journal › Article
-
Mark
A Comparison of Osteoclast-Rich and Osteoclast-Poor Osteopetrosis in Adult Mice Sheds Light on the Role of the Osteoclast in Coupling Bone Resorption and Bone Formation
(
- Contribution to journal › Article
-
Mark
Hematopoietic Stem Cells Are Intrinsically Protected against MLL-ENL-Mediated Transformation.
(
- Contribution to journal › Article
-
Mark
Dppa5 improves hematopoietic stem cell activity by reducing endoplasmic reticulum stress.
(
- Contribution to journal › Article
-
Mark
The SKI proto-oncogene enhances the in vivo repopulation of hematopoietic stem cells and causes myeloproliferative disease
(
- Contribution to journal › Article
-
Mark
Regulation of Hematopoietic Stem Cells
(
- Thesis › Doctoral thesis (compilation)
-
Mark
Optogenetic control of insulin secretion in intact pancreatic islets with β-cell-specific expression of Channelrhodopsin-2.
(
- Contribution to journal › Article
-
Mark
RNA interference screening to detect targetable molecules in hematopoietic stem cells.
(
- Contribution to journal › Scientific review
-
Mark
A Central Role for GRB10 in Regulation of Islet Function in Man.
(
- Contribution to journal › Article
-
Mark
Gene therapy cures the anemia and lethal bone marrow failure in mouse model for RPS19-deficient Diamond-Blackfan anemia.
(
- Contribution to journal › Article
-
Mark
RNA-seq identifies clinically relevant fusion genes in leukemia including a novel MEF2D/CSF1R fusion responsive to imatinib.
(
- Contribution to journal › Letter
-
Mark
The nuclear localization of γ-tubulin is regulated by SadB-mediated phosphorylation.
(
- Contribution to journal › Article
-
Mark
Somatic cells with a heavy mitochondrial DNA mutational load render iPS cells with distinct differentiation defects.
(
- Contribution to journal › Article
-
Mark
HIF-1α can act as a tumor suppressor gene in murine Acute Myeloid Leukemia.
(
- Contribution to journal › Article
-
Mark
Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism.
(
- Contribution to journal › Article
-
Mark
The epigenetic landscape of aneuploidy: constitutional mosaicism leading the way?
(
- Contribution to journal › Article
-
Mark
Hypoxic induction of vascular endothelial growth factor regulates erythropoiesis but not hematopoietic stem cell function in the fetal liver.
(
- Contribution to journal › Article
-
Mark
Musculoskeletal Pain in Patients With Chronic Myeloid Leukemia After Discontinuation of Imatinib: A Tyrosine Kinase Inhibitor Withdrawal Syndrome?
(
- Contribution to journal › Letter
-
Mark
Myelodysplastic Syndromes Are Propagated by Rare and Distinct Human Cancer Stem Cells In Vivo.
(
- Contribution to journal › Article
-
Mark
Brain pericytes acquire a microglial phenotype after stroke.
(
- Contribution to journal › Article
-
Mark
Gene expression profiling to define the cell intrinsic role of the SKI proto-oncogene in hematopoiesis and myeloid neoplasms.
(
- Contribution to journal › Article
- 2013
-
Mark
Expression of Integrin A2 Receptor in Human Cord Blood Cd34+Cd38-Cd90+ Stem Cells Engrafting Long-Term in Nod/Scid-Il2rγ(C) Null Mice.
(
- Contribution to journal › Article
-
Mark
Osteoclasts are not crucial for hematopoietic stem cell maintenance in adult mice
(
- Contribution to journal › Article
-
Mark
The Tetraspanin CD9 Affords High-Purity Capture of All Murine Hematopoietic Stem Cells
(
- Contribution to journal › Article
-
Mark
Adenovirus Serotype 5 Vectors with Tat-PTD Modified Hexon and Serotype 35 Fiber Show Greatly Enhanced Transduction Capacity of Primary Cell Cultures
(
- Contribution to journal › Article
-
Mark
Defining Regulators of Human Hematopoietic Stem Cells
(
- Thesis › Doctoral thesis (compilation)
-
Mark
Functional and genetic characterization of the non-lysosomal glucosylceramidase 2 as a modifier for Gaucher disease
(
- Contribution to journal › Article
-
Mark
Impact of malignant stem cell burden on therapy outcome in newly diagnosed chronic myeloid leukemia patients
(
- Contribution to journal › Article
-
Mark
Tyrosine kinase inhibitor usage, treatment outcome, and prognostic scores in CML: report from the population-based Swedish CML registry
(
- Contribution to journal › Article
-
Mark
40K glycoPEGylated, recombinant FVIIa: 3-month, double-blind, randomized trial of safety, pharmacokinetics, and preliminary efficacy in hemophilia patients with inhibitors.
