Division of Molecular Medicine and Gene Therapy
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- 2024
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Mark
Hematopoietic stem cell dynamics during regenerative stress
2024) In Lund University, Faculty of Medicine Doctoral Dissertation Series(
- Thesis › Doctoral thesis (compilation)
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Mark
New sickle cell disease drug approved for use in England – here’s how voxelotor works
2024) In The Conversation(
- Contribution to specialist publication or newspaper › Specialist publication article
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Mark
Genomic deletion of Bcl6 differentially affects conventional dendritic cell subsets and compromises Tfh/Tfr/Th17 cell responses
(
- Contribution to journal › Article
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Of gains and losses : SAMD9/SAMD9L and monosomy 7 in myelodysplastic syndrome
(
- Contribution to journal › Scientific review
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Reprogramming Stars #15 : Colliding Cellular Reprogramming Paths— An Interview with Dr. Stefan Stricker
(
- Contribution to journal › Debate/Note/Editorial
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Evidence that CD36 is expressed on red blood cells and constitutes a novel blood group system of clinical importance
(
- Contribution to journal › Article
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In-depth proteomic analysis and structural modelling of protein-protein interactions identify known and novel molecular binding partners for EMP3 in erythroid cells
(
- Contribution to journal › Published meeting abstract
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In vivo dendritic cell reprogramming for cancer immunotherapy
2024) In Science (New York, N.Y.)(
- Contribution to journal › Article
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Mark
How to manage patients with germline DDX41 variants : Recommendations from the Nordic working group on germline predisposition for myeloid neoplasms
(
- Contribution to journal › Article
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Mark
The Impact of Senescent Cells on Limb Regeneration
(
- Contribution to journal › Debate/Note/Editorial
- 2023
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Best Practices to Promote Data Utility and Reuse by the Non-Traditional Model Organism Community
(
- Contribution to journal › Article
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The stem cell-supporting small molecule UM171 triggers Cul3-KBTBD4-mediated degradation of ELM2 domain-harboring proteins
(
- Contribution to journal › Article
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Mark
Single-cell quantification and dose-response of cytosolic siRNA delivery
(
- Contribution to journal › Article
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Mark
Modeling Human Hematopoiesis Using the CRISPR/Cas9 System
2023) In Lund University, Faculty of Medicine Doctoral Dissertation Series(
- Thesis › Doctoral thesis (compilation)
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Mark
MAC-1 marks a quiescent and functionally superior HSC subset during regeneration
(
- Contribution to journal › Article
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Mark
Customizable 3D printed perfusion bioreactor for the engineering of stem cell microenvironments
(
- Contribution to journal › Article
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Mark
Reprogramming Stars #10 : Modeling Cancer with Cellular Reprogramming-An Interview with Dr. Dung-Fang Lee
(
- Contribution to journal › Debate/Note/Editorial
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Mark
Evaluation of genetic demultiplexing of single-cell sequencing data from model species
(
- Contribution to journal › Article
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Mark
IRF1 regulates self-renewal and stress-responsiveness to support hematopoietic stem cell maintenance
2023)(
- Working paper/Preprint › Preprint in preprint archive
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Mark
Astrocyte dysfunction and neuronal network hyperactivity in a CRISPR engineered pluripotent stem cell model of frontotemporal dementia
(
- Contribution to journal › Article
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Mark
Restoring tumor immunogenicity with dendritic cell reprogramming
(
- Contribution to journal › Article
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Mark
Reprogramming Stars #11 : Teaming Up to Uncover the Epitranscriptomics of Reprogramming - An Interview with Dr. Miguel Fidalgo and Dr. Diana Guallar
(
- Contribution to journal › Debate/Note/Editorial
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Mark
Reprogramming Stars #12 : At the Heart of In Vivo Reprogramming- An Interview with Dr. Li Qian
(
- Contribution to journal › Debate/Note/Editorial
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Mark
Assessing efficacy and immune-stimulatory effects of tumor-derived dendritic cell reprogramming using immuno-competent 3D tumor spheroid model
2023) American Association for Cancer Research Annual Meeting 2023 In Cancer Research 83(7 Supplement).(
- Contribution to journal › Published meeting abstract
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Mark
GATA2 mitotic bookmarking is required for definitive haematopoiesis
(
- Contribution to journal › Article
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Mark
Recombinant α
1-Microglobulin (rA1M) Protects against Hematopoietic and Renal Toxicity, Alone and in Combination with Amino Acids, in a
177Lu-DOTATATE Mouse Radiation Model.