(
- Contribution to journal › Article
-
Mark
Increased glucocerebrosidase (GBA) 2 activity in GBA1 deficient mice brains and in Gaucher leucocytes
(
- Contribution to journal › Article
-
Mark
Lymphomyeloid Contribution of an Immune-Restricted Progenitor Emerging Prior to Definitive Hematopoietic Stem Cells.
(
- Contribution to journal › Article
-
Mark
Response to letter to the editor 'Serum cystatin-C levels correlate with endothelial dysfunction in patients with the metabolic syndrome'
(
- Contribution to journal › Letter
-
Mark
B cell lymphoma and myeloma in murine Gaucher's disease
(
- Contribution to journal › Article
-
Mark
Lentiviral gene transfer of TCIRG1 into peripheral blood CD34(+) cells restores osteoclast function in infantile malignant osteopetrosis.
(
- Contribution to journal › Article
-
Mark
Interfering with histone demethylases in HSCs.
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Selective killing of candidate AML stem cells by antibody targeting of IL1RAP.
(
- Contribution to journal › Article
-
Mark
Identification of the chemokine CCL28 as a growth and survival factor for human hematopoietic stem- and progenitor cells.
(
- Contribution to journal › Article
-
Mark
Fetal hepatic progenitors support long-term expansion of hematopoietic stem cells
(
- Contribution to journal › Article
-
Mark
FACS binding assay for analysing GDNF interactions.
(
- Contribution to journal › Article
-
Mark
Sox4 Is a Key Oncogenic Target in C/EBP alpha Mutant Acute Myeloid Leukemia
(
- Contribution to journal › Article
-
Mark
A Robust Screening Assay For Diamond Blackfan Anemia Candidate Drugs
(
- Contribution to journal › Published meeting abstract
- 2012
-
Mark
Deciphering the Pathogenesis of Acute Myeloid Leukemia
(
- Thesis › Doctoral thesis (compilation)
-
Mark
Murine ameloblasts are immunonegative for Tcirg1, the v-H-ATPase subunit essential for the osteoclast plasma proton pump
(
- Contribution to journal › Article
-
Mark
Genetic modeling of the Hippo pathway in hematopoietic stem cells
(
- Thesis › Doctoral thesis (compilation)
-
Mark
SPARC is dispensable for murine hematopoiesis, despite its suspected pathophysiological role in 5q- myelodysplastic syndrome.
(
- Contribution to journal › Article
-
Mark
Targeting the hematopoietic stem cell to correct osteopetrosis
(
- Thesis › Doctoral thesis (compilation)
-
Mark
Molecular and cellular effects of oncogene cooperation in a genetically accurate AML mouse model.
(
- Contribution to journal › Article
-
Mark
Modeling Diamond-Blackfan Anemia in the Mouse: Disease Pathogenesis and Evaluation of Novel Therapies
(
- Thesis › Doctoral thesis (compilation)
-
Mark
Normal Hematopoietic Stem Cell Function in Mice with Enforced Expression of the Hippo Signaling Effector YAP1.
(
- Contribution to journal › Article
-
Mark
Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions
(
- Contribution to journal › Article
-
Mark
Killer-cell immunoglobulin-like receptor gene profile predicts good molecular response to dasatinib therapy in chronic myeloid leukemia
(
- Contribution to journal › Article
-
Mark
Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia.
(
- Contribution to journal › Article
-
Mark
Human hematopoietic stem/progenitor cells overexpressing Smad4 exhibit impaired reconstitution potential in vivo.
(
- Contribution to journal › Article
-
Mark
Do HSCs divide asymmetrically?
(
- Contribution to journal › Article
-
Mark
Hematopoietic stem cells are regulated by Cripto, as an intermediary of HIF-1α in the hypoxic bone marrow niche.
(
- Contribution to journal › Article
-
Mark
RNAi screen identifies MAPK14 as a druggable suppressor of human hematopoietic stem cell expansion.
(
- Contribution to journal › Article
-
Mark
Common signaling networks characterize leukemia-initiating cells in acute myeloid leukemia.
(
- Contribution to journal › Article
-
Mark
Angptl4 maintains in vivo repopulation capacity of CD34(+) human cord blood cells.
(
- Contribution to journal › Article
-
Mark
Progress towards Mechanism-Based Treatment for Diamond-Blackfan Anemia.
(
- Contribution to journal › Article
- 2011
-
Mark
Targeting Expression of the Leukemogenic PML-RAR alpha Fusion Protein by Lentiviral Vector-Mediated Small Interfering RNA Results in Leukemic Cell Differentiation and Apoptosis
(
- Contribution to journal › Article
-
Mark
Regulation of morphogen signalling during neural patterning in the Xenopus embryo
(
- Thesis › Doctoral thesis (compilation)
-
Mark
Efficient Generation of Hematopoietic Precursors and Progenitors From Human Pluripotent Stem Cell Lines.
(
- Contribution to journal › Article
-
Mark
Stem cell self-renewal: lessons from bone marrow, gut and iPS toward clinical applications
(
- Contribution to journal › Scientific review
-
Mark
The role of Smad signaling in hematopoiesis and translational hematology.
(
- Contribution to journal › Article
-
Mark
THE HYPOXIC HEMATOPOIETIC STEM CELL NICHE Consequences of Hypoxia-induced Transcription on Stem Cell Fate
(
- Thesis › Doctoral thesis (compilation)
-
Mark
Dissociation of Bone Resorption and Bone Formation in Adult Mice with a Non-Functional V-ATPase in Osteoclasts Leads to Increased Bone Strength
(
- Contribution to journal › Article
-
Mark
Stress hematopoiesis requires Erg
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche
(
- Contribution to journal › Article
-
Mark
Hypoxic induction of vascular endothelial growth factor regulates murine hematopoietic stem cell function in the low-oxygenic niche.
(
- Contribution to journal › Article
-
Mark
From stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications
(
- Contribution to journal › Scientific review
-
Mark
Proteasome Inhibition Improves the Muscle of Laminin {alpha}2 Chain Deficient Mice.
(
- Contribution to journal › Article
-
Mark
Success Story of Targeted Therapy in Chronic Myeloid Leukemia: A Population-Based Study of Patients Diagnosed in Sweden From 1973 to 2008.
(
- Contribution to journal › Article
-
Mark
(H)if blood stem cells gO 2 sleep: What can wake them up?
(
- Contribution to journal › Article
-
Mark
Joining the stem cell maintenance squad.
(
- Contribution to journal › Article
-
Mark
SMAD4 binds HOXA9 in the cytoplasm and protects primitive hematopoietic cells against nuclear activation by HOXA9 and leukemia transformation.
(
- Contribution to journal › Article
-
Mark
Successful management of a planned pregnancy in severe congenital thrombotic thrombocytopaenic purpura: the Upshaw-Schulman syndrome.
(
- Contribution to journal › Article
-
Mark
High levels of the adhesion molecule CD44 on leukemic cells generate acute myeloid leukemia relapse after withdrawal of the initial transforming event.
(
- Contribution to journal › Article
-
Mark
The Vascular Repair Process after Injury of the Carotid Artery is regulated by IL-1RI and MyD88 Signalling.
(
- Contribution to journal › Article
-
Mark
Cripto Regulates Hematopoietic Stem Cells as a Hypoxic-Niche-Related Factor through Cell Surface Receptor GRP78.
(
- Contribution to journal › Article
-
Mark
Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia.
(
- Contribution to journal › Article
-
Mark
P4-09-02: G Protein-Coupled Estrogen Receptor 1 Positively Correlates with Estrogen Receptor a Expression and Increased Distant Disease-Free Survival of Breast Cancer Patients.