(
- Contribution to journal › Article
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Mark
Ciclopirox Ethanolamine Preserves the Immature State of Human HSCs by Mediating Intracellular Iron Content
(
- Contribution to journal › Article
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Mark
Challenging the definition of a blood group: Proposal to make CD36 a novel blood group system based on a case report and pre-existing genetic, proteomic and clinical data
(
- Contribution to journal › Published meeting abstract
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Unleashing Ascl1 : Exploring Cross-Lineage Potential in Reprogramming and Regenerative Frontiers
(
- Contribution to journal › Article
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AKT1 induces Nanog promoter in a SUMOylation-dependent manner in different pluripotent contexts
(
- Contribution to journal › Article
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Novel pathological variants of NHP2 affect N-terminal domain flexibility, protein stability, H/ACA Ribonucleoprotein (RNP) complex formation and telomerase activity
(
- Contribution to journal › Article
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Mark
IRF1 regulates self-renewal and stress responsiveness to support hematopoietic stem cell maintenance
(
- Contribution to journal › Article
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Functional and molecular profiling of hematopoietic stem cells during regeneration
(
- Contribution to journal › Article
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Programming human cell fate : overcoming challenges and unlocking potential through technological breakthroughs
(
- Contribution to journal › Article
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Mark
Reprogramming Cancer Cells to Antigen-presenting Cells
(
- Contribution to journal › Article
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Mark
High-Throughput Drug Screening Revealed That Ciclopirox Olamine Can Engender Gastric Cancer Stem-like Cells
(
- Contribution to journal › Article
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Mark
Orchestrating an immune response to cancer with cellular reprogramming
2023) In Genes and Immunity(
- Contribution to journal › Article
-
Mark
Perspectives of current understanding and therapeutics of Diamond-Blackan anemia
2023) In Leukemia(
- Contribution to journal › Scientific review
-
Mark
Restoring antitumor immunity with dendritic cell reprogramming strategies. Reprogramming cancer cells to antigen-presenting cells.
2023) In Lund University, Faculty of Medicine Doctoral Dissertation Series(
- Thesis › Doctoral thesis (compilation)
-
Mark
Combined GLUT1 and OXPHOS inhibition eliminates acute myeloid leukemia cells by restraining their metabolic plasticity
(
- Contribution to journal › Article
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Mark
Engineered human Diamond-Blackfan anemia disease model confirms therapeutic effects of clinically applicable lentiviral vector at single-cell resolution
(
- Contribution to journal › Article
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Mark
New insight into the causes, consequences, and correction of hematopoietic stem cell aging
(
- Contribution to journal › Scientific review
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Mark
Label-FreeHigh-ResolutionPhotothermalOpticalInfraredSpectroscopyfor Spatiotemporal Chemica lAnalysis in Fresh, Hydrated Living Tissues and Embryos
2023) In Journal of the American Chemical Society(
- Contribution to journal › Article
-
Mark
Reprogramming Stars #13 : Establishing Connections with Cellular Reprogramming–An Interview with Dr. Daniella Rylander Ottosson
(
- Contribution to journal › Debate/Note/Editorial
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Mark
Mechanisms Underlying the Specification of Definitive Hematopoiesis
2023) In Lund University, Faculty of Medicine Doctoral Dissertation Series(
- Thesis › Doctoral thesis (compilation)
- 2022
-
Mark
Blood in a Lab: Using Immortalized Erythroid Cell Lines as a Source for Blood Transfusion
2022) In Lund University, Faculty of Medicine Doctoral Dissertation Series(
- Thesis › Doctoral thesis (compilation)
-
Mark
Single-cell transcriptional profiling informs efficient reprogramming of human somatic cells to cross-presenting dendritic cells
(
- Contribution to journal › Article
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Mark
Rebuilding limbs, one cell at a time
(
- Contribution to journal › Article
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Mark
Induction of enucleation in primary and immortalized erythroid cells
(
- Contribution to journal › Scientific review
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Small Molecule Screening of Primary Human Acute Myeloid Leukemia Using Co-culture and Multiplexed FACS Analysis
(
- Contribution to journal › Article
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Mark
A somatic mutation in moesin drives progression into acute myeloid leukemia
(
- Contribution to journal › Article
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Mark
Reprogramming Stars #6 : A Venture Based in Cellular Reprogramming-An Interview with Dr. Cristiana Pires
(
- Contribution to journal › Debate/Note/Editorial
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Mark
Reprogramming Stars #5 : Regeneration, a Natural Reprogramming Process-An Interview with Dr. Nicholas Leigh
(
- Contribution to journal › Debate/Note/Editorial
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Mark
Compositions, constructs and vectors for cell reprogramming (NK cell reprogramming).
2022) WO2022129542(
- Patent › Patent
-
Mark
Ciliated (FOXJ1+) Cells Display Reduced Ferritin Light Chain in the Airways of Idiopathic Pulmonary Fibrosis Patients
(
- Contribution to journal › Article
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Mark
Concurrent stem- and lineage-affiliated chromatin programs precede hematopoietic lineage restriction
(
- Contribution to journal › Article
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Mark
Genome-wide association study on 13 167 individuals identifies regulators of blood CD34+cell levels
(
- Contribution to journal › Article
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Mark
Inducing synthetic lethality for selective targeting of acute myeloid leukemia cells harboring STAG2 mutations
(
- Contribution to journal › Letter
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Mark
Combinatorial gene targeting in primary human hematopoietic stem and progenitor cells
(
- Contribution to journal › Article
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Mark
Nuclear stabilization of p53 requires a functional nucleolar surveillance pathway
(
- Contribution to journal › Article
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Mark
FOXO1 regulates pentose phosphate pathway-mediated induction of developmental erythropoiesis
(
- Contribution to journal › Article
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Mark
Small Molecules Pushing Erythroid/Megakaryocyte Cell Specification Boundaries
(
- Contribution to journal › Article
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Mark
The 2022 International Society for Stem Cell Research (ISSCR) Annual Meeting : Celebrating 20 Years of Achievements
(
- Contribution to journal › Debate/Note/Editorial
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Mark
BMPR1a Is Required for the Optimal TGFβ1-Dependent CD207+ Langerhans Cell Differentiation and Limits Skin Inflammation through CD11c+ Cells
(
- Contribution to journal › Article
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New hallmarks of ageing : a 2022 Copenhagen ageing meeting summary
(
- Contribution to journal › Article
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Reprogramming Stars #9 : Spacing Out Cellular Reprogramming-An Interview with Dr. Valentina Fossati
(
- Contribution to journal › Debate/Note/Editorial
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Mark
Site-specific CRISPR-based mitochondrial DNA manipulation is limited by gRNA import
(
- Contribution to journal › Article
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Mark
Stem cells, cell therapies, and bioengineering in lung biology and disease 2021
(
- Contribution to journal › Scientific review
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Mark
Unravelling mechanisms of hematopoietic stem cell expansion
2022) In Lund University, Faculty of Medicine Doctoral Dissertation Series(
- Thesis › Doctoral thesis (compilation)
-
Mark
Inflammatory Alveolar Type 2 Cells in Chronic Obstructive Pulmonary Disease : Impairing or Improving Disease Outcome?