(
- Contribution to journal › Published meeting abstract
- 2010
-
Mark
Development of Novel Therapies in Murine Models for Gaucher Disease
2010) 7th Annual Conference of the British-Society-for-Gene-Therapy In Human Gene Therapy 21(4). p.490-491(
- Contribution to journal › Published meeting abstract
-
Mark
A Human Model of IMO by Lentiviral Mediated shRNA Knock-down of Tcirg1 in CD34+Cells
2010) 18th Annual Congress of the European-Society-of-Gene-and-Cell-Therapy In Human Gene Therapy 21(10). p.1458-1459(
- Contribution to journal › Published meeting abstract
-
Mark
In Vitro RNA Interference Screen for Regulators of Adhesion in Hematopoietic Stem/Progenitor Cells
2010) 39th Annual Scientific Meeting of the ISEH - Society-for-Hematology-and-Stem-Cells In Experimental Hematology 38(9). p.256-256(
- Contribution to journal › Published meeting abstract
-
Mark
Chronic RPS19 Deficiency Leads to Bone Marrow Failure In a Mouse Model for Diamond Blackfan Anemia
(
- Contribution to journal › Published meeting abstract
-
Mark
CCL28 Is a Growth Factor for Human Hematopoietic Stem- and Progenitor Cells
2010) 39th Annual Scientific Meeting of the ISEH - Society-for-Hematology-and-Stem-Cells In Experimental Hematology 38(9). p.254-254(
- Contribution to journal › Published meeting abstract
-
Mark
Endothelial protein C receptor-expressing hematopoietic stem cells reside in the perisinusoidal niche in fetal liver
(
- Contribution to journal › Article
-
Mark
Altered expression and distribution of cathepsins in neuronopathic forms of Gaucher disease and in other sphingolipidoses
(
- Contribution to journal › Article
-
Mark
Role of Biallelic C/EBPalpha Mutations and FLT-3 LTD in Initiation and Maintenance of AML
2010) 39th Annual Scientific Meeting of the ISEH - Society-for-Hematology-and-Stem-Cells In Experimental Hematology 38(9). p.250-250(
- Contribution to journal › Published meeting abstract
-
Mark
Nonablative neonatal bone marrow transplantation rapidly reverses severe murine osteopetrosis despite low level engraftment and lack of selective expansion of the osteoclastic lineage.
(
- Contribution to journal › Article
-
Mark
PIM1 kinase is destabilized by ribosomal stress causing inhibition of cell cycle progression
(
- Contribution to journal › Article
-
Mark
Cripto Selectively Expands a Distinct Population of Hematopoietic Stem Cells Expressing the Cell Surface Receptor GRP78 and Strongly Induces An Immature Phenotype In Vivo After Ex Vivo Culture
(
- Contribution to journal › Published meeting abstract
-
Mark
Cripto Selectively Expands a Distinct Population Of Hematopoietic Stem Cells Expressing Cell Surface Receptor GRP78
2010) 39th Annual Scientific Meeting of the ISEH - Society-for-Hematology-and-Stem-Cells In Experimental Hematology 38(9). p.038-038(
- Contribution to journal › Published meeting abstract
-
Mark
Second-Generation BCR-ABL Kinase Inhibitors in CML
(
- Contribution to journal › Letter
-
Mark
Successful Treatment of Metachromatic Leukodystrophy Using Bone Marrow Transplantation of HoxB4 Overexpressing Cells
(
- Contribution to journal › Article
-
Mark
W41/W41 blastocyst complementation: a system for genetic modeling of hematopoiesis.
(
- Contribution to journal › Article
-
Mark
Modeling the human 8p11-myeloproliferative syndrome in immunodeficient mice
(
- Contribution to journal › Article
-
Mark
High Levels of the Adhesion Molecule CD44 on Leukemic Cells Generate Acute Myeloid Leukemia Relapse After Withdrawal of the Initial Transforming Event
(
- Contribution to journal › Published meeting abstract
-
Mark
The Success Story of Targeted Therapy In Chronic Myeloid Leukemia A Population Based Study of 3,173 Patients Diagnosed In Sweden 1973-2008
(
- Contribution to journal › Published meeting abstract
-
Mark
A recombinant adenovirus type 35 fiber knob protein sensitizes lymphoma cells to rituximab therapy
(
- Contribution to journal › Article
-
Mark
SMAD4 Sequestrates HOXA9 to Protect Hematopoietic Stem Cells Against Leukemia Transformation
(
- Contribution to journal › Published meeting abstract
-
Mark
The Proportion of Ph+CD34(+)CD38(neg) Leukemic Stem Cells In the Bone Marrow of Newly Diagnosed Patients with Chronic Myeloid Leukemia (CML) In Chronic Phase (CP) Is Variable and Correlates with High Sokal Risk, High Leukocyte Count, Low Hemoglobin Concentration, Splenomegaly and Increased Hematological Toxicity During Initial TKI Therapy Data From a Randomized Phase II NordCML006 Study
(
- Contribution to journal › Published meeting abstract
-
Mark
Forward RNAi screens in human stem cells.
(
- Contribution to journal › Article
-
Mark
Canonical BMP signaling is dispensable for hematopoietic stem cell function in both adult and fetal liver hematopoiesis, but essential to preserve colon architecture.
(
- Contribution to journal › Article
-
Mark
Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein.
(
- Contribution to journal › Article
-
Mark
Genetic analysis of dasatinib-treated chronic myeloid leukemia rapidly developing into acute myeloid leukemia with monosomy 7 in Philadelphia-negative cells.
(
- Contribution to journal › Article
- 2009
-
Mark
A Recombinant Adenovirus Type 35 Fiber Knob Protein Sensitizes Lymphoma Cells to Rituximab Therapy
2009) 12th Annual Meeting of the American Society of Gene Therapy In Molecular Therapy 17. p.240-240(
- Contribution to journal › Published meeting abstract
-
Mark
A Novel Mouse Model for RPS19-Deficient Diamond-Blackfan Anemia Locates the Erythroid Defect at CFU-E/Proerythroblast Transition
(
- Contribution to journal › Published meeting abstract
-
Mark
In an inducible model of acute myeloid leukemia, secondary hits are required to generate a leukemia relapse after removal of the initial transforming event
2009) 38th Annual Scientific Meeting of the ISEH-Society-for-Hematology-and-Stem-Cells In Experimental Hematology 37(9). p.16-16(
- Contribution to journal › Published meeting abstract
-
Mark
Forward RNAi screens in primary human hematopoietic stem/progenitor cells
(
- Contribution to journal › Article
-
Mark
Dissociation of bone resorption and bone formation in adult mice transplanted with OC/OC hematopoietic stem cells
(
- Contribution to journal › Published meeting abstract
-
Mark
Expression of P190 and P210 BCR/ABL1 in normal human CD34(+) cells induces similar gene expression profiles and results in a STAT5-dependent expansion of the erythroid lineage
(
- Contribution to journal › Article
-
Mark
No evidence for activation of the unfolded protein response in neuronopathic models of Gaucher disease
(
- Contribution to journal › Article
-
Mark
Poor vessel formation in embryos from knock-in mice expressing ALK5 with L45 loop mutation defective in Smad activation
(
- Contribution to journal › Article
-
Mark
Development of Novel Therapies in Murine Models for Gaucher Disease
(
- Chapter in Book/Report/Conference proceeding › Paper in conference proceeding
-
Mark
Assessment of CAR- or CD46-Dependent Adenoviral Vector-Mediated TRAIL Gene Therapy in Clinical Adenocarcinoma Lung Cancer Cells
(
- Contribution to journal › Article
-
Mark
Toward a stem cell gene therapy for breast cancer
(
- Contribution to journal › Article
-
Mark
Lipocalin 2 negatively controls erythroid and macrophage lineages via megalin as its receptor
2009) 38th Annual Scientific Meeting of the ISEH-Society-for-Hematology-and-Stem-Cells In Experimental Hematology 37(9). p.80-81(
- Contribution to journal › Published meeting abstract
-
Mark
Fetal Gene Therapy for Acute Neuronopathic Gaucher Disease
2009) 12th Annual Meeting of the American Society of Gene Therapy In Molecular Therapy 17. p.357-357(
- Contribution to journal › Published meeting abstract
-
Mark
THE ROLE OF BMP SIGNALING AND ENDOGLIN IN REGULATION OF HEMATOPOIESIS
(
- Thesis › Doctoral thesis (compilation)
-
Mark
Successful Low-Risk Hematopoietic Cell Therapy in a Mouse Model of Type 1 Gaucher Disease
(
- Contribution to journal › Article
-
Mark
Development of Mouse Models and Gene Therapy for Gaucher Disease
(
- Thesis › Doctoral thesis (compilation)
-
Mark
Neonatal bone marrow transplantation without prior conditioning rapidly reverses osteopetrosis in oc/oc mice despite only minimal donor cell engraftment
(
- Contribution to journal › Published meeting abstract
-
Mark
SMAD4 as a therapeutic target in hoxa9-related leukemia
2009) 38th Annual Scientific Meeting of the ISEH-Society-for-Hematology-and-Stem-Cells In Experimental Hematology 37(9). p.44-45(
- Contribution to journal › Published meeting abstract
-
Mark
Low-dose busulphan conditioning and neonatal stem cell transplantation preserves vision and restores hematopoiesis in severe murine osteopetrosis.
(
- Contribution to journal › Article
-
Mark
Prospects for gene therapy of osteopetrosis.
(
- Contribution to journal › Article
-
Mark
Is TGF-beta a stemness regulator?
(
- Contribution to journal › Article
-
Mark
Complex and context dependent regulation of hematopoiesis by TGF-beta superfamily signaling.