(
- Contribution to journal › Debate/Note/Editorial
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Mark
Eliciting Anti-Tumor Immunity by Reprogramming Cancer Cells to Type 1 Conventional Dendritic Cells
2022) European Association for Cancer Research 2022 - Congress(
- Contribution to conference › Poster
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Mark
Harnessing Dendritic Cell Reprogramming to Elucidate Mechanisms of Tumor Immunity
2022) Lund Stem Cell Center Retreat(
- Contribution to conference › Poster
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Mark
Dynamically upregulated mast cell CPA3 patterns in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis
(
- Contribution to journal › Article
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RNAi Screen Identifies MTA1 as an Epigenetic Modifier of Differentiation Commitment in Human HSPCs
(
- Contribution to journal › Article
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Mark
Cell-type profiling in salamanders identifies innovations in vertebrate forebrain evolution
(
- Contribution to journal › Article
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CD244 expression represents functional decline of murine hematopoietic stem cells after in vitro culture
(
- Contribution to journal › Article
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Human CIDEC transgene improves lipid metabolism and protects against high-fat diet–induced glucose intolerance in mice
(
- Contribution to journal › Article
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Mark
Schlafen2 is a regulator of quiescence in adult murine hematopoietic stem cells
(
- Contribution to journal › Article
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Mark
Regulome analysis in B-acute lymphoblastic leukemia exposes Core Binding Factor addiction as a therapeutic vulnerability
(
- Contribution to journal › Article
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Mark
Successful gene therapy of Diamond-Blackfan anemia in a mouse model and human CD34+ cord blood hematopoietic stem cells using a clinically applicable lentiviral vector
(
- Contribution to journal › Article
-
Mark
Overcoming delivery challenges in stem cell biology with nanotechnology
2022) In Lund University, Faculty of Medicine Doctoral Dissertation Series(
- Thesis › Doctoral thesis (compilation)
-
Mark
Transcriptomic analysis of functional diversity of human umbilical cord blood hematopoietic stem/progenitor cells in erythroid differentiation
(
- Contribution to journal › Article
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Mark
HMGA1 has predictive value in response to chemotherapy in gastric cancer
(
- Contribution to journal › Article
-
Mark
Reprogramming primary melanoma cells to dendritic cell fate enhances tumor immunogenicity
2022) SITC Society for Immunotherapy of Cancer 2022(
- Contribution to conference › Poster
-
Mark
Restoring tumor immunogenicity with dendritic cell reprogramming
(
- Contribution to journal › Published meeting abstract
-
Mark
Direct Reprogramming of Mouse and Human Fibroblasts into Conventional Dendritic Cells Type 1
(
- Contribution to journal › Published meeting abstract
-
Mark
Targeting elevated heme levels to treat a mouse model for Diamond-Blackfan Anemia
(
- Contribution to journal › Article
-
Mark
Pyruvate metabolism guides definitive lineage specification during hematopoietic emergence
(
- Contribution to journal › Article
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Mark
Establishment of an immortalized human erythroid cell line sustaining differentiation potential without inducible gene expression system
(
- Contribution to journal › Article
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Mark
Epicardium-derived cells organize through tight junctions to replenish cardiac muscle in salamanders
(
- Contribution to journal › Article
-
Mark
Modeling normal and malignant hematopoiesis in vitro. To screen for extrinsic regulators and differentiation therapy.
2022) In Lund University, Faculty of Medicine Doctoral Dissertation Series(
- Thesis › Doctoral thesis (compilation)
-
Mark
Novel Insights into Haematopoietic Stem Cell Regulation and Function
2022)(
- Thesis › Doctoral thesis (compilation)
-
Mark
The Human Lung Epithelium in Health and Disease
2022) In Lund University, Faculty of Medicine Doctoral Dissertation Series(
- Thesis › Doctoral thesis (compilation)
-
Mark
Reprogramming Stars #7 : Dynamic Pluripotent Stem Cell States and Their Applications-An Interview with Dr. Jun Wu
(
- Contribution to journal › Debate/Note/Editorial
-
Mark
Reprogramming Stars #8 : A Synthetic Biology Approach to Cellular Reprogramming-An Interview with Dr. Katie Galloway
(
- Contribution to journal › Debate/Note/Editorial
- 2021
-
Mark
Mitochondrial Potentiation Ameliorates Age-Related Heterogeneity in Hematopoietic Stem Cell Function
(
- Contribution to journal › Article
-
Mark
Isolation of high yield and quality RNA from human precision-cut lung slices for RNA-sequencing and computational integration with larger patient cohorts
(
- Contribution to journal › Article
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Mark
Human radical scavenger α1-microglobulin protects against hemolysis in vitro and α1-microglobulin knockout mice exhibit a macrocytic anemia phenotype
(
- Contribution to journal › Article
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Mark
Combinatorial molecule screening identifies a novel diterpene and the BET inhibitor CPI-203 as differentiation inducers of primary acute myeloid leukemia cells
(
- Contribution to journal › Article
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Mark
Identification of potential chemical compounds enhancing generation of enucleated cells from immortalized human erythroid cell lines
(
- Contribution to journal › Article