(
- Contribution to journal › Scientific review
-
Mark
Hematopoietic Cell-Specific Deletion of Toll-like Receptor 4 Ameliorates Hepatic and Adipose Tissue Insulin Resistance in High-Fat-Fed Mice
(
- Contribution to journal › Article
- 2008
-
Mark
Diagnosing and treating Diamond Blackfan anaemia: results of an international clinical consensus conference
(
- Contribution to journal › Scientific review
-
Mark
Hematopoietic stem cell responsiveness to exogenous signals is limited by Caspase-3
(
- Contribution to journal › Article
-
Mark
Neonatal hematopoietic stem cell transplantation following low-dose busulphan conditioning reverses osteopetrosis and preserves vision in oc/oc mice
2008) 16th Annual Congress of the European-Society-of-Gene-and-Cell-Therapy In Human Gene Therapy 19(10). p.1183-1184(
- Contribution to journal › Published meeting abstract
-
Mark
A critical role for Smad4 in the self-renewal of hematopoietic stem cells
2008) 4th Conference on Stem Cell Gene Therapy In Blood Cells, Molecules, and Diseases 40(2). p.271-271(
- Contribution to journal › Published meeting abstract
-
Mark
Brain area-specific effect of TGF-beta signaling on Wnt-dependent neural stem cell expansion
(
- Contribution to journal › Article
-
Mark
Human Primary Mensenchymal Stromal Progenitor Cells Are Highly Enriched in Both, the CD271(+)/CD146(+) and CD271(+)/CD146(-) Bone Marrow Population with the Latter Acquiring CD146 Expression upon Culture in-Vitro.
(
- Contribution to journal › Published meeting abstract
-
Mark
Enforced expression of c-Ski in adult murine hematopoiesis promotes myeloid - Differentiation, revealing an important role for c-Ski in governing hematopoietic cell fate options
2008) 37th Annual Scientific Meeting featuring the 6th International Neonatal Hematology and Immunology Meeting In Experimental Hematology 36(7, Supplement 1). p.29-29(
- Contribution to journal › Published meeting abstract
-
Mark
W41/w41 blastocyst complementation: A versatile system to study gene function in hematopotetic stem cells
2008) 37th Annual Scientific Meeting featuring the 6th International Neonatal Hematology and Immunology Meeting In Experimental Hematology 36(7, Supplement 1). p.67-68(
- Contribution to journal › Published meeting abstract
-
Mark
W41/W41 blastocyst complementation: A versatile system to study gene function in hematopoietic stem cells
2008) 37th Annual Scientific Meeting featuring the 6th International Neonatal Hematology and Immunology Meeting In Experimental Hematology 36(7, Supplement 1). p.5-5(
- Contribution to journal › Published meeting abstract
-
Mark
Clonal mar-king and genetic manipulation of AGM HSCs
2008) 37th Annual Scientific Meeting featuring the 6th International Neonatal Hematology and Immunology Meeting In Experimental Hematology 36(7, Supplement 1). p.69-69(
- Contribution to journal › Published meeting abstract
-
Mark
Smad4 as a Therapeutic Target in Nup98-HoxA9-Induced Leukemia.
(
- Contribution to journal › Published meeting abstract
-
Mark
Signaling via the Tgf-beta type I receptor Alk5 in heart development
(
- Contribution to journal › Article
-
Mark
A HOXA10-inducible mouse model demonstrates an important role of the initial transforming event in the maintenance of the leukemia
2008) 37th Annual Scientific Meeting featuring the 6th International Neonatal Hematology and Immunology Meeting In Experimental Hematology 36(7, Supplement 1). p.4-5(
- Contribution to journal › Published meeting abstract
-
Mark
Therapeutic effects of bone marrow transplantation for metachromatic leukodystrophy using HOXB4 over-expressing cells
2008) The 13th Annual Meeting 2007 Japan Society of Gene Therapy In Journal of Gene Medicine 10(4). p.476-477(
- Contribution to journal › Published meeting abstract
-
Mark
RPS19 Deficiency Leads to Reduced Proliferation and Increased Apoptosis but Does Not Affect Terminal Erythroid Differentiation in a Cell Line Model of Diamond-Blackfan Anemia
(
- Contribution to journal › Article
-
Mark
Gene therapy of Diamond Blackfan anemia CD34(+) cells leads to improved erythroid development and engraftment following transplantation.
(
- Contribution to journal › Article
-
Mark
Stem cell regulation and host defense: the logic and the paradox.
(
- Contribution to journal › Article
-
Mark
Signaling pathways governing stem cell fate.
(
- Contribution to journal › Scientific review
-
Mark
Towards a better understanding and new therapeutics of osteopetrosis.
(
- Contribution to journal › Scientific review
-
Mark
Successful low-risk hematopoietic cell therapy in a mouse model of type 1 Gaucher disease.
2008) p.1189-1190(
- Contribution to conference › Poster
-
Mark
Delection of the SCN gene cluster on 2q24.4 is associated with severe epilepsy an array-based genotype-phenotype correlation and a comprehensive review of previously published area
(
- Contribution to journal › Article
- 2007
-
Mark
Connecting ribosomes with bone marrow failure
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Fusion gene-mediated truncation of RUNX1 as a potential mechanism underlying disease progression in the 8p11 myeloproliferative syndrome.
(
- Contribution to journal › Article
-
Mark
Human RPS19, the gene mutated in Diamond Blackfan anemia, encodes a ribosomal protein required for the maturation of 40S ribosomal subunits.
(
- Contribution to journal › Article
-
Mark
Hoxa9/hoxb3/hoxb4 compound null mice display severe hematopoietic defects
(
- Contribution to journal › Article
-
Mark
Female mice are more susceptible to developing inflammatory disorders due to impaired transforming growth factor beta signaling in salivary glands
(
- Contribution to journal › Article
-
Mark
Adenoviral vectors for transient gene expression in human primitive hematopoietic cells: Applications and prospects.
(
- Contribution to journal › Scientific review
-
Mark
TGF-beta receptor I conditional knockout mice develop spontaneous squamous cell carcinoma
(
- Contribution to journal › Article
-
Mark
Murine models of acute neuronopathic Gaucher disease
(
- Contribution to journal › Article
-
Mark
Hematopoietic stem cell targeted neonatal gene therapy reverses lethally progressive osteopetrosis in oc/oc mice.
(
- Contribution to journal › Article
-
Mark
Ectopic expression of PAX5 promotes self renewal of bi-phenotypic myeloid progenitors co-expressing myeloid and B-cell lineage associated genes.
(
- Contribution to journal › Article
-
Mark
Diamond-Blackfan anemia: erythropoiesis lost in translation.
(
- Contribution to journal › Scientific review
-
Mark
HOXA10 is a critical regulator for hematopoietic stem cells and erythroid/megakaryocyte development.
(
- Contribution to journal › Article
-
Mark
Alpha10 integrin expression is up-regulated on fibroblast growth factor-2-treated mesenchymal stem cells with improved chondrogenic differentiation potential.
(
- Contribution to journal › Article
-
Mark
Towards Gene Therapy of Osteopetrosis.
2007)(
- Thesis › Doctoral thesis (compilation)
-
Mark
Endoglin is not critical for hematopoietic stem cell engraftment and reconstitution but regulates adult erythroid development
(
- Contribution to journal › Article
-
Mark
Glioma stem cells: Evidence and limitation.
(
- Contribution to journal › Scientific review
-
Mark
Neuron-specific TGF-beta signaling deficiency results in retinal detachment and cataracts in mice
(
- Contribution to journal › Article
-
Mark
Temporal trends of esophageal cancer during 1995-2004 in Nanao Island, an extremely high-risk area in China
(
- Contribution to journal › Article
-
Mark
Smad signaling in hematopoietic stem cell biology
2007)(
- Thesis › Doctoral thesis (compilation)
-
Mark
Smad4 is critical for self-renewal of hematopoietic stem cells.
(
- Contribution to journal › Article
-
Mark
The Role of Hox Transcription Factors in the Regulation of Hematopoiesis
2007) In 2007:26(
- Thesis › Doctoral thesis (compilation)
-
Mark
Adenoviruses Use Lactoferrin as a Bridge for CAR-Independent Binding to and Infection of Epithelial Cells.
(
- Contribution to journal › Article
-
Mark
Diamond-Blackfan Anemia: Erythropoiesis Lost in Translation
2007)(
- Thesis › Doctoral thesis (compilation)
-
Mark
Genetic intratumour heterogeneity in high-grade brain tumours is associated with telomere-dependent mitotic instability.
(
- Contribution to journal › Article
-
Mark
Repopulation of adult and neonatal mice with human hepatocytes : A chimeric animal model
2007) In Proceedings of the National Academy of Sciences of the United States of America 104(51). p.20507-20511(
- Contribution to journal › Article
- 2006
-
Mark
Distribution of vesicular glutamate transporters 1 and 2 in the rat spinal cord, with a note on the spinocervical tract.
(
- Contribution to journal › Article
-
Mark
Human short-term repopulating cells have enhanced telomerase reverse transcriptase expression.
(
- Contribution to journal › Article
-
Mark
Smad5 is dispensable for adult murine hematopoiesis.
(
- Contribution to journal › Article
-
Mark
Neonatal hematopoietic stem cell transplantation cures oc/oc mice from osteopetrosis.
(
- Contribution to journal › Article
-
Mark
Detection of cell cycle- and differentiation stage-dependent human telomerase reverse transcriptase expression in single living cancer cells.
(
- Contribution to journal › Article
-
Mark
Erythropoiesis in the Rps19 disrupted mouse: Analysis of erythropoietin response and biochemical markers for Diamond-Blackfan anemia
(
- Contribution to journal › Article
-
Mark
Epithelial and ectomesenchymal role of the type I TGF-beta receptor ALK5 during facial morphogenesis and palatal fusion
(
- Contribution to journal › Article
-
Mark
Effective cell and gene therapy in a murine model of Gaucher disease.
(
- Contribution to journal › Article
-
Mark
Smad7 promotes self-renewal of hematopoietic stem cells in vivo.
(
- Contribution to journal › Article
-
Mark
A critical developmental role for tgfbr2 in myogenic cell lineages is revealed in mice expressing SM22-Cre, not SMMHC-Cre
(
- Contribution to journal › Article
-
Mark
HOXB4-induced self-renewal of hematopoietic stem cells is significantly enhanced by p21 deficiency.
(
- Contribution to journal › Article
-
Mark
Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects
(
- Contribution to journal › Article
-
Mark
Regulation of hematopoiesis by the Smad signaling pathway
2006)(
- Thesis › Doctoral thesis (compilation)
-
Mark
Cell type- and region- dependent coxsackie adenovirus receptor expression in the central nervous system.
(
- Contribution to journal › Article
-
Mark
Increased expression of cyclin A1 protein is associated with all-trans retinoic acid-induced apoptosis.
(
- Contribution to journal › Article
-
Mark
A road map towards defining the role of Smad signaling in hematopoietic stem cells.
(
- Contribution to journal › Article
- 2005
-
Mark
Identification of conserved amino acids N-terminal of the PKCeC1bdomain crucial for PKCe-mediated induction of neurite outgrowth.
(
- Contribution to journal › Article
-
Mark
Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to beta-amyloid deposition in APP/PS1 double transgenic Alzheimer mice
(
- Contribution to journal › Article
-
Mark
DNA-binding dependent and independent functions of WT1 protein during human hematopoiesis.
(
- Contribution to journal › Article
-
Mark
Quiescence of hematopoietic stem cells and maintenance of the stem cell pool is not dependent on TGF-beta signaling in vivo.
(
- Contribution to journal › Article
-
Mark
Culturing of human tumor cells for use in immune gene tumor therapy
2005) World Federation of Neuro-Oncology Second Quadrennial Meeting and the Sixth Meeting of the European Association for Neuro-Oncology In Neuro-Oncology 7(3). p.371-371(
- Contribution to journal › Published meeting abstract
-
Mark
Deficiency of ribosomal protein S19 in CD34+ cells generated by siRNA blocks erythroid development and mimics defects seen in Diamond-Blackfan anemia.
(
- Contribution to journal › Article
-
Mark
The role of Smad signaling in hematopoiesis.
(
- Contribution to journal › Scientific review
-
Mark
Compound developmental eye disorders following inactivation of TGFbeta signaling in neural-crest stem cells
(
- Contribution to journal › Article
-
Mark
Altered primordial germ cell migration in the absence of transforming growth factor beta signaling via ALK5
(
- Contribution to journal › Article
-
Mark
Gene Transfer to Repopulating Human CD34(+) Cells Using Amphotropic-, GALV-, or RD114-Pseudotyped HIV-1-Based Vectors from Stable Producer Cells.
(
- Contribution to journal › Article
-
Mark
Development of cellular models for ribosomal protein S19 (RPS19)-deficient diamond-blackfan anemia using inducible expression of siRNA against RPS19.
(
- Contribution to journal › Article
-
Mark
TGF-{beta} type II receptor deficient thymocytes develop normally but demonstrate increased CD8+ proliferation in vivo.
(
- Contribution to journal › Article
-
Mark
Gene therapy: efficient targeting of hematopoietic stem cells
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Expression of cyclin A1 and cell cycle proteins in hematopoietic cells and acute myeloid leukemia and links to patient outcome.
(
- Contribution to journal › Article
-
Mark
Gene expression profiling demonstrates that TGF-{beta}1 signals exclusively through receptor complexes involving Alk5 and identifies targets of TGF-{beta} signaling.
(
- Contribution to journal › Article
-
Mark
Inactivation of TGF beta signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome
(
- Contribution to journal › Article